5. Cutaneous involvement
• Lupus non specific lesions
• 2- Lupus specific lesions
* acute: 1) localized 2) generalized erythema & bullous
* sub-acute
* chronic
• Malar rash
• Sub acute rash (SCLE)
• DLE
6.
7.
8. Renal involvement
• A major cause of morbidity & admission
• 40-70% of SLE
• Within first 2 years
• Asymptomatic proteinuria, hematuria: 50%
• Nephritic or nephrotic syndrom: 30%
• CRF, RPGN, pulmonary renal vasculitis:< 5%