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https://www.shutterstock.com/image-illustration/messenger-rna-mrna-strand-3d-rendering-1907619631
Focus on Product, Workflow, End User and
Application, Supply Chain, and Country-
Wise Analysis
Analysis and Forecast: 2021-2031
February 2022
Global Single Cell
RNA Sequencing
Market -
A Global and
Regional Analysis
Table of Content
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BIS Research is a leading market intelligence and technology research company. BIS Research publishes in-
depth market intelligence reports focusing on the market estimations, technology analysis, emerging high-
growth applications, deeply segmented granular country-level market data and other important market
parameters useful in the strategic decision making for senior management. BIS Research provides multi-client
reports, company profiles, databases, and custom research services.
Copyright Β© 2022 BIS Research Inc.
All Rights Reserved. This document contains highly confidential information and is the sole property of BIS
Research. Disclosing, copying, circulating, quoting, or otherwise reproducing any or all contents of this
document is strictly prohibited. Access to this information is provided exclusively for the benefit of the people
or organization concerned. It may not be accessed by or offered, whether for sale or otherwise, to any third
party.
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Table of Content
Executive Summary..........................................................................17
1. Product Definition......................................................................21
1.1 Inclusions and Exclusions..............................................................................21
2. Research Scope and Methodology.............................................22
2.1 Research Scope...............................................................................................22
2.2 Global Single Cell RNA Sequencing Market: Research Methodology ........23
2.3 Primary Data Sources .....................................................................................24
2.4 Secondary Data Sources ................................................................................25
2.5 Market Estimation Model.................................................................................26
2.6 Key Questions Answered in This Report.......................................................28
3. Markets .....................................................................................29
3.1 Market Overview ..............................................................................................30
3.1.1 Introduction of Single Cell RNA Sequencing............................................30
3.1.2 Current Applications of Single Cell RNA Sequencing .............................31
3.1.3 Comparative Analysis of Single Cell RNA Sequencing Technology
and Conventional RNA Sequencing Technology .....................................31
3.1.4 Single Cell RNA Sequencing Market..........................................................32
3.2 Impact of COVID-19 on Global Single Cell RNA Sequencing Market ..........33
3.3 COVID-19 Affecting Supply Chain of Single Cell RNA Sequencing
Market ...............................................................................................................34
3.4 Interruption in Research and Clinical Development and Commercial
Operation..........................................................................................................35
3.4.1 Research and Clinical Development..........................................................35
3.4.2 Commercial Operation and Access............................................................35
3.5 Navigating Crisis Recovery and Looking to the Future ...............................35
3.6 Legal Requirements and Regulations............................................................36
3.6.1 Legal Requirements and Framework in the U.S. ......................................36
3.6.2 Legal Requirements and Regulations in Europe......................................39
3.6.3 Legal Requirements and Framework in the Asia-Pacific.........................41
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3.6.3.1 China ................................................................................................................. 41
3.6.3.2 Japan................................................................................................................. 41
4. Market Dynamics .......................................................................43
4.1 Market Drivers..................................................................................................43
4.1.1 Rising Applications of Single Cell RNA Sequencing in Cancer
Studies and Treatment................................................................................43
4.1.2 Increasing Awareness and Acceptance of Personalized
Diagnostics on a Global Level ...................................................................46
4.1.3 Decreasing Cost of Sequencing.................................................................47
4.1.4 Increasing Government Funding for Healthcare ......................................48
4.2 Business Challenges.......................................................................................49
4.2.1 Computational Challenges in Data Analysis of ScRNA Sequencing......49
4.2.2 High Capital Requirement...........................................................................49
4.2.3 Lack of Infrastructure and Expertise .........................................................50
4.3 Business Opportunities ..................................................................................50
4.3.1 Expansion into Emerging Markets.............................................................50
4.3.2 Expansion into New Research Application...............................................51
4.3.3 Expansion of the Product Portfolio ...........................................................51
5. Competitive Landscape .............................................................52
5.1 New Offerings ..................................................................................................53
5.2 Mergers and Acquisitions...............................................................................53
5.3 Synergistic Activities ......................................................................................54
5.4 Business Expansion and Other Strategies....................................................55
5.5 Market Share Analysis, By Company.............................................................56
6. Global Single Cell RNA Sequencing Market (by Offering)............57
6.1 Global Single Cell RNA Sequencing Market (by Offerings) ), $ Million,
2020-2031..........................................................................................................58
6.1.1 Consumables...............................................................................................59
6.1.2 Instruments..................................................................................................59
7. Global Single Cell RNA Sequencing Market (by Workflow), $
Million, 2020-2031......................................................................61
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7.1 Single Cell Isolation.........................................................................................63
7.1.1 Laser Capture Microscopy (LCM) ..............................................................63
7.1.2 Flow-Activated Cell Sorting (FACS)...........................................................64
7.1.3 Magnetic-Activated Cell Sorting (MACS)...................................................65
7.1.4 Microfluidics ................................................................................................66
7.2 Single Cell Amplification.................................................................................66
7.3 Library Preparation..........................................................................................67
8. Global Single Cell RNA Sequencing Market (by Application), $
Million, 2020-2031......................................................................69
8.1.1 Oncology......................................................................................................70
8.1.2 Immunology .................................................................................................71
8.1.3 Neurology.....................................................................................................72
8.1.4 Embryology..................................................................................................74
8.1.5 Others...........................................................................................................74
9. Global Single Cell RNA Sequencing (by End User), $Million,
2020 and 2031 ...........................................................................76
9.1 Research Organizations..................................................................................77
9.2 Biopharmaceutical Companies ......................................................................78
9.3 Others ...............................................................................................................79
10. Global Single Cell RNA Sequencing Market (by Region) , $
Million, 2020-2031......................................................................81
10.1 North America..................................................................................................84
10.1.1 U.S. ...............................................................................................................85
10.1.2 Canada .........................................................................................................86
10.2 Europe ..............................................................................................................89
10.2.1 U.K. ...............................................................................................................91
10.2.2 Germany.......................................................................................................91
10.2.3 Italy ...............................................................................................................92
10.2.4 Spain.............................................................................................................93
10.2.5 France...........................................................................................................94
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10.2.6 Rest-of-Europe.............................................................................................95
10.3 Asia-Pacific ......................................................................................................98
10.3.1 Japan............................................................................................................99
10.3.2 China ..........................................................................................................100
10.3.3 India............................................................................................................101
10.3.4 South Korea ...............................................................................................102
10.3.5 Australia.....................................................................................................103
10.3.6 Rest-of-Asia-Pacific...................................................................................104
10.4 Rest-of-the-World ..........................................................................................105
11. Company Profiles.....................................................................107
11.1 Company Profiles ..........................................................................................108
11.2 10x Genomics, Inc. ........................................................................................109
11.2.1 Company Overview ...................................................................................109
11.2.2 Role of 10x Genomics, Inc. in Global Single Cell RNA Sequencing
Market.........................................................................................................109
11.2.3 Key Competitors of the Company............................................................110
11.2.4 Financials...................................................................................................111
11.2.5 Key Insights About Financial Health of the Company ...........................113
11.2.6 SWOT Analysis..........................................................................................114
11.3 BGI Group.......................................................................................................115
11.3.1 Company Overview ...................................................................................115
11.3.2 Role of BGI Group in the Global Single Cell RNA Sequencing Market
....................................................................................................................115
11.3.3 Key Competitors of the Company............................................................116
11.3.4 SWOT Analysis..........................................................................................116
11.4 Bio-Rad Laboratories, Inc. ............................................................................117
11.4.2 Company Overview ...................................................................................117
11.4.3 Role of Bio-Rad Laboratories, Inc. in the Global Single Cell RNA
Sequencing Market....................................................................................117
11.4.4 Key Competitors of the Company............................................................118
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11.4.5 Financials...................................................................................................119
11.4.6 Key Insights About Financial Health of the Company ...........................121
11.4.7 SWOT Analysis..........................................................................................122
11.5 Becton, Dickinson and Company (BD) ........................................................123
11.5.1 Company Overview ...................................................................................123
11.5.2 Role of Becton, Dickinson and Company (BD) in the Global Single
Cell RNA Sequencing Market ...................................................................123
11.5.3 Key Competitors of the Company............................................................124
11.5.4 Financials...................................................................................................125
11.5.5 Key Insights About Financial Health of the Company ...........................127
11.5.6 SWOT Analysis..........................................................................................128
11.6 Fluidigm Corporation ....................................................................................129
11.6.1 Company Overview ...................................................................................129
11.6.2 Role of Fluidigm Corporation in the Global Single Cell RNA
Sequencing Market....................................................................................129
11.6.3 Key Competitors of the Company............................................................130
11.6.4 Key Insights About Financial Health of the Company ...........................130
11.6.5 SWOT Analysis..........................................................................................133
11.7 MedGenome ...................................................................................................134
11.7.1 Company Overview ...................................................................................134
11.7.2 Role of MedGenome in the Global Single Cell RNA Sequencing
Market.........................................................................................................134
11.7.3 Key Competitors of the Company............................................................135
11.7.4 SWOT Analysis..........................................................................................136
11.8 NanoString Technologies, Inc. .....................................................................137
11.8.1 Company Overview ...................................................................................137
11.8.2 Role of NanoString Technologies, Inc. in the Global Single Cell RNA
Sequencing Market....................................................................................137
11.8.3 Key Competitors of the Company............................................................138
11.8.4 Key Insights About Financial Health of the Company ...........................138
11.8.5 SWOT Analysis..........................................................................................141
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11.9 Pacific Biosciences of California, Inc. .........................................................142
11.9.1 Company Overview ...................................................................................142
11.9.2 Role of Pacific Biosciences of California, Inc. in the Global Single
Cell RNA Sequencing Market ...................................................................142
11.9.3 Key Competitors of the Company............................................................143
11.9.4 Financials...................................................................................................143
11.9.5 Key Insights About Financial Health of the Company ...........................145
11.9.6 SWOT Analysis..........................................................................................146
11.10 QIAGEN N.V....................................................................................................147
11.10.1 Company Overview.............................................................................147
11.10.2 Role of QIAGEN N.V. in the Global Single Cell RNA Sequencing
Market.........................................................................................................147
11.10.3 Key Competitors of the Company .....................................................148
11.10.4 Financials ............................................................................................148
11.10.5 Key Insights About Financial Health of the Company .....................151
11.10.6 SWOT Analysis....................................................................................152
11.11 PerkinElmer Inc..............................................................................................153
11.11.1 Company Overview.............................................................................153
11.11.2 Role of PerkinElmer Inc. in the Global Single Cell RNA
Sequencing Market....................................................................................153
11.11.3 Key Competitors of the Company .....................................................154
11.11.4 Financials ............................................................................................155
11.11.5 Key Insights About Financial Health of the Company .....................157
11.11.6 SWOT Analysis....................................................................................158
11.12 Takara Bio, Inc. ..............................................................................................159
11.12.1 Company Overview.............................................................................159
11.12.2 Role of Takara Bio, Inc. in the Global Single Cell RNA
Sequencing Market....................................................................................159
11.12.3 Key Competitors of the Company .....................................................159
11.12.4 Key Insights about Financial Health of Company............................160
11.12.5 SWOT Analysis....................................................................................162
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11.13 Thermo Fisher Scientific Inc.........................................................................163
11.13.1 Company Overview.............................................................................163
11.13.2 Role of Thermo Fisher Scientific Inc. in the Global Single Cell
RNA Sequencing Market...........................................................................163
11.13.3 Key Competitors of the Company .....................................................164
11.13.4 Financials ............................................................................................164
11.13.5 Key Insights About Financial Health of the Company .....................166
11.13.6 SWOT Analysis....................................................................................167
Emerging Companies .....................................................................168
11.14 Biomage Ltd...................................................................................................168
11.15 Nucleome Informatics Pvt Ltd. .....................................................................168
11.16 Scailyte ...........................................................................................................169
11.17 Analytical Biosciences Limited. ...................................................................169
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List of Figures
Figure 1: Trends in Single Cell Studies, November 2019-May 2020
Figure 2: Global Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 3: Impact Analysis of Market Drivers and Market Challenges
Figure 4: Share of Key Market Strategies and Developments, January 2017- January 2022
Figure 5: Global Single Cell RNA Sequencing Market (by Region), 2020 and 2031
Figure 6: Global Single Cell RNA Sequencing Market Segmentation
Figure 7: Global Single Cell RNA Sequencing Market Research Methodology
Figure 8: Primary Research
Figure 9: Bottom-Up Approach (Segment-Wise Analysis)
Figure 10: Development History of Single Cell Sequencing
Figure 11: Global Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 12: Positive and Negative Impact of COVID-19 on Single Cell RNA Sequencing Market
Figure 13: Measure to Navigate Crisis Recovery
Figure 14: Global Single Cell RNA Sequencing Market Dynamics
Figure 15: Rising Number of New Cancer Cases (Comparative Analysis of the Cases in 2018 and 2020)
Figure 16: Applications of Single Cell RNA Sequencing in Analysis of Tumour Heterogeneity
Figure 17: Issues Addressed by Single Cell RNA Sequencing in Oncogenomics
Figure 18: Increasing Government Spending for Healthcare, 2017
Figure 19: Share of Key Market Strategies and Developments, January 2017- January 2022
Figure 20: Share of New Offerings (by Company), January 2017-January 2022
Figure 21: Share of Mergers and Acquisitions (by Company), January 2017-January 2022
Figure 22: Share of Synergistic Activities (by Company), January 2017-January 2022
Figure 23: Share of Business Expansion and Other Strategies (by Company), January 2017-January
2022
Figure 24: Market Share Analysis of Global Single Cell RNA Sequencing Market (by Company), 2020
and 2021
Figure 25: Global Single Cell RNA Sequencing (by Offerings), $Million, 2020 and 2031
Figure 26: Global Single Cell RNA Sequencing Consumables Market, $Million, 2020-2031
Figure 27: Global Single Cell RNA Sequencing Instruments Market, $Million, 2020-2031
Figure 28: Global Single Cell RNA Sequencing (by Workflow), $Million, 2020 and 2031
Figure 29: Global Single Cell RNA Sequencing Market (Single Cell Isolation), $ Million, 2020-2031
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Figure 30: Global Single Cell RNA Sequencing Laser Capture Microscopy Market, $Million, 2020-2031
Figure 31: Global Single Cell RNA Sequencing Flow-Activated Cell Sorting Market, $ Million, 2020-2031
Figure 32: Global Single Cell RNA Sequencing Magnetic-Activated Cell Sorting Market, $Million, 2020-
2031
Figure 33: Global Single Cell RNA Sequencing Microfluidics Market, $Million, 2020-2031
Figure 34: Global Single Cell RNA Sequencing Market (Single Cell Amplification), $Million, 2020-2031
Figure 35: Global Single Cell RNA Sequencing Market (Library Preparation), $Million, 2020-2031
Figure 36: Global Single Cell RNA Sequencing (by Application), $Million, 2020 and 2031
Figure 37: Global Single Cell RNA Sequencing Market (Oncology), $Million, 2020-2031
Figure 38: Global Single Cell RNA Sequencing Market (Immunology), $Million, 2020-2031
Figure 39: Global Single Cell RNA Sequencing Market (Neurology), $Million, 2020-2031
Figure 40: Global Single Cell RNA Sequencing Market (Embryology), $Million, 2020-2031
Figure 41: Global Single Cell RNA Sequencing Market (Others), $Million, 2020-2031
Figure 42: Global Single Cell RNA Sequencing (by End-User Type), $Million, 2020 and 2031
Figure 43: Global Single Cell RNA Sequencing Market (Research Organizations), $Million, 2020-2031
Figure 44: Global Single Cell RNA Sequencing Market (Biopharmaceutical Companies), $Million, 2020-
2031
Figure 45: Global Single Cell RNA Sequencing Market (Others), $Million, 2020-2031
Figure 46: Global Single Cell RNA Sequencing Market (by Region), $Million, 2020 and 2031
Figure 47: North America Global Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 48: North America: Market Dynamics
Figure 49: U.S. Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 50: Canada Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 51: Europe Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 52: Europe: Market Dynamics
Figure 53: U.K. Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 54: Germany Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 55: Italy Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 56: Spain Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 57: France Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 58: Rest-of-Europe Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 59: Asia-Pacific Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 60: Asia-Pacific: Market Dynamics
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Figure 61: Japan Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 62: China Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 63: India Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 64: South Korea Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 65: Australia Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 66: Rest-of-Asia-Pacific Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 67: Rest-of-the-World Single Cell RNA Sequencing Market, $Million, 2020-2031
Figure 68: Share of Key Companies Profiled
Figure 69: 10x Genomics, Inc.: Product Portfolio
Figure 70: 10x Genomics, Inc.: Overall Financials, $Million, 2017-2019
Figure 71: 10x Genomics, Inc.: Revenue (by Business Segment), $Million, 2017-2019
Figure 72: 10x Genomics, Inc.: Revenue (by Region), $Million, 2017-2019
Figure 73: : 10x Genomics, Inc.: R&D Expenditure, $Million, 2017-2019
Figure 74: 10x Genomics, Inc.: SWOT Analysis
Figure 75: BGI Group: Product Portfolio
Figure 76: BGI Group: SWOT Analysis
Figure 77: Bio-Rad Laboratories, Inc.: Product Portfolio
Figure 78: Bio-Rad Laboratories, Inc.: Overall Financials, $Million, 2018-2020
Figure 79: Bio-Rad Laboratories, Inc.: Revenue (by Business Segment), $Million, 2018-2020
Figure 80: Bio-Rad Laboratories, Inc.: Revenue (by Region), $Million, 2018-2020
Figure 81: Bio-Rad Laboratories, Inc.: R&D Expenditure, $Million, 2018-2020
Figure 82: Bio-Rad Laboratories, Inc.: SWOT Analysis
Figure 83: Becton, Dickinson and Company (BD): Product Portfolio
Figure 84: Becton, Dickinson and Company (BD): Overall Financials, $Million, 2018-2020
Figure 85: Becton, Dickinson and Company (BD): Revenue (by Segment), $Million, 2018-2020
Figure 86: Becton, Dickinson and Company (BD): Revenue (by Region), $Million, 2018-2020
Figure 87: Becton, Dickinson and Company (BD): R&D Expenditure, $Million, 2018-2020
Figure 88: Becton, Dickinson and Company: SWOT Analysis
Figure 89: Fluidigm Corporation: Overall Financials, $Million, 2016-2018
Figure 90: Fluidigm Corporation: Revenue (by Business Segment), $Million, 2016-2018
Figure 91: Fluidigm Corporation: Revenue (by Region), $Million, 2016-2018
Figure 92: Fluidigm Corporation: R&D Expenditure, $Million, 2016-2018
Figure 93: Fluidigm Corporation: SWOT Analysis
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Figure 94: MedGenome: Product Portfolio
Figure 95: MedGenome: SWOT Analysis
Figure 96: NanoString Technologies, Inc.: Overall Financials, $Million, 2016-2018
Figure 97: NanoString Technologies, Inc.: Revenue (by Business Segment), $Million, 2016-2018
Figure 98: NanoString Technologies, Inc.: Revenue (by Region), $Million, 2016-2018
Figure 99: NanoString Technologies, Inc.: R&D Expenditure, $Million, 2016-2018
Figure 100: NanoString Technologies, Inc.: R&D Expenditure (by Functional Area), $Million, 2016-2018
Figure 101: NanoString Technologies, Inc.: SWOT Analysis
Figure 102: Pacific Biosciences of California, Inc.: Product Portfolio
Figure 103: Pacific Biosciences of California, Inc.: Overall Financials, $Million, 2018-2020
Figure 104: Pacific Biosciences of California, Inc.: Revenue (by Segment), $Million, 2018-2020
Figure 105: Pacific Biosciences of California, Inc.: Revenue (by Region), $Million, 2018-2020
Figure 106: Pacific Biosciences of California, Inc.: R&D Expenditure, $Million, 2018-2020
Figure 107: Pacific Biosciences of California, Inc.: SWOT Analysis
Figure 108: QIAGEN N.V.: Product Portfolio
Figure 109: QIAGEN N.V.: Overall Financials, $Million, 2018-2020
Figure 110: QIAGEN N.V.: Revenue (by Segment), $Million, 2018-2020
Figure 111: QIAGEN N.V.: Revenue (by Region), $Million, 2018-2020
Figure 112: QIAGEN N.V.: R&D Expenditure, $Million, 2018-2020
Figure 113: QIAGEN N.V.: SWOT Analysis
Figure 114: PerkinElmer Inc.: Product Portfolio
Figure 115: PerkinElmer Inc.: Overall Financials, $Million, 2018-2020
Figure 116: PerkinElmer Inc.: Revenue (by Segment), $Million, 2018-2020
Figure 117: PerkinElmer Inc.: Revenue (by Region), $Million, 2018-2020
Figure 118: PerkinElmer Inc.: R&D Expenditure, $Million, 2018-2020
Figure 119: PerkinElmer Inc.: SWOT Analysis
Figure 120: Takara Bio Inc.: Overall Financials, $Million, 2015-2017
Figure 121: Takara Bio, Inc.: Revenue (by Business Segment), $Million, 2015-2017
Figure 122: Takara Bio, Inc.: Revenue (by Region), $Million, 2017
Figure 123: Takara Bio, Inc.: R&D Expenditure, $Million, 2015-2017
Figure 124: Takara Bio Inc.: SWOT Analysis
Figure 125: Thermo Fisher Scientific Inc.: Product Portfolio
Figure 126: Thermo Fisher Scientific Inc.: Overall Financials, $Million, 2018-2020
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Figure 127: Thermo Fisher Scientific Inc.: Revenue (by Business Segment), $Million, 2018–2020
Figure 128: Thermo Fisher Scientific Inc.: Revenue (by Region), $Million, 2018–2020
Figure 129: Thermo Fisher Scientific Inc.: R&D Expenditure, $Million, 2018-2020
Figure 130: Thermo Fisher Scientific Inc.: SWOT Analysis
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List of Tables
Table 1: Difference between Single Cell RNA Sequencing and RNA Sequencing
Table 2: Classification of Directive Groups IVDs
Table 3: Declining Cost of Genome
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Single Cell RNA Sequencing Market.pdf

  • 1. 1 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T https://www.shutterstock.com/image-illustration/messenger-rna-mrna-strand-3d-rendering-1907619631 Focus on Product, Workflow, End User and Application, Supply Chain, and Country- Wise Analysis Analysis and Forecast: 2021-2031 February 2022 Global Single Cell RNA Sequencing Market - A Global and Regional Analysis Table of Content
  • 2. 2 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T BIS Research is a leading market intelligence and technology research company. BIS Research publishes in- depth market intelligence reports focusing on the market estimations, technology analysis, emerging high- growth applications, deeply segmented granular country-level market data and other important market parameters useful in the strategic decision making for senior management. BIS Research provides multi-client reports, company profiles, databases, and custom research services. Copyright Β© 2022 BIS Research Inc. All Rights Reserved. This document contains highly confidential information and is the sole property of BIS Research. Disclosing, copying, circulating, quoting, or otherwise reproducing any or all contents of this document is strictly prohibited. Access to this information is provided exclusively for the benefit of the people or organization concerned. It may not be accessed by or offered, whether for sale or otherwise, to any third party.
  • 3. 3 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T Table of Content Executive Summary..........................................................................17 1. Product Definition......................................................................21 1.1 Inclusions and Exclusions..............................................................................21 2. Research Scope and Methodology.............................................22 2.1 Research Scope...............................................................................................22 2.2 Global Single Cell RNA Sequencing Market: Research Methodology ........23 2.3 Primary Data Sources .....................................................................................24 2.4 Secondary Data Sources ................................................................................25 2.5 Market Estimation Model.................................................................................26 2.6 Key Questions Answered in This Report.......................................................28 3. Markets .....................................................................................29 3.1 Market Overview ..............................................................................................30 3.1.1 Introduction of Single Cell RNA Sequencing............................................30 3.1.2 Current Applications of Single Cell RNA Sequencing .............................31 3.1.3 Comparative Analysis of Single Cell RNA Sequencing Technology and Conventional RNA Sequencing Technology .....................................31 3.1.4 Single Cell RNA Sequencing Market..........................................................32 3.2 Impact of COVID-19 on Global Single Cell RNA Sequencing Market ..........33 3.3 COVID-19 Affecting Supply Chain of Single Cell RNA Sequencing Market ...............................................................................................................34 3.4 Interruption in Research and Clinical Development and Commercial Operation..........................................................................................................35 3.4.1 Research and Clinical Development..........................................................35 3.4.2 Commercial Operation and Access............................................................35 3.5 Navigating Crisis Recovery and Looking to the Future ...............................35 3.6 Legal Requirements and Regulations............................................................36 3.6.1 Legal Requirements and Framework in the U.S. ......................................36 3.6.2 Legal Requirements and Regulations in Europe......................................39 3.6.3 Legal Requirements and Framework in the Asia-Pacific.........................41
  • 4. 4 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T 3.6.3.1 China ................................................................................................................. 41 3.6.3.2 Japan................................................................................................................. 41 4. Market Dynamics .......................................................................43 4.1 Market Drivers..................................................................................................43 4.1.1 Rising Applications of Single Cell RNA Sequencing in Cancer Studies and Treatment................................................................................43 4.1.2 Increasing Awareness and Acceptance of Personalized Diagnostics on a Global Level ...................................................................46 4.1.3 Decreasing Cost of Sequencing.................................................................47 4.1.4 Increasing Government Funding for Healthcare ......................................48 4.2 Business Challenges.......................................................................................49 4.2.1 Computational Challenges in Data Analysis of ScRNA Sequencing......49 4.2.2 High Capital Requirement...........................................................................49 4.2.3 Lack of Infrastructure and Expertise .........................................................50 4.3 Business Opportunities ..................................................................................50 4.3.1 Expansion into Emerging Markets.............................................................50 4.3.2 Expansion into New Research Application...............................................51 4.3.3 Expansion of the Product Portfolio ...........................................................51 5. Competitive Landscape .............................................................52 5.1 New Offerings ..................................................................................................53 5.2 Mergers and Acquisitions...............................................................................53 5.3 Synergistic Activities ......................................................................................54 5.4 Business Expansion and Other Strategies....................................................55 5.5 Market Share Analysis, By Company.............................................................56 6. Global Single Cell RNA Sequencing Market (by Offering)............57 6.1 Global Single Cell RNA Sequencing Market (by Offerings) ), $ Million, 2020-2031..........................................................................................................58 6.1.1 Consumables...............................................................................................59 6.1.2 Instruments..................................................................................................59 7. Global Single Cell RNA Sequencing Market (by Workflow), $ Million, 2020-2031......................................................................61
  • 5. 5 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T 7.1 Single Cell Isolation.........................................................................................63 7.1.1 Laser Capture Microscopy (LCM) ..............................................................63 7.1.2 Flow-Activated Cell Sorting (FACS)...........................................................64 7.1.3 Magnetic-Activated Cell Sorting (MACS)...................................................65 7.1.4 Microfluidics ................................................................................................66 7.2 Single Cell Amplification.................................................................................66 7.3 Library Preparation..........................................................................................67 8. Global Single Cell RNA Sequencing Market (by Application), $ Million, 2020-2031......................................................................69 8.1.1 Oncology......................................................................................................70 8.1.2 Immunology .................................................................................................71 8.1.3 Neurology.....................................................................................................72 8.1.4 Embryology..................................................................................................74 8.1.5 Others...........................................................................................................74 9. Global Single Cell RNA Sequencing (by End User), $Million, 2020 and 2031 ...........................................................................76 9.1 Research Organizations..................................................................................77 9.2 Biopharmaceutical Companies ......................................................................78 9.3 Others ...............................................................................................................79 10. Global Single Cell RNA Sequencing Market (by Region) , $ Million, 2020-2031......................................................................81 10.1 North America..................................................................................................84 10.1.1 U.S. ...............................................................................................................85 10.1.2 Canada .........................................................................................................86 10.2 Europe ..............................................................................................................89 10.2.1 U.K. ...............................................................................................................91 10.2.2 Germany.......................................................................................................91 10.2.3 Italy ...............................................................................................................92 10.2.4 Spain.............................................................................................................93 10.2.5 France...........................................................................................................94
  • 6. 6 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T 10.2.6 Rest-of-Europe.............................................................................................95 10.3 Asia-Pacific ......................................................................................................98 10.3.1 Japan............................................................................................................99 10.3.2 China ..........................................................................................................100 10.3.3 India............................................................................................................101 10.3.4 South Korea ...............................................................................................102 10.3.5 Australia.....................................................................................................103 10.3.6 Rest-of-Asia-Pacific...................................................................................104 10.4 Rest-of-the-World ..........................................................................................105 11. Company Profiles.....................................................................107 11.1 Company Profiles ..........................................................................................108 11.2 10x Genomics, Inc. ........................................................................................109 11.2.1 Company Overview ...................................................................................109 11.2.2 Role of 10x Genomics, Inc. in Global Single Cell RNA Sequencing Market.........................................................................................................109 11.2.3 Key Competitors of the Company............................................................110 11.2.4 Financials...................................................................................................111 11.2.5 Key Insights About Financial Health of the Company ...........................113 11.2.6 SWOT Analysis..........................................................................................114 11.3 BGI Group.......................................................................................................115 11.3.1 Company Overview ...................................................................................115 11.3.2 Role of BGI Group in the Global Single Cell RNA Sequencing Market ....................................................................................................................115 11.3.3 Key Competitors of the Company............................................................116 11.3.4 SWOT Analysis..........................................................................................116 11.4 Bio-Rad Laboratories, Inc. ............................................................................117 11.4.2 Company Overview ...................................................................................117 11.4.3 Role of Bio-Rad Laboratories, Inc. in the Global Single Cell RNA Sequencing Market....................................................................................117 11.4.4 Key Competitors of the Company............................................................118
  • 7. 7 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T 11.4.5 Financials...................................................................................................119 11.4.6 Key Insights About Financial Health of the Company ...........................121 11.4.7 SWOT Analysis..........................................................................................122 11.5 Becton, Dickinson and Company (BD) ........................................................123 11.5.1 Company Overview ...................................................................................123 11.5.2 Role of Becton, Dickinson and Company (BD) in the Global Single Cell RNA Sequencing Market ...................................................................123 11.5.3 Key Competitors of the Company............................................................124 11.5.4 Financials...................................................................................................125 11.5.5 Key Insights About Financial Health of the Company ...........................127 11.5.6 SWOT Analysis..........................................................................................128 11.6 Fluidigm Corporation ....................................................................................129 11.6.1 Company Overview ...................................................................................129 11.6.2 Role of Fluidigm Corporation in the Global Single Cell RNA Sequencing Market....................................................................................129 11.6.3 Key Competitors of the Company............................................................130 11.6.4 Key Insights About Financial Health of the Company ...........................130 11.6.5 SWOT Analysis..........................................................................................133 11.7 MedGenome ...................................................................................................134 11.7.1 Company Overview ...................................................................................134 11.7.2 Role of MedGenome in the Global Single Cell RNA Sequencing Market.........................................................................................................134 11.7.3 Key Competitors of the Company............................................................135 11.7.4 SWOT Analysis..........................................................................................136 11.8 NanoString Technologies, Inc. .....................................................................137 11.8.1 Company Overview ...................................................................................137 11.8.2 Role of NanoString Technologies, Inc. in the Global Single Cell RNA Sequencing Market....................................................................................137 11.8.3 Key Competitors of the Company............................................................138 11.8.4 Key Insights About Financial Health of the Company ...........................138 11.8.5 SWOT Analysis..........................................................................................141
  • 8. 8 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T 11.9 Pacific Biosciences of California, Inc. .........................................................142 11.9.1 Company Overview ...................................................................................142 11.9.2 Role of Pacific Biosciences of California, Inc. in the Global Single Cell RNA Sequencing Market ...................................................................142 11.9.3 Key Competitors of the Company............................................................143 11.9.4 Financials...................................................................................................143 11.9.5 Key Insights About Financial Health of the Company ...........................145 11.9.6 SWOT Analysis..........................................................................................146 11.10 QIAGEN N.V....................................................................................................147 11.10.1 Company Overview.............................................................................147 11.10.2 Role of QIAGEN N.V. in the Global Single Cell RNA Sequencing Market.........................................................................................................147 11.10.3 Key Competitors of the Company .....................................................148 11.10.4 Financials ............................................................................................148 11.10.5 Key Insights About Financial Health of the Company .....................151 11.10.6 SWOT Analysis....................................................................................152 11.11 PerkinElmer Inc..............................................................................................153 11.11.1 Company Overview.............................................................................153 11.11.2 Role of PerkinElmer Inc. in the Global Single Cell RNA Sequencing Market....................................................................................153 11.11.3 Key Competitors of the Company .....................................................154 11.11.4 Financials ............................................................................................155 11.11.5 Key Insights About Financial Health of the Company .....................157 11.11.6 SWOT Analysis....................................................................................158 11.12 Takara Bio, Inc. ..............................................................................................159 11.12.1 Company Overview.............................................................................159 11.12.2 Role of Takara Bio, Inc. in the Global Single Cell RNA Sequencing Market....................................................................................159 11.12.3 Key Competitors of the Company .....................................................159 11.12.4 Key Insights about Financial Health of Company............................160 11.12.5 SWOT Analysis....................................................................................162
  • 9. 9 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T 11.13 Thermo Fisher Scientific Inc.........................................................................163 11.13.1 Company Overview.............................................................................163 11.13.2 Role of Thermo Fisher Scientific Inc. in the Global Single Cell RNA Sequencing Market...........................................................................163 11.13.3 Key Competitors of the Company .....................................................164 11.13.4 Financials ............................................................................................164 11.13.5 Key Insights About Financial Health of the Company .....................166 11.13.6 SWOT Analysis....................................................................................167 Emerging Companies .....................................................................168 11.14 Biomage Ltd...................................................................................................168 11.15 Nucleome Informatics Pvt Ltd. .....................................................................168 11.16 Scailyte ...........................................................................................................169 11.17 Analytical Biosciences Limited. ...................................................................169
  • 10. 10 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T List of Figures Figure 1: Trends in Single Cell Studies, November 2019-May 2020 Figure 2: Global Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 3: Impact Analysis of Market Drivers and Market Challenges Figure 4: Share of Key Market Strategies and Developments, January 2017- January 2022 Figure 5: Global Single Cell RNA Sequencing Market (by Region), 2020 and 2031 Figure 6: Global Single Cell RNA Sequencing Market Segmentation Figure 7: Global Single Cell RNA Sequencing Market Research Methodology Figure 8: Primary Research Figure 9: Bottom-Up Approach (Segment-Wise Analysis) Figure 10: Development History of Single Cell Sequencing Figure 11: Global Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 12: Positive and Negative Impact of COVID-19 on Single Cell RNA Sequencing Market Figure 13: Measure to Navigate Crisis Recovery Figure 14: Global Single Cell RNA Sequencing Market Dynamics Figure 15: Rising Number of New Cancer Cases (Comparative Analysis of the Cases in 2018 and 2020) Figure 16: Applications of Single Cell RNA Sequencing in Analysis of Tumour Heterogeneity Figure 17: Issues Addressed by Single Cell RNA Sequencing in Oncogenomics Figure 18: Increasing Government Spending for Healthcare, 2017 Figure 19: Share of Key Market Strategies and Developments, January 2017- January 2022 Figure 20: Share of New Offerings (by Company), January 2017-January 2022 Figure 21: Share of Mergers and Acquisitions (by Company), January 2017-January 2022 Figure 22: Share of Synergistic Activities (by Company), January 2017-January 2022 Figure 23: Share of Business Expansion and Other Strategies (by Company), January 2017-January 2022 Figure 24: Market Share Analysis of Global Single Cell RNA Sequencing Market (by Company), 2020 and 2021 Figure 25: Global Single Cell RNA Sequencing (by Offerings), $Million, 2020 and 2031 Figure 26: Global Single Cell RNA Sequencing Consumables Market, $Million, 2020-2031 Figure 27: Global Single Cell RNA Sequencing Instruments Market, $Million, 2020-2031 Figure 28: Global Single Cell RNA Sequencing (by Workflow), $Million, 2020 and 2031 Figure 29: Global Single Cell RNA Sequencing Market (Single Cell Isolation), $ Million, 2020-2031
  • 11. 11 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T Figure 30: Global Single Cell RNA Sequencing Laser Capture Microscopy Market, $Million, 2020-2031 Figure 31: Global Single Cell RNA Sequencing Flow-Activated Cell Sorting Market, $ Million, 2020-2031 Figure 32: Global Single Cell RNA Sequencing Magnetic-Activated Cell Sorting Market, $Million, 2020- 2031 Figure 33: Global Single Cell RNA Sequencing Microfluidics Market, $Million, 2020-2031 Figure 34: Global Single Cell RNA Sequencing Market (Single Cell Amplification), $Million, 2020-2031 Figure 35: Global Single Cell RNA Sequencing Market (Library Preparation), $Million, 2020-2031 Figure 36: Global Single Cell RNA Sequencing (by Application), $Million, 2020 and 2031 Figure 37: Global Single Cell RNA Sequencing Market (Oncology), $Million, 2020-2031 Figure 38: Global Single Cell RNA Sequencing Market (Immunology), $Million, 2020-2031 Figure 39: Global Single Cell RNA Sequencing Market (Neurology), $Million, 2020-2031 Figure 40: Global Single Cell RNA Sequencing Market (Embryology), $Million, 2020-2031 Figure 41: Global Single Cell RNA Sequencing Market (Others), $Million, 2020-2031 Figure 42: Global Single Cell RNA Sequencing (by End-User Type), $Million, 2020 and 2031 Figure 43: Global Single Cell RNA Sequencing Market (Research Organizations), $Million, 2020-2031 Figure 44: Global Single Cell RNA Sequencing Market (Biopharmaceutical Companies), $Million, 2020- 2031 Figure 45: Global Single Cell RNA Sequencing Market (Others), $Million, 2020-2031 Figure 46: Global Single Cell RNA Sequencing Market (by Region), $Million, 2020 and 2031 Figure 47: North America Global Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 48: North America: Market Dynamics Figure 49: U.S. Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 50: Canada Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 51: Europe Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 52: Europe: Market Dynamics Figure 53: U.K. Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 54: Germany Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 55: Italy Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 56: Spain Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 57: France Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 58: Rest-of-Europe Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 59: Asia-Pacific Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 60: Asia-Pacific: Market Dynamics
  • 12. 12 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T Figure 61: Japan Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 62: China Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 63: India Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 64: South Korea Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 65: Australia Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 66: Rest-of-Asia-Pacific Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 67: Rest-of-the-World Single Cell RNA Sequencing Market, $Million, 2020-2031 Figure 68: Share of Key Companies Profiled Figure 69: 10x Genomics, Inc.: Product Portfolio Figure 70: 10x Genomics, Inc.: Overall Financials, $Million, 2017-2019 Figure 71: 10x Genomics, Inc.: Revenue (by Business Segment), $Million, 2017-2019 Figure 72: 10x Genomics, Inc.: Revenue (by Region), $Million, 2017-2019 Figure 73: : 10x Genomics, Inc.: R&D Expenditure, $Million, 2017-2019 Figure 74: 10x Genomics, Inc.: SWOT Analysis Figure 75: BGI Group: Product Portfolio Figure 76: BGI Group: SWOT Analysis Figure 77: Bio-Rad Laboratories, Inc.: Product Portfolio Figure 78: Bio-Rad Laboratories, Inc.: Overall Financials, $Million, 2018-2020 Figure 79: Bio-Rad Laboratories, Inc.: Revenue (by Business Segment), $Million, 2018-2020 Figure 80: Bio-Rad Laboratories, Inc.: Revenue (by Region), $Million, 2018-2020 Figure 81: Bio-Rad Laboratories, Inc.: R&D Expenditure, $Million, 2018-2020 Figure 82: Bio-Rad Laboratories, Inc.: SWOT Analysis Figure 83: Becton, Dickinson and Company (BD): Product Portfolio Figure 84: Becton, Dickinson and Company (BD): Overall Financials, $Million, 2018-2020 Figure 85: Becton, Dickinson and Company (BD): Revenue (by Segment), $Million, 2018-2020 Figure 86: Becton, Dickinson and Company (BD): Revenue (by Region), $Million, 2018-2020 Figure 87: Becton, Dickinson and Company (BD): R&D Expenditure, $Million, 2018-2020 Figure 88: Becton, Dickinson and Company: SWOT Analysis Figure 89: Fluidigm Corporation: Overall Financials, $Million, 2016-2018 Figure 90: Fluidigm Corporation: Revenue (by Business Segment), $Million, 2016-2018 Figure 91: Fluidigm Corporation: Revenue (by Region), $Million, 2016-2018 Figure 92: Fluidigm Corporation: R&D Expenditure, $Million, 2016-2018 Figure 93: Fluidigm Corporation: SWOT Analysis
  • 13. 13 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T Figure 94: MedGenome: Product Portfolio Figure 95: MedGenome: SWOT Analysis Figure 96: NanoString Technologies, Inc.: Overall Financials, $Million, 2016-2018 Figure 97: NanoString Technologies, Inc.: Revenue (by Business Segment), $Million, 2016-2018 Figure 98: NanoString Technologies, Inc.: Revenue (by Region), $Million, 2016-2018 Figure 99: NanoString Technologies, Inc.: R&D Expenditure, $Million, 2016-2018 Figure 100: NanoString Technologies, Inc.: R&D Expenditure (by Functional Area), $Million, 2016-2018 Figure 101: NanoString Technologies, Inc.: SWOT Analysis Figure 102: Pacific Biosciences of California, Inc.: Product Portfolio Figure 103: Pacific Biosciences of California, Inc.: Overall Financials, $Million, 2018-2020 Figure 104: Pacific Biosciences of California, Inc.: Revenue (by Segment), $Million, 2018-2020 Figure 105: Pacific Biosciences of California, Inc.: Revenue (by Region), $Million, 2018-2020 Figure 106: Pacific Biosciences of California, Inc.: R&D Expenditure, $Million, 2018-2020 Figure 107: Pacific Biosciences of California, Inc.: SWOT Analysis Figure 108: QIAGEN N.V.: Product Portfolio Figure 109: QIAGEN N.V.: Overall Financials, $Million, 2018-2020 Figure 110: QIAGEN N.V.: Revenue (by Segment), $Million, 2018-2020 Figure 111: QIAGEN N.V.: Revenue (by Region), $Million, 2018-2020 Figure 112: QIAGEN N.V.: R&D Expenditure, $Million, 2018-2020 Figure 113: QIAGEN N.V.: SWOT Analysis Figure 114: PerkinElmer Inc.: Product Portfolio Figure 115: PerkinElmer Inc.: Overall Financials, $Million, 2018-2020 Figure 116: PerkinElmer Inc.: Revenue (by Segment), $Million, 2018-2020 Figure 117: PerkinElmer Inc.: Revenue (by Region), $Million, 2018-2020 Figure 118: PerkinElmer Inc.: R&D Expenditure, $Million, 2018-2020 Figure 119: PerkinElmer Inc.: SWOT Analysis Figure 120: Takara Bio Inc.: Overall Financials, $Million, 2015-2017 Figure 121: Takara Bio, Inc.: Revenue (by Business Segment), $Million, 2015-2017 Figure 122: Takara Bio, Inc.: Revenue (by Region), $Million, 2017 Figure 123: Takara Bio, Inc.: R&D Expenditure, $Million, 2015-2017 Figure 124: Takara Bio Inc.: SWOT Analysis Figure 125: Thermo Fisher Scientific Inc.: Product Portfolio Figure 126: Thermo Fisher Scientific Inc.: Overall Financials, $Million, 2018-2020
  • 14. 14 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T Figure 127: Thermo Fisher Scientific Inc.: Revenue (by Business Segment), $Million, 2018–2020 Figure 128: Thermo Fisher Scientific Inc.: Revenue (by Region), $Million, 2018–2020 Figure 129: Thermo Fisher Scientific Inc.: R&D Expenditure, $Million, 2018-2020 Figure 130: Thermo Fisher Scientific Inc.: SWOT Analysis
  • 15. 15 All rights reserved at BIS Research Inc. G L O B A L S I N G L E C E L L R N A S E Q U E N C I N G M A R K E T List of Tables Table 1: Difference between Single Cell RNA Sequencing and RNA Sequencing Table 2: Classification of Directive Groups IVDs Table 3: Declining Cost of Genome
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