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Shock
1.
Shock : Pathophysiology
Causes & Management Dr.Anil Haripriya Assistant Professor Surgery NHDC & RC
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Hormonal response Hypothalamus
Hyperglycemia Lypolysis Gluconeogenesis Glycogenolysis Cortisol ACTH CRH
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Hypovolemic shock Same
+ Hypotension Mental status deterioration Same + Tachycardia Tachypnoea Oliguria Postural -hypotension Cold extremities CRT Diaphoresis Anxiety Severe(>40%) Moderate(20-40%) Mild (<20%)
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Septic shock Gram
–ve bacilli LPS+CD14 TNF IL-1 IL-6/IL-8 NO/PAF
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