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Mahrous Article Summary
Cancer Risk in Inflammatory Bowel Disease According to
Patient Phenotype and Treatment - 2013
Wale...
OBJECTIVES
Dr Waleed Kh. Mahrous

 Cancer risk in patients with

inflammatory bowel disease (IBD)
according to IBD phenot...
METHODS
Dr Waleed Kh. Mahrous

 A total of 1,515 patients were

diagnosed with ulcerative colitis
(UC) and 810 with Crohn...
RESULTS
 Patients with UC were not at increased risk of

cancer overall (SIR, 1.12; 95% CI, 0.97–1.28) despite
increased ...
CONCLUSIONS

 Patients with CD, but not

UC, have an overall excess risk
of cancer.

 Clinical characteristics of IBD

p...
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Mahrous Article Summary - 1 - Cancer Risk in Inflammatory Bowel Disease According to Patient Phenotype and Treatment - 2013

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Mahrous Article Summary - 1 - Cancer Risk in Inflammatory Bowel Disease According to Patient Phenotype and Treatment - 2013

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Mahrous Article Summary - 1 - Cancer Risk in Inflammatory Bowel Disease According to Patient Phenotype and Treatment - 2013

  1. 1. Mahrous Article Summary Cancer Risk in Inflammatory Bowel Disease According to Patient Phenotype and Treatment - 2013 Waleed Mahrous Dr Waleed Kh. Mahrous http://www.nature.com/ajg/journal/v108/n12/full/ajg2013249a.html
  2. 2. OBJECTIVES Dr Waleed Kh. Mahrous  Cancer risk in patients with inflammatory bowel disease (IBD) according to IBD phenotype and treatment Dr Waleed Kh. Mahrous http://www.nature.com/ajg/journal/v108/n12/full/ajg2013249a.html
  3. 3. METHODS Dr Waleed Kh. Mahrous  A total of 1,515 patients were diagnosed with ulcerative colitis (UC) and 810 with Crohn’s disease (CD) during 1978–2002.  Patients were followed until 31 December 2010 for occurrence of incident cancer Dr Waleed Kh. Mahrous http://www.nature.com/ajg/journal/v108/n12/full/ajg2013249a.html
  4. 4. RESULTS  Patients with UC were not at increased risk of cancer overall (SIR, 1.12; 95% CI, 0.97–1.28) despite increased risk of prostate cancer (SIR, 1.82; 95% CI, 1.17–2.71).  Patients with CD had a 55% increased risk of cancer - - overall (SIR, 1.55; 95% CI, 1.29–1.84) related to young age Colonic disease Smoking, Thiopurine exposure Dr Waleed Kh. Mahrous http://www.nature.com/ajg/journal/v108/n12/full/ajg2013249a.html
  5. 5. CONCLUSIONS  Patients with CD, but not UC, have an overall excess risk of cancer.  Clinical characteristics of IBD patients at excess risk differ by cancer subtype. Dr Waleed Kh. Mahrous http://www.nature.com/ajg/journal/v108/n12/full/ajg2013249a.html

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