Improving Online Access to Drug Related Information

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Improving Online Access to Drug Related Information

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Improving Online Access to Drug Related Information

  1. 1. IMPROVING ONLINE ACCESS TO DRUG-RELATED INFORMATION JIAO LI, RITU KHARE, ZHIYONG LU NCBI/NLM 1 2 SEARCH INTEGRATED ACCESS
  2. 2. 1SEARCH ASSIGNING BRAND NAMES TO DRUG MONOGRAPHS Advil Ibuprofen Mortin Acetaminophen Tylenol Editors describe the drug Consumers use brand information in terms of names as search keywords active ingredient names METHODS: RxNorm Concepts and Relationships • Ingredient Normalization • Dosage Form NormalizationInput: Drug Monograph • Obsolescence Ingredient (IN) has_ingredient Brand Name (BN)Output: Up-to-date Brand names • Reformulation Ibuprofen ingredient_of Advil • Veterinary has_tradename tradename_of Dosage Form (DF) has_dose_form Branded Drug or Package (SBD) Oral Tablet Advil 100 MG Oral Tablet dose_form_of [Obsolete=N] [Veterinary=N]
  3. 3. 2 INTEGRATING DRUG-DISEASEINTEGRATED RELATIONSHIPS FROM MULTIPLE SOURCES ACCESS METHODS: • Filter drug-disease relationships • Statistics-based filter • Domain-knowledge based filter • Rank the disease for each drug • Ranking function based on evidence confidence

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