1. BRIANNA SIERRA
(661) 333 3740 860 Boysen Avenue #1, San Luis Obispo, CA 93405 brisierra@att.net
Education
California Polytechnic State University, San Luis Obispo June 2017
· Chemistry Major; 4th Year; GPA 3.12
· Specialty coursework: Modern Physics, Calculus Series, Quantitative Analysis, Adv. Organic Mechanisms, Adv. Organic Synthesis
Frontier High School ∙ Bakersfield, CA June 2013
· 4.3 GPA; Top 5% of Class
Research Experience
Research and Development Intern ∙ Promega Biosciences Incorporated ∙ San Luis Obispo, CA July 2016 – September 2016
· Synthesized effective target engagement tracers for collaborators to use in drug discovery process
· Worked effectively with Custom Assay Services team by communicating openly and effectively on project standings
· Collaborated with biologists in Madison Headquarters to evaluate kinase tracers
· Analyzed effectiveness of fluorescent dye tracers through cell affinity, permeability, and inhibition tests (IC50)
Student Researcher ∙ California Polytechnic State University ∙ San Luis Obispo, CA September 2015 – Present
· Synthesize small molecules through novel oxidation of carbolines by silver complex
· Develop synthetic protocol for use in building libraries for drug development process
· Cooperate with project team to reach set goals in a timely manner
· Investigated limitations of synthetic pathways
Techniques
· Tedelyne ISCO
· Silica and alumina columns
· Biotage Initiator
· CEM Discover SP
· Schlenk line
· Gel Electrophoresis
· TLC
Software
· Microsoft Suite
· Chem Draw/Chem
BioFinder
· EZ Chrome
· ChemStation
· OpenLab
· Mestranova
Instrumentation
· Preparatory HPLC (Waters)
· HPLC (Agilent)
· LCMS (Waters, Bruker)
· 400 MHZ Bruker NMR
· 300 MHZ Bruker NMR
· IR (Brand)
· GCMS (Brand)
Work Experience
Laboratory Technician ∙ Promega Biosciences Incorporated ∙ San Luis Obispo, CA April 2015 - Present
· Test manufacturing protocols to ensure clarity and validity of syntheses
· Contribute to green chemistry efforts through integration of non-halogenated solvent systems
· Establish structure to reagent storage through electrophile and nucleophile separation
· Create good work flow through organizing lab effectively for chemists
· Maintain efficient work environment by restocking critical solutions and supplies
Secretary for California Polytechnic State University’s American Chemical Society Chapter June 2016 - Present
· Connect with professors and peers through community service and department events
· Keep club running efficiently through organizing socials, keeping meeting minutes, and sending out club emails
Week of Welcome Orientation Leader ∙ California Polytechnic State University, San Luis Obispo April 2014 - September 2014
· Instilled a sense of community and safety in San Luis Obispo with freshman
· Built leadership skills through leading group of incoming freshmen for a week
· Developed communication skills by interacting with group publicly and personally
Tutor ∙ Private September 2012 - May 2013
· Provided support and knowledge to student in mathematics and chemistry
· Helped student build confidence in abilities through positivity and encouragement
Relevant Skills