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Dilemma in case of HOCM
Dr. Vivek mandurke
Interventional cardiologist
• 52 yr female
• Hypertensive
• k/c/o HOCM
• Exertional angina CCS class III
• Presented with acute LVF
• ECG : LBBB with QRS – 140 ms
• ECHO
• Pt shifted from periphery hospital with acute LVF
• Managed with Oxygen, Lasix infusion
• Pt improved over 72 hours
• Shifted to ward
• After every meal she use to have tachycardia, dyspnoea and fall in
saturation
• Pt twice shifted to ICU twice as saturation fall below 90
• Pt was on optimised doses of betablockers CCB diuretics
• Pt added on SGLT2 inhibitor
• Still no relief … medical management failed to relieve her symptoms
• We planned to do CAG to rule out any obstructive lesion
Proximal LAD – no septal perforator
Ventriculisaton with 5F catheter so attempt
made to visualise ostium of left main
We thought definitely there is lesion at
ostium of left main
What next …
• Evaluate further this Lesion
• Physiological study vs imaging/ direct stenting
• We opted for FFR with iv adenosine
FFR to left main to LAD
What next….
• We decided to do left main stenting with imaging as confused even
after FFR
• Default strategy was IVUS but machine not working
• Difficult to visualise ostial segment of LM with OCT
• We decided to use TELESCOPE
Ostium of left main looks fairly good with
eccentric plaque
• After looking OCT we abandoned plan of left main stenting
• Limited Literature - FFR in HOCM
Finally decided to go for surgery
Risk for Septal reduction therapy
Intraop TEE before myectomy
Intraop TEE after myectomy
Hushhh…Pt discharged on 7th day of surgery
Echo on discharge
But all izz not well …
• Pt came with acute LVF after 9th day of discharge ...
• Done echo and got surprize
No SAM
Post myectomy VSD ..
Finally decided to go for redo surgery
All izz still not well…
• Pt went into CHB post operative
• Decided to go for permanent pacemaker
Date of admission 10/11/21
Cag 13/11/21
FFR 16/11/21
OCT 19/11/21
Surgical myectomy 25/11/21
Discharged on 1/12/21
Re-admission and Detection of VSR with acute LVF 9/12/21
Dacron Patch closure of VSD 11/12/21
PPMI 18/12/21
Asymptomatic till date …..
Learning points
• Management of HCM is very challenging
• Every ventriculisation is not significant lesion
• Limited literature about FFR in HOCM
• Surgery though better than alcohol septal ablation for long run … still
it is last resort

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dilemma in hocm ].pptx

  • 1. Dilemma in case of HOCM Dr. Vivek mandurke Interventional cardiologist
  • 2. • 52 yr female • Hypertensive • k/c/o HOCM • Exertional angina CCS class III • Presented with acute LVF • ECG : LBBB with QRS – 140 ms • ECHO
  • 3.
  • 4.
  • 5.
  • 6. • Pt shifted from periphery hospital with acute LVF • Managed with Oxygen, Lasix infusion • Pt improved over 72 hours • Shifted to ward • After every meal she use to have tachycardia, dyspnoea and fall in saturation • Pt twice shifted to ICU twice as saturation fall below 90 • Pt was on optimised doses of betablockers CCB diuretics • Pt added on SGLT2 inhibitor • Still no relief … medical management failed to relieve her symptoms
  • 7.
  • 8. • We planned to do CAG to rule out any obstructive lesion
  • 9.
  • 10. Proximal LAD – no septal perforator
  • 11. Ventriculisaton with 5F catheter so attempt made to visualise ostium of left main
  • 12. We thought definitely there is lesion at ostium of left main
  • 13. What next … • Evaluate further this Lesion • Physiological study vs imaging/ direct stenting • We opted for FFR with iv adenosine
  • 14. FFR to left main to LAD
  • 15. What next…. • We decided to do left main stenting with imaging as confused even after FFR • Default strategy was IVUS but machine not working • Difficult to visualise ostial segment of LM with OCT • We decided to use TELESCOPE
  • 16.
  • 17. Ostium of left main looks fairly good with eccentric plaque
  • 18. • After looking OCT we abandoned plan of left main stenting • Limited Literature - FFR in HOCM
  • 19. Finally decided to go for surgery
  • 20. Risk for Septal reduction therapy
  • 21. Intraop TEE before myectomy
  • 22. Intraop TEE after myectomy
  • 23. Hushhh…Pt discharged on 7th day of surgery
  • 25. But all izz not well … • Pt came with acute LVF after 9th day of discharge ... • Done echo and got surprize
  • 27.
  • 28.
  • 30. Finally decided to go for redo surgery
  • 31.
  • 32. All izz still not well… • Pt went into CHB post operative • Decided to go for permanent pacemaker
  • 33.
  • 34. Date of admission 10/11/21 Cag 13/11/21 FFR 16/11/21 OCT 19/11/21 Surgical myectomy 25/11/21 Discharged on 1/12/21 Re-admission and Detection of VSR with acute LVF 9/12/21 Dacron Patch closure of VSD 11/12/21 PPMI 18/12/21 Asymptomatic till date …..
  • 35. Learning points • Management of HCM is very challenging • Every ventriculisation is not significant lesion • Limited literature about FFR in HOCM • Surgery though better than alcohol septal ablation for long run … still it is last resort

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