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Creating a Screening Algorithm for
Sexually Transmitted Infections:
Baiye N. Orock, MPH, U of S School of
Public Health
Dr. Mark Vooght, MHO, FHHR
April 2015
2009 2010 2011 2012 2013 2014
FHHR 28.5 22.9 28.0 26.0 19.7 29.5
SK 46.8 48.8 52.1 52.4 53.5
Target 24.5 24.5 24.5 24.5 24.5 24.5
0
10
20
30
40
50
60
Rateper10,000
Chlamydia Rates (All Ages) per 10,000 Population for FHHR and SK,
2009-2014, Target 2013/14
Target is based
on average rate
for 2009-14,
and a 5%
Updated: Feb 2, 2015
Senior Leader Chart Maintenance Chart Developer
Dr. Vooght Epidemiologist Epidemiologist
Q3
2012/13
Q4
2012/13
Q1
2013/14
Q2
2013/14
Q3
2013/14
Q4
2013/14
Q1
2014/15
Q2
2014/15
Q3
2014/15
Number tests done 752 679 665 710 782 858 842 891 810
Positivity rate (%) 3.3 4.6 4.2 3.5 3.3 2.9 5.0 4.9 6.9
Target (%) 3.3 3.3 3.3 3.3 3.3 3.3 3.3 3.3 3.3
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
0
100
200
300
400
500
600
700
800
900
1000
Positivityrate(%)
NumberofTests
FHHR Chlamydia Positivity Rate (%) - Tests Done,
Q3 2012/13 to Q3 2014/15
Updated: Jan 6, 2015
Senior Leader Chart Maintenance
Dr. Vooght T. Schellenberg
Target is based on average rate
for Q1 2012/13 to Q4 2013/14,
and a 20% decrease
2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014
FHHR HIV Rate 1.8 0 1.9 1.9 1.8 3.7 3.6 9 5.5 1.8 1.8
SK HIV Rate 4 2.6 4 5.5 8.1 10.2 12.7 17.1 19.4 16.2 17.2 16.2 12 9.6
0
5
10
15
20
25Rateper100,000
HIV Rates per 100,000 Population for FHHR and SK, 2001 to 2014 Updated: Feb 12, 2015
Sponsor Owner
Dr. Vooght C. Ward
Issue: Develop an Evidence-based STI
Screening Decision Tool
• The development of an STI screening decision
tool to be used by healthcare providers
• Screening to be risk-based ?
• This to be informed by conducting a literature
review
RESEARCH QUESTIONS:
• 1. What are the evidence-based algorithms for
identifying sexually transmitted infection risk
factors and testing requirements in adult patients
presenting to primary care?
• 2. What are the evidence-based guidelines
regarding optimal risk grouping, age cohorts, risk
categories, and timing of screening for sexually
transmitted infections in adult patients?
Asymptomatic Patients:
Symptomatic Patients
Utilizing the Evidence:
• We predominantly used 6 STI Guidelines, to
create a screening algorithm
• Risk-based
Offer routine screening (Chlamydia, Gonorrhea, HIV & Syphilis) to ALL sexually active clients.
Yes
No
Syndromic
management1 .
Routine
screening plus2
HBV, HCV.
As part of investigation,
consider routine screening
plus risk based screening
below
Are there any STI-related
Signs & Symptoms?
Female Male
Is client pregnant?
Yes No
ALL < 25 &/or at high risk* ?
< 30 & sexually active?
Yes No
Routine
screening
plus3 HBV
Routine
screening
plus4 HBV, HCV.
Routine
screening
Risk - based
screening
Yes
SEXUALLY TRANSMITTED INFECTION/BLOOD BORNE PARTHOGEN (STI/BBP) SCREENING ALGORITHM
Is this visit related to a sexual health concern?
Routine screening & Other2
Add HAV5, HBV5, HCV.
Add HBV5 .
Add HBV5 ; consider Chancroid#, LGV#, Granuloma inguinale #
Add HBV5, HCV.
consider Parasitic7 STI
Using IV drugs or other addictive substances?
Same-sex partner( MSM6/WSW) or bisexual?
Sex trade workers and/or their clients?
Recently in an STI endemic area8?
Are there any other risk factors9?
Client requests STI screening
Risk-Based Screening:
Important: Go through ALL questions as the
client may be in more than one risk
category:
SUPERSCRIPT:
1 - Focused primary and secondary prevention counselling; treatment as necessary and partner follow up .
2 – Offer routine screening and/or screening based on institutional or local prevalence of STI.
3 – For all pregnant women, Chlamydia and Gonorrhea screening recommended for first prenatal visit. If positive, re-test within 3
– 6 months.
4 – For all pregnant women at high risk, Chlamydia and Gonorrhea screening recommended for first and third trimesters. Also
repeat HIV serology during labour for those at high-risk.
5 - Offer serological screening and immunize accordingly following Hepatitis A and B immunization recommendations as per the
Saskatchewan Immunization Manual, available at: http://www.health.gov.sk.ca/sim-chapter10
6 – Sample collection for MSM should be at site of receptive/penetrative oral or anal sex (Pharyngeal, urethral and/or rectal).
7 – Examples of a parasitic STI include trichomoniasis, pubic lice and scabies. Screening may be necessary only for trichomoniasis.
8 – For a list/map of STI endemic regions/countries, refer to:
http://www.who.int/gho/hiv/hiv_013.jpg --- HIV -endemic regions
http://www.cdc.gov/immigrantrefugeehealth/guidelines/domestic/sexually-transmitted-diseases.html -- Syphilis- endemic
regions (see Table 3).
NB: “The largest number of new infections occurs in the region of South and Southeast Asia, followed by sub-Saharan Africa,
Latin America, and the Caribbean” CDC, 2011.
SEXUALLY TRANSMITTED INFECTION/BLOOD BORNE PARTHOGEN (STI/BBP) SCREENING ALGORITHM
STI /BBP Screening Algorithm
STI /BBP Screening Algorithm
9 - OTHER RISK FACTORS:
-Sexual contact with person(s) with a known STI.
-A new sexual partner or more than two sexual partners in the past year.
-Serially monogamous individuals.
-No contraception or the use of only non-barrier methods of contraception
(i.e. no condoms).
-Any individual engaging in unsafe (i.e. Unprotected) sexual practices
-“Survival sex”: exchanging sex for money, drugs, shelter or food.
-Anonymous or internet sexual partnering.
-Victims of sexual abuse.
-Previous history of STI
-Living in an area with high prevalence of STI.
HAV = Hepatitis A Virus.
HBV = Hepatitis B Virus.
HCV = Hepatitis C Virus.
HIV = Human Immunodeficiency Virus.
LGV = Lymphogranuloma venerum.
#- Use professional discretion (i.e. screen based
on prevalence of STIs in the countries recently
visited).
*- presence of one or more risk factors for
STI/BBP.
ABBREVIATIONS
Utility of the Screening Tool:
• Used in concert with the STI Syndromic-based
risk-assessment tool
Sexual health-related visit
Presence of No symptoms
signs/symptoms but
concerns
Non-Sexual health-related visit
Brief risk assessment (See back of page)
Risk identified No risk identified
*Routine Asymptomatic screening
Minimal prevention counseling
Maintenance of safer practices
Discussion of future risk avoidance
Focused risk assessment
Focused prevention counseling
Syndromic management
Testing/screening
Treatment and partner follow-up
STI Risk Assessment in Primary Care Settings
Testing Code Key
Survey Conclusion & Recommendations:
Recommendations
 Development of an accompanying STI risk-based client questionnaire
 Creation of a partnership with eHealth to develop a province wide format for the Electronic
Medical Records (EMR) system.
 Have strategically located patient-specific posters or monitor displays, with appropriate STI
prevention and control messages (especially risk factors), at waiting areas in physician offices
and health clinics
 Of the Physicians, NPs and PHNs who participated in an implementation survey of the
developed tools, (screening algorithm and clinical assessment tool):
- 92% found them easy to use,
- 46% found the algorithm cluttered
- 100% rated the content as good to excellent, and

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Cadth 2015 c4 symp 13 april 2015_vooght

  • 1. Creating a Screening Algorithm for Sexually Transmitted Infections: Baiye N. Orock, MPH, U of S School of Public Health Dr. Mark Vooght, MHO, FHHR April 2015
  • 2. 2009 2010 2011 2012 2013 2014 FHHR 28.5 22.9 28.0 26.0 19.7 29.5 SK 46.8 48.8 52.1 52.4 53.5 Target 24.5 24.5 24.5 24.5 24.5 24.5 0 10 20 30 40 50 60 Rateper10,000 Chlamydia Rates (All Ages) per 10,000 Population for FHHR and SK, 2009-2014, Target 2013/14 Target is based on average rate for 2009-14, and a 5% Updated: Feb 2, 2015 Senior Leader Chart Maintenance Chart Developer Dr. Vooght Epidemiologist Epidemiologist
  • 3. Q3 2012/13 Q4 2012/13 Q1 2013/14 Q2 2013/14 Q3 2013/14 Q4 2013/14 Q1 2014/15 Q2 2014/15 Q3 2014/15 Number tests done 752 679 665 710 782 858 842 891 810 Positivity rate (%) 3.3 4.6 4.2 3.5 3.3 2.9 5.0 4.9 6.9 Target (%) 3.3 3.3 3.3 3.3 3.3 3.3 3.3 3.3 3.3 0.0 1.0 2.0 3.0 4.0 5.0 6.0 7.0 8.0 0 100 200 300 400 500 600 700 800 900 1000 Positivityrate(%) NumberofTests FHHR Chlamydia Positivity Rate (%) - Tests Done, Q3 2012/13 to Q3 2014/15 Updated: Jan 6, 2015 Senior Leader Chart Maintenance Dr. Vooght T. Schellenberg Target is based on average rate for Q1 2012/13 to Q4 2013/14, and a 20% decrease
  • 4. 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 FHHR HIV Rate 1.8 0 1.9 1.9 1.8 3.7 3.6 9 5.5 1.8 1.8 SK HIV Rate 4 2.6 4 5.5 8.1 10.2 12.7 17.1 19.4 16.2 17.2 16.2 12 9.6 0 5 10 15 20 25Rateper100,000 HIV Rates per 100,000 Population for FHHR and SK, 2001 to 2014 Updated: Feb 12, 2015 Sponsor Owner Dr. Vooght C. Ward
  • 5. Issue: Develop an Evidence-based STI Screening Decision Tool • The development of an STI screening decision tool to be used by healthcare providers • Screening to be risk-based ? • This to be informed by conducting a literature review
  • 6. RESEARCH QUESTIONS: • 1. What are the evidence-based algorithms for identifying sexually transmitted infection risk factors and testing requirements in adult patients presenting to primary care? • 2. What are the evidence-based guidelines regarding optimal risk grouping, age cohorts, risk categories, and timing of screening for sexually transmitted infections in adult patients?
  • 7.
  • 10. Utilizing the Evidence: • We predominantly used 6 STI Guidelines, to create a screening algorithm • Risk-based
  • 11. Offer routine screening (Chlamydia, Gonorrhea, HIV & Syphilis) to ALL sexually active clients. Yes No Syndromic management1 . Routine screening plus2 HBV, HCV. As part of investigation, consider routine screening plus risk based screening below Are there any STI-related Signs & Symptoms? Female Male Is client pregnant? Yes No ALL < 25 &/or at high risk* ? < 30 & sexually active? Yes No Routine screening plus3 HBV Routine screening plus4 HBV, HCV. Routine screening Risk - based screening Yes SEXUALLY TRANSMITTED INFECTION/BLOOD BORNE PARTHOGEN (STI/BBP) SCREENING ALGORITHM Is this visit related to a sexual health concern?
  • 12. Routine screening & Other2 Add HAV5, HBV5, HCV. Add HBV5 . Add HBV5 ; consider Chancroid#, LGV#, Granuloma inguinale # Add HBV5, HCV. consider Parasitic7 STI Using IV drugs or other addictive substances? Same-sex partner( MSM6/WSW) or bisexual? Sex trade workers and/or their clients? Recently in an STI endemic area8? Are there any other risk factors9? Client requests STI screening Risk-Based Screening: Important: Go through ALL questions as the client may be in more than one risk category:
  • 13. SUPERSCRIPT: 1 - Focused primary and secondary prevention counselling; treatment as necessary and partner follow up . 2 – Offer routine screening and/or screening based on institutional or local prevalence of STI. 3 – For all pregnant women, Chlamydia and Gonorrhea screening recommended for first prenatal visit. If positive, re-test within 3 – 6 months. 4 – For all pregnant women at high risk, Chlamydia and Gonorrhea screening recommended for first and third trimesters. Also repeat HIV serology during labour for those at high-risk. 5 - Offer serological screening and immunize accordingly following Hepatitis A and B immunization recommendations as per the Saskatchewan Immunization Manual, available at: http://www.health.gov.sk.ca/sim-chapter10 6 – Sample collection for MSM should be at site of receptive/penetrative oral or anal sex (Pharyngeal, urethral and/or rectal). 7 – Examples of a parasitic STI include trichomoniasis, pubic lice and scabies. Screening may be necessary only for trichomoniasis. 8 – For a list/map of STI endemic regions/countries, refer to: http://www.who.int/gho/hiv/hiv_013.jpg --- HIV -endemic regions http://www.cdc.gov/immigrantrefugeehealth/guidelines/domestic/sexually-transmitted-diseases.html -- Syphilis- endemic regions (see Table 3). NB: “The largest number of new infections occurs in the region of South and Southeast Asia, followed by sub-Saharan Africa, Latin America, and the Caribbean” CDC, 2011. SEXUALLY TRANSMITTED INFECTION/BLOOD BORNE PARTHOGEN (STI/BBP) SCREENING ALGORITHM STI /BBP Screening Algorithm
  • 14. STI /BBP Screening Algorithm 9 - OTHER RISK FACTORS: -Sexual contact with person(s) with a known STI. -A new sexual partner or more than two sexual partners in the past year. -Serially monogamous individuals. -No contraception or the use of only non-barrier methods of contraception (i.e. no condoms). -Any individual engaging in unsafe (i.e. Unprotected) sexual practices -“Survival sex”: exchanging sex for money, drugs, shelter or food. -Anonymous or internet sexual partnering. -Victims of sexual abuse. -Previous history of STI -Living in an area with high prevalence of STI. HAV = Hepatitis A Virus. HBV = Hepatitis B Virus. HCV = Hepatitis C Virus. HIV = Human Immunodeficiency Virus. LGV = Lymphogranuloma venerum. #- Use professional discretion (i.e. screen based on prevalence of STIs in the countries recently visited). *- presence of one or more risk factors for STI/BBP. ABBREVIATIONS
  • 15. Utility of the Screening Tool: • Used in concert with the STI Syndromic-based risk-assessment tool
  • 16. Sexual health-related visit Presence of No symptoms signs/symptoms but concerns Non-Sexual health-related visit Brief risk assessment (See back of page) Risk identified No risk identified *Routine Asymptomatic screening Minimal prevention counseling Maintenance of safer practices Discussion of future risk avoidance Focused risk assessment Focused prevention counseling Syndromic management Testing/screening Treatment and partner follow-up STI Risk Assessment in Primary Care Settings
  • 18. Survey Conclusion & Recommendations: Recommendations  Development of an accompanying STI risk-based client questionnaire  Creation of a partnership with eHealth to develop a province wide format for the Electronic Medical Records (EMR) system.  Have strategically located patient-specific posters or monitor displays, with appropriate STI prevention and control messages (especially risk factors), at waiting areas in physician offices and health clinics  Of the Physicians, NPs and PHNs who participated in an implementation survey of the developed tools, (screening algorithm and clinical assessment tool): - 92% found them easy to use, - 46% found the algorithm cluttered - 100% rated the content as good to excellent, and

Editor's Notes

  1. Accompanying risk-based client questionnaire could be handed for patients to fill while they wait to see physician on ones they meet the physician, hand the sheet ann the physician could order testing as required. –Time saving measure  Increase adoption of screening. Evaluation: by describing STI/BBP test numbers and positivity rate in the year following the introduction of the STI algorithm and the clinical assessment tool.