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A semantic
         information system for
                           Healthcare
    Dr. Peter Scholten the Netherlands
                          Dr. Ji Jie China*
* In cooperation with Prof. Rung Ching Chen, Chaoyang University of Technology, Taiwan
Semantic is the study of meaning (within some context).


Semantic web:
The Semantic Web is a system that enables machines to
"understand" and respond to complex human requests
based on their meaning.


Semantic information system for Healthcare:
Is a semantic web system based on an ontology for
Healthcare.
efficiency



                                          effectivity
               prevention
       costs




                Healthy     Sick            Better

Influence prevention, efficiency and effectivity on costs
Loketgezondleven.nl

Nationale Atlas Volksgezondheid
An Ontology
• Defines
   – a common vocabulary
   – a shared understanding
   – re-use of domain knowledge.

• Is an explicit description of a domain:
   – Concepts (classes, subclasses and superclasses)
   – properties and attributes of concepts
   – constraints on properties and attributes
   – Individuals (often, but not always)
- Protégé: an ontology editor
     • RDF
                       • RDFS
     • OWL             • SPARQL
     • SWRL            • SQWRL
     • DLQuery

- W3C

- OWL Generator (incl. Restful service
  based on list, rules and urls)
the book has a title with value "Javascript"
the book has a title with value "Javascript"




  Subject             property             object




This is the essence of RDF: the (s,p,o) triple

Any expression in RDF is a collection of triples
An ontology describes the concepts in the domain and also the
relationships that hold between those concepts.
Person            Married with


Peter               Roos

Jan                 Marleen




         Person Jan is Married with Marleen.

         With who is Marleen married ?
Diseases                         Symptoms
                      hasSymptom




class                 isSymptomOf              class

          An inverse property:
          hasSymptom is inverse of isSymptomOf
OWL
properties
Symptom 1


disease
          Symptom 2


          Symptom 3
Select symptom



disease   Candidate symptom




          Candidate symptom
Select symptom



disease 1   Candidate symptom




disease 2   Select symptom



            Candidate symptom
url1    Select symptom



disease 1   url2
                   url3    Candidate symptom




disease 2   url4
            url4    url5   Select symptom



                   url6    Candidate symptom
Symptom checker

What can be wrong with me,
I feel drye throut.

                 query




                  result
Candidate
                              Disease 1                symptom
Do you have one or more of
the next symptoms             Disease 2
                                                       Select
                                                       symptom

                                                       Candidate
                                                       symptom




    Symptoms of Laryngitis   Symptoms of sore-throat
Prevention               Diseases                    Causes
                                                                                Health
                                                                             Improvement

     Patient
                              Symptom
                                                                               Shared
                                                                             experiences
                                                         No treatment
    Influence factor
                              Treatment
                                                                              Individu

          Self treatment                                   Orthose
                                  Specialist
                                                                             Suppliers
Allergy
                               “repaired”                 Prothese

                 Medicine
                                               Address
                                                             Qualification


                            Semantic health care system
Question: Can I use medicine for it?


Query: Medicines and canCure value Laryngitis

Answer: No medicine found

Suggestion: Look at Url1, Url2, … or contact your doctor
Question: Where can I find a good family doctor?

Query: Professionals and hasProfession value family doctor
Complex example

Question: What can be wrong with me, I feel fatigue.

Query: Diseases and hasSymptoms value “fatique”
158 diseases found
Symptom checker
Fatigue + Extreme-hunger           => ‘Possible’ Diabetes
By interaction with symptom checker:




                                          => High risk Diabetes
Conclusion:

Some symptoms are so vague or
complex (relations with more diseases)
or in cases of multimorbidity
that using a Symptom Checker
can improve the quality of
the diagnoses.
Question: What kind of medicine can help me?


Query: Medicines and canCure value Diabetes
Decision Support System
Traditional approach



Semantic
                    Query Constructor
Application
                    Natural language
Health Care



   Semantic approach
NLP processor


              Start / end class
 Problem      based on k-nearest
              neighbour classifier




 Question       Calculate route



              Feedback by expert



                      Query


Fine tuning
Demo:

• Symptom Checker

• Decision Support System

• Query constructor based on NLP

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Semantic healthcare

  • 1. A semantic information system for Healthcare Dr. Peter Scholten the Netherlands Dr. Ji Jie China* * In cooperation with Prof. Rung Ching Chen, Chaoyang University of Technology, Taiwan
  • 2. Semantic is the study of meaning (within some context). Semantic web: The Semantic Web is a system that enables machines to "understand" and respond to complex human requests based on their meaning. Semantic information system for Healthcare: Is a semantic web system based on an ontology for Healthcare.
  • 3. efficiency effectivity prevention costs Healthy Sick Better Influence prevention, efficiency and effectivity on costs
  • 5. An Ontology • Defines – a common vocabulary – a shared understanding – re-use of domain knowledge. • Is an explicit description of a domain: – Concepts (classes, subclasses and superclasses) – properties and attributes of concepts – constraints on properties and attributes – Individuals (often, but not always)
  • 6. - Protégé: an ontology editor • RDF • RDFS • OWL • SPARQL • SWRL • SQWRL • DLQuery - W3C - OWL Generator (incl. Restful service based on list, rules and urls)
  • 7. the book has a title with value "Javascript"
  • 8. the book has a title with value "Javascript" Subject property object This is the essence of RDF: the (s,p,o) triple Any expression in RDF is a collection of triples
  • 9. An ontology describes the concepts in the domain and also the relationships that hold between those concepts.
  • 10. Person Married with Peter Roos Jan Marleen Person Jan is Married with Marleen. With who is Marleen married ?
  • 11. Diseases Symptoms hasSymptom class isSymptomOf class An inverse property: hasSymptom is inverse of isSymptomOf
  • 13. Symptom 1 disease Symptom 2 Symptom 3
  • 14. Select symptom disease Candidate symptom Candidate symptom
  • 15. Select symptom disease 1 Candidate symptom disease 2 Select symptom Candidate symptom
  • 16. url1 Select symptom disease 1 url2 url3 Candidate symptom disease 2 url4 url4 url5 Select symptom url6 Candidate symptom
  • 17. Symptom checker What can be wrong with me, I feel drye throut. query result
  • 18. Candidate Disease 1 symptom Do you have one or more of the next symptoms Disease 2 Select symptom Candidate symptom Symptoms of Laryngitis Symptoms of sore-throat
  • 19. Prevention Diseases Causes Health Improvement Patient Symptom Shared experiences No treatment Influence factor Treatment Individu Self treatment Orthose Specialist Suppliers Allergy “repaired” Prothese Medicine Address Qualification Semantic health care system
  • 20. Question: Can I use medicine for it? Query: Medicines and canCure value Laryngitis Answer: No medicine found Suggestion: Look at Url1, Url2, … or contact your doctor
  • 21. Question: Where can I find a good family doctor? Query: Professionals and hasProfession value family doctor
  • 22. Complex example Question: What can be wrong with me, I feel fatigue. Query: Diseases and hasSymptoms value “fatique”
  • 24.
  • 25. Symptom checker Fatigue + Extreme-hunger => ‘Possible’ Diabetes By interaction with symptom checker: => High risk Diabetes
  • 26. Conclusion: Some symptoms are so vague or complex (relations with more diseases) or in cases of multimorbidity that using a Symptom Checker can improve the quality of the diagnoses.
  • 27. Question: What kind of medicine can help me? Query: Medicines and canCure value Diabetes
  • 28.
  • 30. Traditional approach Semantic Query Constructor Application Natural language Health Care Semantic approach
  • 31. NLP processor Start / end class Problem based on k-nearest neighbour classifier Question Calculate route Feedback by expert Query Fine tuning
  • 32. Demo: • Symptom Checker • Decision Support System • Query constructor based on NLP