This document discusses a talk titled "Large Problems Mostly Solved" given at Djangocon 2010. The talk provides an overview of common problems faced when building web applications and identifies solutions that are well-established ("mostly solved") and problems that still lack good solutions. Examples of "mostly solved" problems discussed include search (via Haystack), documentation (via Sphinx), database migrations (via South), asynchronous tasks (via Celery), remote execution (via Fabric), and deployment (via Gunicorn).