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Musculoskeletal involvement
• Arthralgia
• Arthritis
• Myositis
• AVN
Jaccoud’s arthropathy
Cutaneous involvement
• Lupus non specific lesions
• 2- Lupus specific lesions
* acute: 1) localized 2) generalized erythema & bullous
* sub-acute
* chronic
• Malar rash
• Sub acute rash (SCLE)
• DLE
Renal involvement
• A major cause of morbidity & admission
• 40-70% of SLE
• Within first 2 years
• Asymptomatic proteinuria, hematuria: 50%
• Nephritic or nephrotic syndrom: 30%
• CRF, RPGN, pulmonary renal vasculitis:< 5%
Nervous system involvement
Vascular OCCLUSIONS
pulmonary involvement
Cardiovascular involvement
Hematologic manifestation
Gastrointestinal involvement
Ocular Manifestation
Sle manifestations
Sle manifestations

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Sle manifestations