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Liver
Liver
• Largest gland in the body
• Weight: 1.4-1.8 kg in males
• 1.2-1.4 in females
• 150 gm at birth
• Function of the liver
• Secretion of bile & bile salt
• Metabolism of carbohydrate, fat and
protein
• Formation of heparin & anticoagulant
substances
• Detoxication
• Storage of glycogen and vitamins
• Activation of vita .D
Location …
•Occupies
right hypochondrium
epigastrium &
extends to left
hypochondrium
Surface anatomy of the liver
-The greater part of the
liver is situated under cover
of the right costal margin
- Diaphragm separates it
from the pleura, lungs,
pericardium, and heart.
Ant. View of the liver(External features
)
• Right lobe
• Cut edge of the
Falciform ligament
left lobe
• Diverging cut edges
of the superior part
of the coronary
ligament
• Fundus of the gall
bladder
Surfaces of the liver, their relations &
impressions
• Diaphragmatic
surface
 Superior surface
 Anterior surface
 Posterior surface
 Right Lateral surface
• Postero - inferior
surface= visceral
surface
Postero- infero surface= visceral
surface
Relations
• I.V.C
• the esophagus
• the stomach
• the duodenum
• the right colic flexure
• the right kidney
• Rt. Suprarenal gland
• the gallbladder.
• Porta hepatic( bile duct,H.a.H.V)
• Fissure for lig. Venoosum &
lesser omentum
• Tubular omentum
• Lig.teres
Lobes of the liver
• Rt. Lobe
• Lt .lobe
• Quadrate lobe
• Caudate lobe
Separation of the four lobes of the liver
• Right sagittal
fissure - groove
for IVC and GB
• left sagittal
fissure -
contains the
Lig. Venosum
and Lig. Teres
• Transverse
fissure -porta
hepatis
Rt. Lobe
-Largest lobe
- Occupies the right
hypochondrium
Left Lobe
– Varied in size
– Lies in the epigastric
and left
hypochondriac
regions
Lobes of the liver…..cont
Rt. & Lt lobe separated by
• Falciform ligament
• Ligamentum Venoosum
• Ligamentum teres
Caudate Lobe
-present in the posterior
surface from the Rt.
Lobe
Relations of caudate
lobe
- Inf.  the porta
hepatis
- The right  the fossa
for the inferior vena cava
- The left the fossa
for the lig.venosum.
Quadrate lobe
Present on the inferior
surface from the Rt. Lobe
Relation
- Sup. porta hepatis
- Rt. fossa for the
gallbladder
- Lt by the fossa for
lig.teres
Porta hepatis
-It is the hilum of the liver
-It is found on the
posteroinferior surface
- lies between the caudate
and quadrate lobes
-Lesser omentum attach to
its margin
Contents
Hepatic artery
Portal vein
Rt &ly hepatic duct leaving
the porta hepatis
Peritoneum of the liver
• The liver is covered by
peritoneum
(intraperitoneal
organ)except at bare
area(it is origin from
septum transversum)
• Inferior surface covered
with peritoneum of
greater sac except porta
hepatis, G.B & Lig.teres
fissure
• Rt. Lateral surface
covered by peritoneum,
related to diaphragm
which separate it from
Rt. Pleura , lung and the
Rt Ribs (6-11)
Postero- infero surface= visceral
surface
Relations
• I.V.C
• the esophagus
• the stomach
• the duodenum
• the right colic flexure
• the right kidney
• Rt. Suprarenal gland
• the gallbladder.
• Porta hepatic( bile duct,H.a.H.V)
• Fissure for lig. Venoosum &
lesser omentum
• Tubular omentum
• Lig.teres
Sup. Surface of the liver
• Right & left lobes
• Cut edge of the
Falciform ligament
• The cut edges of
the superior and
inferior parts of
the coronary
ligament
• The left triangular
ligament
• The right
triangular
ligament
Relations of Sup . surface of liver
• Diaphragm
• Pleura & lung
• Pericardium &
heart
Relations of the liver Anteriorly
• Diaphragm
• Rt & Lt pleura and
lung
• Costal cartilage
• Xiphoid process
• Ant. abdominal wall
1- The Falciform ligament of liver
2- The Ligamentum teres hepatis
3- The coronary ligament
4- The right triangular ligament
5- The left triangular ligament
6- The Hepatogastric ligament
7- The hepatoduonedenal ligament
8- The Ligamentum Venoosum
1. The ligaments of the liver
Falciform Ligament
A sickle-shaped fold of
peritoneum connects the AAW
with the liver slightly to the right
of the median plane.
• Ant border: Attached to under
surface of diaphragm & AAW
• Post border: Attached to sup &
ant surfaces of liver
• Free margin connects the
umbilicus to liver it contains the
round ligament of the liver or
Ligamentum teres.
• Coronary ligament
the area between upper and
lower layer of the coronary
ligament is the bare area of
liver which contract with the
diaphragm;
• Left and right triangular
ligaments formed by left and
right extremity of coronary
ligament
• Hepatogastric ligament
• Hepatoduodenal
ligament
The Ligamentum
Venosum
-Fibrous band that is the remains of the ductus
venosus
Segmental anatomy of the liver
• Anatomical Lobes
Rt .& Lt. lobes -no
morphological
significance.
Separation by ligaments
(Falciform, lig. Venoosum
& Lig.teres)
• True morphological and
physiological Lobes -line
extends from fossa of GB
to fossa of I.V.C each has
its own arterial blood
supply, venous drainage
and biliary drainage
Couinaud’s segments
• Structural unit of liver
• Right =Anterior & post
• Left=medial & lateral
• Each of these=Upper & lower
Couinaud’s segments
Blood supply of the liver
• Two sources
• Hepatic artery-which deliver oxygenated blood
from general circulation
• Portal vein- delivering deoxygenated blood from
small intestine
Vein drainage of the liver
• The portal vein divides
into right and left
terminal branches that
enter the porta hepatis
behind the arteries.
• The hepatic veins (three
or more) emerge from
the posterior surface of
the liver and drain into
the inferior vena cava.
Lymphatic drainage of the liver
• Superficial lymphatics-
• from post. Aspect of liver drain in to the post.
Mediastinal lymph node
• From ant. Aspect- drain in to hepatic node
• Deep lymphatics
• Terminate in the nodes around IVC
• Nerve supply
• Sympathetic  celiac plexuses
• Parasympathetic  vagus nerve( anterior part)
• The anterior vagal trunk gives rise to a large hepatic
branch, which passes directly to the liver
Liver cirrhosis- hepatocytes sometimes may undergo necrosis
The dead hepatocytes are replaced by fibrous tissue so hepatic fibrosis
clinically termed as LC
Fact
• The liver is the only
internal human organ
capable of natural
regeneration of lost
tissue; as little as 25% of a
liver can regenerate into a
whole liver.

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LIVER sonika.pptx

  • 2. Liver • Largest gland in the body • Weight: 1.4-1.8 kg in males • 1.2-1.4 in females • 150 gm at birth • Function of the liver • Secretion of bile & bile salt • Metabolism of carbohydrate, fat and protein • Formation of heparin & anticoagulant substances • Detoxication • Storage of glycogen and vitamins • Activation of vita .D
  • 4. Surface anatomy of the liver -The greater part of the liver is situated under cover of the right costal margin - Diaphragm separates it from the pleura, lungs, pericardium, and heart.
  • 5.
  • 6. Ant. View of the liver(External features ) • Right lobe • Cut edge of the Falciform ligament left lobe • Diverging cut edges of the superior part of the coronary ligament • Fundus of the gall bladder
  • 7. Surfaces of the liver, their relations & impressions • Diaphragmatic surface  Superior surface  Anterior surface  Posterior surface  Right Lateral surface • Postero - inferior surface= visceral surface
  • 8. Postero- infero surface= visceral surface Relations • I.V.C • the esophagus • the stomach • the duodenum • the right colic flexure • the right kidney • Rt. Suprarenal gland • the gallbladder. • Porta hepatic( bile duct,H.a.H.V) • Fissure for lig. Venoosum & lesser omentum • Tubular omentum • Lig.teres
  • 9.
  • 10. Lobes of the liver • Rt. Lobe • Lt .lobe • Quadrate lobe • Caudate lobe
  • 11. Separation of the four lobes of the liver • Right sagittal fissure - groove for IVC and GB • left sagittal fissure - contains the Lig. Venosum and Lig. Teres • Transverse fissure -porta hepatis
  • 12. Rt. Lobe -Largest lobe - Occupies the right hypochondrium
  • 13. Left Lobe – Varied in size – Lies in the epigastric and left hypochondriac regions
  • 14. Lobes of the liver…..cont Rt. & Lt lobe separated by • Falciform ligament • Ligamentum Venoosum • Ligamentum teres
  • 15. Caudate Lobe -present in the posterior surface from the Rt. Lobe Relations of caudate lobe - Inf.  the porta hepatis - The right  the fossa for the inferior vena cava - The left the fossa for the lig.venosum.
  • 16. Quadrate lobe Present on the inferior surface from the Rt. Lobe Relation - Sup. porta hepatis - Rt. fossa for the gallbladder - Lt by the fossa for lig.teres
  • 17. Porta hepatis -It is the hilum of the liver -It is found on the posteroinferior surface - lies between the caudate and quadrate lobes -Lesser omentum attach to its margin Contents Hepatic artery Portal vein Rt &ly hepatic duct leaving the porta hepatis
  • 18. Peritoneum of the liver • The liver is covered by peritoneum (intraperitoneal organ)except at bare area(it is origin from septum transversum) • Inferior surface covered with peritoneum of greater sac except porta hepatis, G.B & Lig.teres fissure • Rt. Lateral surface covered by peritoneum, related to diaphragm which separate it from Rt. Pleura , lung and the Rt Ribs (6-11)
  • 19. Postero- infero surface= visceral surface Relations • I.V.C • the esophagus • the stomach • the duodenum • the right colic flexure • the right kidney • Rt. Suprarenal gland • the gallbladder. • Porta hepatic( bile duct,H.a.H.V) • Fissure for lig. Venoosum & lesser omentum • Tubular omentum • Lig.teres
  • 20.
  • 21. Sup. Surface of the liver • Right & left lobes • Cut edge of the Falciform ligament • The cut edges of the superior and inferior parts of the coronary ligament • The left triangular ligament • The right triangular ligament
  • 22. Relations of Sup . surface of liver • Diaphragm • Pleura & lung • Pericardium & heart
  • 23. Relations of the liver Anteriorly • Diaphragm • Rt & Lt pleura and lung • Costal cartilage • Xiphoid process • Ant. abdominal wall
  • 24.
  • 25. 1- The Falciform ligament of liver 2- The Ligamentum teres hepatis 3- The coronary ligament 4- The right triangular ligament 5- The left triangular ligament 6- The Hepatogastric ligament 7- The hepatoduonedenal ligament 8- The Ligamentum Venoosum 1. The ligaments of the liver
  • 26. Falciform Ligament A sickle-shaped fold of peritoneum connects the AAW with the liver slightly to the right of the median plane. • Ant border: Attached to under surface of diaphragm & AAW • Post border: Attached to sup & ant surfaces of liver • Free margin connects the umbilicus to liver it contains the round ligament of the liver or Ligamentum teres.
  • 27. • Coronary ligament the area between upper and lower layer of the coronary ligament is the bare area of liver which contract with the diaphragm; • Left and right triangular ligaments formed by left and right extremity of coronary ligament
  • 28. • Hepatogastric ligament • Hepatoduodenal ligament
  • 29. The Ligamentum Venosum -Fibrous band that is the remains of the ductus venosus
  • 30. Segmental anatomy of the liver • Anatomical Lobes Rt .& Lt. lobes -no morphological significance. Separation by ligaments (Falciform, lig. Venoosum & Lig.teres) • True morphological and physiological Lobes -line extends from fossa of GB to fossa of I.V.C each has its own arterial blood supply, venous drainage and biliary drainage
  • 31. Couinaud’s segments • Structural unit of liver • Right =Anterior & post • Left=medial & lateral • Each of these=Upper & lower
  • 33. Blood supply of the liver • Two sources • Hepatic artery-which deliver oxygenated blood from general circulation • Portal vein- delivering deoxygenated blood from small intestine
  • 34. Vein drainage of the liver • The portal vein divides into right and left terminal branches that enter the porta hepatis behind the arteries. • The hepatic veins (three or more) emerge from the posterior surface of the liver and drain into the inferior vena cava.
  • 35. Lymphatic drainage of the liver • Superficial lymphatics- • from post. Aspect of liver drain in to the post. Mediastinal lymph node • From ant. Aspect- drain in to hepatic node • Deep lymphatics • Terminate in the nodes around IVC
  • 36. • Nerve supply • Sympathetic  celiac plexuses • Parasympathetic  vagus nerve( anterior part) • The anterior vagal trunk gives rise to a large hepatic branch, which passes directly to the liver
  • 37. Liver cirrhosis- hepatocytes sometimes may undergo necrosis The dead hepatocytes are replaced by fibrous tissue so hepatic fibrosis clinically termed as LC
  • 38. Fact • The liver is the only internal human organ capable of natural regeneration of lost tissue; as little as 25% of a liver can regenerate into a whole liver.