Mechanism of action
Beneficial action and toxicities of PG synthesis inhibition
Common properties of all NSAIDs
Choice of analgesic after certain endodontic procedures
Pain management strategy
Flexible prescription plan
Dose – 10-20 mg OD
Commercial name – Valed, Valus, Vorth, Bextra
Banned –7 April 2005.
Other drugs banned by FDA
1) Effectiveness of prophylactic use of refecoxib is comparison
with ibuprofen on postendodontic pain. JOE. Jan 2003, Vol.
29, No. 1, pg. 62-64.
2) Evaluation of meloxicam (cox-2 inhibitor) for management
of post operative endodontic pain – A double blind placebo
controlled study. JOE, Oct 03, Vol. 29, No. 10, Pg. 634-637.
3) The efficacy of pain control following nonsurgical root canal
treatment using ibuprofen in a combination of ibuprofen
and acetaminophen in a randomized, double-blind, placebo
controlled study. IEJ, 2004, Vol. 37, Pg. 531-541.www.indiandentalacademy.com