brief one

2. NUCLEAR MEDICINE inNUCLEAR MEDICINE in
BREAST CANCERBREAST CANCER

3. NM in Breast CANM in Breast CA
Scinti-mammography
Sentinal Lymph Node Detection
Bone Scan
Pet-CT
Radio-nuclide therapies

4. Scinti-mammographyScinti-mammography
 Tc-99m labelled MIBI
Screening role
Reserved for equivocal category of breast
lumps on digital mammography
High sensitivity for detecting malignant
breast lesions

5. Sentinal Lymph Node DetectionSentinal Lymph Node Detection
First node in chain of lymphatic drainage
Very important in decision of extent of
surgery, initial staging, future radiation
therapy planning, outcome estimation.
Radioactive material is injected per-op
and sentinal lymph node is marked by
gamma probe
More sensitive than routine dye tests

6. Bone ScanBone Scan
Initial staging
Re-staging
Treatment response
Detection of critical lesions for palliative
radiotherapy

7. PET ScanPET Scan
Limited use in CA Breast
Utilized in few selective cases
Trials are on for more utility

8. Radio-nuclide TherapiesRadio-nuclide Therapies
Usual bone metastasis of CA breast are
osteoblastic
Wide spread skeletal metastasis,
radionuclide therapy can be offered for
bone pain palliation
Radioactive Strontium and phosphorus
are in common use