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Postpartum Haemorrhage
Definitions
• Primary PPH – blood loss of 500ml or more
within 24hours of delivery.
• Secondary PPH – significant blood loss
between 24 hours and 6
weeks after birth.
Why do we care?
Major obstetric haemorrhage – more than
1000ml
Very rapidly lead to maternal death
• 3rd highest cause of direct maternal death in
the UK and Ireland (2003-2005)
• 58% of these cases care was “seriously
substandard”
• Major cause of severe maternal morbidity in
“near-miss audits”
Risk Factors
Most cases have no risk factors
• Previous PPH
• Antepartum haemorrhage
• Grand multiparity
• Multiple pregnancy
• Polyhydramnios
• Fibroids
• Placenta praevia
• Prolonged labour (&oxytocin)
Prevention
• Be aware of risk factors – may present antenatally
or intrapartum
• Treat anaemia antenatally
• Active management of the 3rd stage
• Prophylactic oxytocics reduce the risk of PPH by
60% (oxytocin or oxytocin & ergometrine)
• 5IU IM for vaginal delivery
• 5IU IV for LSCS
• Consider oxytocin infusions
4 T’s
Tone
Tissue
Thrombin
Trauma
Causes
Tone
Previous PPH
Prolonged labour
Age > 40 years
Big baby
Multiple pregnancy
Placenta praevia
Obesity
Asian ethnicity
Tissue
Retained placenta/
membrane/clot
Thrombin
Abruption
PET
Pyrexia
Intrauterine death
Amniotic fluid embolism
DIC
Trauma
Caesarean section
(emergency > elective)
Perineal trauma
Operative delivery
Vaginal and cervical tears
Uterine rupture
• Blood loss is commonly underestimated
• Loss may be well-tolerated
• Beware the “trickle” and the “moderate
lochia”
• Minor PPH can easily progress to major PPH.
Management
• Has the placenta been delivered and is it
complete?
• Is the uterus well-contracted?
• Is the bleeding due to trauma?
Resuscitation
A & B – 10 -15l/min O2 by facemask
C - 2 14 gauge cannulae
blood for Hb, U&E, LFTs, clotting
crossmatch 4 units
2 litres of crystalloid rapidly
transfuse as soon as possible – consider O –
ve blood if any delays.
Uterine Contraction-First Line Drugs
• Oxytocin 5IU
• Oxtocin infusion – 40IU in 500mls
• Ergometrine 0.5mg
• Carboprost (Haemabate©) 0.25mg IM every
15 minutes x 8 doses
• Misoprostol 600 mcg sublingually
Uterine Contraction – non-pharm
• Empty uterus
• Foley catheter
• Rub up a contraction
• Bimanual compression
• Balloon tamponade
• Brace suture
• Uterine artery ligation
• Internal iliac artery ligation
• Interventional radiology
• Hysterectomy – before it’s too late
B-Lynch Suture
Balloon Tamponade
Haematological Management
DIC
• Transfuse without delay
• Involve haematology service at an early stage
• Correct coagulopathy
• Liase with consultant haematologist re use of
recombinant Factor V11 (Novoseven©) and
Fibrinogen.
• Traumatic for patient, family and staff.
• Debriefing for patient and staff.
• Case analysed to ensure care was of good
standard and any substandard care can be
improved.
Secondary PPH
• Infection
• Retained placenta
• Trophoblastic disease
• Antibiotics
• Evacuation of retained products if bleeding
persistent or significant amount of tissue
retained.

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Postpartum-Haemorrhage 2 slides.ppt

  • 2. Definitions • Primary PPH – blood loss of 500ml or more within 24hours of delivery. • Secondary PPH – significant blood loss between 24 hours and 6 weeks after birth.
  • 3. Why do we care? Major obstetric haemorrhage – more than 1000ml Very rapidly lead to maternal death
  • 4. • 3rd highest cause of direct maternal death in the UK and Ireland (2003-2005) • 58% of these cases care was “seriously substandard” • Major cause of severe maternal morbidity in “near-miss audits”
  • 5. Risk Factors Most cases have no risk factors • Previous PPH • Antepartum haemorrhage • Grand multiparity • Multiple pregnancy • Polyhydramnios • Fibroids • Placenta praevia • Prolonged labour (&oxytocin)
  • 6. Prevention • Be aware of risk factors – may present antenatally or intrapartum • Treat anaemia antenatally • Active management of the 3rd stage • Prophylactic oxytocics reduce the risk of PPH by 60% (oxytocin or oxytocin & ergometrine) • 5IU IM for vaginal delivery • 5IU IV for LSCS • Consider oxytocin infusions
  • 8. Causes Tone Previous PPH Prolonged labour Age > 40 years Big baby Multiple pregnancy Placenta praevia Obesity Asian ethnicity Tissue Retained placenta/ membrane/clot
  • 9. Thrombin Abruption PET Pyrexia Intrauterine death Amniotic fluid embolism DIC Trauma Caesarean section (emergency > elective) Perineal trauma Operative delivery Vaginal and cervical tears Uterine rupture
  • 10. • Blood loss is commonly underestimated • Loss may be well-tolerated • Beware the “trickle” and the “moderate lochia” • Minor PPH can easily progress to major PPH.
  • 11. Management • Has the placenta been delivered and is it complete? • Is the uterus well-contracted? • Is the bleeding due to trauma?
  • 12. Resuscitation A & B – 10 -15l/min O2 by facemask C - 2 14 gauge cannulae blood for Hb, U&E, LFTs, clotting crossmatch 4 units 2 litres of crystalloid rapidly transfuse as soon as possible – consider O – ve blood if any delays.
  • 13. Uterine Contraction-First Line Drugs • Oxytocin 5IU • Oxtocin infusion – 40IU in 500mls • Ergometrine 0.5mg • Carboprost (Haemabate©) 0.25mg IM every 15 minutes x 8 doses • Misoprostol 600 mcg sublingually
  • 14. Uterine Contraction – non-pharm • Empty uterus • Foley catheter • Rub up a contraction • Bimanual compression • Balloon tamponade • Brace suture • Uterine artery ligation • Internal iliac artery ligation • Interventional radiology
  • 15. • Hysterectomy – before it’s too late
  • 16.
  • 19. Haematological Management DIC • Transfuse without delay • Involve haematology service at an early stage • Correct coagulopathy • Liase with consultant haematologist re use of recombinant Factor V11 (Novoseven©) and Fibrinogen.
  • 20. • Traumatic for patient, family and staff. • Debriefing for patient and staff. • Case analysed to ensure care was of good standard and any substandard care can be improved.
  • 21. Secondary PPH • Infection • Retained placenta • Trophoblastic disease • Antibiotics • Evacuation of retained products if bleeding persistent or significant amount of tissue retained.