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Dr. Anupama Karanth
www.ophthalclass.blogspot.com

                     www.ophthalclass.blogspot.com
http://www.djo.harvard.edu/site.php?url=/physicians/gr/1134


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Idiopathic           Infectious       Immune related

• After ruling out   • Tuberculosis,     • Sarcoidosis
  other causes         syphilis          • Vogt – Kayanagi
                     • Lyme disease        – Harada
                     • Leptospirosis       syndrome
                     • Infectious        • Sympathetic
                       endophthalmitis     ophthalmitis
                                         • Beh et
                                           syndrome




                                              www.ophthalclass.blogspot.com
   Anatomical diagnosis – Panuveitis
   Infectious causes –negative tests
   Penetrating injury to the other eye
   Is this the sympathizing eye ?
   SYMPATHETIC OPHTHALMITIS




                                          www.ophthalclass.blogspot.com
http://www.aao.org/publications/eyenet/200804/am_rounds.cfm



                                                   www.ophthalclass.blogspot.com
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   Panuveitis
   Bilateral, granulomatous uveitis
   Chronic and recurrent
   Shallow detachments and depigmentation
   Dark skinned individual
   VOGT-KOYANAGI-HARADA SYNDROME


                                       www.ophthalclass.blogspot.com
www.ophthalclass.blogspot.com
Idiopathic           Infectious       Immune related


• Most common        • Herpes simplex   • HLA B27+/
• Diagnosis only     • Herpes zoster      seronegative
  after other        • Tuberculosis       spondylo-
  causes are ruled                        arthropathies
                     • Syphilis
  out                                   • Juvenile
                                          rheumatoid
                                          arthritis (JRA)
                                        • Lens or IOL
                                          related


                                              www.ophthalclass.blogspot.com
   Seronegative spondyloarthropathies
    ◦ Ankylosing spondylitis
    ◦ Psoariatic arthritis
    ◦ Reiter syndrome
    ◦ Inflammatory bowel disease

   Usually associated with HLA B27 positivity


                                       www.ophthalclass.blogspot.com
   Young adult male with classic triad of
    ◦ Nonspecific urethritis
    ◦ Polyarthritis
    ◦ Conjunctivitis and iritis




                                   www.ophthalclass.blogspot.com
www.ophthalclass.blogspot.com
   Young adult male with classic triad of
    ◦ Hypopyon iritis
    ◦ Genital ulcers
    ◦ Oral ulcers




                                   www.ophthalclass.blogspot.com
www.ophthalclass.blogspot.com
Idiopathic       Infectious     Immune related

• Less common    • Toxoplasmosis   • Sarcoidosis
                 • Toxocariasis    • Collagen vascular
                 • Herpes            diseases
                  (ARN/PORN/CMV)   • Retinochoroidop
                 • Tuberculosis,     athies
                   syphilis




                                        www.ophthalclass.blogspot.com
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Common Causes of Uveitis Part2