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Outbreak of Coronavirus2019-nCov
Fact Sheet #3
Information from: Dr. Cai Glushak, AXA Partners Chief Medical Officer and Dr. Alan Tan, AXA Partners Asia Region Medical Director
Situation
The World Health Organization (WHO) has declared Public Health
Emergency of International Concern (PHEIC) now that the 2019
Coronavirus has spread to multiple countries.
A recent outbreak of severe respiratory infection that originated
in Wuhan City in Hubei Province, China has now been traced to a
newly identified virus, named 2019-nCoV. It is classified as a
Coronavirus, which is in the same family of viruses that caused
the SARS and Middle East Respiratory Syndrome in previous
years, but it is not the same agent and has a different disease
severity profile. It is also different from all influenza viruses, A, B
and H1N1and other avian flu virus.
Source
The origin of the infection has been traced to a live animal and
seafood market in Wuhan City. While originally most victims came
from Wuhan City, within China secondary person-to-person
transmission is now clearly established.
Spread
It is now established that person-to-person spread of the virus is
possible, although this has been very limited outside of China.
Spread is primarily by respiratory contamination, but also thought to
be possible through droplets from surface contact. Hence hygiene
precautions should focus on avoidance of contamination through
coughing and sneezing as well as cleansing of surfaces,
contaminated clothing.
Clinical syndrome
Symptoms of the current illness are:
➢ Fever and
➢ Shortness of breath and/or
➢ Cough – usually a dry cough
➢ Less common:
o Runny nose
o Sneezing
o Diarrhea
Since these are very non-specific symptoms, criteria for suspecting
the syndrome also include recent presence in a high-risk area,
primarily Wuhan City, or close contact with someone who has been
in that location. If secondary spread becomes prevalent, suspicion
for Coronavirus infection may include those with no such history.
Complication and death
Most patients do not develop severe illness. A minority have severe
respiratory illness requiring intensive treatment and a small
percentage (thus far 3-4%) have died. It is as yet unknown how
prevalent the infection may be in patients with mild illness who have
not come to clinical attention.
Infectivity
The incubation period for the virus and duration the patient remains
contagious after illness is unknown. Based on prior Coronavirus
outbreaks, health authorities advise it may take up to 12 days before
an exposed person may develop symptoms and authorities
recommend 14 days of isolation for an asymptomatic individuals
who are being monitored for development of illness. To date, very
few infections among health care workers are reported, suggesting
the virus may not be as contagious as previous strains if appropriate
protective measures are taken. Despite this, stringent personal
protective precautions are recommended.
The duration of quarantine has not been determined for a patient
who has recovered from symptoms. Patients requiring hospital care
will be placed in special hospitals or isolation units of medical
facilities.
Ill or exposed individuals who are not sick enough to require
hospitalization will be subject to home isolation and monitoring in
most locations.
If contact with an infected individual is suspected, it is essential to
report immediately to a health facility and strictly adhere to
requirements for isolation from the public and other members of the
household.
Testing & diagnosis
There is a rapid R-PCR test that can definitively confirm Coronavirus
infection. The test is done by nasal swab and/or blood draw (or
bronchial secretions in hospitalized patients). Testing is only done
on patients with symptoms as a test on a patient who is in the
incubation phase with no symptoms may yield a false negative
result. At this stage, most private facilities do not have the test. It is
generally only available at public facilities or public health
laboratories. For this reason, it may take up to 48 hours to have
results.
Treatment
There is no specific treatment for the illness. There is no preventive
vaccine or medication that is effective.
Only supportive measure like supplemental oxygen, ventilators and
general health measures are indicated until the infection abates.
Preventive measures
▪ All non-essential travel to mainland China should be deferred or
cancelled. It is advisable not to travel if you have symptoms of a
viral syndrome that could be confused with Coronavirus as this
could result in detainment until this infection has been
definitively ruled out. In Asia, authorities advise avoiding live
markets and not to touch animals or eat game meat. Avoid
visiting wet markets, live poultry markets or farms and ensure all
animal products are well cooked.
▪ Patient with symptoms of cough, shortness of breath and/or
fever, especially with a history of travel to China are advised to
immediately seek medical attention. If arriving by air, you should
report this to airport authorities immediately upon deplaning.
▪ Use stringent hygiene practices:
➢ Wash hands regularly and liberally use alcohol based
disinfectant lotions.
➢ Clean surfaces regularly.
➢ Avoid proximity to others who are coughing or have a fever.
➢ If you have symptoms (coughing or sneezing), put on a
surgical mask to avoid contaminating other people and
stringently cover your face with tissue or a flexed arm when
coughing.
January 31, 2020
➢ Report any concerning symptoms to your manager at work
before reporting for duty.
➢ Consult your workplace manager regarding any additional
measures advised by your employer.
➢ If you suspect you have had contact with a person infected by
Coronavirus, report immediately to a health facility and
strictly follow local requirements for personal isolation to
avoid infecting other individuals.
▪ Make sure to get your annual flu vaccine. This will not protect
against2019-nCoV, but will reduce the likelihood of contacting
standard flu, which may be indistinguishable at onset from the
new outbreak and which may require isolation or detention until
the cause is confirmed.
▪ Health care facilities are to take isolation precautions on any
patients with the above symptoms and who have traveled from
the source of the outbreak in China.
▪ Be prepared to be screened by remote temperature sensors in
airports, especially where flights are arriving from Wuhan.

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Health alert: Outbreak of Coronavirus2019-nCov (Fact Sheet #3)

  • 1. Outbreak of Coronavirus2019-nCov Fact Sheet #3 Information from: Dr. Cai Glushak, AXA Partners Chief Medical Officer and Dr. Alan Tan, AXA Partners Asia Region Medical Director Situation The World Health Organization (WHO) has declared Public Health Emergency of International Concern (PHEIC) now that the 2019 Coronavirus has spread to multiple countries. A recent outbreak of severe respiratory infection that originated in Wuhan City in Hubei Province, China has now been traced to a newly identified virus, named 2019-nCoV. It is classified as a Coronavirus, which is in the same family of viruses that caused the SARS and Middle East Respiratory Syndrome in previous years, but it is not the same agent and has a different disease severity profile. It is also different from all influenza viruses, A, B and H1N1and other avian flu virus. Source The origin of the infection has been traced to a live animal and seafood market in Wuhan City. While originally most victims came from Wuhan City, within China secondary person-to-person transmission is now clearly established. Spread It is now established that person-to-person spread of the virus is possible, although this has been very limited outside of China. Spread is primarily by respiratory contamination, but also thought to be possible through droplets from surface contact. Hence hygiene precautions should focus on avoidance of contamination through coughing and sneezing as well as cleansing of surfaces, contaminated clothing. Clinical syndrome Symptoms of the current illness are: ➢ Fever and ➢ Shortness of breath and/or ➢ Cough – usually a dry cough ➢ Less common: o Runny nose o Sneezing o Diarrhea Since these are very non-specific symptoms, criteria for suspecting the syndrome also include recent presence in a high-risk area, primarily Wuhan City, or close contact with someone who has been in that location. If secondary spread becomes prevalent, suspicion for Coronavirus infection may include those with no such history. Complication and death Most patients do not develop severe illness. A minority have severe respiratory illness requiring intensive treatment and a small percentage (thus far 3-4%) have died. It is as yet unknown how prevalent the infection may be in patients with mild illness who have not come to clinical attention. Infectivity The incubation period for the virus and duration the patient remains contagious after illness is unknown. Based on prior Coronavirus outbreaks, health authorities advise it may take up to 12 days before an exposed person may develop symptoms and authorities recommend 14 days of isolation for an asymptomatic individuals who are being monitored for development of illness. To date, very few infections among health care workers are reported, suggesting the virus may not be as contagious as previous strains if appropriate protective measures are taken. Despite this, stringent personal protective precautions are recommended. The duration of quarantine has not been determined for a patient who has recovered from symptoms. Patients requiring hospital care will be placed in special hospitals or isolation units of medical facilities. Ill or exposed individuals who are not sick enough to require hospitalization will be subject to home isolation and monitoring in most locations. If contact with an infected individual is suspected, it is essential to report immediately to a health facility and strictly adhere to requirements for isolation from the public and other members of the household. Testing & diagnosis There is a rapid R-PCR test that can definitively confirm Coronavirus infection. The test is done by nasal swab and/or blood draw (or bronchial secretions in hospitalized patients). Testing is only done on patients with symptoms as a test on a patient who is in the incubation phase with no symptoms may yield a false negative result. At this stage, most private facilities do not have the test. It is generally only available at public facilities or public health laboratories. For this reason, it may take up to 48 hours to have results. Treatment There is no specific treatment for the illness. There is no preventive vaccine or medication that is effective. Only supportive measure like supplemental oxygen, ventilators and general health measures are indicated until the infection abates. Preventive measures ▪ All non-essential travel to mainland China should be deferred or cancelled. It is advisable not to travel if you have symptoms of a viral syndrome that could be confused with Coronavirus as this could result in detainment until this infection has been definitively ruled out. In Asia, authorities advise avoiding live markets and not to touch animals or eat game meat. Avoid visiting wet markets, live poultry markets or farms and ensure all animal products are well cooked. ▪ Patient with symptoms of cough, shortness of breath and/or fever, especially with a history of travel to China are advised to immediately seek medical attention. If arriving by air, you should report this to airport authorities immediately upon deplaning. ▪ Use stringent hygiene practices: ➢ Wash hands regularly and liberally use alcohol based disinfectant lotions. ➢ Clean surfaces regularly. ➢ Avoid proximity to others who are coughing or have a fever. ➢ If you have symptoms (coughing or sneezing), put on a surgical mask to avoid contaminating other people and stringently cover your face with tissue or a flexed arm when coughing. January 31, 2020
  • 2. ➢ Report any concerning symptoms to your manager at work before reporting for duty. ➢ Consult your workplace manager regarding any additional measures advised by your employer. ➢ If you suspect you have had contact with a person infected by Coronavirus, report immediately to a health facility and strictly follow local requirements for personal isolation to avoid infecting other individuals. ▪ Make sure to get your annual flu vaccine. This will not protect against2019-nCoV, but will reduce the likelihood of contacting standard flu, which may be indistinguishable at onset from the new outbreak and which may require isolation or detention until the cause is confirmed. ▪ Health care facilities are to take isolation precautions on any patients with the above symptoms and who have traveled from the source of the outbreak in China. ▪ Be prepared to be screened by remote temperature sensors in airports, especially where flights are arriving from Wuhan.