ANSWER TO KCIAPM CYTOLOGY SLIDE SEMINAR JULY 2014

1. Case 7a
Smear for interpretation

4. Case 7a
1. Leukemic Infiltration
2. NHL- T cell Lymphoma
3. Lymphoma/Leukemic Infiltration
4. Adult T cell Lymphoma

5. DIAGNOSIS

6. LYMPHOMA/LEUKEMIC INFILTRATION

9. Case 7b
53y/M, presented with altered sensorium
CSF cytology

12. Case 7b
1. Seizary Syndrome
2. Mets- Duct Ca breast/AML – M7
3. AML – M5/M7
4. Mets – NHL, Anaplastic
5. AML,HCL
6. Hematolymphoid Malignancy
7. Multiple Myeloma

13. 53y/M, Endoscopic biopsy – Adenoca,
signet ring type, Gr III
with H/O distal gastrectomy
(HPE 7492/13 ) – Adenocarcinoma Gr-III
L V emboli +, 7/16 LNs mets.+ ,
Extranodal spread +
Post – Op. CT given
Now presenting with CNS symptoms

14. DIAGNOSIS
Carcinomatous Meningitis

16. Case 8
17y/F presented with h/o
hemiparesis, altered sensorium.
CSF Cytology

21. DIAGNOSIS

22. Case 8
1. 1. Cryptococcal Meningitis
2. Myeloid Precursors – S/o Leukemoid
reaction
3. Positive - ? ALL, ? AML
4. AML with CNS Involvement
5. ?ALL , ?Lymphoma
6. AML – M7
7. Viral Encephelitis

23. Reactive Lymphoid Cells

24. Detection of Leukemic Lymphoblasts in CSF
Is Instrument-Dependent
Alison R. Huppmann, MD,1Susan R.Rheingold,MD,2
L. Charles Bailey, MD,2 Marybeth Helfrich,
BSMT, ASCP,1 and John K. Choi, MD, PhD1,3
Wescor Cytopro showed a 5- to 9-fold increase
in the number of cells retrieved compared with
the equivalent slide from the Shandon CytoSpin
Am J Clin Pathol 2012;137:795-799