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Stress on the Brain
How Your Brain Responds to
Stress
Did you know that the emotional and
physical responses you have to stress are
set in motion by a series of chemical
releases and reactions? Not all stress is
bad.
“Attack of the Adrenals”-A
Metabolic Story
• The ambulance siren screams it’s warning to get out of the way. You
can’t move your car because you’re stuck in a bumper-to-bumper
traffic jam that reaches as far as the eye can see. There must be an
accident up ahead. Meanwhile the road construction crew a few feet
from your car is jack-hammering the pavement. You are about to
enter the stress zone. Inside your body the alert goes out.
"Attention all parasympathetic forces. Urgent. Adrenal gland
missile silos mounted atop kidneys have just released chemical
cortisol weapons of brain destruction. Mobilize all internal defenses.
Launch immediate counter-calm hormones before hippocampus is
hammered by cortisol."Hormones rush to your adrenal glands to
suppress the streaming cortisol on its way to your brain. Other
hormones rush to your brain to round up all the remnants of cortisol
missles that made it to your hippocampus. These hormones escort
the cortisol remnants back to Kidneyland for a one-way ride on the
Bladderhorn. You have now reached metabolic equilibrium, also
known as homeostasis.
Inside Homeostasis
• When a danger finally passes or the perceived threat is
over, your brain initiates a reverse course of action that
releases a different bevy of biochemicals throughout
your body. Attempting to bring you back into balance,
your brain seeks the holy grail of "homeostasis," that
elusive state of metabolic equilibrium between the
stimulating and the tranquilizing chemical forces in your
body. If either the one of the stimulating or tranquilizing
chemical forces dominates the other without relief, then
you will experience an on-going state of internal
imbalance. This condition is known as stress. And it can
have serious consequences for your brain cells.
Distress Signals from Your Brain
• Your sympathetic nervous system does an excellent job of rapidly preparing
you to deal with what is perceived as a threat to your safety. Its hormones
initiate several metabolic processes that best allow you to cope with sudden
danger. Your adrenal glands release adrenaline (also known as
epinephrine) and other hormones that increase breathing, heart rate, and
blood pressure. This moves more oxygen-rich blood faster to the brain and
to the muscles needed for fighting or fleeing. And, you have plenty of energy
to do either, because adrenaline causes a rapid release of glucose and fatty
acids into your bloodstream. Also, your senses become keener, your
memory sharper, and you are less sensitive to pain. Other hormones shut
down functions unnecessary during the emergency. Growth, reproduction,
and the immune system all go on hold. Blood flow to the skin is reduced.
That's why chronic stress leads to sexual dysfunction, increases your
chances of getting sick, and often manifests as skin ailments.
With your mind and body in this temporary state of metabolic overdrive, you
are now prepared to respond to a life-threatening situation.
Getting Back to Normal
• After a perceived danger has passed, your body
then tries to return to normal. But this may not
be so easy, and becomes even more difficult
with age. Although the hyperactivating
sympathetic nervous system jumps into action
immediately, it is very slow to shut down and
allow the tranquilizing parasympathetic nervous
system to calm things down. Once your stress
response has been activated, the system wisely
keeps you in a state of readiness.
Stress is Not All Bad
• Bear in mind that an appropriate stress response is a
healthy and necessary part of life. One of the things it
does is to release norepinephrine, one of the principal
excitatory neurotransmitters. Norepinephrine is needed
to create new memories. It improves mood. Problems
feel more like challenges, which encourages creative
thinking that stimulates your brain to grow new
connections within itself. Stress management is the key,
not stress elimination. The challenge in this day and age
is to not let the sympathetic nervous system stay
chronically aroused. This may require knowledge of
techniques that work to activate your relaxation
response.
Stress Activates Immune System
(Study)
• Some kinds of acute stress are beneficial. For
example, Ohio State University researchers
found that stress from engaging in a memory
task activated the immune system, whereas the
stress from passively watching a violent video
weakened immunity (as measured by salivary
concentration of SIgA, a major immune
factor). Their results suggest that deadlines and
challenges at work, even if annoying for a short
time, could be a good thing that helps
strengthen the body's defenses.

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Stress

  • 2. How Your Brain Responds to Stress Did you know that the emotional and physical responses you have to stress are set in motion by a series of chemical releases and reactions? Not all stress is bad.
  • 3. “Attack of the Adrenals”-A Metabolic Story • The ambulance siren screams it’s warning to get out of the way. You can’t move your car because you’re stuck in a bumper-to-bumper traffic jam that reaches as far as the eye can see. There must be an accident up ahead. Meanwhile the road construction crew a few feet from your car is jack-hammering the pavement. You are about to enter the stress zone. Inside your body the alert goes out. "Attention all parasympathetic forces. Urgent. Adrenal gland missile silos mounted atop kidneys have just released chemical cortisol weapons of brain destruction. Mobilize all internal defenses. Launch immediate counter-calm hormones before hippocampus is hammered by cortisol."Hormones rush to your adrenal glands to suppress the streaming cortisol on its way to your brain. Other hormones rush to your brain to round up all the remnants of cortisol missles that made it to your hippocampus. These hormones escort the cortisol remnants back to Kidneyland for a one-way ride on the Bladderhorn. You have now reached metabolic equilibrium, also known as homeostasis.
  • 4. Inside Homeostasis • When a danger finally passes or the perceived threat is over, your brain initiates a reverse course of action that releases a different bevy of biochemicals throughout your body. Attempting to bring you back into balance, your brain seeks the holy grail of "homeostasis," that elusive state of metabolic equilibrium between the stimulating and the tranquilizing chemical forces in your body. If either the one of the stimulating or tranquilizing chemical forces dominates the other without relief, then you will experience an on-going state of internal imbalance. This condition is known as stress. And it can have serious consequences for your brain cells.
  • 5. Distress Signals from Your Brain • Your sympathetic nervous system does an excellent job of rapidly preparing you to deal with what is perceived as a threat to your safety. Its hormones initiate several metabolic processes that best allow you to cope with sudden danger. Your adrenal glands release adrenaline (also known as epinephrine) and other hormones that increase breathing, heart rate, and blood pressure. This moves more oxygen-rich blood faster to the brain and to the muscles needed for fighting or fleeing. And, you have plenty of energy to do either, because adrenaline causes a rapid release of glucose and fatty acids into your bloodstream. Also, your senses become keener, your memory sharper, and you are less sensitive to pain. Other hormones shut down functions unnecessary during the emergency. Growth, reproduction, and the immune system all go on hold. Blood flow to the skin is reduced. That's why chronic stress leads to sexual dysfunction, increases your chances of getting sick, and often manifests as skin ailments. With your mind and body in this temporary state of metabolic overdrive, you are now prepared to respond to a life-threatening situation.
  • 6. Getting Back to Normal • After a perceived danger has passed, your body then tries to return to normal. But this may not be so easy, and becomes even more difficult with age. Although the hyperactivating sympathetic nervous system jumps into action immediately, it is very slow to shut down and allow the tranquilizing parasympathetic nervous system to calm things down. Once your stress response has been activated, the system wisely keeps you in a state of readiness.
  • 7. Stress is Not All Bad • Bear in mind that an appropriate stress response is a healthy and necessary part of life. One of the things it does is to release norepinephrine, one of the principal excitatory neurotransmitters. Norepinephrine is needed to create new memories. It improves mood. Problems feel more like challenges, which encourages creative thinking that stimulates your brain to grow new connections within itself. Stress management is the key, not stress elimination. The challenge in this day and age is to not let the sympathetic nervous system stay chronically aroused. This may require knowledge of techniques that work to activate your relaxation response.
  • 8. Stress Activates Immune System (Study) • Some kinds of acute stress are beneficial. For example, Ohio State University researchers found that stress from engaging in a memory task activated the immune system, whereas the stress from passively watching a violent video weakened immunity (as measured by salivary concentration of SIgA, a major immune factor). Their results suggest that deadlines and challenges at work, even if annoying for a short time, could be a good thing that helps strengthen the body's defenses.