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Approach to ADD- Acute
Diarrheal Disease in
children Dr Neminathan
CASE BASED DISCUSSIONS
Importance of diarrhea in Gen Practice
13% of our under five children die of diarrhea.
Rational approach to diarrhea is an interesting &
challenging exercise in day-to-day practice
Majority of ADD in children are benign and viral in
nature.
Diarrhea defn
Increase in the stool frequency &
liquidity that is considered abnormal
by the mother
Acute - < 14 days duration
Chronic - > 14 days duration
Practical EVENT 1
8yrs boy presents with severe abd pain, with
few loose stools & vomiting . No h/o
fever
Diagnosed as AGE , started with oral AB
Condition worsened , diagnosed as ACUTE
APPENDICITIS – operated as an EMERGENCY
EXPERIENCE GAINED 1
PATIENT HEARING A MUST
 Respect chief complaints
 Remember that mother can pick up even a minute
change in physiology of the child – GIVE DUE
RESPECT TO MOTHERS WORDS
Practical EVENT 2
These are three children presenting with following
complaints
1-Vomiting followed by diarrhea with fever
2-few loose stools ,persistant vomiting ,fever
3-sudden onset highgrade fever,diarrhea vomit
EXPERIENCE GAINED 2
Give importance to CHRONOLOGY OF EVENTS
1-Vomiting followed by diarrhea with fever =
AGE
2-few loose stools ,persistant vomiting ,fever =
UTI
3-sudden onset highgrade fever,diarrhea vomit =
VIRAL FEVER
Practical EVENT 3
1month old infant with loose stools of 20 days
Seen by multiple drs
Solely breast fed, well thriving, active & happy
child
Stool culture grew E Coli sensitive to all Abs
As he continued to have persistent loose stools in
spite of AB, he was referred to our institution
EXPERIENCE GAINED 3
Do not ignore clinical setting
Clinical setting of purely breast fed
well thriving , active child rules out infectious
etiology.
Does not need any investigations or treatment
Practical EVENT 4
6 months old presented with diarrhea of 3 days
duration – received symptomatic treatment –
DIARRHEA SETTLED ABRUPTLY – parents were
happy ,though the child was irritable.
Over the next few hours, vomiting,
abdominal distention , drowsy child symptoms
attributed to cry – aerophagy
Referred for inconsolable cry – o/e banana shaped
mass – Abd USG - INTUSSUSEPTION
EXPERIENCE GAINED 4
SUDDEN IMPROVEMENT may be OMINOUS
SUDDEN ABRUPT IMPROVEMENT is rare in clinical
practice
It must be considered as a sign of complication
Sequence of recovery is important ,if not so needs
close periodic observation in anticipation.
Practical EVENT 5
This is 2 month old with fresh blood in stools from
15th day of life
Happy play full well thriving solely breast fed
Diagnosing as bacterial dysentery , oral walamycin
was started, as there was no response IV amikacin
was started, as there was no clinical improvement a
trail of metronidazole was given , finally breast
feeding was stopped and started on soya milk
EXPERIENCE GAINED 5 ALL
BLOODY STOOLS are not DYSENTRY
Its irrational to start on empirical colistin
Avoid routine amikacin & metronidazole
Simple guidance to mother to stop cows milk
would have solved the issue
Practical EVENT 6
5 yrs old child with sudden onset watery diarrhea ,
skin rash and dry cough of 1day duration .
Child was prescribed with ORS and sent home
Practical EVENT 6
Visited second dr , as the episodes of stools didn’t
improve , as the parents were very concerned and
insisting on medicine to stop diarrhea, dr
prescribed racecatodril – diarrhea stopped –
parents happy –
after 2 days went third dr for abdominal distension
& diagnosed PARALYTIC ILEUS – parents unhappy
with previous dr
EXPERINCE GAINED 6 AVOID
ANTIMOTILITY DRUGS
Anti motility drugs like Lomotil, lopremide may cause
dread full complications - PARALYTIC ILEUS &
TOXIC MEGACOLON
Be rational –follow WHO PROTOCOL– ORS & ZINC

Practical EVENT 7
5 years old child with sudden fever vomiting few
loose stools of 3 days
Wise GP Started with paracetamol & ORS as per
protocol , patient got neighbor advice & gave
ibuprofen , later gave self medication with
mefenamic acid as per advice from internet .
Fever disappeared on day 5 , abdominal pain
appeared
EXPERIENCE GAINED 7
DENGUE CAN PRESENT LIKE ADD
Keep dengue in the back of mind – now its
hyperendemic
All that BEGINS with DIAARHEA does not END with
ADD
EXPERIENCE GAINED 8
GUESSING BY EXPERIENCE
Clinical clues –
Watery diarrhea – smallgut pathology – viral
Mucoid diarrhea –largegut pathology - bacteria
EXPERIENCE GAINED 8
GUESSING BY EXPERIENCE
Infant with watery diarrhea vomiting mod fever-
Rota
Older pre school child same presentation –
norwalks agent
Child with large watery stools vomiting severe
dehydration – ET Ecoli , cholera
Blood & mucous, fever, abd cramps & tenesmus –
Shigella
Practical EVENT 9
12 yrs old boy from kolikode immunized for age,
presented with high grade fever , tachycardia ,
muffled heart sound – clinically diagnosed of
myocarditis – started on IVIG .On the next day
developed bloody stools, his sibling had similar
stools. Vitals stable ,altered sensorium ,CBC
leucocytosis, started on CIPRO. Stool culture grew
shigella sonnie sensitive to cipro, but clinically failed
to respond , started developing seizures and he
succumbed
EXPERIENCE GAINED 9 NEVER
UNDERESTIMATE SHIGELLA
Never start on cipro for dysentery – high resistance
Shigella can cause death due to lethal toxic
enchelopathy- ekiri syndrome
Never under estimate SHIGELLA
Practical EVENT 10
3 days old neonate taken to gynec for vomiting
Well looking baby ,anicteric, feeding well – thought
to have mucous gastritis – reassured – sent home
Returned back with persistent symptoms –
prescribed – domperidone drops
Shrewd grand mother showed the color of vomitus –
green – gyn referred to pediatrician
EXPERENCE GAINED 10 DIAGNOSIS
WRITTEN ON THE FACE
Bilious vomiting in neonate INTESTIONAL
OBSTRUCTION until proven otherwise
Rope in ped surgeon urgently
CARRY HOME MESSAGES
Switch back to NORMAL pre diarrheal diet as
early as possible – include PREBIOTIC foods –
breast milk, curd, banana
Counseling DANGER SIGNS is a very important
component of management – mother should be
thought when to report back .
CARRY HOME MESSAGES
Keep watch full eye & look for Electrolyte
imbalance – improperly diluted ORS is the
commonest cause hypernatremic dehydration –
take time & educate mothers
Vast majority are viral – avoid routine ABs
In bacterial ADD -cefixime 8mg/kg/day-BD
Parasitic diarrhea(giardia&amoebiasis) rare
CARRY HOME MESSAGES
Primery lactose intolerance rare - never
stop BREAST MILK Avoid
COMBO DRUGS – norflox+ metro , oflox+orni
Avoid ANTIMOTILITY AGENTS
For all ADD only WHO RED ORS & ZINC
No role for probiotics
FAQs – Cough
Avoid cough syrup in less than 2 years
Avoid polypharmacy in cough syrup
Common cold –1st gen AH diphenhydramine
5mg/kg/day – 6 hrly
Isolated dry cough –
dextromethorphan 1-2mg/kg/day-8hrly
Allergic rhinitis & post nasal drib cough school
going – 2nd gen AH
FAQs – Cough
Chronic afebrile dry nocturnal cough –
short acting B2 agonist salbutamol 0.1-
0.4mg/kg/dose 8hrly
Chronic wet cough – PROTRACTED
BACTERIAL BRONCHITIS – Amoxicillin
+ clavulanic acid
Honey
Good demulcent effect , antioxidant , increased
cytokine release , excellent safety profile
Recommended by WHO
Dose – 2.5 ml to 5 ml HS with warm water
Not for children bellow 1 year - botulism
Ideal to use pasteurized honey
Dr .Neminathan, 9842211179
Consultant pediatrician
Coimbatore child trust hospital

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Approach to ADD- Acute Diarrheal Disease in children.pptx

  • 1. Approach to ADD- Acute Diarrheal Disease in children Dr Neminathan CASE BASED DISCUSSIONS
  • 2. Importance of diarrhea in Gen Practice 13% of our under five children die of diarrhea. Rational approach to diarrhea is an interesting & challenging exercise in day-to-day practice Majority of ADD in children are benign and viral in nature.
  • 3. Diarrhea defn Increase in the stool frequency & liquidity that is considered abnormal by the mother Acute - < 14 days duration Chronic - > 14 days duration
  • 4. Practical EVENT 1 8yrs boy presents with severe abd pain, with few loose stools & vomiting . No h/o fever Diagnosed as AGE , started with oral AB Condition worsened , diagnosed as ACUTE APPENDICITIS – operated as an EMERGENCY
  • 5. EXPERIENCE GAINED 1 PATIENT HEARING A MUST  Respect chief complaints  Remember that mother can pick up even a minute change in physiology of the child – GIVE DUE RESPECT TO MOTHERS WORDS
  • 6. Practical EVENT 2 These are three children presenting with following complaints 1-Vomiting followed by diarrhea with fever 2-few loose stools ,persistant vomiting ,fever 3-sudden onset highgrade fever,diarrhea vomit
  • 7. EXPERIENCE GAINED 2 Give importance to CHRONOLOGY OF EVENTS 1-Vomiting followed by diarrhea with fever = AGE 2-few loose stools ,persistant vomiting ,fever = UTI 3-sudden onset highgrade fever,diarrhea vomit = VIRAL FEVER
  • 8. Practical EVENT 3 1month old infant with loose stools of 20 days Seen by multiple drs Solely breast fed, well thriving, active & happy child Stool culture grew E Coli sensitive to all Abs As he continued to have persistent loose stools in spite of AB, he was referred to our institution
  • 9. EXPERIENCE GAINED 3 Do not ignore clinical setting Clinical setting of purely breast fed well thriving , active child rules out infectious etiology. Does not need any investigations or treatment
  • 10. Practical EVENT 4 6 months old presented with diarrhea of 3 days duration – received symptomatic treatment – DIARRHEA SETTLED ABRUPTLY – parents were happy ,though the child was irritable. Over the next few hours, vomiting, abdominal distention , drowsy child symptoms attributed to cry – aerophagy Referred for inconsolable cry – o/e banana shaped mass – Abd USG - INTUSSUSEPTION
  • 11. EXPERIENCE GAINED 4 SUDDEN IMPROVEMENT may be OMINOUS SUDDEN ABRUPT IMPROVEMENT is rare in clinical practice It must be considered as a sign of complication Sequence of recovery is important ,if not so needs close periodic observation in anticipation.
  • 12. Practical EVENT 5 This is 2 month old with fresh blood in stools from 15th day of life Happy play full well thriving solely breast fed Diagnosing as bacterial dysentery , oral walamycin was started, as there was no response IV amikacin was started, as there was no clinical improvement a trail of metronidazole was given , finally breast feeding was stopped and started on soya milk
  • 13. EXPERIENCE GAINED 5 ALL BLOODY STOOLS are not DYSENTRY Its irrational to start on empirical colistin Avoid routine amikacin & metronidazole Simple guidance to mother to stop cows milk would have solved the issue
  • 14. Practical EVENT 6 5 yrs old child with sudden onset watery diarrhea , skin rash and dry cough of 1day duration . Child was prescribed with ORS and sent home
  • 15. Practical EVENT 6 Visited second dr , as the episodes of stools didn’t improve , as the parents were very concerned and insisting on medicine to stop diarrhea, dr prescribed racecatodril – diarrhea stopped – parents happy – after 2 days went third dr for abdominal distension & diagnosed PARALYTIC ILEUS – parents unhappy with previous dr
  • 16. EXPERINCE GAINED 6 AVOID ANTIMOTILITY DRUGS Anti motility drugs like Lomotil, lopremide may cause dread full complications - PARALYTIC ILEUS & TOXIC MEGACOLON Be rational –follow WHO PROTOCOL– ORS & ZINC 
  • 17. Practical EVENT 7 5 years old child with sudden fever vomiting few loose stools of 3 days Wise GP Started with paracetamol & ORS as per protocol , patient got neighbor advice & gave ibuprofen , later gave self medication with mefenamic acid as per advice from internet . Fever disappeared on day 5 , abdominal pain appeared
  • 18. EXPERIENCE GAINED 7 DENGUE CAN PRESENT LIKE ADD Keep dengue in the back of mind – now its hyperendemic All that BEGINS with DIAARHEA does not END with ADD
  • 19. EXPERIENCE GAINED 8 GUESSING BY EXPERIENCE Clinical clues – Watery diarrhea – smallgut pathology – viral Mucoid diarrhea –largegut pathology - bacteria
  • 20. EXPERIENCE GAINED 8 GUESSING BY EXPERIENCE Infant with watery diarrhea vomiting mod fever- Rota Older pre school child same presentation – norwalks agent Child with large watery stools vomiting severe dehydration – ET Ecoli , cholera Blood & mucous, fever, abd cramps & tenesmus – Shigella
  • 21. Practical EVENT 9 12 yrs old boy from kolikode immunized for age, presented with high grade fever , tachycardia , muffled heart sound – clinically diagnosed of myocarditis – started on IVIG .On the next day developed bloody stools, his sibling had similar stools. Vitals stable ,altered sensorium ,CBC leucocytosis, started on CIPRO. Stool culture grew shigella sonnie sensitive to cipro, but clinically failed to respond , started developing seizures and he succumbed
  • 22. EXPERIENCE GAINED 9 NEVER UNDERESTIMATE SHIGELLA Never start on cipro for dysentery – high resistance Shigella can cause death due to lethal toxic enchelopathy- ekiri syndrome Never under estimate SHIGELLA
  • 23. Practical EVENT 10 3 days old neonate taken to gynec for vomiting Well looking baby ,anicteric, feeding well – thought to have mucous gastritis – reassured – sent home Returned back with persistent symptoms – prescribed – domperidone drops Shrewd grand mother showed the color of vomitus – green – gyn referred to pediatrician
  • 24. EXPERENCE GAINED 10 DIAGNOSIS WRITTEN ON THE FACE Bilious vomiting in neonate INTESTIONAL OBSTRUCTION until proven otherwise Rope in ped surgeon urgently
  • 25. CARRY HOME MESSAGES Switch back to NORMAL pre diarrheal diet as early as possible – include PREBIOTIC foods – breast milk, curd, banana Counseling DANGER SIGNS is a very important component of management – mother should be thought when to report back .
  • 26. CARRY HOME MESSAGES Keep watch full eye & look for Electrolyte imbalance – improperly diluted ORS is the commonest cause hypernatremic dehydration – take time & educate mothers Vast majority are viral – avoid routine ABs In bacterial ADD -cefixime 8mg/kg/day-BD Parasitic diarrhea(giardia&amoebiasis) rare
  • 27. CARRY HOME MESSAGES Primery lactose intolerance rare - never stop BREAST MILK Avoid COMBO DRUGS – norflox+ metro , oflox+orni Avoid ANTIMOTILITY AGENTS For all ADD only WHO RED ORS & ZINC No role for probiotics
  • 28. FAQs – Cough Avoid cough syrup in less than 2 years Avoid polypharmacy in cough syrup Common cold –1st gen AH diphenhydramine 5mg/kg/day – 6 hrly Isolated dry cough – dextromethorphan 1-2mg/kg/day-8hrly Allergic rhinitis & post nasal drib cough school going – 2nd gen AH
  • 29. FAQs – Cough Chronic afebrile dry nocturnal cough – short acting B2 agonist salbutamol 0.1- 0.4mg/kg/dose 8hrly Chronic wet cough – PROTRACTED BACTERIAL BRONCHITIS – Amoxicillin + clavulanic acid
  • 30. Honey Good demulcent effect , antioxidant , increased cytokine release , excellent safety profile Recommended by WHO Dose – 2.5 ml to 5 ml HS with warm water Not for children bellow 1 year - botulism Ideal to use pasteurized honey
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  • 33. Dr .Neminathan, 9842211179 Consultant pediatrician Coimbatore child trust hospital