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Factors Associated with Persistent Disease in Women with Asthma Noreen Clark, PhD  Molly Gong, MD Jimmy Yu, PhD Candidate ...
Background <ul><li>Five million women are currently diagnosed with asthma (Crespo 1997)  </li></ul><ul><li>Morbidity rates...
Purpose <ul><li>To examine demographic, psychosocial, and lifestyle factors associated with persistent asthma in women. </...
Data collection <ul><li>Participants </li></ul><ul><ul><li>439 women </li></ul></ul><ul><ul><li>18 years and older </li></...
Data collection <ul><li>Data: telephone interview </li></ul><ul><ul><li>asthma symptoms </li></ul></ul><ul><ul><li>gender ...
Data Analyses <ul><li>A dichotomous dependent variable (1=persistent asthma including mild, moderate, and severe; 0=otherw...
Sample demographics Age
Sample demographics Education Level
Sample demographics <ul><li>Annual Household Income </li></ul>
Sample demographics <ul><li>Race/Ethnicity </li></ul>
Asthma severity  <ul><li>Classified by NAEPP criteria, USA, Guidelines and Diagnosis and Treatment of Asthma </li></ul>Cla...
Findings Significant demographics factors associated with persistent asthma Educational level was significantly associated...
Findings Significant demographic factors associated with persistent asthma Annual household income was significantly relat...
Findings Significant demographics factors associated with persistent asthma Not working for pay was significantly associat...
Findings Significant physical factors associated with persistent asthma The higher the BMI, the higher the probability of ...
Findings Significant lifestyle factors associated with persistent asthma The less the exercise, the higher the probability...
Findings Significant psycho social factors associated with persistent asthma The lower the level of self-esteem, the highe...
Findings Significant psycho social factors associated with persistent asthma The more the social support, the higher the p...
Findings Significant psycho social factors associated with persistent asthma The higher the self-regulation level, the hig...
Study Limitations <ul><li>This study sample includes a number of women with high levels of education and income. </li></ul...
Conclusions <ul><li>1.  Low annual household income, a lower level of education, and not working for pay were associated w...
Conclusions (con’t) <ul><li>2.  Women with persistent asthma were more likely to have high BMI, maintain a low level of ex...
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Factors associated with persistent disease in women with asthma

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Factors associated with persistent disease in women with asthma

Noreen Clark
Center for Managing Chronic Disease
University of Michigan

Published in: Health & Medicine
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Factors associated with persistent disease in women with asthma

  1. 1. Factors Associated with Persistent Disease in Women with Asthma Noreen Clark, PhD Molly Gong, MD Jimmy Yu, PhD Candidate Xihong Lin, PhD Melissa Valerio, MPH William Bria, MD Timothy Johnson, MD University of Michigan School of Public Health Supported by NHLBI Grant # HL60884
  2. 2. Background <ul><li>Five million women are currently diagnosed with asthma (Crespo 1997) </li></ul><ul><li>Morbidity rates are disproportionately higher for women compared to men (CDC 1995). </li></ul><ul><li>Women also have consistently higher rates of asthma clinic visits, hospital admissions and re-admissions (CDC 1995 ). </li></ul>
  3. 3. Purpose <ul><li>To examine demographic, psychosocial, and lifestyle factors associated with persistent asthma in women. </li></ul>
  4. 4. Data collection <ul><li>Participants </li></ul><ul><ul><li>439 women </li></ul></ul><ul><ul><li>18 years and older </li></ul></ul><ul><ul><li>physician diagnosis </li></ul></ul><ul><ul><li>University of Michigan Asthma & Airways Clinic and University of Michigan Health System </li></ul></ul>
  5. 5. Data collection <ul><li>Data: telephone interview </li></ul><ul><ul><li>asthma symptoms </li></ul></ul><ul><ul><li>gender related management </li></ul></ul><ul><ul><li>psychosocial factors and lifestyle </li></ul></ul>
  6. 6. Data Analyses <ul><li>A dichotomous dependent variable (1=persistent asthma including mild, moderate, and severe; 0=otherwise) was created to explore the factors associated with persistent asthma. </li></ul><ul><li>Univariate and multivariate logistic regression models were conducted. </li></ul><ul><li>Odds Ratio and p-value were computed. </li></ul>
  7. 7. Sample demographics Age
  8. 8. Sample demographics Education Level
  9. 9. Sample demographics <ul><li>Annual Household Income </li></ul>
  10. 10. Sample demographics <ul><li>Race/Ethnicity </li></ul>
  11. 11. Asthma severity <ul><li>Classified by NAEPP criteria, USA, Guidelines and Diagnosis and Treatment of Asthma </li></ul>Classified by NAEPP criteria, Guidelines and Diagnosis and Treatment of Asthma, NHLBI, NIH, 1997 14.58 Severe persistent 18.45 Moderate persistent 14.35 Mild persistent 52.62 Mild intermittent Percent of Women
  12. 12. Findings Significant demographics factors associated with persistent asthma Educational level was significantly associated with persistent disease. The lower the education level, the higher the probability of persistent asthma. .03 1.20 .084 -.1856 438 Education P-value OR SE Estimate N Factor (1)
  13. 13. Findings Significant demographic factors associated with persistent asthma Annual household income was significantly related to persistent disease. The lower the income, the higher the probability of persistent asthma. .02 1.13 .063 -.1474 386 Annual Household Income P-value OR SE Estimate N Factor (2)
  14. 14. Findings Significant demographics factors associated with persistent asthma Not working for pay was significantly associated with persistent asthma. .02 1.59 .198 -.47 438 Working for pay P-value OR SE Estimate N Factor (3)
  15. 15. Findings Significant physical factors associated with persistent asthma The higher the BMI, the higher the probability of persistent asthma. .02 1.03 .0124 .0302 430 BMI (mean=29.5, SD=7.97) P-value OR SE Estimate N Factor
  16. 16. Findings Significant lifestyle factors associated with persistent asthma The less the exercise, the higher the probability of persistent asthma. .006 1.16 .0547 -.149 436 Frequency of exercise (mean=3.46, SD=1.79) P-value OR SE Estimate N Factor
  17. 17. Findings Significant psycho social factors associated with persistent asthma The lower the level of self-esteem, the higher the probability of persistent asthma. .0176 1.04 .0191 -.0454 438 Self-esteem score (mean=24.66, SD=2.33) P-value OR SE Estimate N Factor (1)
  18. 18. Findings Significant psycho social factors associated with persistent asthma The more the social support, the higher the probability of persistent asthma. .034 1.04 .0181 .0385 438 Overall social support score (mean=12.61, SD=5.20) P-value OR SE Estimate N Factor (2)
  19. 19. Findings Significant psycho social factors associated with persistent asthma The higher the self-regulation level, the higher the probability of persistent asthma. .0001 1.66 .214 .5056 439 Self-regulation phases (mean=2.17, SD=1.20) P-value OR SE Estimate N Factor (3)
  20. 20. Study Limitations <ul><li>This study sample includes a number of women with high levels of education and income. </li></ul><ul><li>The findings reported here are from preliminary analysis. </li></ul>
  21. 21. Conclusions <ul><li>1. Low annual household income, a lower level of education, and not working for pay were associated with persistent asthma, whereas, age, marital status, and ethnicity were not. </li></ul>
  22. 22. Conclusions (con’t) <ul><li>2. Women with persistent asthma were more likely to have high BMI, maintain a low level of exercise, have lower self-esteem, had more social support, and be at a higher level of self-regulation related to asthma compared to women with intermittent disease. </li></ul>

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