SlideShare a Scribd company logo
1 of 22
Proteomics  For any given species, the space of possible biomolecules and their organization into pathways and processes is large but finite.  BY SRITANU DAS MAHAPATRA ASIA-PACIFIC INSTITUTE OF MANAGEMENT STUDIES
[object Object]
Proteomics ,[object Object],[object Object]
 
How to organize information? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Transposon tagging to identify ORFS Why include a URA3 gene? Why have a lacZ lacking a promoter? Why would you want to cut out all the intervening DNA?
High throughput tests of function
Yeast deletion strains
Microscopic localization
microscopy
Process for protein isolation
2D gel electrophoresis
Antibody arrays Good for low-abundance proteins Problem is antibody specificity
Array-based protein interaction detection
Protein microarrays
Caveats ,[object Object],[object Object],[object Object]
MS analysis
MS analysis
Two-hybrid analysis
Interaction maps - Grid
Goals- Aebersold ,[object Object],[object Object],[object Object]
challenges ,[object Object],[object Object],[object Object],[object Object]

More Related Content

What's hot

Functional proteomics, and tools
Functional proteomics, and toolsFunctional proteomics, and tools
Functional proteomics, and toolsKAUSHAL SAHU
 
Structural genomics
Structural genomicsStructural genomics
Structural genomicsAshfaq Ahmad
 
Techniques in proteomics
Techniques in proteomicsTechniques in proteomics
Techniques in proteomicsN Poorin
 
Transcriptomics and metabolomics
Transcriptomics and metabolomicsTranscriptomics and metabolomics
Transcriptomics and metabolomicsSukhjinder Singh
 
STRING - Prediction of a functional association network for the yeast mitocho...
STRING - Prediction of a functional association network for the yeast mitocho...STRING - Prediction of a functional association network for the yeast mitocho...
STRING - Prediction of a functional association network for the yeast mitocho...Lars Juhl Jensen
 
Magnetic Resonance Spectroscopy and Metabolomics
Magnetic Resonance Spectroscopy and MetabolomicsMagnetic Resonance Spectroscopy and Metabolomics
Magnetic Resonance Spectroscopy and MetabolomicsUzay Emir
 
Protein Microarrays
Protein MicroarraysProtein Microarrays
Protein MicroarraysRomilMistry
 
Bioinformatics of cellular processes
Bioinformatics of cellular processesBioinformatics of cellular processes
Bioinformatics of cellular processesLars Juhl Jensen
 
Genomics and proteomics ppt
Genomics and proteomics pptGenomics and proteomics ppt
Genomics and proteomics pptPatelSupriya
 
Structural genomics
Structural genomicsStructural genomics
Structural genomicsAshfaq Ahmad
 
Cloud applications - Protein Structure Predication and gene expression data...
Cloud applications - Protein Structure Predication  and  gene expression data...Cloud applications - Protein Structure Predication  and  gene expression data...
Cloud applications - Protein Structure Predication and gene expression data...Pushpendra Singh Dangi
 
From Ugly Duckling to Swan: Unexpected Identification from Cell-SELEX
From Ugly Duckling to Swan: Unexpected Identification from Cell-SELEXFrom Ugly Duckling to Swan: Unexpected Identification from Cell-SELEX
From Ugly Duckling to Swan: Unexpected Identification from Cell-SELEXSaw Yi
 
Microbial Genomics and Bioinformatics: BM405 (2015)
Microbial Genomics and Bioinformatics: BM405 (2015)Microbial Genomics and Bioinformatics: BM405 (2015)
Microbial Genomics and Bioinformatics: BM405 (2015)Leighton Pritchard
 
Systems biology & Approaches of genomics and proteomics
 Systems biology & Approaches of genomics and proteomics Systems biology & Approaches of genomics and proteomics
Systems biology & Approaches of genomics and proteomicssonam786
 

What's hot (20)

Functional proteomics, and tools
Functional proteomics, and toolsFunctional proteomics, and tools
Functional proteomics, and tools
 
Structural genomics
Structural genomicsStructural genomics
Structural genomics
 
Techniques in proteomics
Techniques in proteomicsTechniques in proteomics
Techniques in proteomics
 
Transcriptomics and metabolomics
Transcriptomics and metabolomicsTranscriptomics and metabolomics
Transcriptomics and metabolomics
 
STRING - Prediction of a functional association network for the yeast mitocho...
STRING - Prediction of a functional association network for the yeast mitocho...STRING - Prediction of a functional association network for the yeast mitocho...
STRING - Prediction of a functional association network for the yeast mitocho...
 
Magnetic Resonance Spectroscopy and Metabolomics
Magnetic Resonance Spectroscopy and MetabolomicsMagnetic Resonance Spectroscopy and Metabolomics
Magnetic Resonance Spectroscopy and Metabolomics
 
Genomics
Genomics Genomics
Genomics
 
Protein Microarrays
Protein MicroarraysProtein Microarrays
Protein Microarrays
 
Bioinformatics of cellular processes
Bioinformatics of cellular processesBioinformatics of cellular processes
Bioinformatics of cellular processes
 
Arraygen bioinformatics ppt
Arraygen bioinformatics pptArraygen bioinformatics ppt
Arraygen bioinformatics ppt
 
Genomics and proteomics ppt
Genomics and proteomics pptGenomics and proteomics ppt
Genomics and proteomics ppt
 
Genomics types
Genomics typesGenomics types
Genomics types
 
Systems biology
Systems biologySystems biology
Systems biology
 
Structural genomics
Structural genomicsStructural genomics
Structural genomics
 
Cloud applications - Protein Structure Predication and gene expression data...
Cloud applications - Protein Structure Predication  and  gene expression data...Cloud applications - Protein Structure Predication  and  gene expression data...
Cloud applications - Protein Structure Predication and gene expression data...
 
From Ugly Duckling to Swan: Unexpected Identification from Cell-SELEX
From Ugly Duckling to Swan: Unexpected Identification from Cell-SELEXFrom Ugly Duckling to Swan: Unexpected Identification from Cell-SELEX
From Ugly Duckling to Swan: Unexpected Identification from Cell-SELEX
 
Microbial Genomics and Bioinformatics: BM405 (2015)
Microbial Genomics and Bioinformatics: BM405 (2015)Microbial Genomics and Bioinformatics: BM405 (2015)
Microbial Genomics and Bioinformatics: BM405 (2015)
 
genomic comparison
genomic comparison genomic comparison
genomic comparison
 
Systems biology & Approaches of genomics and proteomics
 Systems biology & Approaches of genomics and proteomics Systems biology & Approaches of genomics and proteomics
Systems biology & Approaches of genomics and proteomics
 
15 arrays
15 arrays15 arrays
15 arrays
 

Viewers also liked

Yeast 2 hybrid system ppt by meera qaiser
Yeast 2 hybrid system ppt by meera qaiserYeast 2 hybrid system ppt by meera qaiser
Yeast 2 hybrid system ppt by meera qaiserQaiser Sethi
 
Yeast two hybrid system / protein-protein interaction
Yeast two hybrid system / protein-protein interactionYeast two hybrid system / protein-protein interaction
Yeast two hybrid system / protein-protein interactionMaryam Shakeel
 
Protein-Protein Interactions (PPIs)
Protein-Protein Interactions (PPIs)Protein-Protein Interactions (PPIs)
Protein-Protein Interactions (PPIs)Sai Ram
 
Yeast two hybrid
Yeast two hybridYeast two hybrid
Yeast two hybridhina ojha
 
Protein-protein interaction (PPI)
Protein-protein interaction (PPI)Protein-protein interaction (PPI)
Protein-protein interaction (PPI)N Poorin
 
Protein protein interactions
Protein protein interactionsProtein protein interactions
Protein protein interactionsPrianca12
 

Viewers also liked (8)

Yeast two hybrid method
Yeast two hybrid methodYeast two hybrid method
Yeast two hybrid method
 
Yeast 2 hybrid system ppt by meera qaiser
Yeast 2 hybrid system ppt by meera qaiserYeast 2 hybrid system ppt by meera qaiser
Yeast 2 hybrid system ppt by meera qaiser
 
Yeast n hybrid
Yeast n hybridYeast n hybrid
Yeast n hybrid
 
Yeast two hybrid system / protein-protein interaction
Yeast two hybrid system / protein-protein interactionYeast two hybrid system / protein-protein interaction
Yeast two hybrid system / protein-protein interaction
 
Protein-Protein Interactions (PPIs)
Protein-Protein Interactions (PPIs)Protein-Protein Interactions (PPIs)
Protein-Protein Interactions (PPIs)
 
Yeast two hybrid
Yeast two hybridYeast two hybrid
Yeast two hybrid
 
Protein-protein interaction (PPI)
Protein-protein interaction (PPI)Protein-protein interaction (PPI)
Protein-protein interaction (PPI)
 
Protein protein interactions
Protein protein interactionsProtein protein interactions
Protein protein interactions
 

Similar to Proteomics

bioinformatics simple
bioinformatics simple bioinformatics simple
bioinformatics simple nadeem akhter
 
Proteomics, definatio , general concept, signficance
Proteomics,  definatio , general concept, signficanceProteomics,  definatio , general concept, signficance
Proteomics, definatio , general concept, signficanceKAUSHAL SAHU
 
Yeast two hybrid system
Yeast two hybrid systemYeast two hybrid system
Yeast two hybrid systemiqraakbar8
 
protein microarray.pptx
protein microarray.pptxprotein microarray.pptx
protein microarray.pptxAtulSingh77625
 
Proteomics and its applications in phytopathology
Proteomics and its applications in phytopathologyProteomics and its applications in phytopathology
Proteomics and its applications in phytopathologyAbhijeet Kashyap
 
Proteomics in VSC for crop improvement programme
Proteomics in VSC for crop improvement programmeProteomics in VSC for crop improvement programme
Proteomics in VSC for crop improvement programmeSumanthBT1
 
00002 Jc Silva 2006 Mcp V5n1p144
00002 Jc Silva 2006 Mcp V5n1p14400002 Jc Silva 2006 Mcp V5n1p144
00002 Jc Silva 2006 Mcp V5n1p144jcruzsilva
 
Genomics and proteomics in drug discovery and development
Genomics and proteomics in drug discovery and developmentGenomics and proteomics in drug discovery and development
Genomics and proteomics in drug discovery and developmentSuchittaU
 
Targeted and Discovery Proteomics
Targeted and Discovery ProteomicsTargeted and Discovery Proteomics
Targeted and Discovery ProteomicsCreative Proteomics
 
Bioinformatics, application by kk sahu sir
Bioinformatics, application by kk sahu sirBioinformatics, application by kk sahu sir
Bioinformatics, application by kk sahu sirKAUSHAL SAHU
 
Protein Qualitative Analysis Services
Protein Qualitative Analysis ServicesProtein Qualitative Analysis Services
Protein Qualitative Analysis ServicesCreative Proteomics
 
00003 Jc Silva 2006 Mcp V5n4p589
00003 Jc Silva 2006 Mcp V5n4p58900003 Jc Silva 2006 Mcp V5n4p589
00003 Jc Silva 2006 Mcp V5n4p589jcruzsilva
 
Systems Biology Approaches to Cancer
Systems Biology Approaches to CancerSystems Biology Approaches to Cancer
Systems Biology Approaches to CancerRaunak Shrestha
 
Making Protein Function and Subcellular Localization Predictions: Challenges ...
Making Protein Function and Subcellular Localization Predictions: Challenges ...Making Protein Function and Subcellular Localization Predictions: Challenges ...
Making Protein Function and Subcellular Localization Predictions: Challenges ...fionabrinkman
 

Similar to Proteomics (20)

bioinformatics simple
bioinformatics simple bioinformatics simple
bioinformatics simple
 
Proteomics, definatio , general concept, signficance
Proteomics,  definatio , general concept, signficanceProteomics,  definatio , general concept, signficance
Proteomics, definatio , general concept, signficance
 
Yeast two hybrid system
Yeast two hybrid systemYeast two hybrid system
Yeast two hybrid system
 
protein microarray.pptx
protein microarray.pptxprotein microarray.pptx
protein microarray.pptx
 
Proteomic and metabolomic
Proteomic and metabolomicProteomic and metabolomic
Proteomic and metabolomic
 
Proteomics and its applications in phytopathology
Proteomics and its applications in phytopathologyProteomics and its applications in phytopathology
Proteomics and its applications in phytopathology
 
Proteomics
ProteomicsProteomics
Proteomics
 
proteomics
 proteomics proteomics
proteomics
 
Proteomics in VSC for crop improvement programme
Proteomics in VSC for crop improvement programmeProteomics in VSC for crop improvement programme
Proteomics in VSC for crop improvement programme
 
00002 Jc Silva 2006 Mcp V5n1p144
00002 Jc Silva 2006 Mcp V5n1p14400002 Jc Silva 2006 Mcp V5n1p144
00002 Jc Silva 2006 Mcp V5n1p144
 
Genomics and proteomics in drug discovery and development
Genomics and proteomics in drug discovery and developmentGenomics and proteomics in drug discovery and development
Genomics and proteomics in drug discovery and development
 
Targeted and Discovery Proteomics
Targeted and Discovery ProteomicsTargeted and Discovery Proteomics
Targeted and Discovery Proteomics
 
Bioinformatics, application by kk sahu sir
Bioinformatics, application by kk sahu sirBioinformatics, application by kk sahu sir
Bioinformatics, application by kk sahu sir
 
Proteomics
Proteomics   Proteomics
Proteomics
 
Genomics & Proteomics Based Drug Discovery
Genomics & Proteomics Based Drug DiscoveryGenomics & Proteomics Based Drug Discovery
Genomics & Proteomics Based Drug Discovery
 
Proteomics.pptx
Proteomics.pptxProteomics.pptx
Proteomics.pptx
 
Protein Qualitative Analysis Services
Protein Qualitative Analysis ServicesProtein Qualitative Analysis Services
Protein Qualitative Analysis Services
 
00003 Jc Silva 2006 Mcp V5n4p589
00003 Jc Silva 2006 Mcp V5n4p58900003 Jc Silva 2006 Mcp V5n4p589
00003 Jc Silva 2006 Mcp V5n4p589
 
Systems Biology Approaches to Cancer
Systems Biology Approaches to CancerSystems Biology Approaches to Cancer
Systems Biology Approaches to Cancer
 
Making Protein Function and Subcellular Localization Predictions: Challenges ...
Making Protein Function and Subcellular Localization Predictions: Challenges ...Making Protein Function and Subcellular Localization Predictions: Challenges ...
Making Protein Function and Subcellular Localization Predictions: Challenges ...
 

Proteomics