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Gamma Cameras
   David S. Graff PhD
Contact Information


• David S. Graff PhD
• David.S.Graff@gMail.com
• http://GraffNucMed.blogspot.com
Review of
                How a gamma
Scintillation
                camera works
cameras




  Artifacts        Collimators
Review of
                How a gamma
Scintillation
                camera works
cameras




  Artifacts        Collimators
A Gamma Camera is a giant
souped-up scintillation camera
A Gamma Camera is a giant
souped-up scintillation camera


                  Photomultiplier Tube
   Scintillator
                         PMT
Some photons pass through the scintillator
some drop all their energy
some scatter out and deposit some energy
Deposited energy is converted to visible light by
scintilator
Amount of light proportional to deposited energy
Visible light is converted into electrons at surface
of photomultiplier tube
Number of electrons is proportional to amount of
light
Electrons pulled to positively charged plate
Knock more electrons off plate
These electrons pulled towards next plate with more positive voltage
Large number of electrons land on final plate, generate pulse
Size of pulse proportional to number of electrons
Photon deposits energy in scintillator
Size of pulse from PMT proportional to
deposited energy.
A gamma camera is simply a single
large scintillator crystal covered
with photomultiplier tubes.
A scintillator converts the energy into light.
This light is turned into an electic pulse by the PMT.
The height of the electric pulse is proportional to the
total light
Review of
                How a gamma
Scintillation
                camera works
cameras




  Artifacts        Collimators
Anger circuit:
Sum of all outputs measures total light
   = energy of incoming photon: Z
Anger circuit:
Weigted sum of all outputs measures
          position: X+, X-




          X-
Anger circuit:
Weigted sum of all outputs measures
          position: X+, X-




          X+
A scintillator converts the energy into light.
This light is turned into an electic pulse by the PMT.
The height of the electric pulse is proportional to the
total light
The total light collected by all PMTs yields the energy
of the incoming photon.
The position of the photon is the weighted sum of
the signal from the different PMTs.
Weights must be precisely tuned.
Review of
                How a gamma
Scintillation
                camera works
cameras




  Artifacts        Collimators
What if the gain on a
 PMT is too high?
Poor positioning can
lead to non-linearities
A scintillator converts the energy into light.
This light is turned into an electic pulse by the PMT.
The height of the electric pulse is proportional to the
total light

The total light collected by all PMTs yields the energy
of the incoming photon.
The position of the photon is the weighted sum of
the signal from the different PMTs.
Weights of each PMT must be precisely tuned.
Miscorrections in position formula can lead to PMTs
visible in flood image
Technologist responsible for examining daily flood for
echos of PMTs
Review of
                How a gamma
Scintillation
                camera works
cameras




  Artifacts        Collimators
Collimators

For a camera to work, we need to be able to reconstruct
           where the gamma ray came from.

             Gamma rays can’t be focussed
Pinhole Collimator
A pinhole collimator only lets in
photons that pass through the small
  hole. The rest are thrown away.
Pinhole collimators can magnify a
  small object by moving close.
Parallel collimator
Collimators only pass rays
 in a small set of angles
How collimators work
                           Most photons are
                         blocked by collimator       Only photons
Radioactive tracer
                                                      parallel to
   only goes to
                                                    collimator pass
  certain tissues
                                                        through




                                                   Detector sees
     Photons emitted                             blurred projection
    in every direction                           of tracer in patient
Collimators are defined by
    the following characteristics:




                                     Collimator length
                                             l
Septal Thickness   Hole Diameter
        a                d
Acceptance angle is d/l
Bigger d, wider angle
Shorter l, wider angle
A scintillator converts the energy into light.
This light is turned into an electic pulse by the PMT.
The height of the electric pulse is proportional to the
total light

The total light collected by all PMTs yields the energy
of the incoming photon.
The position of the photon is the weighted sum of
the signal from the different PMTs.
Weights of each PMT must be precisely tuned.
Miscorrections in position formula can lead to PMTs
visible in flood image
Technologist responsible for examining daily flood for
echos of PMTs
Collimators absorb nearly all photons.
Pinhole collimators can magnify, useful for small
objects.
Parallel collimators are most common, only let in
photons coming from single direction
Scatter can reduce
     contrast
Idealized Gamma-Ray Spectrum
            in NaI   theoretical

 Counts
  per
 Energy
Interval



           Actual



                    Energy   Eo
Too wide a window adds scattered
  photons and reduces contrast

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Gamma Cameras

  • 1. Gamma Cameras David S. Graff PhD
  • 2. Contact Information • David S. Graff PhD • David.S.Graff@gMail.com • http://GraffNucMed.blogspot.com
  • 3. Review of How a gamma Scintillation camera works cameras Artifacts Collimators
  • 4. Review of How a gamma Scintillation camera works cameras Artifacts Collimators
  • 5. A Gamma Camera is a giant souped-up scintillation camera
  • 6.
  • 7. A Gamma Camera is a giant souped-up scintillation camera Photomultiplier Tube Scintillator PMT
  • 8. Some photons pass through the scintillator some drop all their energy some scatter out and deposit some energy
  • 9. Deposited energy is converted to visible light by scintilator Amount of light proportional to deposited energy
  • 10. Visible light is converted into electrons at surface of photomultiplier tube Number of electrons is proportional to amount of light
  • 11. Electrons pulled to positively charged plate Knock more electrons off plate These electrons pulled towards next plate with more positive voltage Large number of electrons land on final plate, generate pulse Size of pulse proportional to number of electrons
  • 12. Photon deposits energy in scintillator Size of pulse from PMT proportional to deposited energy.
  • 13. A gamma camera is simply a single large scintillator crystal covered with photomultiplier tubes.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18. A scintillator converts the energy into light. This light is turned into an electic pulse by the PMT. The height of the electric pulse is proportional to the total light
  • 19. Review of How a gamma Scintillation camera works cameras Artifacts Collimators
  • 20.
  • 21.
  • 22.
  • 23. Anger circuit: Sum of all outputs measures total light = energy of incoming photon: Z
  • 24. Anger circuit: Weigted sum of all outputs measures position: X+, X- X-
  • 25. Anger circuit: Weigted sum of all outputs measures position: X+, X- X+
  • 26. A scintillator converts the energy into light. This light is turned into an electic pulse by the PMT. The height of the electric pulse is proportional to the total light The total light collected by all PMTs yields the energy of the incoming photon. The position of the photon is the weighted sum of the signal from the different PMTs. Weights must be precisely tuned.
  • 27. Review of How a gamma Scintillation camera works cameras Artifacts Collimators
  • 28. What if the gain on a PMT is too high?
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34. Poor positioning can lead to non-linearities
  • 35.
  • 36.
  • 37. A scintillator converts the energy into light. This light is turned into an electic pulse by the PMT. The height of the electric pulse is proportional to the total light The total light collected by all PMTs yields the energy of the incoming photon. The position of the photon is the weighted sum of the signal from the different PMTs. Weights of each PMT must be precisely tuned. Miscorrections in position formula can lead to PMTs visible in flood image Technologist responsible for examining daily flood for echos of PMTs
  • 38. Review of How a gamma Scintillation camera works cameras Artifacts Collimators
  • 39. Collimators For a camera to work, we need to be able to reconstruct where the gamma ray came from. Gamma rays can’t be focussed
  • 41. A pinhole collimator only lets in photons that pass through the small hole. The rest are thrown away.
  • 42. Pinhole collimators can magnify a small object by moving close.
  • 44.
  • 45. Collimators only pass rays in a small set of angles
  • 46. How collimators work Most photons are blocked by collimator Only photons Radioactive tracer parallel to only goes to collimator pass certain tissues through Detector sees Photons emitted blurred projection in every direction of tracer in patient
  • 47. Collimators are defined by the following characteristics: Collimator length l Septal Thickness Hole Diameter a d
  • 51. A scintillator converts the energy into light. This light is turned into an electic pulse by the PMT. The height of the electric pulse is proportional to the total light The total light collected by all PMTs yields the energy of the incoming photon. The position of the photon is the weighted sum of the signal from the different PMTs. Weights of each PMT must be precisely tuned. Miscorrections in position formula can lead to PMTs visible in flood image Technologist responsible for examining daily flood for echos of PMTs Collimators absorb nearly all photons. Pinhole collimators can magnify, useful for small objects. Parallel collimators are most common, only let in photons coming from single direction
  • 52. Scatter can reduce contrast
  • 53. Idealized Gamma-Ray Spectrum in NaI theoretical Counts per Energy Interval Actual Energy Eo
  • 54. Too wide a window adds scattered photons and reduces contrast