its is a dialysis treatmet educstion

1. cytosorbents
cytosorb
CytoSorb® is an extracorporeal blood purification therapy designed to reduce excessive levels
of inflammatory mediators such as cytokines, or “cytokine storm”, from blood . the goal is to
reduce the potentially deadly systemic inflammatory response syndrome (SIRS) seen in life-
threatening inflammatory conditions. Use of the therapy may help to mitigate or even avoid
deadly complications such as organ failure in this hyper-inflammatory response, helping to
stabilize patients and reduce the severity of illness
In sepsis, one of the largest indications for CytoSorb, antibiotics are used to control the
primary infection, while concurrent use of CytoSorb is designed to help control the excessive
inflammatory response, remove certain bacterial toxins, and avoid cell-mediated injury to
otherwise healthy organs.
The CytoSorb adsorber is a standard whole blood perfusion cartridge that can be used with
conventional hemodialysis machines, hemoperfusion machines, heart-lung machines, and as
stand-alone therapy with many other kinds of blood pumps. It takes only minutes to set-up, and
can be used by itself or in series with a standard hemodialyzer or hemofilter.
Treatment goals: CytoSorb therapy is intended to improve patient outcomes by:
Improving hemodynamic stability with a reduction in the use of vasopressors
Reducing capillary leak syndrome with a reversal of the fluid balance
Removing a wide variety of inflammatory mediators that can destabilize the patient
Preventing or treating multiple organ failure
CytoSorb is currently being used to treat patients in the intensive care unit (ICU) and during
surgery

2. Applications in the ICU (using a dialysis machine):
Severe sepsis/septic shock
Toxin-mediated infections such as toxic shock syndrome, enterohaemorrhagic E. coli infection,
and necrotizing fasciitis
Acute respiratory distress syndrome and acute lung injury
Severe SIRS after cardiac surgery with cardiopulmonary bypass (CPB)
Polytrauma with severe rhabdomyolysis
Severe acute pancreatitis
Liver failure of varying etiologies
Severe burn injury
Severe influenza, with or without ECMO
Cardiogenic shock
Post-cardiopulmonary resuscitation

3. And others
Intra-operative applications in cardiothoracic surgery (using a heart-lung machine):
Surgical procedures with long cardiopulmonary bypass (CPB) times (>120min)
Patients with an increased risk during complex combination surgeries or reinterventions
Patients with risk factors such as
– Endocarditis
– Liver dysfunction
– Aortic dissection
Implantation of an LVAD (left ventricular assist device)
Patients undergoing heart – lung transplantation