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Pattern of Respiratory Illnesses
    in Hong Kong
       Dr WM Chan
       President,
       Hong Kong Thoracic Society


          Hong Kong Thoracic Society
1
Burden of Lung Disease Project:
    The Significant Findings
     In 2005, respiratory disease was ranked as the top
      cause of mortality and hospitalization in Hong Kong.
     Respiratory diseases accounted for 16% of all
      inpatient bed-days.
     Although there has been a slow decline in respiratory
      mortality rate in the past decade, there has been no
      change in respiratory hospitalization rates.
     Respiratory diseases, therefore, have accounted for
      the largest share of the health-care burden locally.

           Hong Kong Thoracic Society
2
Respiratory Diseases in 2005
    %     of  Resp Mortalit Hospitalizati In-patient
Diseases             y          on        bed days
 Respiratory
infection
                    39.0       41.3         37.2
 Lung Cancer        33.2       5.7           9.2
 COPD               17.9       14.6         20.5
 Tuberculosis       2.4        3.9           7.1
 Bronchiectasis     1.7        1.7           1.7
 Asthma             0.9        5.7           2.6
 Pneumoconiosis     0.4        0.2           0.2
 OSA                 0         5.5           0.7
 Others             4.5        21.5         20.7
          Hong Kong Thoracic Society
3
Air Pollution vs Asthma: Methods
     Retrospective ecological study from Jan 2000 to December 2005
      (Dr F Ko)
     Daily emergency hospital admissions to 15 major hospitals in HK
      for acute asthma (Hospital Authority)
     Total 69,716 admissions for asthma from January 2000 to
      December 2005
        Mean daily admissions = 31.9
     Every 10µg/m3 increase in air pollutants was associated with:

    Air pollutants                  Increased risk of asthma hospitalization

    O3                                                                  3.4%
    NO2                                                                 2.8%
    PM10                                                                1.9%
    PM2.5                                                               2.1%

                Hong Kong Thoracic Society
4
Daily summary of the number of asthma admissions,
meterological and pollutant data
                                                    Mean               SD
    Admissions for asthma                                  31.9        10.9
    Temperature                                            23.4        5.1
    Relative humidity                                      72.2        13.3
    NO2 (µg/m3)                                            53.2        19.3
    O3 (µg/m3)                                             43.4        23.7
    PM10 (µg/m3)                                           52.5        27.1
    PM2.5 (µg/m3)                                          36.4        21.1

    SO2 (µg/m3)                                            18.8        13.1

                                            WHO (2006) recommended guideline
                                            NO2            40ug/m3 annual mean
Ref: Clinical and
Experimental Allergy 2007:                  O3             100ug/m3 8-hr mean
37:1312-13                                  SO2            20ug/m3 24-hr mean
               Hong Kong Thoracic Society   PM2.5          25ug/m3 24-hr mean
5
                                            PM10           50ug/m3 24-hr mean
Data on COPD:
    Retrospective ecological study Jan 2000 to Dec 2004
    Air pollutants                      Increased risk of COPD hospitalization

    O3                                                   3.4%

    NO2                                                  2.6%

    PM10                                                 2.4%
    PM2.5                                                3.1%
    SO2                                                  0.7%

     Significant association between hospital admissions for acute
      exacerbation of COPD and an increase in 10mcg/m³ of all the 5
      pollutants (O3, NO3, PM10, PM2.5 and SO2) was observed
     O3 contributed to the greatest risk of hospital COPD admissions
     Public health measures are urgently needed to improve air quality in
      Hong Kong

                Hong Kong Thoracic Society                Thorax. 2007 Sep;62(9):748-9
6

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Civic Exchange - 2009 The Air We Breathe Conference - Patterns of Respiratory Illness in Hong Kong, presented by Dr WM Chan (Hong Kong Thoracic Society)

  • 1. Pattern of Respiratory Illnesses in Hong Kong Dr WM Chan President, Hong Kong Thoracic Society Hong Kong Thoracic Society 1
  • 2. Burden of Lung Disease Project: The Significant Findings  In 2005, respiratory disease was ranked as the top cause of mortality and hospitalization in Hong Kong.  Respiratory diseases accounted for 16% of all inpatient bed-days.  Although there has been a slow decline in respiratory mortality rate in the past decade, there has been no change in respiratory hospitalization rates.  Respiratory diseases, therefore, have accounted for the largest share of the health-care burden locally. Hong Kong Thoracic Society 2
  • 3. Respiratory Diseases in 2005 % of Resp Mortalit Hospitalizati In-patient Diseases y on bed days Respiratory infection 39.0 41.3 37.2 Lung Cancer 33.2 5.7 9.2 COPD 17.9 14.6 20.5 Tuberculosis 2.4 3.9 7.1 Bronchiectasis 1.7 1.7 1.7 Asthma 0.9 5.7 2.6 Pneumoconiosis 0.4 0.2 0.2 OSA 0 5.5 0.7 Others 4.5 21.5 20.7 Hong Kong Thoracic Society 3
  • 4. Air Pollution vs Asthma: Methods  Retrospective ecological study from Jan 2000 to December 2005 (Dr F Ko)  Daily emergency hospital admissions to 15 major hospitals in HK for acute asthma (Hospital Authority)  Total 69,716 admissions for asthma from January 2000 to December 2005  Mean daily admissions = 31.9 Every 10µg/m3 increase in air pollutants was associated with: Air pollutants Increased risk of asthma hospitalization O3 3.4% NO2 2.8% PM10 1.9% PM2.5 2.1% Hong Kong Thoracic Society 4
  • 5. Daily summary of the number of asthma admissions, meterological and pollutant data Mean SD Admissions for asthma 31.9 10.9 Temperature 23.4 5.1 Relative humidity 72.2 13.3 NO2 (µg/m3) 53.2 19.3 O3 (µg/m3) 43.4 23.7 PM10 (µg/m3) 52.5 27.1 PM2.5 (µg/m3) 36.4 21.1 SO2 (µg/m3) 18.8 13.1 WHO (2006) recommended guideline NO2 40ug/m3 annual mean Ref: Clinical and Experimental Allergy 2007: O3 100ug/m3 8-hr mean 37:1312-13 SO2 20ug/m3 24-hr mean Hong Kong Thoracic Society PM2.5 25ug/m3 24-hr mean 5 PM10 50ug/m3 24-hr mean
  • 6. Data on COPD: Retrospective ecological study Jan 2000 to Dec 2004 Air pollutants Increased risk of COPD hospitalization O3 3.4% NO2 2.6% PM10 2.4% PM2.5 3.1% SO2 0.7%  Significant association between hospital admissions for acute exacerbation of COPD and an increase in 10mcg/m³ of all the 5 pollutants (O3, NO3, PM10, PM2.5 and SO2) was observed  O3 contributed to the greatest risk of hospital COPD admissions  Public health measures are urgently needed to improve air quality in Hong Kong Hong Kong Thoracic Society Thorax. 2007 Sep;62(9):748-9 6