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Patient profile
J.Y.
17 y/o
Single
Roman Catholic
Sta Lucia Agdao,
Davao City
G1P0
Chief Complaint
Profuse vaginal bleeding
OB History
No. Year Sex Indication for
C/S
Place of
Delivery
Attending B
W
Complications
n/a n/a n/a n/a n/a n/a n/a n/a
G1P0
LMP- December 26, 2008 AOG- 18 weeks 3/7
PMP- November 26, 2008 EDC- October 2, 2009
Menarche: 13 y/o
Subsequent Menstrual Period:
regular, lasting for 5 days soaking 1-2 pads/day
Coitarche: 17 y/o, with 1 sexual partner
Papsmear: none
Family Planning Method: none
Gyne history
(+) childhood measles & chickenpox
(-) DM
(-)HPN
(-)BA
 (-)CA
Past Medical Hx
(+) HPN – father
(+) Ovarian Cancer – maternal
(+) Brochial Asthma – patenal side
(-) Heart disease
(-) PTB
(-) DM
Family Hx
Does not smoke
Slight alcoholic beverage drinker
No known food & drug allergies
Fresh graduate from HS
Personal/Social History
Review of Systems
HEENT: No history of head injury, good vision, good
hearing occasional mild colds, occasional canker sores
and no alarming complaints on the bucal cavity and
pharynx
Neck: no pain and difficulty in swallowing, no
complaints of tender lymph nodes
Cardio: no chest pain, no palpitations
Pulmo: no dyspnea, no cough
Gastrointestinal: abdominal pain on the hypogastric
region, no vomiting, claimed to have mild diarrheic
stools, no hematochezia
Urinary: no frequency, no hematuria, no dysuria
Review of Systems
History of Present IllnessHistory of Present Illness
4 months
PTA
(+) vaginal bleeding soaking 2 pads per
day
metrorrhagia
(+) increase in abdominal girth
no associated sings and symtoms
2 months
PTA
(+) metrorrhagia soaking 2 pads per day
(+) palpable abdominal mass between the
symphysis pubis and the umbilicus
no associated sings and symtoms
History of Present IllnessHistory of Present Illness
1 day PTA
Profuse vaginal bleeding
(+) nausea
(+) pallor
Palpable abdominal mass almost at the
level of the umbilicus
Admission
PHYSICAL
EXAMINATION
conscious, coherent, not in
cardiorespiratory distress
BP: 120/80
CR: 70 bpm
RR: 20 cpm
T: 36.8
o
C
Palms warm and dry. no rashes.
Nails without clubbing and
cyanosis.
 Hair of average texture. Scalp without
lesions
Physical Examination
 Conjunctiva pink, anicteric sclerae.
Extraocular movements intact.
 Acuity good. No gross ear deformities,
no ear discharges
Nasal mucosa pink, septum midline.
No sinus tenderness
Physical Examination
Oral mucosa pink. Moist lips and
tongue, no tonsillar enlargement,
pharynx without exudate.
 No palpable masses, No enlargement
of thyroid gland. No carotid bruit,
Trachea midline.
Physical Examination
 symmetrical chest expansion, no
intercostals retraction, equal tactile
fremitus, lung fields are resonant,
vesicular breath sounds w/ no added
adventitious
sounds
adynamic precordium, good S1 and S2, no
murmurs, regular rhythm and normal heart rate.
Symmetric, without masses,
Nipples w/out discharges and retraction.
Physical Examination
flat, Normoactive bowel sounds (16/min)
tympanitic no hepatomegaly or splenomegaly
Palpable abdominal mass at the level of the
umbilicus
Physical Examination
No edema
No varicosities, no ulcers
Physical Examination
Radial Femoral Popliteal Dorsalis
pedis
Posterior
tibial
Right +2 +2 +2 +2 +2
Left +2 +2 +2 +2 +2
alert and cooperative, thought coherent, oriented to
person, place and time.
(+) Nystagmus
 able to do nose pointing and rapid alternating
movements.
Intact cranial nerves
Intact pinprick, light touch, position, and vibration
sensation
Physical Examination
+2 +2 +2 +2
+2 +2
+2 +2
+2 +2
R L
Upper
extremities:
5/5 5/5
Lower
extremities
5/5 5/5
Speculum
Smooth, pinkish cervix with no lesions found
Cervix is non-dilated
Internal Examination
Corpus enlarged to ~20 wks size, fixed
No adnexal mass/tenderness
Pelvic examination
Metrorarrgia
Nausea
pallor
Gradually Increasing abdominal mass
4 months PTA- increase in abdominal girth
2 months PTA- palpable abdominal mass between the symphysis
pubis and the umbilicus
1 day PTA- palpable abdominal mass almost at the level of the umbilicus
No pressure signs and symptoms
Salient Features
Pelvic Examination
Corpus enlarged to ~20 wks size, fixed
Non-dilated cervix
Impression
Pregnancy Uteri G1P0
18 3/7 weeks AOG
Hydatidiform Mole
Differential Diagnosis
Submucous myoma
Ectopic pregnancy
Threatened Abortion
Differential DiagnosisFeatures Patient Submucous
myoma
Ectopic
Pregnancy
Threatened
Abortion
Age/incidence 17 years old >35 years old 2% 15%*
Metrorrargia (+) (-) * (+/-) * (+)
abdominal
mass
(+) (+) * (+) * (+)
Pressure
signs and
symptoms
(-) (+)* (-) (+/-)
Nausea and
pallor
(+) (+/-) (+) (+/-)
Pain (-) (+/-) (+) * (+)
Enlarged
globular
corpus
(+)
20 weeks
AOG
(+) * (+/-) (+)
Cervical
dilatation
(+) (+) (+) (+)*
Differential Diagnosis
Features Patient H-mole
Age/incidence 17 years old 1 0f 1500 pregnancies
Metrorrargia (+) (+)
abdominal mass (+) (+)
Pressure signs and
symptoms
(-) (-)
Nausea and pallor (+) (+) *
Pain (-) (-)
Enlarged globular corpus (+) 20 weeks AOG (+) *
Non-dilated cervix (+) (-)
Management
Diagnostic studies:
Quantitative B-hCG
Transvaginal Ultrasound
Dilation and suction curettage
IV oxytocin should be administered
Follow-up for development of GTT
hCG determinations (48 hours, 3 consecutive weeks, every 6
months, and then yearly)
PE (Pelvic exam at regular intervals)
Birth control (1 year- OCP, Depo Provera)
Discussion
H-mole
Molar pregnancy is characterized histologically by
abnormalities of the chorionic villi that consist of
trophoblastic proliferation and edema of villous
stroma
2 forms: Complete & Partial
Discussion
COMPLETE
1. Hydropic degeneration and swelling
of the villous stroma
2. Absence of blood vessels in the
swollen villi.
3. Proliferation of the trophoblastic
epithelium to a varying degree
4. Absence of fetus and amnion.
Management
Dilatation and Suction curettage
bHCG monitoring
Good day

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Case presentation ob

  • 1.
  • 2. Patient profile J.Y. 17 y/o Single Roman Catholic Sta Lucia Agdao, Davao City G1P0
  • 4. OB History No. Year Sex Indication for C/S Place of Delivery Attending B W Complications n/a n/a n/a n/a n/a n/a n/a n/a G1P0 LMP- December 26, 2008 AOG- 18 weeks 3/7 PMP- November 26, 2008 EDC- October 2, 2009
  • 5. Menarche: 13 y/o Subsequent Menstrual Period: regular, lasting for 5 days soaking 1-2 pads/day Coitarche: 17 y/o, with 1 sexual partner Papsmear: none Family Planning Method: none Gyne history
  • 6. (+) childhood measles & chickenpox (-) DM (-)HPN (-)BA  (-)CA Past Medical Hx
  • 7. (+) HPN – father (+) Ovarian Cancer – maternal (+) Brochial Asthma – patenal side (-) Heart disease (-) PTB (-) DM Family Hx
  • 8. Does not smoke Slight alcoholic beverage drinker No known food & drug allergies Fresh graduate from HS Personal/Social History
  • 9. Review of Systems HEENT: No history of head injury, good vision, good hearing occasional mild colds, occasional canker sores and no alarming complaints on the bucal cavity and pharynx Neck: no pain and difficulty in swallowing, no complaints of tender lymph nodes Cardio: no chest pain, no palpitations
  • 10. Pulmo: no dyspnea, no cough Gastrointestinal: abdominal pain on the hypogastric region, no vomiting, claimed to have mild diarrheic stools, no hematochezia Urinary: no frequency, no hematuria, no dysuria Review of Systems
  • 11. History of Present IllnessHistory of Present Illness 4 months PTA (+) vaginal bleeding soaking 2 pads per day metrorrhagia (+) increase in abdominal girth no associated sings and symtoms 2 months PTA (+) metrorrhagia soaking 2 pads per day (+) palpable abdominal mass between the symphysis pubis and the umbilicus no associated sings and symtoms
  • 12. History of Present IllnessHistory of Present Illness 1 day PTA Profuse vaginal bleeding (+) nausea (+) pallor Palpable abdominal mass almost at the level of the umbilicus Admission
  • 14. conscious, coherent, not in cardiorespiratory distress BP: 120/80 CR: 70 bpm RR: 20 cpm T: 36.8 o C
  • 15. Palms warm and dry. no rashes. Nails without clubbing and cyanosis.  Hair of average texture. Scalp without lesions
  • 16. Physical Examination  Conjunctiva pink, anicteric sclerae. Extraocular movements intact.  Acuity good. No gross ear deformities, no ear discharges Nasal mucosa pink, septum midline. No sinus tenderness
  • 17. Physical Examination Oral mucosa pink. Moist lips and tongue, no tonsillar enlargement, pharynx without exudate.  No palpable masses, No enlargement of thyroid gland. No carotid bruit, Trachea midline.
  • 18. Physical Examination  symmetrical chest expansion, no intercostals retraction, equal tactile fremitus, lung fields are resonant, vesicular breath sounds w/ no added adventitious sounds
  • 19. adynamic precordium, good S1 and S2, no murmurs, regular rhythm and normal heart rate. Symmetric, without masses, Nipples w/out discharges and retraction. Physical Examination
  • 20. flat, Normoactive bowel sounds (16/min) tympanitic no hepatomegaly or splenomegaly Palpable abdominal mass at the level of the umbilicus Physical Examination
  • 21. No edema No varicosities, no ulcers Physical Examination Radial Femoral Popliteal Dorsalis pedis Posterior tibial Right +2 +2 +2 +2 +2 Left +2 +2 +2 +2 +2
  • 22. alert and cooperative, thought coherent, oriented to person, place and time. (+) Nystagmus  able to do nose pointing and rapid alternating movements. Intact cranial nerves Intact pinprick, light touch, position, and vibration sensation Physical Examination
  • 23. +2 +2 +2 +2 +2 +2 +2 +2 +2 +2 R L Upper extremities: 5/5 5/5 Lower extremities 5/5 5/5
  • 24. Speculum Smooth, pinkish cervix with no lesions found Cervix is non-dilated Internal Examination Corpus enlarged to ~20 wks size, fixed No adnexal mass/tenderness Pelvic examination
  • 25. Metrorarrgia Nausea pallor Gradually Increasing abdominal mass 4 months PTA- increase in abdominal girth 2 months PTA- palpable abdominal mass between the symphysis pubis and the umbilicus 1 day PTA- palpable abdominal mass almost at the level of the umbilicus No pressure signs and symptoms Salient Features Pelvic Examination Corpus enlarged to ~20 wks size, fixed Non-dilated cervix
  • 26. Impression Pregnancy Uteri G1P0 18 3/7 weeks AOG Hydatidiform Mole
  • 27.
  • 28. Differential Diagnosis Submucous myoma Ectopic pregnancy Threatened Abortion
  • 29. Differential DiagnosisFeatures Patient Submucous myoma Ectopic Pregnancy Threatened Abortion Age/incidence 17 years old >35 years old 2% 15%* Metrorrargia (+) (-) * (+/-) * (+) abdominal mass (+) (+) * (+) * (+) Pressure signs and symptoms (-) (+)* (-) (+/-) Nausea and pallor (+) (+/-) (+) (+/-) Pain (-) (+/-) (+) * (+) Enlarged globular corpus (+) 20 weeks AOG (+) * (+/-) (+) Cervical dilatation (+) (+) (+) (+)*
  • 30. Differential Diagnosis Features Patient H-mole Age/incidence 17 years old 1 0f 1500 pregnancies Metrorrargia (+) (+) abdominal mass (+) (+) Pressure signs and symptoms (-) (-) Nausea and pallor (+) (+) * Pain (-) (-) Enlarged globular corpus (+) 20 weeks AOG (+) * Non-dilated cervix (+) (-)
  • 31. Management Diagnostic studies: Quantitative B-hCG Transvaginal Ultrasound Dilation and suction curettage IV oxytocin should be administered Follow-up for development of GTT hCG determinations (48 hours, 3 consecutive weeks, every 6 months, and then yearly) PE (Pelvic exam at regular intervals) Birth control (1 year- OCP, Depo Provera)
  • 32. Discussion H-mole Molar pregnancy is characterized histologically by abnormalities of the chorionic villi that consist of trophoblastic proliferation and edema of villous stroma 2 forms: Complete & Partial
  • 33. Discussion COMPLETE 1. Hydropic degeneration and swelling of the villous stroma 2. Absence of blood vessels in the swollen villi. 3. Proliferation of the trophoblastic epithelium to a varying degree 4. Absence of fetus and amnion.
  • 34.
  • 35. Management Dilatation and Suction curettage bHCG monitoring