This study examined how demographic factors and symptoms are associated with asthma self-management among 652 women with physician-diagnosed asthma. It found that minority women, those with lower income/education, and unemployed women were more likely to have persistent asthma and use management techniques more frequently. Women who experienced premenstrual symptoms or asthma symptoms during sex had significantly more healthcare utilization. Adopting management techniques was associated with more severe asthma, though disease severity was unrelated to beliefs or confidence in management.