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Global
Neurodegenerative
Disorder Therapeutics
Market
Focus on Product, Mechanism,
Route of Administration, Indication,
Country Data (14 Countries),
and Competitive Landscape:
Analysis and Forecast: 2019-2030
October 2020
TOC
Global Neurodegenerative Disorder Therapeutics Market
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Global Neurodegenerative Disorder Therapeutics Market
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Table of Contents
Executive Summary…………………………………………………………….20
1. Technology Definition.......................................................................................... 41
1.1 Inclusion and Exclusion Criteria................................................................ 41
1.1.1 Inclusions...................................................................................... 41
1.1.2 Exclusions .................................................................................... 42
2. Research Scope.................................................................................................... 43
2.1 Key Questions Answered in the Report.................................................... 45
3. Research Methodology ........................................................................................ 47
3.1 Neurodegenerative Disorder Therapeutics: Research Methodology ..... 47
3.2 Primary Data Sources................................................................................. 48
3.3 Secondary Data Sources............................................................................ 49
3.4 Market Estimation Model............................................................................ 49
3.5 Criteria for Company Profiling................................................................... 52
4. Market Overview................................................................................................... 53
4.1 Neurodegenerative Disorder Therapeutics and Its Clinical Importance 53
4.2 Neurodegenerative Disorder Therapeutics Development and
Commercialization Landscape................................................................... 55
4.3 Global Neurodegenerative Disorder Therapeutics Market and Growth
Potential, 2019-2030.................................................................................... 57
4.4 Pricing and Reimbursement Scenario....................................................... 58
4.5 Impact of Patent Expiry and Entry of Biosimilars on Market .................. 59
4.6 Impact of COVID-19 on Neurodegenerative Disorder Therapeutics
Market........................................................................................................... 61
5. Epidemiology of Neurodegenerative Disorder Therapeutics ........................... 64
6. Patent Landscape................................................................................................. 73
Global Neurodegenerative Disorder Therapeutics Market
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7. Market Dynamics.................................................................................................. 77
7.1 Overview ...................................................................................................... 77
7.2 Impact Analysis........................................................................................... 77
7.3 Drivers.......................................................................................................... 78
7.3.1 Rising Global Prevalence of Neurodegenerative Disorders..... 78
7.3.2 The Increase in Number of Geriatric Populations ..................... 80
7.3.3 Increasing Research Funding in Neurodegenerative Disorders
....................................................................................................... 81
7.3.4 Rising Awareness about Neurodegenerative Disorders........... 82
7.4 Restraints..................................................................................................... 82
7.4.1 High Failure Rate of Neurodegenerative Drugs in Clinical Trials
....................................................................................................... 82
7.4.2 Lack of Effective Drugs and Therapies ...................................... 83
7.5 Opportunities............................................................................................... 84
8. Industry Insights................................................................................................... 85
8.1 Overview ...................................................................................................... 85
8.2 Regulatory Scenario ................................................................................... 85
8.3 Legal Requirements and Frameworks in the U.S..................................... 87
8.3.1 Clinical Trial Authorization.......................................................... 87
8.3.2 Marketing Authorization .............................................................. 88
8.3.3 USFDA Guidelines for BLA Submission .................................... 90
8.3.4 Post-Authorization Regulations.................................................. 91
8.4 Legal Requirements and Frameworks in Europe ..................................... 91
8.4.1 EMA Biologics License Application Process............................. 93
8.4.2 Centralized Procedure ................................................................. 94
8.4.3 Decentralized Procedure ............................................................. 94
8.4.4 Mutual-Recognition Procedure ................................................... 94
8.4.5 National Procedure....................................................................... 95
8.5 Legal Requirements and Frameworks in Asia-Pacific ............................. 95
8.5.1 China ............................................................................................. 95
8.5.2 Japan............................................................................................. 96
Global Neurodegenerative Disorder Therapeutics Market
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8.6 Expedited Regulatory Designations Around the World........................... 97
8.7 Role of Regulatory Bodies and Consortium in Neurodegenerative
Disorder Therapeutics .............................................................................. 100
8.8 Regulatory Guidelines .............................................................................. 100
8.8.1 Terminology Applied in Current Regulatory Guidelines for
Development of Drugs to Treat Neurodegenerative Disorders
..................................................................................................... 100
8.8.2 Actionable Recommendations .................................................. 102
8.8.2.1 EU:.......................................................................................... 102
8.8.2.2 EU:.......................................................................................... 102
8.8.2.3 Both Regions: ......................................................................... 103
8.9 Regulatory Challenges ............................................................................. 103
8.10 Reimbursement and Market Access........................................................ 104
9. Global Neurodegenerative Disorder Therapeutics Market, by Product Type
($Million), 2019-2030........................................................................................... 106
9.1 Commercialized Therapeutics ................................................................. 106
9.1.1 Multiple Sclerosis....................................................................... 106
9.1.1.1 Tecfidera................................................................................. 106
9.1.1.2 Ocrevus................................................................................... 107
9.1.1.3 Gilenya.................................................................................... 107
9.1.1.4 Aubagio................................................................................... 108
9.1.1.5 Interferon (Avonex and Plegridy)............................................. 108
9.1.1.6 Tysabri .................................................................................... 109
9.1.1.7 Rebif........................................................................................ 109
9.1.1.8 Copaxone................................................................................ 110
9.1.1.9 Betaseron................................................................................ 110
9.1.1.10 Lemtrada................................................................................. 111
9.1.1.11 Mavenclad............................................................................... 111
9.1.1.12 Fampyra.................................................................................. 112
9.1.1.13 Ampyra.................................................................................... 112
9.1.1.14 Mayzent .................................................................................. 113
9.1.1.15 Vumerity.................................................................................. 113
Global Neurodegenerative Disorder Therapeutics Market
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9.1.1.16 Others ..................................................................................... 114
9.1.2 Epilepsy....................................................................................... 114
9.1.2.1 Lyrica ...................................................................................... 115
9.1.2.2 Vimpat..................................................................................... 115
9.1.2.3 Onfi ......................................................................................... 116
9.1.2.4 Keppra .................................................................................... 116
9.1.2.5 Sabril....................................................................................... 117
9.1.2.6 Briviact .................................................................................... 117
9.1.2.7 Fycompa ................................................................................. 118
9.1.2.8 Banzel..................................................................................... 118
9.1.2.9 Others ..................................................................................... 119
9.1.3 Alzheimer’s Market..................................................................... 119
9.1.3.1 Ebixa....................................................................................... 120
9.1.3.2 Namenda XR .......................................................................... 120
9.1.3.3 Namzaric................................................................................. 121
9.1.3.4 Galantamine............................................................................ 121
9.1.3.5 Others ..................................................................................... 122
9.1.4 Parkinson’s Disease................................................................... 122
9.1.4.1 Azilect ..................................................................................... 123
9.1.4.2 Neupro .................................................................................... 123
9.1.4.3 Madopar.................................................................................. 124
9.1.4.4 Duopa ..................................................................................... 124
9.1.4.5 Inbrija ...................................................................................... 125
9.1.4.6 Others ..................................................................................... 125
9.1.5 Spinal Muscular Atrophy (SMA)................................................ 126
9.1.5.1 Spinraza.................................................................................. 126
9.1.5.2 Zolgensma .............................................................................. 127
9.1.5.3 Others ..................................................................................... 127
9.1.6 Huntington’s Disease................................................................. 128
9.1.6.1 Austedo................................................................................... 128
9.1.6.2 Xenazine................................................................................. 129
Global Neurodegenerative Disorder Therapeutics Market
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9.1.6.3 Others ..................................................................................... 129
9.2 Pipeline Therapeutics ............................................................................... 130
9.2.1 Multiple Sclerosis....................................................................... 130
9.2.1.1 Zeposia ................................................................................... 130
9.2.1.2 Ponesimod .............................................................................. 130
9.2.1.3 Ofatumumab ........................................................................... 131
9.2.1.4 Ublituximab ............................................................................. 131
9.2.1.5 Ibudilast................................................................................... 132
9.2.1.6 SAR442168............................................................................. 132
9.2.2 Alzheimer’s Disease................................................................... 133
9.2.2.1 Tricaprilin ................................................................................ 133
9.2.2.2 Bryostatin-1............................................................................. 133
9.2.2.3 AGB101 .................................................................................. 134
9.2.2.4 COR388.................................................................................. 134
9.2.2.5 TRx0237 ................................................................................. 135
9.2.2.6 Brexpiprazole .......................................................................... 135
9.2.2.7 Semorinemab.......................................................................... 136
9.2.2.8 Aducanumab........................................................................... 136
9.2.3 Parkinson’s Disease................................................................... 137
9.2.3.1 Eltoprazine.............................................................................. 137
9.2.3.2 Ongentys................................................................................. 137
9.2.3.3 IPX-066................................................................................... 138
9.2.3.4 Xadago.................................................................................... 138
9.2.3.5 Nourianz.................................................................................. 139
9.2.3.6 Opicapone............................................................................... 139
9.2.4 Huntington’s Disease................................................................. 140
9.2.4.1 RG6042/IONIS -HTTrx............................................................ 140
9.2.4.2 WVE-120101........................................................................... 140
9.2.4.3 WVE-120102........................................................................... 141
10. Global Neurodegenerative Disorder Therapeutics Market, by Drug Class
($Million), 2019-2030........................................................................................... 142
Global Neurodegenerative Disorder Therapeutics Market
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10.1 Introduction ............................................................................................... 142
10.2 Immunomodulators................................................................................... 143
10.3 Interferons ................................................................................................. 145
10.4 Dopamine Agonists .................................................................................. 146
10.5 Decarboxylase Inhibitors.......................................................................... 148
10.6 Others......................................................................................................... 149
11. Global Neurodegenerative Disorder Therapeutics Market, by Indication
($Million), 2019-2030........................................................................................... 151
11.1 Overview .................................................................................................... 151
11.2 Multiple Sclerosis...................................................................................... 153
11.3 Epilepsy ..................................................................................................... 154
11.4 Spinal Muscular Atrophy (SMA)............................................................... 155
11.5 Alzheimer’s Disease ................................................................................. 157
11.6 Parkinson’s Disease ................................................................................. 158
11.7 Huntington’s Disease................................................................................ 159
11.8 Other Neurological Disorders .................................................................. 161
12. Global Neurodegenerative Disorder Therapeutics Market, by Route of Drug
Administration ($Million), 2019-2030 ................................................................ 162
12.1 Introduction ............................................................................................... 162
12.2 Oral............................................................................................................. 163
12.3 Injectable.................................................................................................... 164
12.4 Enteral........................................................................................................ 165
12.5 Transdermal............................................................................................... 166
12.6 Others......................................................................................................... 166
13. Global Neurodegenerative Disorder Therapeutics Market, by Region
($Million), 2019-2030........................................................................................... 168
13.1 Overview .................................................................................................... 168
13.2 North America ........................................................................................... 170
13.2.1 U.S. .............................................................................................. 173
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13.2.1.1 U.S. Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 175
13.2.2 Canada ........................................................................................ 176
13.2.2.1 Canada Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 177
13.3 Europe........................................................................................................ 178
13.3.1 Germany...................................................................................... 181
13.3.1.1 Germany Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 182
13.3.2 U.K. .............................................................................................. 183
13.3.2.1 U.K. Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 184
13.3.3 France.......................................................................................... 185
13.3.3.1 France Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 186
13.3.4 Italy .............................................................................................. 187
13.3.4.1 Italy Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 188
13.3.5 Spain............................................................................................ 189
13.3.5.1 Spain Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 190
13.3.6 Rest-of-Europe ........................................................................... 191
13.3.6.1 RoE Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 192
13.4 Asia-Pacific................................................................................................ 193
13.4.1 China ........................................................................................... 196
13.4.1.1 China Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 198
13.4.2 Japan........................................................................................... 199
13.4.2.1 Japan Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 201
13.4.3 India............................................................................................. 201
13.4.3.1 India Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 203
Global Neurodegenerative Disorder Therapeutics Market
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13.4.4 South Korea................................................................................ 204
13.4.4.1 South Korea Neurodegenerative Disorder Therapeutics Market
(by Indication), 2019-2030 ...................................................... 205
13.4.5 Australia...................................................................................... 206
13.4.5.1 Australia Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 207
13.4.6 Rest-of-APAC.............................................................................. 208
13.4.6.1 RoAPAC Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 209
13.5 Latin America ............................................................................................ 210
13.5.1 Brazil............................................................................................ 213
13.5.1.1 Brazil Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 214
13.5.2 Mexico ......................................................................................... 215
13.5.2.1 Mexico Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 216
13.5.3 Rest-of-Latin America ................................................................ 217
13.5.3.1 RoLATAM Neurodegenerative Disorder Therapeutics Market (by
Indication), 2019-2030 ............................................................ 218
13.6 Rest-of-the-World...................................................................................... 219
14. Competitive Landscape ..................................................................................... 220
14.1 Key Developments and Strategies .......................................................... 220
14.1.1 Regulatory and Legal Developments........................................ 222
14.1.2 Partnerships, Alliances, and Business Expansions................ 222
14.1.3 M&A Activities ............................................................................ 223
14.1.4 Funding Activities ...................................................................... 224
14.2 Market Share Analysis.............................................................................. 225
15. Company Profiles............................................................................................... 227
15.1 Overview .................................................................................................... 227
15.2 AbbVie Inc.................................................................................................. 228
15.2.1 Company Overview .................................................................... 228
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15.2.2 Role of AbbVie Inc. in Global Neurodegenerative Disorder
Therapeutics Market .................................................................. 228
15.2.3 Financials.................................................................................... 231
15.2.4 Key Insights about Financial Health of the Company............. 233
15.2.5 SWOT Analysis........................................................................... 234
15.3 Bayer AG.................................................................................................... 235
15.3.1 Company Overview .................................................................... 235
15.3.2 Role of Bayer AG in Global Neurodegenerative Disorder
Therapeutics Market .................................................................. 235
15.3.3 Financials.................................................................................... 236
15.3.4 Key Insight about Financial Health of the Company............... 238
15.3.5 SWOT Analysis........................................................................... 239
15.4 Biogen Inc.................................................................................................. 240
15.4.1 Company Overview .................................................................... 240
15.4.2 Role of Biogen Inc. in Global Neurodegenerative Disorder
Therapeutics Market .................................................................. 240
15.4.3 Financials.................................................................................... 244
15.4.4 Key Insights about Financial Health of the Company............. 246
15.4.5 SWOT Analysis........................................................................... 247
15.5 Bristol-Myers Squibb Company............................................................... 248
15.5.1 Company Overview .................................................................... 248
15.5.2 Role of Bristol Myers Squibb Company in Global
Neurodegenerative Disorder Therapeutics Market ................. 248
15.5.3 Financials.................................................................................... 250
15.5.4 Key Insights About Financial Health of the Company ............ 251
15.5.5 SWOT Analysis........................................................................... 252
15.6 C. H. Boehringer Sohn AG & Co. KG....................................................... 253
15.6.1 Company Overview .................................................................... 253
15.6.2 Role of C. H. Boehringer Sohn AG & Co. KG in Global
Neurodegenerative Disorder Therapeutics Market ................. 253
15.6.3 Financials.................................................................................... 255
15.6.4 Key Insight about Financial Health of the Company............... 257
15.6.5 SWOT Analysis........................................................................... 258
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15.7 Eisai Inc...................................................................................................... 259
15.7.1 Company Overview .................................................................... 259
15.7.2 Role of Eisai Inc. in Global Neurodegenerative Disorder
Therapeutics Market .................................................................. 259
15.7.3 Financials.................................................................................... 262
15.7.4 Key Insight about Financial Health of the Company............... 265
15.7.5 SWOT Analysis........................................................................... 266
15.8 F. Hoffmann-La Roche Ltd. ...................................................................... 267
15.8.1 Company Overview .................................................................... 267
15.8.2 Role of F. Hoffmann-La Roche Ltd. in Global Neurodegenerative
Disorder Therapeutics Market................................................... 267
15.8.3 Financials.................................................................................... 270
15.8.4 Key Insights About Financial Health of the Company ............ 272
15.8.5 SWOT Analysis........................................................................... 273
15.9 GlaxoSmithKline plc ................................................................................. 274
15.9.1 Company Overview .................................................................... 274
15.9.2 Role of GlaxoSmithKline plc in Global Neurodegenerative
Disorder Therapeutics Market................................................... 274
15.9.3 Financials.................................................................................... 276
15.9.4 Key Insights about Financial Health of the Company............. 279
15.9.5 SWOT Analysis........................................................................... 280
15.10H. Lundbeck A/S........................................................................................ 281
15.10.1 Company Overview .................................................................... 281
15.10.2 Role of H. Lundbeck A/S in Global Neurodegenerative Disorder
Therapeutics Market .................................................................. 281
15.10.3 Financials.................................................................................... 283
15.10.4 Key Insight about Financial Health of the Company............... 285
15.10.5 SWOT Analysis........................................................................... 286
15.11Merck KGaA............................................................................................... 287
15.11.1 Company Overview .................................................................... 287
15.11.2 Role of Merck KGaA in Global Neurodegenerative Disorder
Therapeutics Market .................................................................. 287
15.11.3 Financials.................................................................................... 289
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15.11.4 Key Insights About Financial Health of the Company ............ 291
15.11.5 SWOT Analysis........................................................................... 292
15.12Novartis AG ............................................................................................... 293
15.12.1 Company Overview .................................................................... 293
15.12.2 Role of Novartis AG in Global Neurodegenerative Disorder
Therapeutics Market .................................................................. 293
15.12.3 Financials.................................................................................... 295
15.12.4 Key Insights About Financial Health of the Company ............ 297
15.12.5 SWOT Analysis........................................................................... 298
15.13Pfizer Inc. ................................................................................................... 299
15.13.1 Company Overview .................................................................... 299
15.13.2 Role of Pfizer Inc. in Global Neurodegenerative Disorder
Therapeutics Market .................................................................. 299
15.13.3 Financials.................................................................................... 301
15.13.4 Key Insights About Financial Health of the Company ............ 304
15.13.5 SWOT Analysis........................................................................... 305
15.14Sanofi S.A. ................................................................................................. 306
15.14.1 Company Overview .................................................................... 306
15.14.2 Role of Sanofi SA in Global Neurodegenerative Disorder
Therapeutics Market .................................................................. 306
15.14.3 Financials.................................................................................... 309
15.14.4 Key Insights About Financial Health of the Company ............ 311
15.14.5 SWOT Analysis........................................................................... 312
15.15Teva Pharmaceutical Industries Ltd........................................................ 313
15.15.1 Company Overview .................................................................... 313
15.15.2 Role of Teva Pharmaceutical Industries Ltd. in Global
Neurodegenerative Disorder Therapeutics Market ................. 313
15.15.3 Financials.................................................................................... 315
15.15.4 Key Insight about Financial Health of the Company............... 317
15.15.5 SWOT Analysis........................................................................... 318
15.16UCB Pharma SA. ....................................................................................... 319
15.16.1 Company Overview .................................................................... 319
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15.16.2 Role of UCB Pharma SA in Global Neurodegenerative Disorder
Therapeutics Market .................................................................. 319
15.16.3 Financials.................................................................................... 321
15.16.4 Key Insight about Financial Health of the Company............... 323
15.16.5 SWOT Analysis........................................................................... 324
Global Neurodegenerative Disorder Therapeutics Market
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List of Figures
Figure 1: Global Total Burden of Diseases by Cause ......................................................................30
Figure 2: Global Geriatric Population by Age...................................................................................31
Figure 3: Global Neurodegenerative Disorder Therapeutics Market................................................32
Figure 4: Impact Analysis.................................................................................................................33
Figure 5: Share of Key Developments and Strategies, June 2015-June 2020.................................35
Figure 6: Global Neurodegenerative Disorder Therapeutics Market (by Drug Class), 2019 and 2030
.........................................................................................................................................................36
Figure 7: Global Neurodegenerative Disorder Therapeutics Market (by Indication), 2019 and 2030
.........................................................................................................................................................37
Figure 8: Global Neurodegenerative Disorder Therapeutics Market (by Route of Administraton), 2019
and 2030..........................................................................................................................................38
Figure 9: Global Neurodegenerative Disorder Therapeutics Market (by Region), 2019-2030..........39
Figure 2.1: Global Neurodegenerative Disorder Therapeutics Market Segmentation......................43
Figure 3.1: Global Neurodegenerative Disorder Therapeutic Market Methodology .........................46
Figure 3.2: Primary Research Methodology.....................................................................................47
Figure 3.3: Bottom-Up Approach (Segment-Wise Analysis) ............................................................49
Figure 3.4: Top-Down Approach (Segment-Wise Analysis).............................................................49
Figure 4.1: Neurodegenerative Disorder Therapeutics Clinical Trial Landscape..............................53
Figure 4.2: Global Neurodegenerative Disorder Market 2019-2030.................................................57
Figure 4.3: Patent Expiry of Neurodegenerative Disorder Therapies...............................................59
Figure 4.4: Most Impacted Practices in the Treatment of Neurodegenerative Disorders .................61
Figure 5.1: Prevalence of Neurodegenerative Disorders in the U.S. (Total Population)...................64
Figure 5.2: Prevalence of Alzheimer’s Disease in the U.S. (Total Population).................................65
Figure 5.3: Prevalence of Epilepsy in the U.S. (Total Population)....................................................65
Figure 5.4: Prevalence of Parkinson’s Disease in the U.S. (Total Population).................................66
Figure 5.5: Prevalence of Multiple Sclerosis in the U.S. (Total Population)......................................66
Figure 5.6: Prevalence of Spinal Muscular Atrophy (SMA) in the U.S. (Total Population)................67
Figure 5.7: Prevalence of Huntington's Disease in the U.S. (Total Population)................................67
Figure 5.8: Target Population of Epilepsy in the U.S........................................................................69
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Figure 5.9: Target Population of Alzheimer’s Disease in the U.S.....................................................69
Figure 5.10: Target Population of Multiple Sclerosis in the U.S. ......................................................70
Figure 5.11: Target Population of Parkinson’s Disease in the U.S...................................................70
Figure 5.12: Target Population of Huntington's Disease in the U.S..................................................71
Figure 6.1: Number of Patents Filed, Neurodegenerative Disorder Therapeutics/Drugs, January 2015-
December 2019...............................................................................................................................72
Figure 6.2: Number of Patents Filed, Multiple Sclerosis Therapeutics/Drugs, January 2015-December
2019.................................................................................................................................................73
Figure 6.3: Number of Patents Filed, Alzheimer’s Disease Therapeutics/Drugs, January 2015-
December 2019...............................................................................................................................74
Figure 6.4: Percentage of Patents Filed, By Patent Office, January 2015-December 2019.............75
Figure 7.1: Impact Analysis..............................................................................................................77
Figure 7.2: Global Total Burden of Diseases by Cause ...................................................................78
Figure 7.3: Global Geriatric Population by Age................................................................................80
Figure 8.1: Steps for Obtaining Marketing Authorization..................................................................88
Figure 8.2: USFDA Review Timeline ...............................................................................................89
Figure 8.3: EMA Review Timeline....................................................................................................92
Figure 9.1: Global Neurodegenerative Disorder Therapeutics Market (Tecfidera - Product Revenue),
2019-2030 .....................................................................................................................................105
Figure 9.2: Global Neurodegenerative Disorder Therapeutics Market (Ocrevus – Product Revenue),
2019-2030 .....................................................................................................................................106
Figure 9.3: Global Neurodegenerative Disorder Therapeutics Market (Gilenya – Product Revenue),
2019-2030 .....................................................................................................................................106
Figure 9.4: Global Neurodegenerative Disorder Therapeutics Market (Aubagio – Product Revenue),
2019-2030 .....................................................................................................................................107
Figure 9.5: Global Neurodegenerative Disorder Therapeutics Market (Interferon (Avonex and
Plegridy) – Product Revenue), 2019-2030.....................................................................................107
Figure 9.6: Global Neurodegenerative Disorder Therapeutics Market (Tysabri – Product Revenue),
2019-2030 .....................................................................................................................................108
Figure 9.7: Global Neurodegenerative Disorder Therapeutics Market (Rebif – Product Revenue),
2019-2030 .....................................................................................................................................108
Global Neurodegenerative Disorder Therapeutics Market
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Figure 9.8: Global Neurodegenerative Disorder Therapeutics Market (Copaxone – Product Revenue),
2019-2030 .....................................................................................................................................109
Figure 9.9: Global Neurodegenerative Disorder Therapeutics Market (Betaseron – Product Revenue),
2019-2030 .....................................................................................................................................109
Figure 9.10: Global Neurodegenerative Disorder Therapeutics Market (Lemtrada – Product
Revenue), 2019-2030....................................................................................................................110
Figure 9.11: Global Neurodegenerative Disorder Therapeutics Market (Mavenclad – Product
Revenue), 2019-2030....................................................................................................................110
Figure 9.12: Global Neurodegenerative Disorder Therapeutics Market (Fampyra – Product Revenue),
2019-2030 .....................................................................................................................................111
Figure 9.13: Global Neurodegenerative Disorder Therapeutics Market (Ampyra – Product Revenue),
2019-2030 .....................................................................................................................................111
Figure 9.14: Global Neurodegenerative Disorder Therapeutics Market (Mayzent – Product Revenue),
2019-2030 .....................................................................................................................................112
Figure 9.15: Global Neurodegenerative Disorder Therapeutics Market (Vumerity – Product Revenue),
2019-2030 .....................................................................................................................................112
Figure 9.16: Global Neurodegenerative Disorder Therapeutics Market (Others – Product Revenue),
2019-2030 .....................................................................................................................................113
Figure 9.17: Global Neurodegenerative Disorder Therapeutics Market (Lyrica – Product Revenue),
2019-2030 .....................................................................................................................................114
Figure 9.18: Global Neurodegenerative Disorder Therapeutics Market (Vimpat – Product Revenue),
2019-2030 .....................................................................................................................................114
Figure 9.19: Global Neurodegenerative Disorder Therapeutics Market (Onfi – Product Revenue),
2019-2030 .....................................................................................................................................115
Figure 9.20: Global Neurodegenerative Disorder Therapeutics Market (Keppra – Product Revenue),
2019-2030 .....................................................................................................................................115
Figure 9.21: Global Neurodegenerative Disorder Therapeutics Market (Sabril – Product Revenue),
2019-2030 .....................................................................................................................................116
Figure 9.22: Global Neurodegenerative Disorder Therapeutics Market (Briviact – Product Revenue),
2019-2030 .....................................................................................................................................116
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Figure 9.23: Global Neurodegenerative Disorder Therapeutics Market (Fycompa – Product
Revenue), 2019-2030....................................................................................................................117
Figure 9.24: Global Neurodegenerative Disorder Therapeutics Market (Banzel – Product Revenue),
2019-2030 .....................................................................................................................................117
Figure 9.25: Global Neurodegenerative Disorder Therapeutics Market (Others – Product Revenue),
2019-2030 .....................................................................................................................................118
Figure 9.26: Global Neurodegenerative Disorder Therapeutics Market (Ebixa – Product Revenue),
2019-2030 .....................................................................................................................................119
Figure 9.27: Global Neurodegenerative Disorder Therapeutics Market (Namenda XR – Product
Revenue), 2019-2030....................................................................................................................119
Figure 9.28: Global Neurodegenerative Disorder Therapeutics Market (Namzaric – Product
Revenue), 2019-2030....................................................................................................................120
Figure 9.29: Global Neurodegenerative Disorder Therapeutics Market (Galantamine – Product
Revenue), 2019-2030....................................................................................................................120
Figure 9.30: Global Neurodegenerative Disorder Therapeutics Market (Others – Product Revenue),
2019-2030 .....................................................................................................................................121
Figure 9.31: Global Neurodegenerative Disorder Therapeutics Market (Azilect – Product Revenue),
2019-2030 .....................................................................................................................................122
Figure 9.32: Global Neurodegenerative Disorder Therapeutics Market (Neupro – Product Revenue),
2019-2030 .....................................................................................................................................122
Figure 9.33: Global Neurodegenerative Disorder Therapeutics Market (Madopar – Product Revenue),
2019-2030 .....................................................................................................................................123
Figure 9.34: Global Neurodegenerative Disorder Therapeutics Market (Duopa – Product Revenue),
2019-2030 .....................................................................................................................................123
Figure 9.35: Global Neurodegenerative Disorder Therapeutics Market (Inbrija – Product Revenue),
2019-2030 .....................................................................................................................................124
Figure 9.36: Global Neurodegenerative Disorder Therapeutics Market (Others – Product Revenue),
2019-2030 .....................................................................................................................................124
Figure 9.37: Global Neurodegenerative Disorder Therapeutics Market (Spinraza – Product Revenue),
2019-2030 .....................................................................................................................................125
Global Neurodegenerative Disorder Therapeutics Market
All rights reserved at BIS Research 19
Figure 9.38: Global Neurodegenerative Disorder Therapeutics Market (Zolgensma – Product
Revenue), 2019-2030....................................................................................................................126
Figure 9.39: Global Neurodegenerative Disorder Therapeutics Market (Others – Product Revenue),
2019-2030 .....................................................................................................................................126
Figure 9.40: Global Neurodegenerative Disorder Therapeutics Market (Austedo – Product
Revenue),2019-2030.....................................................................................................................127
Figure 9.41: Global Neurodegenerative Disorder Therapeutics Market (Xenazine – Product
Revenue),2019-2030.....................................................................................................................128
Figure 9.42: Global Neurodegenerative Disorder Therapeutics Market (Others – Product Revenue),
2019-2030 .....................................................................................................................................128
Figure 9.43: Global Neurodegenerative Disorder Therapeutics Market (Zeposia Expected Launch -
2020), 2019-2030 ..........................................................................................................................129
Figure 9.44: Global Neurodegenerative Disorder Therapeutics Market (Ponesimod Expected Launch
- 2020), 2019-2030 ........................................................................................................................129
Figure 9.45: Global Neurodegenerative Disorder Therapeutics Market (Ofatumumab Expected
Launch 2021), 2019-2030..............................................................................................................130
Figure 9.46: Global Neurodegenerative Disorder Therapeutics Market (Ublituximab Expected Launch
- 2021), 2019-2030 ........................................................................................................................130
Figure 9.47: Global Neurodegenerative Disorder Therapeutics Market (Ibudilast Expected Launch -
2022), 2019-2030 ..........................................................................................................................131
Figure 9.48: Global Neurodegenerative Disorder Therapeutics Market (SAR442168 Expected Launch
- 2026), 2019-2030 ........................................................................................................................131
Figure 9.49: Global Neurodegenerative Disorder Therapeutics Market (Tricaprilin Expected Launch -
2023), 2019-2030 ..........................................................................................................................132
Figure 9.50: Global Neurodegenerative Disorder Therapeutics Market (Bryostatin-1 Expected Launch
- 2025), 2019-2030 ........................................................................................................................132
Figure 9.51: Global Neurodegenerative Disorder Therapeutics Market (AGB101 Expected Launch -
2025), 2019-2030 ..........................................................................................................................133
Figure 9.52: Global Neurodegenerative Disorder Therapeutics Market (COR388 Expected Launch -
2023), 2019-2030 ..........................................................................................................................133
Global Neurodegenerative Disorder Therapeutics Market
All rights reserved at BIS Research 20
Figure 9.53: Global Neurodegenerative Disorder Therapeutics Market (TRx0237 Expected Launch -
2024), 2019-2030 ..........................................................................................................................134
Figure 9.54: Global Neurodegenerative Disorder Therapeutics Market (Brexpiprazole Expected
Launch - 2023), 2019-2030............................................................................................................134
Figure 9.55: Global Neurodegenerative Disorder Therapeutics Market (Semorinemab Expected
Launch - 2024), 2019-2030............................................................................................................135
Figure 9.56: Global Neurodegenerative Disorder Therapeutics Market (Aducanumab Expected
Launch - 2020), 2019-2030............................................................................................................135
Figure 9.57: Global Neurodegenerative Disorder Therapeutics Market (Eltoprazine Expected Launch
- 2020), 2019-2030 ........................................................................................................................136
Figure 9.58: Global Neurodegenerative Disorder Therapeutics Market (Ongentys Expected Launch -
2020), 2019-2030 ..........................................................................................................................136
Figure 9.59: Global Neurodegenerative Disorder Therapeutics Market (IPX-066 Expected Launch -
2020), 2019-2030 ..........................................................................................................................137
Figure 9.60: Global Neurodegenerative Disorder Therapeutics Market (Xadago Expected Launch -
2020), 2019-2030 ..........................................................................................................................137
Figure 9.61: Global Neurodegenerative Disorder Therapeutics Market (Nourianz Expected Launch -
2020), 2019-2030 ..........................................................................................................................138
Figure 9.62: Global Neurodegenerative Disorder Therapeutics Market (Opicapone Expected Launch
- 2020), 2019-2030 ........................................................................................................................138
Figure 9.63: Global Neurodegenerative Disorder Therapeutics Market (RG6042/IONIS -HTTrx
Expected Launch - 2021), 2019-2030............................................................................................139
Figure 9.64: Global Neurodegenerative Disorder Therapeutics Market (WVE-120101 Expected
Launch - 2022), 2019-2030............................................................................................................139
Figure 9.65: Global Neurodegenerative Disorder Therapeutics Market (WVE-120102 Expected
Launch - 2022), 2019-2030............................................................................................................140
Figure 10.1: Revenue Contribution of Different Segments, 2019 and 2030...................................142
Figure 10.2: Global Neurodegenerative Disorder Therapeutics Market (by Immunomodulators), 2019-
2030...............................................................................................................................................143
Figure 10.3: Global Neurodegenerative Disorder Therapeutics Market (by Interferons), 2019-2030
.......................................................................................................................................................145
Global Neurodegenerative Disorder Therapeutics Market
All rights reserved at BIS Research 21
Figure 10.4: Global Neurodegenerative Disorder Therapeutics Market (by Dopamine agonists), 2019-
2030...............................................................................................................................................146
Figure 10.5: Global Neurodegenerative Disorder Therapeutics Market (by Decarboxylase Inhibitors),
2019-2030 .....................................................................................................................................147
Figure 10.6: Global Neurodegenerative Disorder Therapeutics Market (by Others), 2019-2030 ...149
Figure 11.1: Global Neurodegenerative Disorder Therapeutics Market, by Indication ...................151
Figure 11.2: Global Neurodegenerative Disorder Therapeutics Market (by Indication), 2020 and 2030
.......................................................................................................................................................151
Figure 11.3: Global Neurodegenerative Disorder Therapeutics Market (by Multiple Sclerosis), 2019-
2030...............................................................................................................................................152
Figure 11.4: Global Neurodegenerative Disorder Therapeutics Market (by Epilepsy), 2019-2030.154
Figure 11.5: Global Neurodegenerative Disorder Therapeutics Market (by Spinal Muscular Atrophy),
2019-2030 .....................................................................................................................................155
Figure 11.6: Global Neurodegenerative Disorder Therapeutics Market (by Alzheimer’s disease),
2019-2030 .....................................................................................................................................156
Figure 11.7: Global Neurodegenerative Disorder Therapeutics Market (by Parkinson’s disease),
2019-2030 .....................................................................................................................................158
Figure 11.8: Global Neurodegenerative Disorder Therapeutics Market (by Huntington’s disease),
2019-2030 .....................................................................................................................................159
Figure 11.9: Global Neurodegenerative Disorder Therapeutics Market (by Other Neurological
Disorders), 2019-2030...................................................................................................................160
Figure 12.1: Revenue Contribution of Different Segments, 2020 and 2030...................................161
Figure 12.2: Global Neurodegenerative Disorder Therapeutics Market (by Oral), 2019-2030 .......162
Figure 12.3: Global Neurodegenerative Disorder Therapeutics Market (by Injectable), 2019-2030
.......................................................................................................................................................163
Figure 12.4: Global Neurodegenerative Disorder Therapeutics Market (by Enteral), 2019-2030..164
Figure 12.5: Global Neurodegenerative Disorder Therapeutics Market (by Transdermal), 2019-2030
.......................................................................................................................................................165
Figure 12.6: Global Neurodegenerative Disorder Therapeutics Market (by Other RoA), 2019-2030
.......................................................................................................................................................166
Figure 13.1: Global Neurodegenerative Disorder Therapeutics Market (by Region)......................167
Global Neurodegenerative Disorder Therapeutics Market
All rights reserved at BIS Research 22
Figure 13.2: Global Neurodegenerative Disorder Therapeutics Market (by Region), 2019-2030..168
Figure 13.3: North America Neurodegenerative Disorder Therapeutics Market, 2019-2030..........169
Figure 13.4: North America: Market Dynamics ..............................................................................170
Figure 13.5: Revenue Contributions of Different Countries in North America, 2019 and 2030......171
Figure 13.6: U.S. Neurodegenerative Disorder Therapeutics Market, 2019-2030 .........................173
Figure 13.7: U.S. Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ..174
Figure 13.8: Canada Neurodegenerative Disorder Therapeutics Market, 2019-2030....................175
Figure 13.9: Canada Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030
.......................................................................................................................................................176
Figure 13.10: Europe Neurodegenerative Disorder Therapeutics Market, 2019-2030...................178
Figure 13.11: Europe: Market Dynamics........................................................................................178
Figure 13.12: Revenue Contributions Different Countries in Europe, 2019 and 2030....................179
Figure 13.13: Germany Neurodegenerative Disorder Therapeutics Market, 2019-2030................180
Figure 13.14: Germany Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030
.......................................................................................................................................................181
Figure 13.15: U.K. Neurodegenerative Disorder Therapeutics Market, 2019-2030 .......................182
Figure 13.16: U.K. Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 183
Figure 13.17: France Neurodegenerative Disorder Therapeutics Market, 2019-2030 ...................184
Figure 13.18: France Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030
.......................................................................................................................................................185
Figure 13.19: Italy Neurodegenerative Disorder Therapeutics Market, 2019-2030........................186
Figure 13.20: Italy Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030.187
Figure 13.21: Spain Neurodegenerative Disorder Therapeutics Market, 2019-2030 .....................188
Figure 13.22: Spain Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030
.......................................................................................................................................................189
Figure 13.23: Rest-of-Europe Neurodegenerative Disorder Therapeutics Market, 2019-2030 ......190
Figure 13.24: RoE Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 191
Figure 13.25: Asia-Pacific Neurodegenerative Disorder Therapeutics Market, 2019-2030............192
Figure 13.26: APAC: Market Dynamics .........................................................................................193
Figure 13.27: Revenue Contributions Different Countries in Asia-Pacific, 2019 and 2030.............194
Figure 13.28: China Neurodegenerative Disorder Therapeutics Market, 2019-2030.....................196
Global Neurodegenerative Disorder Therapeutics Market
All rights reserved at BIS Research 23
Figure 13.29: China Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030
.......................................................................................................................................................197
Figure 13.30: Japan Neurodegenerative Disorder Therapeutics Market, 2019-2030.....................198
Figure 13.31: Japan Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030
.......................................................................................................................................................200
Figure 13.32: India Neurodegenerative Disorder Therapeutics Market, 2019-2030.......................201
Figure 13.33: India Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030202
Figure 13.34: South Korea Neurodegenerative Disorder Therapeutics Market, 2019-2030...........203
Figure 13.35: South Korea Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-
2030...............................................................................................................................................204
Figure 13.36: Australia Neurodegenerative Disorder Therapeutics Market, 2019-2030.................205
Figure 13.37: Australia Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030
.......................................................................................................................................................206
Figure 13.38: RoAPAC Neurodegenerative Disorder Therapeutics Market, 2019-2030................207
Figure 13.39: RoAPAC Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030
.......................................................................................................................................................208
Figure 13.40: Latin America Neurodegenerative Disorder Therapeutics Market, 2019-2030.........210
Figure 13.41: Latin America Neurodegenerative Disorder Therapeutics Market (by Country), 2019-
2030...............................................................................................................................................210
Figure 13.42: Revenue Contributions Different Countries in Latin America, 2019 and 2030..........211
Figure 13.43: Brazil Neurodegenerative Disorder Therapeutics Market, 2019-2030......................212
Figure 13.44: Brazil Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030
.......................................................................................................................................................213
Figure 13.45: Mexico Neurodegenerative Disorder Therapeutics Market, 2019-2030...................214
Figure 13.46: Mexico Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030
.......................................................................................................................................................215
Figure 13.47: Rest-of-Latin America Neurodegenerative Disorder Therapeutics Market, 2019-2030
.......................................................................................................................................................216
Figure 13.48: RoLATAM Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-
2030...............................................................................................................................................217
Figure 13.49: RoW Neurodegenerative disorder therapeutics market, 2019-2030 ........................218
Global Neurodegenerative Disorder Therapeutics Market
All rights reserved at BIS Research 24
Figure 14.1: Share of Key Developments and Strategies, July 2015 - July 2020..........................220
Figure 14.2: Regulatory and Legal Developments Share (by Company), July 2015 - July 2020...221
Figure 14.3: Partnerships, Alliances, and Business Expansions (by Company), July 2015 - July 2020
.......................................................................................................................................................222
Figure 14.4: M&A Activities Share (by Company), July 2015 - July 2020 ......................................223
Figure 14.5: Market Share Analysis (by Companies), 2018 and 2019...........................................224
Figure 15.1: Total Number of Companies Profiled.........................................................................226
Figure 15.2: AbbVie Inc.: Overall Product Portfolio........................................................................228
Figure 15.3: AbbVie Inc.Overall Financials, 2017-2019.................................................................230
Figure 15.4: AbbVie Inc.: Revenue (by Region), 2017-2019..........................................................231
Figure 15.5: AbbVie Inc.: R&D Expenditure, 2017-2019................................................................232
Figure 15.6: AbbVie Inc.: SWOT Analysis .....................................................................................233
Figure 15.7: Bayer AG: Overall Product Portfolio...........................................................................235
Figure 15.8: Bayer AG: Overall Financials, 2017-2019..................................................................235
Figure 15.9: Bayer AG: Revenue (by Segment), 2018-2019 .........................................................236
Figure 15.10: Bayer AG: Revenue (by Region), 2017-2019 ..........................................................237
Figure 15.11: Bayer AG: R&D Expenditure, 2017-2019.................................................................237
Figure 15.12: Bayer AG: SWOT Analysis......................................................................................238
Figure 15.13: Biogen Inc.: Overall Service Portfolio.......................................................................240
Figure 15.14: Biogen Inc.: Overall Financials, 2017-2019..............................................................243
Figure 15.15: Biogen Inc.: Sales (by Product), 2017-2019.............................................................244
Figure 15.16: Biogen Inc.: Sales (by Region), 2017-2019..............................................................244
Figure 15.17: Biogen Inc.: R&D Expenditure, 2017-2019 ..............................................................245
Figure 15.18: Biogen Inc.: SWOT Analysis....................................................................................246
Figure 15.19: Bristol Myers Squibb Company: Overall Product Portfolio .......................................248
Figure 15.20: Bristol Myers Squibb Company: Overall Financials, 2017-2019 ..............................249
Figure 15.21: Bristol Myers Squibb Company: Revenue (by Region), 2017-2019.........................250
Figure 15.22: Bristol Myers Squibb Company: R&D Expenditure, 2017-2019...............................250
Figure 15.23: Bristol Myers Squibb Company: SWOT Analysis.....................................................251
Figure 15.24: C. H. Boehringer Sohn AG & Co. KG: Overall Product Portfolio..............................253
Figure 15.25: C. H. Boehringer Sohn AG & Co. KG: Overall Financials, 2017-2019 .....................254
Global Neurodegenerative Disorder Therapeutics Market
All rights reserved at BIS Research 25
Figure 15.26: C. H. Boehringer Sohn AG & Co. KG: Revenue (by Segment), 2017-2019.............255
Figure 15.27: C. H. Boehringer Sohn AG & Co. KG: Revenue (by Region), 2017-2019................255
Figure 15.28: C. H. Boehringer Sohn AG & Co. KG: R&D Expenditure, 2017-2019......................256
Figure 15.29: C. H. Boehringer Sohn AG & Co. KG: SWOT Analysis............................................257
Figure 15.30: Eisai Inc.: Overall Product Portfolio..........................................................................259
Figure 15.31: Eisai Inc.: Overall Financials, 2017-2019.................................................................261
Figure 15.32: Eisai Inc.: Revenue (by Segment), 2017-2019.........................................................262
Figure 15.33: Eisai Inc.: Revenue (by Region), 2017-2019............................................................263
Figure 15.34: Eisai Inc.: R&D Expenditure, 2017-2019..................................................................264
Figure 15.35: Eisai Inc.: SWOT Analysis .......................................................................................265
Figure 15.36: F. Hoffmann-La Roche Ltd: Product Portfolio ..........................................................267
Figure 15.37: F. Hoffmann-La Roche Ltd: Overall Financials, 2017-2019 .....................................269
Figure 15.38: F. Hoffmann-La Roche Ltd: Revenue (by Segment), 2017-2019.............................270
Figure 15.39: F. Hoffmann-La Roche Ltd: Revenue (by Region), 2017-2019................................271
Figure 15.40: F. Hoffmann-La Roche Ltd: R&D Expenditure, 2017-2019......................................271
Figure 15.41: F. Hoffmann-La Roche Ltd: SWOT Analysis............................................................272
Figure 15.42: GlaxoSmithKline plc: Overall Product Portfolio ........................................................274
Figure 15.43: GlaxoSmithKline plc: Overall Financials, 2017-2019................................................275
Figure 15.44: GlaxoSmithKline plc: Revenue (by Segment), 2017-2019.......................................276
Figure 15.45: GlaxoSmithKline plc: Revenue (by Region), 2017-2019..........................................277
Figure 15.46: GlaxoSmithKline plc: R&D Expenditure, 2017-2019 ................................................278
Figure 15.47: GlaxoSmithKline plc: SWOT Analysis......................................................................279
Figure 15.48: H. Lundbeck A/S: Overall Product Portfolio .............................................................281
Figure 15.49: H. Lundbeck A/S: Overall Financials, 2017-2019.....................................................282
Figure 15.50: H. Lundbeck A/S: Revenue (by Segment), 2017-2019............................................283
Figure 15.51: H. Lundbeck A/S: Revenue (by Region), 2017-2019 ...............................................284
Figure 15.52: H. Lundbeck A/S: R&D Expenditure, 2017-2019 .....................................................284
Figure 15.53: H. Lundbeck A/S: SWOT Analysis...........................................................................285
Figure 15.54: Merck KGaA: Product Portfolio................................................................................287
Figure 15.55: Merck KGaA: Overall Financials, 2017-2019...........................................................288
Figure 15.56: Merck KGaA: Revenue (by Segment), 2017-2019...................................................289
Global Neurodegenerative Disorder Therapeutics Market
All rights reserved at BIS Research 26
Figure 15.57: Merck KGaA: Revenue (by Region), 2017-2019......................................................290
Figure 15.58: Merck KGaA: R&D Expenditure, 2017-2019............................................................290
Figure 15.59: Merck KGaA: SWOT Analysis .................................................................................291
Figure 15.60: Novartis AG: Overall Financials, 2017-2019 ............................................................294
Figure 15.61: Novartis AG Net Revenue (by Business Segment), 2017-2019...............................295
Figure 15.62: Novartis AG: Net Revenue (by Region), 2017-2019 ................................................296
Figure 15.63: Novartis AG: R& D Expense, 2017-2019.................................................................296
Figure 15.64: Novartis AG: SWOT Analysis ..................................................................................297
Figure 15.65: Pfizer Inc.: Overall Product Portfolio ........................................................................299
Figure 15.66: Pfizer Inc.: Overall Financials, 2017-2019................................................................300
Figure 15.67: Pfizer Inc.: Revenue (by Segment), 2017-2019 .......................................................301
Figure 15.68: Pfizer Inc.: Revenue Split (by Biopharma Segment), 2017-2019.............................301
Figure 15.69: Pfizer Inc.: Revenue (by Region), 2017-2019 ..........................................................302
Figure 15.70: Pfizer Inc: R&D Expenditure, 2017-2019 .................................................................303
Figure 15.71: Pfizer Inc.: SWOT Analysis......................................................................................304
Figure 15.72: Sanofi SA: Overall Product Portfolio ........................................................................306
.......................................................................................................................................................306
Figure 15.73: Sanofi SA: Overall Financials, 2017-2019................................................................308
Figure 15.74: Sanofi SA: Revenue (by Segment), 2017-2019.......................................................309
Figure 15.75: Sanofi SA: Revenue (by Region), 2017-2019..........................................................309
Figure 15.76: Sanofi SA: R&D Expenditure, 2017-2019 ................................................................310
Figure 15.77: Sanofi SA: SWOT Analysis......................................................................................311
Figure 15.78: Teva Pharmaceutical Industries Ltd.: Overall Product Offerings for Global
Neurodegenerative Disorder Therapeutics Market ........................................................................313
Figure 15.79: Teva Pharmaceutical Industries Ltd.: Overall Financials, 2017-2019.......................314
Figure 15.80: Teva Pharmaceutical Industries Ltd.: Net Revenue (by Business Segment), 2017-2019
.......................................................................................................................................................315
Figure 15.81: Teva Pharmaceutical Industries Ltd.: Research and Development Expense, 2017-2019
.......................................................................................................................................................316
Figure 15.82: Teva Pharmaceutical Industries Ltd.: SWOT Analysis.............................................317
Figure 15.83: UCB Pharma SA: Overall Product Portfolio .............................................................319
Global Neurodegenerative Disorder Therapeutics Market
All rights reserved at BIS Research 27
Figure 15.84: UCB Pharma SA: Overall Financials, 2017-2019.....................................................320
Figure 15.85: UCB Pharma SA: Revenue (by Product), 2017-2019..............................................321
Figure 15.86: UCB Pharma SA: Revenue (by Region), 2017-2019...............................................322
Figure 15.87: UCB Pharma SA: R&D Expenditure, 2017-2019 .....................................................322
Figure 15.88: UCB Pharma SA: SWOT Analysis...........................................................................323
Global Neurodegenerative Disorder Therapeutics Market
All rights reserved at BIS Research 28
List of Tables
Table 1: Leading Players in Global Neurodegenerative Disorder Therapeutics Market...................35
Table 4.1: Comparison of Drug Development Within and Outside the Central Nervous System .....54
Table 4.2: Commercialized Neurodegenerative Disorders Therapeutic Products............................55
Table 8.1: Regulatory Scenario Across the World ...........................................................................85
Table 8.2: Expedited Regulatory Designations Around the World ...................................................98
Table 8.3: Current Regulatory Development Guidelines for Neurodegenerative Disorders ...........101
Table 15.1: AbbVie Inc.: Pipeline Product Portfolio........................................................................230
Table 15.2: Biogen Inc.: Pipeline Product Portfolio ........................................................................242
Table 15.3: Bristol Myers Squibb Company: Pipeline Product Portfolio.........................................249
Table 15.4: C. H. Boehringer Sohn AG & Co. KG Company: Pipeline Product Portfolio................254
Table 15.5: C. H. Boehringer Sohn AG & Co. KG Company: Pipeline Product Portfolio................261
Table 15.6: F. Hoffmann-La Roche Ltd.: Pipeline Product Portfolio...............................................268
Table 15.7: H. Lundbeck A/S Company: Pipeline Product Portfolio...............................................283
Table 15.8: Merck KGaA: Pipeline Product Portfolio......................................................................288
Table 15.9: Novartis AG: Pipeline Product Portfolio.......................................................................294
Table 15.10: Pfizer Plc: Pipeline Product Portfolio.........................................................................300
Table 15.11: Sanofi SA: Pipeline Product Portfolio........................................................................307
Table 15.12: Teva Pharmaceutical Industries Ltd Company: Pipeline Product Portfolio................315
Table 15.13: UCB Pharma SA Company: Pipeline Product Portfolio.............................................321
Global Neurodegenerative Disorder Therapeutics Market
All rights reserved at BIS Research 29
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Global Neurodegenerative Disorder Therapeutics Market

  • 1. All rights reserved at BIS Research 1 Global Neurodegenerative Disorder Therapeutics Market Focus on Product, Mechanism, Route of Administration, Indication, Country Data (14 Countries), and Competitive Landscape: Analysis and Forecast: 2019-2030 October 2020 TOC
  • 2. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 2 BIS Research is a leading market intelligence and technology research company. BIS Research publishes in-depth market intelligence reports focusing on the market estimations, technology analysis, emerging high-growth applications, deeply segmented granular country-level market data and other important market parameters useful in the strategic decision making for senior management. BIS Research provides multi-client reports, company profiles, databases, and custom research services. Copyright © 2020 BIS Research Inc. All Rights Reserved. This document contains highly confidential information and is the sole property of BIS Research. Disclosing, copying, circulating, quoting, or otherwise reproducing any or all contents of this document is strictly prohibited. Access to this information is provided exclusively for the benefit of the people or organization concerned. It may not be accessed by or offered whether for sale or otherwise to any third party.
  • 3. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 3 Table of Contents Executive Summary…………………………………………………………….20 1. Technology Definition.......................................................................................... 41 1.1 Inclusion and Exclusion Criteria................................................................ 41 1.1.1 Inclusions...................................................................................... 41 1.1.2 Exclusions .................................................................................... 42 2. Research Scope.................................................................................................... 43 2.1 Key Questions Answered in the Report.................................................... 45 3. Research Methodology ........................................................................................ 47 3.1 Neurodegenerative Disorder Therapeutics: Research Methodology ..... 47 3.2 Primary Data Sources................................................................................. 48 3.3 Secondary Data Sources............................................................................ 49 3.4 Market Estimation Model............................................................................ 49 3.5 Criteria for Company Profiling................................................................... 52 4. Market Overview................................................................................................... 53 4.1 Neurodegenerative Disorder Therapeutics and Its Clinical Importance 53 4.2 Neurodegenerative Disorder Therapeutics Development and Commercialization Landscape................................................................... 55 4.3 Global Neurodegenerative Disorder Therapeutics Market and Growth Potential, 2019-2030.................................................................................... 57 4.4 Pricing and Reimbursement Scenario....................................................... 58 4.5 Impact of Patent Expiry and Entry of Biosimilars on Market .................. 59 4.6 Impact of COVID-19 on Neurodegenerative Disorder Therapeutics Market........................................................................................................... 61 5. Epidemiology of Neurodegenerative Disorder Therapeutics ........................... 64 6. Patent Landscape................................................................................................. 73
  • 4. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 4 7. Market Dynamics.................................................................................................. 77 7.1 Overview ...................................................................................................... 77 7.2 Impact Analysis........................................................................................... 77 7.3 Drivers.......................................................................................................... 78 7.3.1 Rising Global Prevalence of Neurodegenerative Disorders..... 78 7.3.2 The Increase in Number of Geriatric Populations ..................... 80 7.3.3 Increasing Research Funding in Neurodegenerative Disorders ....................................................................................................... 81 7.3.4 Rising Awareness about Neurodegenerative Disorders........... 82 7.4 Restraints..................................................................................................... 82 7.4.1 High Failure Rate of Neurodegenerative Drugs in Clinical Trials ....................................................................................................... 82 7.4.2 Lack of Effective Drugs and Therapies ...................................... 83 7.5 Opportunities............................................................................................... 84 8. Industry Insights................................................................................................... 85 8.1 Overview ...................................................................................................... 85 8.2 Regulatory Scenario ................................................................................... 85 8.3 Legal Requirements and Frameworks in the U.S..................................... 87 8.3.1 Clinical Trial Authorization.......................................................... 87 8.3.2 Marketing Authorization .............................................................. 88 8.3.3 USFDA Guidelines for BLA Submission .................................... 90 8.3.4 Post-Authorization Regulations.................................................. 91 8.4 Legal Requirements and Frameworks in Europe ..................................... 91 8.4.1 EMA Biologics License Application Process............................. 93 8.4.2 Centralized Procedure ................................................................. 94 8.4.3 Decentralized Procedure ............................................................. 94 8.4.4 Mutual-Recognition Procedure ................................................... 94 8.4.5 National Procedure....................................................................... 95 8.5 Legal Requirements and Frameworks in Asia-Pacific ............................. 95 8.5.1 China ............................................................................................. 95 8.5.2 Japan............................................................................................. 96
  • 5. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 5 8.6 Expedited Regulatory Designations Around the World........................... 97 8.7 Role of Regulatory Bodies and Consortium in Neurodegenerative Disorder Therapeutics .............................................................................. 100 8.8 Regulatory Guidelines .............................................................................. 100 8.8.1 Terminology Applied in Current Regulatory Guidelines for Development of Drugs to Treat Neurodegenerative Disorders ..................................................................................................... 100 8.8.2 Actionable Recommendations .................................................. 102 8.8.2.1 EU:.......................................................................................... 102 8.8.2.2 EU:.......................................................................................... 102 8.8.2.3 Both Regions: ......................................................................... 103 8.9 Regulatory Challenges ............................................................................. 103 8.10 Reimbursement and Market Access........................................................ 104 9. Global Neurodegenerative Disorder Therapeutics Market, by Product Type ($Million), 2019-2030........................................................................................... 106 9.1 Commercialized Therapeutics ................................................................. 106 9.1.1 Multiple Sclerosis....................................................................... 106 9.1.1.1 Tecfidera................................................................................. 106 9.1.1.2 Ocrevus................................................................................... 107 9.1.1.3 Gilenya.................................................................................... 107 9.1.1.4 Aubagio................................................................................... 108 9.1.1.5 Interferon (Avonex and Plegridy)............................................. 108 9.1.1.6 Tysabri .................................................................................... 109 9.1.1.7 Rebif........................................................................................ 109 9.1.1.8 Copaxone................................................................................ 110 9.1.1.9 Betaseron................................................................................ 110 9.1.1.10 Lemtrada................................................................................. 111 9.1.1.11 Mavenclad............................................................................... 111 9.1.1.12 Fampyra.................................................................................. 112 9.1.1.13 Ampyra.................................................................................... 112 9.1.1.14 Mayzent .................................................................................. 113 9.1.1.15 Vumerity.................................................................................. 113
  • 6. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 6 9.1.1.16 Others ..................................................................................... 114 9.1.2 Epilepsy....................................................................................... 114 9.1.2.1 Lyrica ...................................................................................... 115 9.1.2.2 Vimpat..................................................................................... 115 9.1.2.3 Onfi ......................................................................................... 116 9.1.2.4 Keppra .................................................................................... 116 9.1.2.5 Sabril....................................................................................... 117 9.1.2.6 Briviact .................................................................................... 117 9.1.2.7 Fycompa ................................................................................. 118 9.1.2.8 Banzel..................................................................................... 118 9.1.2.9 Others ..................................................................................... 119 9.1.3 Alzheimer’s Market..................................................................... 119 9.1.3.1 Ebixa....................................................................................... 120 9.1.3.2 Namenda XR .......................................................................... 120 9.1.3.3 Namzaric................................................................................. 121 9.1.3.4 Galantamine............................................................................ 121 9.1.3.5 Others ..................................................................................... 122 9.1.4 Parkinson’s Disease................................................................... 122 9.1.4.1 Azilect ..................................................................................... 123 9.1.4.2 Neupro .................................................................................... 123 9.1.4.3 Madopar.................................................................................. 124 9.1.4.4 Duopa ..................................................................................... 124 9.1.4.5 Inbrija ...................................................................................... 125 9.1.4.6 Others ..................................................................................... 125 9.1.5 Spinal Muscular Atrophy (SMA)................................................ 126 9.1.5.1 Spinraza.................................................................................. 126 9.1.5.2 Zolgensma .............................................................................. 127 9.1.5.3 Others ..................................................................................... 127 9.1.6 Huntington’s Disease................................................................. 128 9.1.6.1 Austedo................................................................................... 128 9.1.6.2 Xenazine................................................................................. 129
  • 7. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 7 9.1.6.3 Others ..................................................................................... 129 9.2 Pipeline Therapeutics ............................................................................... 130 9.2.1 Multiple Sclerosis....................................................................... 130 9.2.1.1 Zeposia ................................................................................... 130 9.2.1.2 Ponesimod .............................................................................. 130 9.2.1.3 Ofatumumab ........................................................................... 131 9.2.1.4 Ublituximab ............................................................................. 131 9.2.1.5 Ibudilast................................................................................... 132 9.2.1.6 SAR442168............................................................................. 132 9.2.2 Alzheimer’s Disease................................................................... 133 9.2.2.1 Tricaprilin ................................................................................ 133 9.2.2.2 Bryostatin-1............................................................................. 133 9.2.2.3 AGB101 .................................................................................. 134 9.2.2.4 COR388.................................................................................. 134 9.2.2.5 TRx0237 ................................................................................. 135 9.2.2.6 Brexpiprazole .......................................................................... 135 9.2.2.7 Semorinemab.......................................................................... 136 9.2.2.8 Aducanumab........................................................................... 136 9.2.3 Parkinson’s Disease................................................................... 137 9.2.3.1 Eltoprazine.............................................................................. 137 9.2.3.2 Ongentys................................................................................. 137 9.2.3.3 IPX-066................................................................................... 138 9.2.3.4 Xadago.................................................................................... 138 9.2.3.5 Nourianz.................................................................................. 139 9.2.3.6 Opicapone............................................................................... 139 9.2.4 Huntington’s Disease................................................................. 140 9.2.4.1 RG6042/IONIS -HTTrx............................................................ 140 9.2.4.2 WVE-120101........................................................................... 140 9.2.4.3 WVE-120102........................................................................... 141 10. Global Neurodegenerative Disorder Therapeutics Market, by Drug Class ($Million), 2019-2030........................................................................................... 142
  • 8. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 8 10.1 Introduction ............................................................................................... 142 10.2 Immunomodulators................................................................................... 143 10.3 Interferons ................................................................................................. 145 10.4 Dopamine Agonists .................................................................................. 146 10.5 Decarboxylase Inhibitors.......................................................................... 148 10.6 Others......................................................................................................... 149 11. Global Neurodegenerative Disorder Therapeutics Market, by Indication ($Million), 2019-2030........................................................................................... 151 11.1 Overview .................................................................................................... 151 11.2 Multiple Sclerosis...................................................................................... 153 11.3 Epilepsy ..................................................................................................... 154 11.4 Spinal Muscular Atrophy (SMA)............................................................... 155 11.5 Alzheimer’s Disease ................................................................................. 157 11.6 Parkinson’s Disease ................................................................................. 158 11.7 Huntington’s Disease................................................................................ 159 11.8 Other Neurological Disorders .................................................................. 161 12. Global Neurodegenerative Disorder Therapeutics Market, by Route of Drug Administration ($Million), 2019-2030 ................................................................ 162 12.1 Introduction ............................................................................................... 162 12.2 Oral............................................................................................................. 163 12.3 Injectable.................................................................................................... 164 12.4 Enteral........................................................................................................ 165 12.5 Transdermal............................................................................................... 166 12.6 Others......................................................................................................... 166 13. Global Neurodegenerative Disorder Therapeutics Market, by Region ($Million), 2019-2030........................................................................................... 168 13.1 Overview .................................................................................................... 168 13.2 North America ........................................................................................... 170 13.2.1 U.S. .............................................................................................. 173
  • 9. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 9 13.2.1.1 U.S. Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 175 13.2.2 Canada ........................................................................................ 176 13.2.2.1 Canada Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 177 13.3 Europe........................................................................................................ 178 13.3.1 Germany...................................................................................... 181 13.3.1.1 Germany Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 182 13.3.2 U.K. .............................................................................................. 183 13.3.2.1 U.K. Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 184 13.3.3 France.......................................................................................... 185 13.3.3.1 France Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 186 13.3.4 Italy .............................................................................................. 187 13.3.4.1 Italy Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 188 13.3.5 Spain............................................................................................ 189 13.3.5.1 Spain Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 190 13.3.6 Rest-of-Europe ........................................................................... 191 13.3.6.1 RoE Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 192 13.4 Asia-Pacific................................................................................................ 193 13.4.1 China ........................................................................................... 196 13.4.1.1 China Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 198 13.4.2 Japan........................................................................................... 199 13.4.2.1 Japan Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 201 13.4.3 India............................................................................................. 201 13.4.3.1 India Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 203
  • 10. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 10 13.4.4 South Korea................................................................................ 204 13.4.4.1 South Korea Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ...................................................... 205 13.4.5 Australia...................................................................................... 206 13.4.5.1 Australia Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 207 13.4.6 Rest-of-APAC.............................................................................. 208 13.4.6.1 RoAPAC Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 209 13.5 Latin America ............................................................................................ 210 13.5.1 Brazil............................................................................................ 213 13.5.1.1 Brazil Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 214 13.5.2 Mexico ......................................................................................... 215 13.5.2.1 Mexico Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 216 13.5.3 Rest-of-Latin America ................................................................ 217 13.5.3.1 RoLATAM Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ............................................................ 218 13.6 Rest-of-the-World...................................................................................... 219 14. Competitive Landscape ..................................................................................... 220 14.1 Key Developments and Strategies .......................................................... 220 14.1.1 Regulatory and Legal Developments........................................ 222 14.1.2 Partnerships, Alliances, and Business Expansions................ 222 14.1.3 M&A Activities ............................................................................ 223 14.1.4 Funding Activities ...................................................................... 224 14.2 Market Share Analysis.............................................................................. 225 15. Company Profiles............................................................................................... 227 15.1 Overview .................................................................................................... 227 15.2 AbbVie Inc.................................................................................................. 228 15.2.1 Company Overview .................................................................... 228
  • 11. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 11 15.2.2 Role of AbbVie Inc. in Global Neurodegenerative Disorder Therapeutics Market .................................................................. 228 15.2.3 Financials.................................................................................... 231 15.2.4 Key Insights about Financial Health of the Company............. 233 15.2.5 SWOT Analysis........................................................................... 234 15.3 Bayer AG.................................................................................................... 235 15.3.1 Company Overview .................................................................... 235 15.3.2 Role of Bayer AG in Global Neurodegenerative Disorder Therapeutics Market .................................................................. 235 15.3.3 Financials.................................................................................... 236 15.3.4 Key Insight about Financial Health of the Company............... 238 15.3.5 SWOT Analysis........................................................................... 239 15.4 Biogen Inc.................................................................................................. 240 15.4.1 Company Overview .................................................................... 240 15.4.2 Role of Biogen Inc. in Global Neurodegenerative Disorder Therapeutics Market .................................................................. 240 15.4.3 Financials.................................................................................... 244 15.4.4 Key Insights about Financial Health of the Company............. 246 15.4.5 SWOT Analysis........................................................................... 247 15.5 Bristol-Myers Squibb Company............................................................... 248 15.5.1 Company Overview .................................................................... 248 15.5.2 Role of Bristol Myers Squibb Company in Global Neurodegenerative Disorder Therapeutics Market ................. 248 15.5.3 Financials.................................................................................... 250 15.5.4 Key Insights About Financial Health of the Company ............ 251 15.5.5 SWOT Analysis........................................................................... 252 15.6 C. H. Boehringer Sohn AG & Co. KG....................................................... 253 15.6.1 Company Overview .................................................................... 253 15.6.2 Role of C. H. Boehringer Sohn AG & Co. KG in Global Neurodegenerative Disorder Therapeutics Market ................. 253 15.6.3 Financials.................................................................................... 255 15.6.4 Key Insight about Financial Health of the Company............... 257 15.6.5 SWOT Analysis........................................................................... 258
  • 12. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 12 15.7 Eisai Inc...................................................................................................... 259 15.7.1 Company Overview .................................................................... 259 15.7.2 Role of Eisai Inc. in Global Neurodegenerative Disorder Therapeutics Market .................................................................. 259 15.7.3 Financials.................................................................................... 262 15.7.4 Key Insight about Financial Health of the Company............... 265 15.7.5 SWOT Analysis........................................................................... 266 15.8 F. Hoffmann-La Roche Ltd. ...................................................................... 267 15.8.1 Company Overview .................................................................... 267 15.8.2 Role of F. Hoffmann-La Roche Ltd. in Global Neurodegenerative Disorder Therapeutics Market................................................... 267 15.8.3 Financials.................................................................................... 270 15.8.4 Key Insights About Financial Health of the Company ............ 272 15.8.5 SWOT Analysis........................................................................... 273 15.9 GlaxoSmithKline plc ................................................................................. 274 15.9.1 Company Overview .................................................................... 274 15.9.2 Role of GlaxoSmithKline plc in Global Neurodegenerative Disorder Therapeutics Market................................................... 274 15.9.3 Financials.................................................................................... 276 15.9.4 Key Insights about Financial Health of the Company............. 279 15.9.5 SWOT Analysis........................................................................... 280 15.10H. Lundbeck A/S........................................................................................ 281 15.10.1 Company Overview .................................................................... 281 15.10.2 Role of H. Lundbeck A/S in Global Neurodegenerative Disorder Therapeutics Market .................................................................. 281 15.10.3 Financials.................................................................................... 283 15.10.4 Key Insight about Financial Health of the Company............... 285 15.10.5 SWOT Analysis........................................................................... 286 15.11Merck KGaA............................................................................................... 287 15.11.1 Company Overview .................................................................... 287 15.11.2 Role of Merck KGaA in Global Neurodegenerative Disorder Therapeutics Market .................................................................. 287 15.11.3 Financials.................................................................................... 289
  • 13. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 13 15.11.4 Key Insights About Financial Health of the Company ............ 291 15.11.5 SWOT Analysis........................................................................... 292 15.12Novartis AG ............................................................................................... 293 15.12.1 Company Overview .................................................................... 293 15.12.2 Role of Novartis AG in Global Neurodegenerative Disorder Therapeutics Market .................................................................. 293 15.12.3 Financials.................................................................................... 295 15.12.4 Key Insights About Financial Health of the Company ............ 297 15.12.5 SWOT Analysis........................................................................... 298 15.13Pfizer Inc. ................................................................................................... 299 15.13.1 Company Overview .................................................................... 299 15.13.2 Role of Pfizer Inc. in Global Neurodegenerative Disorder Therapeutics Market .................................................................. 299 15.13.3 Financials.................................................................................... 301 15.13.4 Key Insights About Financial Health of the Company ............ 304 15.13.5 SWOT Analysis........................................................................... 305 15.14Sanofi S.A. ................................................................................................. 306 15.14.1 Company Overview .................................................................... 306 15.14.2 Role of Sanofi SA in Global Neurodegenerative Disorder Therapeutics Market .................................................................. 306 15.14.3 Financials.................................................................................... 309 15.14.4 Key Insights About Financial Health of the Company ............ 311 15.14.5 SWOT Analysis........................................................................... 312 15.15Teva Pharmaceutical Industries Ltd........................................................ 313 15.15.1 Company Overview .................................................................... 313 15.15.2 Role of Teva Pharmaceutical Industries Ltd. in Global Neurodegenerative Disorder Therapeutics Market ................. 313 15.15.3 Financials.................................................................................... 315 15.15.4 Key Insight about Financial Health of the Company............... 317 15.15.5 SWOT Analysis........................................................................... 318 15.16UCB Pharma SA. ....................................................................................... 319 15.16.1 Company Overview .................................................................... 319
  • 14. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 14 15.16.2 Role of UCB Pharma SA in Global Neurodegenerative Disorder Therapeutics Market .................................................................. 319 15.16.3 Financials.................................................................................... 321 15.16.4 Key Insight about Financial Health of the Company............... 323 15.16.5 SWOT Analysis........................................................................... 324
  • 15. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 15 List of Figures Figure 1: Global Total Burden of Diseases by Cause ......................................................................30 Figure 2: Global Geriatric Population by Age...................................................................................31 Figure 3: Global Neurodegenerative Disorder Therapeutics Market................................................32 Figure 4: Impact Analysis.................................................................................................................33 Figure 5: Share of Key Developments and Strategies, June 2015-June 2020.................................35 Figure 6: Global Neurodegenerative Disorder Therapeutics Market (by Drug Class), 2019 and 2030 .........................................................................................................................................................36 Figure 7: Global Neurodegenerative Disorder Therapeutics Market (by Indication), 2019 and 2030 .........................................................................................................................................................37 Figure 8: Global Neurodegenerative Disorder Therapeutics Market (by Route of Administraton), 2019 and 2030..........................................................................................................................................38 Figure 9: Global Neurodegenerative Disorder Therapeutics Market (by Region), 2019-2030..........39 Figure 2.1: Global Neurodegenerative Disorder Therapeutics Market Segmentation......................43 Figure 3.1: Global Neurodegenerative Disorder Therapeutic Market Methodology .........................46 Figure 3.2: Primary Research Methodology.....................................................................................47 Figure 3.3: Bottom-Up Approach (Segment-Wise Analysis) ............................................................49 Figure 3.4: Top-Down Approach (Segment-Wise Analysis).............................................................49 Figure 4.1: Neurodegenerative Disorder Therapeutics Clinical Trial Landscape..............................53 Figure 4.2: Global Neurodegenerative Disorder Market 2019-2030.................................................57 Figure 4.3: Patent Expiry of Neurodegenerative Disorder Therapies...............................................59 Figure 4.4: Most Impacted Practices in the Treatment of Neurodegenerative Disorders .................61 Figure 5.1: Prevalence of Neurodegenerative Disorders in the U.S. (Total Population)...................64 Figure 5.2: Prevalence of Alzheimer’s Disease in the U.S. (Total Population).................................65 Figure 5.3: Prevalence of Epilepsy in the U.S. (Total Population)....................................................65 Figure 5.4: Prevalence of Parkinson’s Disease in the U.S. (Total Population).................................66 Figure 5.5: Prevalence of Multiple Sclerosis in the U.S. (Total Population)......................................66 Figure 5.6: Prevalence of Spinal Muscular Atrophy (SMA) in the U.S. (Total Population)................67 Figure 5.7: Prevalence of Huntington's Disease in the U.S. (Total Population)................................67 Figure 5.8: Target Population of Epilepsy in the U.S........................................................................69
  • 16. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 16 Figure 5.9: Target Population of Alzheimer’s Disease in the U.S.....................................................69 Figure 5.10: Target Population of Multiple Sclerosis in the U.S. ......................................................70 Figure 5.11: Target Population of Parkinson’s Disease in the U.S...................................................70 Figure 5.12: Target Population of Huntington's Disease in the U.S..................................................71 Figure 6.1: Number of Patents Filed, Neurodegenerative Disorder Therapeutics/Drugs, January 2015- December 2019...............................................................................................................................72 Figure 6.2: Number of Patents Filed, Multiple Sclerosis Therapeutics/Drugs, January 2015-December 2019.................................................................................................................................................73 Figure 6.3: Number of Patents Filed, Alzheimer’s Disease Therapeutics/Drugs, January 2015- December 2019...............................................................................................................................74 Figure 6.4: Percentage of Patents Filed, By Patent Office, January 2015-December 2019.............75 Figure 7.1: Impact Analysis..............................................................................................................77 Figure 7.2: Global Total Burden of Diseases by Cause ...................................................................78 Figure 7.3: Global Geriatric Population by Age................................................................................80 Figure 8.1: Steps for Obtaining Marketing Authorization..................................................................88 Figure 8.2: USFDA Review Timeline ...............................................................................................89 Figure 8.3: EMA Review Timeline....................................................................................................92 Figure 9.1: Global Neurodegenerative Disorder Therapeutics Market (Tecfidera - Product Revenue), 2019-2030 .....................................................................................................................................105 Figure 9.2: Global Neurodegenerative Disorder Therapeutics Market (Ocrevus – Product Revenue), 2019-2030 .....................................................................................................................................106 Figure 9.3: Global Neurodegenerative Disorder Therapeutics Market (Gilenya – Product Revenue), 2019-2030 .....................................................................................................................................106 Figure 9.4: Global Neurodegenerative Disorder Therapeutics Market (Aubagio – Product Revenue), 2019-2030 .....................................................................................................................................107 Figure 9.5: Global Neurodegenerative Disorder Therapeutics Market (Interferon (Avonex and Plegridy) – Product Revenue), 2019-2030.....................................................................................107 Figure 9.6: Global Neurodegenerative Disorder Therapeutics Market (Tysabri – Product Revenue), 2019-2030 .....................................................................................................................................108 Figure 9.7: Global Neurodegenerative Disorder Therapeutics Market (Rebif – Product Revenue), 2019-2030 .....................................................................................................................................108
  • 17. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 17 Figure 9.8: Global Neurodegenerative Disorder Therapeutics Market (Copaxone – Product Revenue), 2019-2030 .....................................................................................................................................109 Figure 9.9: Global Neurodegenerative Disorder Therapeutics Market (Betaseron – Product Revenue), 2019-2030 .....................................................................................................................................109 Figure 9.10: Global Neurodegenerative Disorder Therapeutics Market (Lemtrada – Product Revenue), 2019-2030....................................................................................................................110 Figure 9.11: Global Neurodegenerative Disorder Therapeutics Market (Mavenclad – Product Revenue), 2019-2030....................................................................................................................110 Figure 9.12: Global Neurodegenerative Disorder Therapeutics Market (Fampyra – Product Revenue), 2019-2030 .....................................................................................................................................111 Figure 9.13: Global Neurodegenerative Disorder Therapeutics Market (Ampyra – Product Revenue), 2019-2030 .....................................................................................................................................111 Figure 9.14: Global Neurodegenerative Disorder Therapeutics Market (Mayzent – Product Revenue), 2019-2030 .....................................................................................................................................112 Figure 9.15: Global Neurodegenerative Disorder Therapeutics Market (Vumerity – Product Revenue), 2019-2030 .....................................................................................................................................112 Figure 9.16: Global Neurodegenerative Disorder Therapeutics Market (Others – Product Revenue), 2019-2030 .....................................................................................................................................113 Figure 9.17: Global Neurodegenerative Disorder Therapeutics Market (Lyrica – Product Revenue), 2019-2030 .....................................................................................................................................114 Figure 9.18: Global Neurodegenerative Disorder Therapeutics Market (Vimpat – Product Revenue), 2019-2030 .....................................................................................................................................114 Figure 9.19: Global Neurodegenerative Disorder Therapeutics Market (Onfi – Product Revenue), 2019-2030 .....................................................................................................................................115 Figure 9.20: Global Neurodegenerative Disorder Therapeutics Market (Keppra – Product Revenue), 2019-2030 .....................................................................................................................................115 Figure 9.21: Global Neurodegenerative Disorder Therapeutics Market (Sabril – Product Revenue), 2019-2030 .....................................................................................................................................116 Figure 9.22: Global Neurodegenerative Disorder Therapeutics Market (Briviact – Product Revenue), 2019-2030 .....................................................................................................................................116
  • 18. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 18 Figure 9.23: Global Neurodegenerative Disorder Therapeutics Market (Fycompa – Product Revenue), 2019-2030....................................................................................................................117 Figure 9.24: Global Neurodegenerative Disorder Therapeutics Market (Banzel – Product Revenue), 2019-2030 .....................................................................................................................................117 Figure 9.25: Global Neurodegenerative Disorder Therapeutics Market (Others – Product Revenue), 2019-2030 .....................................................................................................................................118 Figure 9.26: Global Neurodegenerative Disorder Therapeutics Market (Ebixa – Product Revenue), 2019-2030 .....................................................................................................................................119 Figure 9.27: Global Neurodegenerative Disorder Therapeutics Market (Namenda XR – Product Revenue), 2019-2030....................................................................................................................119 Figure 9.28: Global Neurodegenerative Disorder Therapeutics Market (Namzaric – Product Revenue), 2019-2030....................................................................................................................120 Figure 9.29: Global Neurodegenerative Disorder Therapeutics Market (Galantamine – Product Revenue), 2019-2030....................................................................................................................120 Figure 9.30: Global Neurodegenerative Disorder Therapeutics Market (Others – Product Revenue), 2019-2030 .....................................................................................................................................121 Figure 9.31: Global Neurodegenerative Disorder Therapeutics Market (Azilect – Product Revenue), 2019-2030 .....................................................................................................................................122 Figure 9.32: Global Neurodegenerative Disorder Therapeutics Market (Neupro – Product Revenue), 2019-2030 .....................................................................................................................................122 Figure 9.33: Global Neurodegenerative Disorder Therapeutics Market (Madopar – Product Revenue), 2019-2030 .....................................................................................................................................123 Figure 9.34: Global Neurodegenerative Disorder Therapeutics Market (Duopa – Product Revenue), 2019-2030 .....................................................................................................................................123 Figure 9.35: Global Neurodegenerative Disorder Therapeutics Market (Inbrija – Product Revenue), 2019-2030 .....................................................................................................................................124 Figure 9.36: Global Neurodegenerative Disorder Therapeutics Market (Others – Product Revenue), 2019-2030 .....................................................................................................................................124 Figure 9.37: Global Neurodegenerative Disorder Therapeutics Market (Spinraza – Product Revenue), 2019-2030 .....................................................................................................................................125
  • 19. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 19 Figure 9.38: Global Neurodegenerative Disorder Therapeutics Market (Zolgensma – Product Revenue), 2019-2030....................................................................................................................126 Figure 9.39: Global Neurodegenerative Disorder Therapeutics Market (Others – Product Revenue), 2019-2030 .....................................................................................................................................126 Figure 9.40: Global Neurodegenerative Disorder Therapeutics Market (Austedo – Product Revenue),2019-2030.....................................................................................................................127 Figure 9.41: Global Neurodegenerative Disorder Therapeutics Market (Xenazine – Product Revenue),2019-2030.....................................................................................................................128 Figure 9.42: Global Neurodegenerative Disorder Therapeutics Market (Others – Product Revenue), 2019-2030 .....................................................................................................................................128 Figure 9.43: Global Neurodegenerative Disorder Therapeutics Market (Zeposia Expected Launch - 2020), 2019-2030 ..........................................................................................................................129 Figure 9.44: Global Neurodegenerative Disorder Therapeutics Market (Ponesimod Expected Launch - 2020), 2019-2030 ........................................................................................................................129 Figure 9.45: Global Neurodegenerative Disorder Therapeutics Market (Ofatumumab Expected Launch 2021), 2019-2030..............................................................................................................130 Figure 9.46: Global Neurodegenerative Disorder Therapeutics Market (Ublituximab Expected Launch - 2021), 2019-2030 ........................................................................................................................130 Figure 9.47: Global Neurodegenerative Disorder Therapeutics Market (Ibudilast Expected Launch - 2022), 2019-2030 ..........................................................................................................................131 Figure 9.48: Global Neurodegenerative Disorder Therapeutics Market (SAR442168 Expected Launch - 2026), 2019-2030 ........................................................................................................................131 Figure 9.49: Global Neurodegenerative Disorder Therapeutics Market (Tricaprilin Expected Launch - 2023), 2019-2030 ..........................................................................................................................132 Figure 9.50: Global Neurodegenerative Disorder Therapeutics Market (Bryostatin-1 Expected Launch - 2025), 2019-2030 ........................................................................................................................132 Figure 9.51: Global Neurodegenerative Disorder Therapeutics Market (AGB101 Expected Launch - 2025), 2019-2030 ..........................................................................................................................133 Figure 9.52: Global Neurodegenerative Disorder Therapeutics Market (COR388 Expected Launch - 2023), 2019-2030 ..........................................................................................................................133
  • 20. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 20 Figure 9.53: Global Neurodegenerative Disorder Therapeutics Market (TRx0237 Expected Launch - 2024), 2019-2030 ..........................................................................................................................134 Figure 9.54: Global Neurodegenerative Disorder Therapeutics Market (Brexpiprazole Expected Launch - 2023), 2019-2030............................................................................................................134 Figure 9.55: Global Neurodegenerative Disorder Therapeutics Market (Semorinemab Expected Launch - 2024), 2019-2030............................................................................................................135 Figure 9.56: Global Neurodegenerative Disorder Therapeutics Market (Aducanumab Expected Launch - 2020), 2019-2030............................................................................................................135 Figure 9.57: Global Neurodegenerative Disorder Therapeutics Market (Eltoprazine Expected Launch - 2020), 2019-2030 ........................................................................................................................136 Figure 9.58: Global Neurodegenerative Disorder Therapeutics Market (Ongentys Expected Launch - 2020), 2019-2030 ..........................................................................................................................136 Figure 9.59: Global Neurodegenerative Disorder Therapeutics Market (IPX-066 Expected Launch - 2020), 2019-2030 ..........................................................................................................................137 Figure 9.60: Global Neurodegenerative Disorder Therapeutics Market (Xadago Expected Launch - 2020), 2019-2030 ..........................................................................................................................137 Figure 9.61: Global Neurodegenerative Disorder Therapeutics Market (Nourianz Expected Launch - 2020), 2019-2030 ..........................................................................................................................138 Figure 9.62: Global Neurodegenerative Disorder Therapeutics Market (Opicapone Expected Launch - 2020), 2019-2030 ........................................................................................................................138 Figure 9.63: Global Neurodegenerative Disorder Therapeutics Market (RG6042/IONIS -HTTrx Expected Launch - 2021), 2019-2030............................................................................................139 Figure 9.64: Global Neurodegenerative Disorder Therapeutics Market (WVE-120101 Expected Launch - 2022), 2019-2030............................................................................................................139 Figure 9.65: Global Neurodegenerative Disorder Therapeutics Market (WVE-120102 Expected Launch - 2022), 2019-2030............................................................................................................140 Figure 10.1: Revenue Contribution of Different Segments, 2019 and 2030...................................142 Figure 10.2: Global Neurodegenerative Disorder Therapeutics Market (by Immunomodulators), 2019- 2030...............................................................................................................................................143 Figure 10.3: Global Neurodegenerative Disorder Therapeutics Market (by Interferons), 2019-2030 .......................................................................................................................................................145
  • 21. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 21 Figure 10.4: Global Neurodegenerative Disorder Therapeutics Market (by Dopamine agonists), 2019- 2030...............................................................................................................................................146 Figure 10.5: Global Neurodegenerative Disorder Therapeutics Market (by Decarboxylase Inhibitors), 2019-2030 .....................................................................................................................................147 Figure 10.6: Global Neurodegenerative Disorder Therapeutics Market (by Others), 2019-2030 ...149 Figure 11.1: Global Neurodegenerative Disorder Therapeutics Market, by Indication ...................151 Figure 11.2: Global Neurodegenerative Disorder Therapeutics Market (by Indication), 2020 and 2030 .......................................................................................................................................................151 Figure 11.3: Global Neurodegenerative Disorder Therapeutics Market (by Multiple Sclerosis), 2019- 2030...............................................................................................................................................152 Figure 11.4: Global Neurodegenerative Disorder Therapeutics Market (by Epilepsy), 2019-2030.154 Figure 11.5: Global Neurodegenerative Disorder Therapeutics Market (by Spinal Muscular Atrophy), 2019-2030 .....................................................................................................................................155 Figure 11.6: Global Neurodegenerative Disorder Therapeutics Market (by Alzheimer’s disease), 2019-2030 .....................................................................................................................................156 Figure 11.7: Global Neurodegenerative Disorder Therapeutics Market (by Parkinson’s disease), 2019-2030 .....................................................................................................................................158 Figure 11.8: Global Neurodegenerative Disorder Therapeutics Market (by Huntington’s disease), 2019-2030 .....................................................................................................................................159 Figure 11.9: Global Neurodegenerative Disorder Therapeutics Market (by Other Neurological Disorders), 2019-2030...................................................................................................................160 Figure 12.1: Revenue Contribution of Different Segments, 2020 and 2030...................................161 Figure 12.2: Global Neurodegenerative Disorder Therapeutics Market (by Oral), 2019-2030 .......162 Figure 12.3: Global Neurodegenerative Disorder Therapeutics Market (by Injectable), 2019-2030 .......................................................................................................................................................163 Figure 12.4: Global Neurodegenerative Disorder Therapeutics Market (by Enteral), 2019-2030..164 Figure 12.5: Global Neurodegenerative Disorder Therapeutics Market (by Transdermal), 2019-2030 .......................................................................................................................................................165 Figure 12.6: Global Neurodegenerative Disorder Therapeutics Market (by Other RoA), 2019-2030 .......................................................................................................................................................166 Figure 13.1: Global Neurodegenerative Disorder Therapeutics Market (by Region)......................167
  • 22. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 22 Figure 13.2: Global Neurodegenerative Disorder Therapeutics Market (by Region), 2019-2030..168 Figure 13.3: North America Neurodegenerative Disorder Therapeutics Market, 2019-2030..........169 Figure 13.4: North America: Market Dynamics ..............................................................................170 Figure 13.5: Revenue Contributions of Different Countries in North America, 2019 and 2030......171 Figure 13.6: U.S. Neurodegenerative Disorder Therapeutics Market, 2019-2030 .........................173 Figure 13.7: U.S. Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 ..174 Figure 13.8: Canada Neurodegenerative Disorder Therapeutics Market, 2019-2030....................175 Figure 13.9: Canada Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 .......................................................................................................................................................176 Figure 13.10: Europe Neurodegenerative Disorder Therapeutics Market, 2019-2030...................178 Figure 13.11: Europe: Market Dynamics........................................................................................178 Figure 13.12: Revenue Contributions Different Countries in Europe, 2019 and 2030....................179 Figure 13.13: Germany Neurodegenerative Disorder Therapeutics Market, 2019-2030................180 Figure 13.14: Germany Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 .......................................................................................................................................................181 Figure 13.15: U.K. Neurodegenerative Disorder Therapeutics Market, 2019-2030 .......................182 Figure 13.16: U.K. Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 183 Figure 13.17: France Neurodegenerative Disorder Therapeutics Market, 2019-2030 ...................184 Figure 13.18: France Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 .......................................................................................................................................................185 Figure 13.19: Italy Neurodegenerative Disorder Therapeutics Market, 2019-2030........................186 Figure 13.20: Italy Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030.187 Figure 13.21: Spain Neurodegenerative Disorder Therapeutics Market, 2019-2030 .....................188 Figure 13.22: Spain Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 .......................................................................................................................................................189 Figure 13.23: Rest-of-Europe Neurodegenerative Disorder Therapeutics Market, 2019-2030 ......190 Figure 13.24: RoE Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 191 Figure 13.25: Asia-Pacific Neurodegenerative Disorder Therapeutics Market, 2019-2030............192 Figure 13.26: APAC: Market Dynamics .........................................................................................193 Figure 13.27: Revenue Contributions Different Countries in Asia-Pacific, 2019 and 2030.............194 Figure 13.28: China Neurodegenerative Disorder Therapeutics Market, 2019-2030.....................196
  • 23. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 23 Figure 13.29: China Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 .......................................................................................................................................................197 Figure 13.30: Japan Neurodegenerative Disorder Therapeutics Market, 2019-2030.....................198 Figure 13.31: Japan Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 .......................................................................................................................................................200 Figure 13.32: India Neurodegenerative Disorder Therapeutics Market, 2019-2030.......................201 Figure 13.33: India Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030202 Figure 13.34: South Korea Neurodegenerative Disorder Therapeutics Market, 2019-2030...........203 Figure 13.35: South Korea Neurodegenerative Disorder Therapeutics Market (by Indication), 2019- 2030...............................................................................................................................................204 Figure 13.36: Australia Neurodegenerative Disorder Therapeutics Market, 2019-2030.................205 Figure 13.37: Australia Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 .......................................................................................................................................................206 Figure 13.38: RoAPAC Neurodegenerative Disorder Therapeutics Market, 2019-2030................207 Figure 13.39: RoAPAC Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 .......................................................................................................................................................208 Figure 13.40: Latin America Neurodegenerative Disorder Therapeutics Market, 2019-2030.........210 Figure 13.41: Latin America Neurodegenerative Disorder Therapeutics Market (by Country), 2019- 2030...............................................................................................................................................210 Figure 13.42: Revenue Contributions Different Countries in Latin America, 2019 and 2030..........211 Figure 13.43: Brazil Neurodegenerative Disorder Therapeutics Market, 2019-2030......................212 Figure 13.44: Brazil Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 .......................................................................................................................................................213 Figure 13.45: Mexico Neurodegenerative Disorder Therapeutics Market, 2019-2030...................214 Figure 13.46: Mexico Neurodegenerative Disorder Therapeutics Market (by Indication), 2019-2030 .......................................................................................................................................................215 Figure 13.47: Rest-of-Latin America Neurodegenerative Disorder Therapeutics Market, 2019-2030 .......................................................................................................................................................216 Figure 13.48: RoLATAM Neurodegenerative Disorder Therapeutics Market (by Indication), 2019- 2030...............................................................................................................................................217 Figure 13.49: RoW Neurodegenerative disorder therapeutics market, 2019-2030 ........................218
  • 24. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 24 Figure 14.1: Share of Key Developments and Strategies, July 2015 - July 2020..........................220 Figure 14.2: Regulatory and Legal Developments Share (by Company), July 2015 - July 2020...221 Figure 14.3: Partnerships, Alliances, and Business Expansions (by Company), July 2015 - July 2020 .......................................................................................................................................................222 Figure 14.4: M&A Activities Share (by Company), July 2015 - July 2020 ......................................223 Figure 14.5: Market Share Analysis (by Companies), 2018 and 2019...........................................224 Figure 15.1: Total Number of Companies Profiled.........................................................................226 Figure 15.2: AbbVie Inc.: Overall Product Portfolio........................................................................228 Figure 15.3: AbbVie Inc.Overall Financials, 2017-2019.................................................................230 Figure 15.4: AbbVie Inc.: Revenue (by Region), 2017-2019..........................................................231 Figure 15.5: AbbVie Inc.: R&D Expenditure, 2017-2019................................................................232 Figure 15.6: AbbVie Inc.: SWOT Analysis .....................................................................................233 Figure 15.7: Bayer AG: Overall Product Portfolio...........................................................................235 Figure 15.8: Bayer AG: Overall Financials, 2017-2019..................................................................235 Figure 15.9: Bayer AG: Revenue (by Segment), 2018-2019 .........................................................236 Figure 15.10: Bayer AG: Revenue (by Region), 2017-2019 ..........................................................237 Figure 15.11: Bayer AG: R&D Expenditure, 2017-2019.................................................................237 Figure 15.12: Bayer AG: SWOT Analysis......................................................................................238 Figure 15.13: Biogen Inc.: Overall Service Portfolio.......................................................................240 Figure 15.14: Biogen Inc.: Overall Financials, 2017-2019..............................................................243 Figure 15.15: Biogen Inc.: Sales (by Product), 2017-2019.............................................................244 Figure 15.16: Biogen Inc.: Sales (by Region), 2017-2019..............................................................244 Figure 15.17: Biogen Inc.: R&D Expenditure, 2017-2019 ..............................................................245 Figure 15.18: Biogen Inc.: SWOT Analysis....................................................................................246 Figure 15.19: Bristol Myers Squibb Company: Overall Product Portfolio .......................................248 Figure 15.20: Bristol Myers Squibb Company: Overall Financials, 2017-2019 ..............................249 Figure 15.21: Bristol Myers Squibb Company: Revenue (by Region), 2017-2019.........................250 Figure 15.22: Bristol Myers Squibb Company: R&D Expenditure, 2017-2019...............................250 Figure 15.23: Bristol Myers Squibb Company: SWOT Analysis.....................................................251 Figure 15.24: C. H. Boehringer Sohn AG & Co. KG: Overall Product Portfolio..............................253 Figure 15.25: C. H. Boehringer Sohn AG & Co. KG: Overall Financials, 2017-2019 .....................254
  • 25. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 25 Figure 15.26: C. H. Boehringer Sohn AG & Co. KG: Revenue (by Segment), 2017-2019.............255 Figure 15.27: C. H. Boehringer Sohn AG & Co. KG: Revenue (by Region), 2017-2019................255 Figure 15.28: C. H. Boehringer Sohn AG & Co. KG: R&D Expenditure, 2017-2019......................256 Figure 15.29: C. H. Boehringer Sohn AG & Co. KG: SWOT Analysis............................................257 Figure 15.30: Eisai Inc.: Overall Product Portfolio..........................................................................259 Figure 15.31: Eisai Inc.: Overall Financials, 2017-2019.................................................................261 Figure 15.32: Eisai Inc.: Revenue (by Segment), 2017-2019.........................................................262 Figure 15.33: Eisai Inc.: Revenue (by Region), 2017-2019............................................................263 Figure 15.34: Eisai Inc.: R&D Expenditure, 2017-2019..................................................................264 Figure 15.35: Eisai Inc.: SWOT Analysis .......................................................................................265 Figure 15.36: F. Hoffmann-La Roche Ltd: Product Portfolio ..........................................................267 Figure 15.37: F. Hoffmann-La Roche Ltd: Overall Financials, 2017-2019 .....................................269 Figure 15.38: F. Hoffmann-La Roche Ltd: Revenue (by Segment), 2017-2019.............................270 Figure 15.39: F. Hoffmann-La Roche Ltd: Revenue (by Region), 2017-2019................................271 Figure 15.40: F. Hoffmann-La Roche Ltd: R&D Expenditure, 2017-2019......................................271 Figure 15.41: F. Hoffmann-La Roche Ltd: SWOT Analysis............................................................272 Figure 15.42: GlaxoSmithKline plc: Overall Product Portfolio ........................................................274 Figure 15.43: GlaxoSmithKline plc: Overall Financials, 2017-2019................................................275 Figure 15.44: GlaxoSmithKline plc: Revenue (by Segment), 2017-2019.......................................276 Figure 15.45: GlaxoSmithKline plc: Revenue (by Region), 2017-2019..........................................277 Figure 15.46: GlaxoSmithKline plc: R&D Expenditure, 2017-2019 ................................................278 Figure 15.47: GlaxoSmithKline plc: SWOT Analysis......................................................................279 Figure 15.48: H. Lundbeck A/S: Overall Product Portfolio .............................................................281 Figure 15.49: H. Lundbeck A/S: Overall Financials, 2017-2019.....................................................282 Figure 15.50: H. Lundbeck A/S: Revenue (by Segment), 2017-2019............................................283 Figure 15.51: H. Lundbeck A/S: Revenue (by Region), 2017-2019 ...............................................284 Figure 15.52: H. Lundbeck A/S: R&D Expenditure, 2017-2019 .....................................................284 Figure 15.53: H. Lundbeck A/S: SWOT Analysis...........................................................................285 Figure 15.54: Merck KGaA: Product Portfolio................................................................................287 Figure 15.55: Merck KGaA: Overall Financials, 2017-2019...........................................................288 Figure 15.56: Merck KGaA: Revenue (by Segment), 2017-2019...................................................289
  • 26. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 26 Figure 15.57: Merck KGaA: Revenue (by Region), 2017-2019......................................................290 Figure 15.58: Merck KGaA: R&D Expenditure, 2017-2019............................................................290 Figure 15.59: Merck KGaA: SWOT Analysis .................................................................................291 Figure 15.60: Novartis AG: Overall Financials, 2017-2019 ............................................................294 Figure 15.61: Novartis AG Net Revenue (by Business Segment), 2017-2019...............................295 Figure 15.62: Novartis AG: Net Revenue (by Region), 2017-2019 ................................................296 Figure 15.63: Novartis AG: R& D Expense, 2017-2019.................................................................296 Figure 15.64: Novartis AG: SWOT Analysis ..................................................................................297 Figure 15.65: Pfizer Inc.: Overall Product Portfolio ........................................................................299 Figure 15.66: Pfizer Inc.: Overall Financials, 2017-2019................................................................300 Figure 15.67: Pfizer Inc.: Revenue (by Segment), 2017-2019 .......................................................301 Figure 15.68: Pfizer Inc.: Revenue Split (by Biopharma Segment), 2017-2019.............................301 Figure 15.69: Pfizer Inc.: Revenue (by Region), 2017-2019 ..........................................................302 Figure 15.70: Pfizer Inc: R&D Expenditure, 2017-2019 .................................................................303 Figure 15.71: Pfizer Inc.: SWOT Analysis......................................................................................304 Figure 15.72: Sanofi SA: Overall Product Portfolio ........................................................................306 .......................................................................................................................................................306 Figure 15.73: Sanofi SA: Overall Financials, 2017-2019................................................................308 Figure 15.74: Sanofi SA: Revenue (by Segment), 2017-2019.......................................................309 Figure 15.75: Sanofi SA: Revenue (by Region), 2017-2019..........................................................309 Figure 15.76: Sanofi SA: R&D Expenditure, 2017-2019 ................................................................310 Figure 15.77: Sanofi SA: SWOT Analysis......................................................................................311 Figure 15.78: Teva Pharmaceutical Industries Ltd.: Overall Product Offerings for Global Neurodegenerative Disorder Therapeutics Market ........................................................................313 Figure 15.79: Teva Pharmaceutical Industries Ltd.: Overall Financials, 2017-2019.......................314 Figure 15.80: Teva Pharmaceutical Industries Ltd.: Net Revenue (by Business Segment), 2017-2019 .......................................................................................................................................................315 Figure 15.81: Teva Pharmaceutical Industries Ltd.: Research and Development Expense, 2017-2019 .......................................................................................................................................................316 Figure 15.82: Teva Pharmaceutical Industries Ltd.: SWOT Analysis.............................................317 Figure 15.83: UCB Pharma SA: Overall Product Portfolio .............................................................319
  • 27. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 27 Figure 15.84: UCB Pharma SA: Overall Financials, 2017-2019.....................................................320 Figure 15.85: UCB Pharma SA: Revenue (by Product), 2017-2019..............................................321 Figure 15.86: UCB Pharma SA: Revenue (by Region), 2017-2019...............................................322 Figure 15.87: UCB Pharma SA: R&D Expenditure, 2017-2019 .....................................................322 Figure 15.88: UCB Pharma SA: SWOT Analysis...........................................................................323
  • 28. Global Neurodegenerative Disorder Therapeutics Market All rights reserved at BIS Research 28 List of Tables Table 1: Leading Players in Global Neurodegenerative Disorder Therapeutics Market...................35 Table 4.1: Comparison of Drug Development Within and Outside the Central Nervous System .....54 Table 4.2: Commercialized Neurodegenerative Disorders Therapeutic Products............................55 Table 8.1: Regulatory Scenario Across the World ...........................................................................85 Table 8.2: Expedited Regulatory Designations Around the World ...................................................98 Table 8.3: Current Regulatory Development Guidelines for Neurodegenerative Disorders ...........101 Table 15.1: AbbVie Inc.: Pipeline Product Portfolio........................................................................230 Table 15.2: Biogen Inc.: Pipeline Product Portfolio ........................................................................242 Table 15.3: Bristol Myers Squibb Company: Pipeline Product Portfolio.........................................249 Table 15.4: C. H. Boehringer Sohn AG & Co. KG Company: Pipeline Product Portfolio................254 Table 15.5: C. H. Boehringer Sohn AG & Co. KG Company: Pipeline Product Portfolio................261 Table 15.6: F. Hoffmann-La Roche Ltd.: Pipeline Product Portfolio...............................................268 Table 15.7: H. Lundbeck A/S Company: Pipeline Product Portfolio...............................................283 Table 15.8: Merck KGaA: Pipeline Product Portfolio......................................................................288 Table 15.9: Novartis AG: Pipeline Product Portfolio.......................................................................294 Table 15.10: Pfizer Plc: Pipeline Product Portfolio.........................................................................300 Table 15.11: Sanofi SA: Pipeline Product Portfolio........................................................................307 Table 15.12: Teva Pharmaceutical Industries Ltd Company: Pipeline Product Portfolio................315 Table 15.13: UCB Pharma SA Company: Pipeline Product Portfolio.............................................321
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