DRUG STUDY

1. DRUG NAME DOSAGE, ROUTE
& FREQUENCY
MECHANISM OF
ACTION
INDICATIONS CONTRAINDICA
TIONS
SIDE
EFFECTS/ADVER
SE EFFECTS
NURSING RESPONSI
BRAND
NAME:
Erceflora
GENERIC
NAME:
Bacillus clausii
CLASSIFICATI
ON:
Antidiarrheals
DOSAGE:
5ml/amp
ROUTE:
Per Orem
FREQUENCY:
Q4
Erceflora also
contains sterile
distilled water.
Adults
2-3 vials per day
Administration at
regular intervals (3-
4hours)
Children (2-11 years
old)
1-2 vials per day
Administration at
regular intervals (3-
4hrs)
Infants
1-2 vials
Administration at
regular intervals (3-4
hrs)
Erceflora is a
product that
contains the spores
of Bacillus clausii,
a type of bacteria
that is resistant to
antibiotics. It helps
replenish and
support the normal
flora of the gut.
Additionally, it is
considered a
probiotic.
Indications for
probiotics include
post-antibiotic use,
chronic diarrhea or
constipation, and
certain vitamin
malabsorption
disorders.
 Acute
diarrhea
with
duration ≤
14 days
due to
infection,
drugs or
poison.
 Chronic or
persistent
diarrhea
with
duration of
>14days.
 Hypersen
sitivity to
B. calausii
or to any
of the
prodct
excipients
 Not for use
in
immunoco
mpromised
patients
(cancer
patients on
chemother
apy,
patients
taking
immunosup
pressant
meds)
SIDE EFFECT:
 BACILLUS
CLAUSII is
generally
safe and
does not
cause side
effects.
 rarely, it
may
cause gas,
bloating,
and
hypersensiti
vity
reactions
such as
rash,
angioedem
a, and
urticaria.
Talk to your
doctor if
you
experience
these side
effects.
ADVERSE
EFFECT:
 No adverse
effects were
INTERVENTION/EVAL
 Shake the drug
administration
 Use only a minim
for minimal perio
 Do not exceed i
recommended d
 Monitor the patie
unusual effects
drug
 Administer the d
within 30 minute
openin the
container/ampul
PATIENT/FAMILY TEA
 Educate the pat
family about the
and recommend
of the drug
 Educate the pat
family about the
side effects of th
medication
 Encourage fami
report unusual e
and changes of
patient’s conditio
administration

2. noted in
clinical trials
of B. clausii
or in the
product
information.
Casapao, Anna Marie C.
BSN 2-1
DRUG STUDY
Name of Drug Dosage/R
oute/
Frequenc
y
Mechani
sm of
Action
Indicat
ion
Contraindica
tions
Side
effect/Adv
erse
Effect
Drug
interact
ion
Special
Precauti
ons
Nursing
Responsibility
BRAND NAME:
Erceflora
GENERIC NAME:
Bacillus clausii
CLASSIFICATION:Anti
diarrheals
-Adults
2-3 vials per
day
Administrati
on at
regular
intervals (3-
4hours)
-Children
(2-11 years
old)
1-2 vials per
day
Administrati
on at
-
Erceflora
is a
product
that
contains
the
spores of
Bacillus
clausii, a
type of
bacteria
that is
resistant
to
antibiotics
-Acute
diarrhea
with
duration
≤ 14
days
due to
infectio
n, drugs
or
poison.
-
Chronic
or
persiste
·-
Hypersensitivit
y to B. calausii
or to any of the
prodct
excipients
-Not for use in
immunocompr
omised
patients
(cancer
patients on
chemotherapy,
patients taking
SIDE
EFFECT:
-BACILLUS
CLAUSII is
generally
safe and
does not
cause side
effects.
-However,
rarely, it
may cause
-No
known
drug
interactio
ns
subsequ
ent to the
concomit
ant use
of other
drugs.
-This
medicine
is for oral
use only.
Do not
inject or
administer
in any
other way.
Severe
anaphylac
tic
reactions,
such as
anaphylac
tic shock,
INTERVENTION/EVA
LUATION:
-Shake the drug before
administration
-Use only a minimal
dose for minimal
periods.
-Do not exceed its
recommended dose.

3. regular
intervals (3-
4hrs)
-Infants
1-2 vials
Administrati
on at
regular
intervals (3-
4 hrs)
. It helps
replenish
and
support
the
normal
flora of
the gut.
Additional
ly, it is
considere
d a
probiotic.
Indication
s for
probiotics
include
post-
antibiotic
use,
chronic
diarrhea
or
constipati
on, and
certain
vitamin
malabsor
ption
disorders.
nt
diarrhea
with a
duration
of
>14day
s.
immunosuppre
ssant meds)
gas,
bloating,
and
hypersensiti
vity
reactions
such as
rash,
angioedem
a, and
urticaria.
Talk to your
doctor if
you
experience
these side
effects.
ADVERSE
EFFECT:
-No
adverse
effects
were noted
in clinical
trials of B.
clausii or in
the product
information.
have
occurred
with
incorrect
route of
administra
tion.
-
Precautio
ns for
use:
During
treatment
with
antibiotics,
the
medicinal
product
should be
used
during the
interval
between 2
administra
tions of
antibiotics.
-Monitor the patient for
unusual effects from
the drug
-Administer the drug
within 30 minutes after
opening the
container/ampule
PATIENT/FAMILY
TEACHING:
-Educate the patient
and family about the
uses and
recommended dose of
the drug
-Educate the patient
and family about the
possible side effects of
the medication
-Encourage family to
report unusual effects
and changes of the
patient’s condition
upon administration