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Me and Mine

Team 4
Hai Do, Hari Bysani, Helina Solomon, Olamiji Sofela, Vipul Sonavane
Agenda
 Insights
 Market Analysis
 Current Resources
 The M&M fit
 Impact
 Contact points
 Conclusion
3
Insights

Customers

4
Insights

Customers

Burden
of
Health

Legislation

5
Insights
Margaret – 50





On Micardis®
Recently diagnosed with diabetes
At a risk of stroke
She is worried

Pete - 45 and Suzan – 40

 Pete on Tradjenta®
 Suzan is taking medication for
hypertension.

6
Market Analysis - Getting into specifics

Disease focus

Diabetes

Stroke

Hypertens
ion

 Can co-exist in a single
patient
 Similar
hereditary, environmental
and other modifiable risk
factors

2 or more
family
members
therapy

1 person with
multiple
diseases

Drug
access and
Discount
packages
7
Market Analysis - Situation

Doctor - Patient interaction.
 One dimensional
 Focus on one patient at a time
 Frequent clinic visits
 Patients need more and more support

8
Current Resources - What BI has

Placement:
 Product innovator
 Market leader

Product:
 Aggrenox, Micardis, Pradaxa,
Twynsta
 Jentadueto, Tradjenta
Partners:
 Insurance company
 Healthcare provider
 Distribution channels
 Other partners
9
Business Model

What we have?

What we can do?

• Diabetes
6
• hyperten
sion
drugs
• stroke

Penetrative
Pricing
&
campaigns

Platforms

What we can get?

Develop

• New Market
• Loyalty
• Brand value

10
The M & M Fit

Me And Mine
- A family loyalty program
Events

Discount

Me &
Mine

Newsletter

Partnerships
11
The M & M Fit

Events
 Health Talks
 Diagnostic Campaign

 Health Activities
 Health Campaign
Events

Discou
nt

Me &
Mine

Partner
ships

Newsl
etter

12
The M & M Fit

Discounts
 Discount on 6 medicines

 Base discount for current customer
 Additional discount for family
Events
members
Discou
nt

Me &
Mine

Partner
ships

Newsl
etter

13
The M & M Fit

Partnership
 Partnerships with supermarkets
selling healthy food
 Reward program

 Partnerships Fitness centers
 Discounts
Events

Discou
nt

Me &
Mine

Partner
ships

Newsl
etter

14
The M & M Fit

Newsletter
 Information about disease
 Disease specific diets

 Diet Tips
 Exercise tips
Events

Discou
nt

Me &
Mine

Partner
ships

Newsl
etter

15
Impact

PotentialMarket statistics
 Population with more than one disease
7.14% or 16 million patients

 Capturing just 1% , will be
$36M
revenue generated by M&M program

Diabetes
8.3%
Stroke
2.6%

Hypertension
30.6%

16
Impact

Stakeholders
 Less visits to clinics
 Long term support

Doctors

 Value-add for customers
 Customer loyalty

Pharmacist
 Monetary benefits
 Increase in customer base

Insurers

17
Contact Points

Existing channels
 Pharmacists
 Insurance companies
 Non-profits
 Existing patient assistance programs
Industry
 Upgrade existing savings card users
 Training doctors (CME)
 Educational centers
Media
 TV and Radio
 Social Networking websites
 Health mobile apps
Conclusion

Target
- One family (person) multiple diseases
- One disease multiple persons
Offering
- Me and mine
Costs:
- $ 4.7 million
Revenue generated:
- $36M (1% of potential customer)
- Long term effects

- How ‘do’ able is this?

19
Thank you.

20
Support
Slides
21
IMPACT
Summary:
- The U.S. Pharmaceutical Market Size = $319B
- CAGR of 2.7% for the five-year period 2011 – 2016
- Expensive R&D (19%) and with B.I. (23.5%)
- “Patent cliff” effect that Generic Drug producers
with the Price lower than 90 percent.

Effect:
-In 2012, IRR = 7.2%, against 7.7 and 10.5 in two
preceding years.
-Estimated IRR = 7% in the future – barely
covering cost of capital.
-According, McKinsey’s report, average small
molecular drug has NPV = - $65M
Three diseases and
Products
Three diseases and sales in 2012:
* Diabetes - Tradjenta (expiry – April 24, 2017) – Sales: $151M
* Hypertension - Micardis (expiry – Jan 7 , 2014) – Sales: $640M
* Stroke - Predaxa (expiry – Feb 18, 2018) – Sales: $440M
B.I Market share:
- Diabetes: 0.5% (Tradjenta)
- Hypertension: 3.1% (Micardis)
- Stroke: 1.6% (Predaxa)

23
Word-of-Mouth or Family
Solution
Word-of-mouth:
• At 59 percent, the majority of word-ofmouth conversations occur at
home, whether offline or online.
• Offline conversations occur most
among females, those with a higher
education, older consumers and
married respondents or those living
with a partner.
• Online conversations are more likely
among males and younger
consumers.

24
How to measure the effect of
solution?

Financial Analysis:

• The NPV and IRR are decreasing because the cash flows decline
significantly after “Patents Cliff”.
• What should we do to maintain or increase the these ratios?
 Increase the cash flows (before or after “Patents cliff”)
By Family Solution:
- Approach effectively to new customers,
- Family solution enhances the customers relationship that
decreases the “chunk rate”,
- This is the mutual benefit because customer will get discount
with high quality product and the company is able to “lock – in”
customers,
- We increase the cash flows after and even before “Patent cliff”.
25
Overlapping Market
Segments
Percentage of the U.S. population:
- Diabetes: 8.3%
- Hypertension: 30.6%
- Stroke: 2.6%

-Diabetes + Stroke: 2.01%
-Diabetes + Hypertension: 5.53%
-Hypertension + Stroke: 2.0%
-Diabetes + Hypertension + Stroke: 0.8%
-Overlapping part: 7.14% or 16million
patients
-Assume capture 1% of overlapping
part for new hypertension patients
= 160k new customers x $255 = $36M

Diabetes

Stroke

Hypertension

26
McKinsey Report

27
Report Analysis
Small molecules, history estimated for average drug:

Cash Flows
CASES
Before Patent Cliff After Patent Cliff

Normal
case

0

0

63

96

155

236

272

294

318

370

450

569

642

64

6

-1751

0

0

63

96

155

236

272

294

318

370

450

569

642

193

58

17

5

-1751

Solution
case

-1751

0

0

76

115

186

283

326

353

382

444

540

683

770

231

69

21

6

SUMMARY:

ITEMS

NPV

Normal case

Solution case

($250.43) ($196.05) $114.94

IRR

7.5%

8.1%

10.2%

% Decline After
Patent Cliff

10%

30%

30%

% Increase Before Patent Cliff

20%

28

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BI Business Development

  • 1.
  • 2. Me and Mine Team 4 Hai Do, Hari Bysani, Helina Solomon, Olamiji Sofela, Vipul Sonavane
  • 3. Agenda  Insights  Market Analysis  Current Resources  The M&M fit  Impact  Contact points  Conclusion 3
  • 6. Insights Margaret – 50     On Micardis® Recently diagnosed with diabetes At a risk of stroke She is worried Pete - 45 and Suzan – 40  Pete on Tradjenta®  Suzan is taking medication for hypertension. 6
  • 7. Market Analysis - Getting into specifics Disease focus Diabetes Stroke Hypertens ion  Can co-exist in a single patient  Similar hereditary, environmental and other modifiable risk factors 2 or more family members therapy 1 person with multiple diseases Drug access and Discount packages 7
  • 8. Market Analysis - Situation Doctor - Patient interaction.  One dimensional  Focus on one patient at a time  Frequent clinic visits  Patients need more and more support 8
  • 9. Current Resources - What BI has Placement:  Product innovator  Market leader Product:  Aggrenox, Micardis, Pradaxa, Twynsta  Jentadueto, Tradjenta Partners:  Insurance company  Healthcare provider  Distribution channels  Other partners 9
  • 10. Business Model What we have? What we can do? • Diabetes 6 • hyperten sion drugs • stroke Penetrative Pricing & campaigns Platforms What we can get? Develop • New Market • Loyalty • Brand value 10
  • 11. The M & M Fit Me And Mine - A family loyalty program Events Discount Me & Mine Newsletter Partnerships 11
  • 12. The M & M Fit Events  Health Talks  Diagnostic Campaign  Health Activities  Health Campaign Events Discou nt Me & Mine Partner ships Newsl etter 12
  • 13. The M & M Fit Discounts  Discount on 6 medicines  Base discount for current customer  Additional discount for family Events members Discou nt Me & Mine Partner ships Newsl etter 13
  • 14. The M & M Fit Partnership  Partnerships with supermarkets selling healthy food  Reward program  Partnerships Fitness centers  Discounts Events Discou nt Me & Mine Partner ships Newsl etter 14
  • 15. The M & M Fit Newsletter  Information about disease  Disease specific diets  Diet Tips  Exercise tips Events Discou nt Me & Mine Partner ships Newsl etter 15
  • 16. Impact PotentialMarket statistics  Population with more than one disease 7.14% or 16 million patients  Capturing just 1% , will be $36M revenue generated by M&M program Diabetes 8.3% Stroke 2.6% Hypertension 30.6% 16
  • 17. Impact Stakeholders  Less visits to clinics  Long term support Doctors  Value-add for customers  Customer loyalty Pharmacist  Monetary benefits  Increase in customer base Insurers 17
  • 18. Contact Points Existing channels  Pharmacists  Insurance companies  Non-profits  Existing patient assistance programs Industry  Upgrade existing savings card users  Training doctors (CME)  Educational centers Media  TV and Radio  Social Networking websites  Health mobile apps
  • 19. Conclusion Target - One family (person) multiple diseases - One disease multiple persons Offering - Me and mine Costs: - $ 4.7 million Revenue generated: - $36M (1% of potential customer) - Long term effects - How ‘do’ able is this? 19
  • 22. IMPACT Summary: - The U.S. Pharmaceutical Market Size = $319B - CAGR of 2.7% for the five-year period 2011 – 2016 - Expensive R&D (19%) and with B.I. (23.5%) - “Patent cliff” effect that Generic Drug producers with the Price lower than 90 percent. Effect: -In 2012, IRR = 7.2%, against 7.7 and 10.5 in two preceding years. -Estimated IRR = 7% in the future – barely covering cost of capital. -According, McKinsey’s report, average small molecular drug has NPV = - $65M
  • 23. Three diseases and Products Three diseases and sales in 2012: * Diabetes - Tradjenta (expiry – April 24, 2017) – Sales: $151M * Hypertension - Micardis (expiry – Jan 7 , 2014) – Sales: $640M * Stroke - Predaxa (expiry – Feb 18, 2018) – Sales: $440M B.I Market share: - Diabetes: 0.5% (Tradjenta) - Hypertension: 3.1% (Micardis) - Stroke: 1.6% (Predaxa) 23
  • 24. Word-of-Mouth or Family Solution Word-of-mouth: • At 59 percent, the majority of word-ofmouth conversations occur at home, whether offline or online. • Offline conversations occur most among females, those with a higher education, older consumers and married respondents or those living with a partner. • Online conversations are more likely among males and younger consumers. 24
  • 25. How to measure the effect of solution? Financial Analysis: • The NPV and IRR are decreasing because the cash flows decline significantly after “Patents Cliff”. • What should we do to maintain or increase the these ratios?  Increase the cash flows (before or after “Patents cliff”) By Family Solution: - Approach effectively to new customers, - Family solution enhances the customers relationship that decreases the “chunk rate”, - This is the mutual benefit because customer will get discount with high quality product and the company is able to “lock – in” customers, - We increase the cash flows after and even before “Patent cliff”. 25
  • 26. Overlapping Market Segments Percentage of the U.S. population: - Diabetes: 8.3% - Hypertension: 30.6% - Stroke: 2.6% -Diabetes + Stroke: 2.01% -Diabetes + Hypertension: 5.53% -Hypertension + Stroke: 2.0% -Diabetes + Hypertension + Stroke: 0.8% -Overlapping part: 7.14% or 16million patients -Assume capture 1% of overlapping part for new hypertension patients = 160k new customers x $255 = $36M Diabetes Stroke Hypertension 26
  • 28. Report Analysis Small molecules, history estimated for average drug: Cash Flows CASES Before Patent Cliff After Patent Cliff Normal case 0 0 63 96 155 236 272 294 318 370 450 569 642 64 6 -1751 0 0 63 96 155 236 272 294 318 370 450 569 642 193 58 17 5 -1751 Solution case -1751 0 0 76 115 186 283 326 353 382 444 540 683 770 231 69 21 6 SUMMARY: ITEMS NPV Normal case Solution case ($250.43) ($196.05) $114.94 IRR 7.5% 8.1% 10.2% % Decline After Patent Cliff 10% 30% 30% % Increase Before Patent Cliff 20% 28

Editor's Notes

  1. Change the picturesSo we first analyzed the healthcare space. What are the underlying factors that influence health seeking behavior. And we surveyed many Americans, and came to realise that firstly, many elderly didn’t want to know their health status. Its almost as if they had an “ignorance is bliss” attitude (animate words to appear as elaborates). Secondly healthcare was something that was very intimate; and people were only genuinely influenced by their inner circle, well besides their healthcare providers ofcourse. So we are looking at family members here. Thirdly, the patients are becoming increasingly aware about issues and more assertive in behavior, as a whole the market is becoming more discerning when seeking advice.
  2. Then we looked a little more downstream of the customer; sort of what were the experiences after getting all the advice. And we noticed two issues that are inter-related, insurance and cost. Now to illustrate this issue, lets meet Margaret. (play video)
  3. Then we looked a little more downstream of the customer; sort of what were the experiences after getting all the advice. And we noticed two issues that are inter-related, insurance and cost. Now to illustrate this issue, lets meet Margaret. (play video)
  4. Ok, so we know that Hypertension and Diabetes are rather closely inter-related and 2 out of 3 diabetics have hypertension. And in both diabetic & hypertensive patients, there is an increased risk of having a stroke. So there’s a sizeable amount of the population that are currently being treated for more than one of these chronic illnesses. Furthermore, these conditions have familiar predisposition so there may be more than 1 patient in the family.
  5. Traditionally, doctors only treat the patient. They don’t engage the family. There is a one-dimensional interaction and the patient. The patient needs to change their eating habits, exercise regime and other lifestyle choices. However, they lacks the support that is needed to best treat the disease. And then there’s the added financial expenses. So the burden of health wears heavy on the patient.
  6. But what can BI do for them? Well, firstly and perhaps most importantly, BI has the 6 drugs that treat these diseases. Secondly they have partners in the industry, non-profit organisations such as the American Diabetes Association. And a current distribution channel – healthcare providers, pharmacists and distributors.
  7. And they all fall into place in the Me & Mine programme. The family loyalty programme designed to maximise the efficacy of treating a disease. It provides an ecosystem for patients to receive information, alleviates financial cost, holds events for family members to get involved in lifestyle changes and introduces complementing businesses.
  8. Inside core