2. Introduction
• Translation
• Process of conversion from research evidence to
clinical practice
• Phases in research process and time lags
• Translational science
• Description of a Translational Science
Spectrum
• Clinical and Translational Science Awards
(CTSA) Program
3. Introduction—cont’d
• Implementation science
• Study of methods to promote adoption and
integration of evidence-based practices into
routine settings
• Synthesis of research findings into digestible
formats
• Strategy to help implementation of relevant
evidence into clinical practice
• Conceptual frameworks
4. Promoting Action on Research
Implementation in Health Sciences
(PARiHS)
• Multidimensional framework representing
the complexity of the change processes
• Evidence
• Success of implementation processes
dependent on high
• Context
• Environment or setting for health care and
implemented changes
• Influenced by culture, leadership, and
evaluation
5. Promoting Action on Research
Implementation in health Sciences
(PARiHS)
• Facilitation
• Process of enabling the implementation of
evidence into practice
• Areas needing further work
• Conceptual development, empirical testing and
refinement, and reliable measures
• Integrated or iPARiHS
• Recipient construct
• Other changes
6. Consolidation Framework for
Implementation Research
• Goal: advance the field with consistence
structures and customized constructs for
researchers
• Foundation for understanding
implementation
• Guide for formative evaluations
• Organization and promotion of the synthesis
of implementation research findings and
studies
7. Consolidation Framework for
Implementation Research—cont’d
• Five major domains
• Intervention characteristics
• Outer setting
• Inner setting
• Characteristics of individuals
• Process
8. Knowledge-to-Action Framework
• Clarifies key elements involved with moving
knowledge into action
• Focused on concepts of knowledge creation and
the action cycle that leads to implementation of
knowledge
• Funnel representation of knowledge
• Refined and more usable by stakeholders
9. Knowledge-to-Action
Framework—cont’d
• Phases representing the commonalities
within planned action theories
• Knowledge translation and integration into
implementation processes
• Canadian studies on the utilization of the KTA
framework
10. Aims, Ingredients, Mechanism,
Delivery (AIMD)
• International collaboration to develop a
simplified framework
• “Meta-framework”
• “Terminology agnostic”
• Composition of the working research group
11. Aims, Ingredients, Mechanism,
Delivery (AIMD)—cont’d
• Four components
• Intended targets
• Active ingredients
• Causal mechanisms
• Mode of delivery or application
12. Aims, Ingredients, Mechanism,
Delivery (AIMD)—cont’d
• Validation project and further refinement
• Aims, ingredients, mechanism, delivery
• Framework for effective communication
• Guide for the development of intervention
designs and reporting toolkits
• Recommendations for selecting the
appropriate implementation framework
13. Value of Implementation and Team
Science for Sustainable Clinical
Projects
• Team Science: applies conceptual and
methodological approaches to address
complex clinical problems
• Previous lack of training for teams and
interprofessional collaboration
• National Institutes of Health (NIH) and team
science
• Implementation Research Institute (IRI)
14. Value of Implementation and Team
Science for Sustainable Clinical
Projects—cont’d
• Multidisciplinary Translational Team (MTT)
• Team science academic-industry hybrid model
• CTSA support
• Team type trajectories
• Science of Team Science (SciTS)
• Potential for positive impact
• Interprofessional Education Collaborative (IPEC)
Core Competencies
15. Value of Implementation and Team
Science for Sustainable Clinical
Projects—cont’d
• Interview data from five NIH researcher
teams
• Characteristics of an effective team
• Critical element: trust
• Steps to proactively build trust
• Shared mental model (SMM)
• Key contributing characteristics for successful
teamwork
• Not well-defined
16. Value of Implementation and Team
Science for Sustainable Clinical
Projects—cont’d
• Tools to measure teamwork
• TeamSTEPPS Teamwork Attitudes
Questionnaire
• Assesses teamwork attitudes, knowledge, and
skills of learners who have gone through the
TeamSTEPPS curriculum
• Team Climate Inventory
• Scales to measure team climate
17. Implications for Project Planning
and Management
• “Next steps”
• Understanding implementation science models
and tools and strategies for moving evidence
into true practice and sustained improvement
• Common language and terminology
• Incorporation of science of team science
• Assessment tools
• Trust
• Evaluation
18. Summary
• Strategies to address the real-world needs of
patients and the providers who care for
them are the impetus behind Translational,
Implementation, and Team Science in health
care.
19. Summary—cont’d
• National networks such as PCORnet are
actively working to improve health and
health care by fostering faster, less
expensive, and more powerful ways to
conduct observational and experimental
clinical effectiveness research (CER) studies,
utilizing strong partnerships between
patients, clinicians, and health systems via 33
partner networks and a Coordinating Center.
20. Summary—cont’d
• Advances in the fields of Implementation Science and
Team Science are identifying effective strategies for
healthcare providers to take the evidence produced
from these research studies and apply them to
improve the health of patients in their local settings.
• While the challenges of working in multidisciplinary
or interprofessional teams can be great, the benefits
of increased opportunities for new scientific
knowledge, mentorship, and innovation can provide
great rewards that will benefit patients, practice
settings, organizations, and healthcare systems.