Asthma and coagulatıon
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Akademik Solunum Derneği Budva-Montenegro.21-24 September 2017- 2.Eurolasian Respiratory Allergy
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Asthma and coagulatıon
- 10. EXTRINSIC PATHWAY OF COAGULATION IS ACTIVATED IN RESPONSE TO HIGH LEVEL OF CIRCULATORY IGE.
- 12. Best example of this purported relationship is the correlation between higher TF expression and vasculitis degree that has been seen in Hyper IgE Syndrome.
- 20. Yalcin AD.The relation of sTRAIL levels and quality of life in severe persistent allergic asthma patients using omalizumab.Med Sci Monit. 2012 Aug;18(8):9- 10.
- 36. D-DIMER LEVELS DECREASED IN SEVERE ALLERGIC ASTHMA AND CHRONIC URTICARIA PATIENTS WITH THE OMALIZUMAB TREATMENT. YALÇIN ARZU DIDEM,ÇELIK BETÜL,GÜMÜSLÜ SAADET (2014). D-Dimer Levels Decreased in Severe Allergic Asthma and Chronic Urticaria Patients with the Omalizumab Treatment. Expert Opinion on Biological Therapy, 14(3), 283-286., Doi: 10.1517/14712598.2014.875525 Mediators and cells classically involved in procoagulant and anticoagulant pathways altogether play a role in SPA and CU pathophysiology and omalizumab effect.
- 37. Figure 1: (Group I:SPA, n:20) D-Dimer levels (mean±SD). Group IA: 467.63±106.39. Group IB: 430.00 ± 92.90. Group IC: 401.21 ± 72.19. Group ID: 377.37 ± 62.33. Group IA, using desloratadin, inhalan forte doses steroid .We compared DD levels between groups: The significant DD difference was observed between group-IA and group-IC (p<0.05), (P=0.031); between group-IA and group-ID (p<0.05), (P=0.003); between group-IB and group-ID (p<0.05), (P=0.049); a significant positive correlation between age and ADY (p=0.043, r=0.468, p<0.05). In the group-ID there was a significant positive correlation between DD and age (p=0.034, r=0.488, p<0.05).
- 38. e 2: (Group II: CU, n:8) D-Dimer levels (mean±SD). Group IIA-1: 506.25 ± 133.93. Group IIA-2 : 437.75 ± 54.83. Group IIB: 408.00 ± 125.39. Group IIC: 377.38 ± 104.50. Group IID: 350.87 ± 70.60. Group IIA-2 consisted of patients whose lesions were passive stage. Omalizumab was given to group IIB and IIC (225- 375 MG) and gradually was ceased and continued with desloratadin 1x1. Group IID patients were under omalizumab medication only. The significant DD difference was observed between Group IIA-1 and Group- IID (p<0.05), (P=0.015). In the IIA-1 group there was a significant positive correlation between DD and age (p=0.008, r=0.848, p<0.005).
- 39. Expert in Biol Ther 2013;13(9):1335-41.