SlideShare a Scribd company logo
1 of 25
Substrate-Independent
        Minds
     Randal A. Koene
     Carboncopies.org




                        1
DYSTOPIA




           2
SELECTION




            3
EMPATHY




          4
CHALLENGES




             5
AUGMENTED




            6
BEING




        7
SUBSTRATE-
INDEPENDENT
MINDS




                 WHOLE
                  BRAIN
              EMULATION8
SYSTEM IDENTIFICATION
ROADMAP
REQUIREMENTS




               11
SCOPE
RESOLUTION




             12
EMULATION
PLATFORM    80 million ATP per action
            potential
            Brain: 20-40W (20-44% of
            body)
            Average action potential
            takes 1.5ms
            About 4nW per event
            Supports 7 billion
            concurrent events
            Average rate 4-7Hz... 470
            billion events/s
                                   13
STRUCTURAL
CONNECTOME




             14
15
16
FUNCTIONAL
CHARACTERIZATION




                   17
MOLECULAR
TICKER TAPE




      Kording (Northwestern), Boyden (MIT), Church (Harvard), Koene   18
FUNCTIONALIZED
NANOPARTICLES
WIRELESS
MICROPROBES




              Gomez-Martinez et al. (2009)
                                       20
21
TEAM
NETWORK

          2um   1um




                      22
Carboncopies.org
B



BODY




           BRAIN
Thank You
    carboncopies.org
randal.a.koene@carboncopies.org



                                  25

More Related Content

Similar to Dr. Randal Koene: Substrate-Independent Minds (Australian Singularity Summit 2012)

Ethical issues involved in hybrid bionic systems
Ethical issues involved in hybrid bionic systemsEthical issues involved in hybrid bionic systems
Ethical issues involved in hybrid bionic systems
Karlos Svoboda
 
SF Big Analytics20170706: What the brain tells us about the future of streami...
SF Big Analytics20170706: What the brain tells us about the future of streami...SF Big Analytics20170706: What the brain tells us about the future of streami...
SF Big Analytics20170706: What the brain tells us about the future of streami...
Chester Chen
 

Similar to Dr. Randal Koene: Substrate-Independent Minds (Australian Singularity Summit 2012) (20)

How Point of Care Diagnostics Will Change the Future of Health Care, Dr. Andr...
How Point of Care Diagnostics Will Change the Future of Health Care, Dr. Andr...How Point of Care Diagnostics Will Change the Future of Health Care, Dr. Andr...
How Point of Care Diagnostics Will Change the Future of Health Care, Dr. Andr...
 
Human encodeproject
Human encodeprojectHuman encodeproject
Human encodeproject
 
Вычислительный эксперимент в молекулярной биофизике белков и биомембран
Вычислительный эксперимент в молекулярной биофизике белков и биомембранВычислительный эксперимент в молекулярной биофизике белков и биомембран
Вычислительный эксперимент в молекулярной биофизике белков и биомембран
 
Specificity Assessment At Santaris Pharma
Specificity Assessment At Santaris PharmaSpecificity Assessment At Santaris Pharma
Specificity Assessment At Santaris Pharma
 
Dna computing
Dna computingDna computing
Dna computing
 
Rob Meagley and Andrew Bleloch at Health Extension Salon #5
Rob Meagley and Andrew Bleloch at Health Extension Salon #5Rob Meagley and Andrew Bleloch at Health Extension Salon #5
Rob Meagley and Andrew Bleloch at Health Extension Salon #5
 
Handling molecular machines by our hands: beyond Nobel Prize and Nanotechnology.
Handling molecular machines by our hands: beyond Nobel Prize and Nanotechnology.Handling molecular machines by our hands: beyond Nobel Prize and Nanotechnology.
Handling molecular machines by our hands: beyond Nobel Prize and Nanotechnology.
 
Introduction to systems biology – How systems work?
Introduction to systems biology – How systems work?Introduction to systems biology – How systems work?
Introduction to systems biology – How systems work?
 
Final project report
Final project reportFinal project report
Final project report
 
P
 Systems 
Model 
Optimisation 
by
 Means 
of 
Evolutionary 
Based 
Search
 ...
P
 Systems 
Model 
Optimisation 
by
 Means 
of 
Evolutionary 
Based 
Search
 ...P
 Systems 
Model 
Optimisation 
by
 Means 
of 
Evolutionary 
Based 
Search
 ...
P
 Systems 
Model 
Optimisation 
by
 Means 
of 
Evolutionary 
Based 
Search
 ...
 
Bruce Damer's talk at EE380, the Stanford University Computer Systems Colloqu...
Bruce Damer's talk at EE380, the Stanford University Computer Systems Colloqu...Bruce Damer's talk at EE380, the Stanford University Computer Systems Colloqu...
Bruce Damer's talk at EE380, the Stanford University Computer Systems Colloqu...
 
Functional genomics
Functional genomicsFunctional genomics
Functional genomics
 
15 arrays
15 arrays15 arrays
15 arrays
 
Ethical issues involved in hybrid bionic systems
Ethical issues involved in hybrid bionic systemsEthical issues involved in hybrid bionic systems
Ethical issues involved in hybrid bionic systems
 
DNA Barcoding
DNA BarcodingDNA Barcoding
DNA Barcoding
 
Dipesh
DipeshDipesh
Dipesh
 
On a quiz that Im using to prepare for my test I made a 1.32 poin.pdf
On a quiz that Im using to prepare for my test I made a 1.32 poin.pdfOn a quiz that Im using to prepare for my test I made a 1.32 poin.pdf
On a quiz that Im using to prepare for my test I made a 1.32 poin.pdf
 
Genomics of cold-adapted microorganisms
Genomics of cold-adapted microorganismsGenomics of cold-adapted microorganisms
Genomics of cold-adapted microorganisms
 
Humans Aliens And E Harmony Or Why There Is No Such Thing As A Free Lunch In ...
Humans Aliens And E Harmony Or Why There Is No Such Thing As A Free Lunch In ...Humans Aliens And E Harmony Or Why There Is No Such Thing As A Free Lunch In ...
Humans Aliens And E Harmony Or Why There Is No Such Thing As A Free Lunch In ...
 
SF Big Analytics20170706: What the brain tells us about the future of streami...
SF Big Analytics20170706: What the brain tells us about the future of streami...SF Big Analytics20170706: What the brain tells us about the future of streami...
SF Big Analytics20170706: What the brain tells us about the future of streami...
 

Recently uploaded

Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers:  A Deep Dive into Serverless Spatial Data and FMECloud Frontiers:  A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
Safe Software
 
Architecting Cloud Native Applications
Architecting Cloud Native ApplicationsArchitecting Cloud Native Applications
Architecting Cloud Native Applications
WSO2
 
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers:  A Deep Dive into Serverless Spatial Data and FMECloud Frontiers:  A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
Safe Software
 

Recently uploaded (20)

Apidays New York 2024 - APIs in 2030: The Risk of Technological Sleepwalk by ...
Apidays New York 2024 - APIs in 2030: The Risk of Technological Sleepwalk by ...Apidays New York 2024 - APIs in 2030: The Risk of Technological Sleepwalk by ...
Apidays New York 2024 - APIs in 2030: The Risk of Technological Sleepwalk by ...
 
MINDCTI Revenue Release Quarter One 2024
MINDCTI Revenue Release Quarter One 2024MINDCTI Revenue Release Quarter One 2024
MINDCTI Revenue Release Quarter One 2024
 
MS Copilot expands with MS Graph connectors
MS Copilot expands with MS Graph connectorsMS Copilot expands with MS Graph connectors
MS Copilot expands with MS Graph connectors
 
Apidays New York 2024 - The Good, the Bad and the Governed by David O'Neill, ...
Apidays New York 2024 - The Good, the Bad and the Governed by David O'Neill, ...Apidays New York 2024 - The Good, the Bad and the Governed by David O'Neill, ...
Apidays New York 2024 - The Good, the Bad and the Governed by David O'Neill, ...
 
EMPOWERMENT TECHNOLOGY GRADE 11 QUARTER 2 REVIEWER
EMPOWERMENT TECHNOLOGY GRADE 11 QUARTER 2 REVIEWEREMPOWERMENT TECHNOLOGY GRADE 11 QUARTER 2 REVIEWER
EMPOWERMENT TECHNOLOGY GRADE 11 QUARTER 2 REVIEWER
 
How to Troubleshoot Apps for the Modern Connected Worker
How to Troubleshoot Apps for the Modern Connected WorkerHow to Troubleshoot Apps for the Modern Connected Worker
How to Troubleshoot Apps for the Modern Connected Worker
 
Exploring Multimodal Embeddings with Milvus
Exploring Multimodal Embeddings with MilvusExploring Multimodal Embeddings with Milvus
Exploring Multimodal Embeddings with Milvus
 
ICT role in 21st century education and its challenges
ICT role in 21st century education and its challengesICT role in 21st century education and its challenges
ICT role in 21st century education and its challenges
 
Strategies for Landing an Oracle DBA Job as a Fresher
Strategies for Landing an Oracle DBA Job as a FresherStrategies for Landing an Oracle DBA Job as a Fresher
Strategies for Landing an Oracle DBA Job as a Fresher
 
Apidays New York 2024 - Scaling API-first by Ian Reasor and Radu Cotescu, Adobe
Apidays New York 2024 - Scaling API-first by Ian Reasor and Radu Cotescu, AdobeApidays New York 2024 - Scaling API-first by Ian Reasor and Radu Cotescu, Adobe
Apidays New York 2024 - Scaling API-first by Ian Reasor and Radu Cotescu, Adobe
 
TrustArc Webinar - Unlock the Power of AI-Driven Data Discovery
TrustArc Webinar - Unlock the Power of AI-Driven Data DiscoveryTrustArc Webinar - Unlock the Power of AI-Driven Data Discovery
TrustArc Webinar - Unlock the Power of AI-Driven Data Discovery
 
presentation ICT roal in 21st century education
presentation ICT roal in 21st century educationpresentation ICT roal in 21st century education
presentation ICT roal in 21st century education
 
Apidays New York 2024 - Accelerating FinTech Innovation by Vasa Krishnan, Fin...
Apidays New York 2024 - Accelerating FinTech Innovation by Vasa Krishnan, Fin...Apidays New York 2024 - Accelerating FinTech Innovation by Vasa Krishnan, Fin...
Apidays New York 2024 - Accelerating FinTech Innovation by Vasa Krishnan, Fin...
 
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers:  A Deep Dive into Serverless Spatial Data and FMECloud Frontiers:  A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
 
Strategize a Smooth Tenant-to-tenant Migration and Copilot Takeoff
Strategize a Smooth Tenant-to-tenant Migration and Copilot TakeoffStrategize a Smooth Tenant-to-tenant Migration and Copilot Takeoff
Strategize a Smooth Tenant-to-tenant Migration and Copilot Takeoff
 
Architecting Cloud Native Applications
Architecting Cloud Native ApplicationsArchitecting Cloud Native Applications
Architecting Cloud Native Applications
 
Navigating the Deluge_ Dubai Floods and the Resilience of Dubai International...
Navigating the Deluge_ Dubai Floods and the Resilience of Dubai International...Navigating the Deluge_ Dubai Floods and the Resilience of Dubai International...
Navigating the Deluge_ Dubai Floods and the Resilience of Dubai International...
 
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers:  A Deep Dive into Serverless Spatial Data and FMECloud Frontiers:  A Deep Dive into Serverless Spatial Data and FME
Cloud Frontiers: A Deep Dive into Serverless Spatial Data and FME
 
Axa Assurance Maroc - Insurer Innovation Award 2024
Axa Assurance Maroc - Insurer Innovation Award 2024Axa Assurance Maroc - Insurer Innovation Award 2024
Axa Assurance Maroc - Insurer Innovation Award 2024
 
Connector Corner: Accelerate revenue generation using UiPath API-centric busi...
Connector Corner: Accelerate revenue generation using UiPath API-centric busi...Connector Corner: Accelerate revenue generation using UiPath API-centric busi...
Connector Corner: Accelerate revenue generation using UiPath API-centric busi...
 

Dr. Randal Koene: Substrate-Independent Minds (Australian Singularity Summit 2012)

Editor's Notes

  1. General concept of demux tree Specific implementation via nanowires, Rudolpho Llinas NYU School of Med, 500nm polymer or platinum wires
  2. General concept of demux tree Specific implementation via nanowires, Rudolpho Llinas NYU School of Med, 500nm polymer or platinum wires
  3. You choose a modeling resolution At it and below, functional characterization is key; the components must be simple enough to capture all their relevant behavior Above it, structural characterization is key; the interaction of components and their emergent product; connectome Function-structure in neuronal networks, and hardware/software – both are actually very similar in any other complex system, including computers You can use concurrent functional characterization and low-res structural information (e.g. finding all neurons) to infer functional connectivity – but there is risk of missing latent functions You can reduce the signal dimensions – considering only spatial architectural information (morphology) instead of spatial and temporal information (responses) by combining high-res structural information with inference of “functional type” - but even with a complete library of types and their paramter-related distributions of behaviors, there there is risk that mapping may not be one-to-one and that spatial data errors (e.g. misreadings of component sizes) may be cumulative and may be hard to correct without the addition of locally gathered functional information It is also better in general to rebuild a complex system bit by bit, while carrying out validation that it still works
  4. Red blood cell diameter 8um. Existing biopassive & bioactive coatings for neural implants. Passes through every capillary to every neuron in the brain. Chip in cell has been done Artificial red blood cell has been done
  5. Teams: Hub cell (8um), sensor, stimulation, herding, chains, tag delivery, morphology recording agents (1-2um)