Us okays world’s 1st device to fight obesity

1. US okays world’s 1st device
to fight obesity
Implant For Those 18 & Above Curbs Appetite By Electrically
Stimulating Stomach Nerves
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A first-of-itskind implant to treat obesity that curbs appetite by
electrically stimulating stomach nerves has been approved in the US.
The Maestro Rechargeable System is approved to treat patients aged
18 and above who have not been able to lose weight with a weight loss
programme, and who have a body mass index of 35 to 45 with at least
one other obesity-linked condition, like type-2 diabetes.
The US Food and Drug Administration (FDA) approved the implant for
certain obese adults, the first weight loss treatment device that targets
the nerve pathway between the brain and the stomach that controls
feelings of hunger and fullness. BMI, which measures body fat based on
an individual's weight and height, is used to define obesity categories.
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According to the Centres for Disease Control and Prevention, more than one-
third of all US adults are obese.
“Medical devices can help physicians and patients develop comprehensive
obesity treatment plans,“ said William Maisel, deputy director for science
and chief scientist at FDA’s Centre for Devices and Radiological Health. The
system consists of a rechargeable electrical pulse generator, wire leads and
electrodes implanted surgically into the abdomen.
It works by sending intermittent electrical pulses to the trunks in the
abdominal vagus nerve, which is involved in regulating stomach emptying
and signalling to the brain that the stomach feels empty or full. Although it is
known that the electric stimulation blocks nerve activity between the brain
and the stomach, the specific mechanisms for we ight loss due to use of the
device are unknown.
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External controllers allow the patient to charge the device and allow
health care professionals to adjust its settings to provide optimal
therapy with minimal side effects.
The safety and effectiveness of the system were evaluated in a clinical
trial that included 233 patients with a BMI of 35 or greater. The study
found that after 12 months, the experimental group lost 8.5% more of
its excess weight than another group which did not receive the active
Maestro device, FDA said.
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