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Lobular Capillary Haemangioma Pak Armed Forces Med J 2017; 67 (Suppl-1): S117-18
S117
LLOOBBUULLAARR CCAAPPIILLLLAARRYY HHAAEEMMAANNGGIIOOMMAA OOFF VVOOCCAALL CCOORRDD –– AA CCAASSEE RREEPPOORRTT
Farhan Akbar, Tarique Ahmed Maka, Tariq Sarfraz*
Combined Military Hospital Kharian/ National University of Medical Sciences (NUMS) Pakistan, *Army Medical College/ National
University of Medical Science (NUMS) Rawalpindi Pakistan
INTRODUCTION
Lobular capillary haemangioma (Pyogenic
granuloma) is a well-known and commonly
occurring benign vascular lesion of the skin and
mucous membrane especially of oral cavity, but
rarely occurs at other places1. For many years the
lesion was considered to be a reactive or
infective process due to presence of extensive
inflammation and its association with trauma in
about 1/3rd of the cases2. Cawson et al., in
dermatologic literature has described it as
“granuloma telangiectacticum” due to the
presence of numerous blood vessels seen in
histological sections3. Recently it is established
that the lesion appears to be neoplastic in nature
and the underlying process is lobular vascular
proliferation with deep and intravascular
counterparts and is redesignated appropriately as
lobular capillary haemangioma instead of
pyogenic granuloma4.
CASE REPORT
A 16-year-old male patient reported to the
department of Ear, Nose, Throat (ENT) & Head
and Neck Surgery with the chief complaint of
hoarseness. The hoarseness was of insidious
onset, which later became progressive over
duration of one year. He was non-smoker and he
did not give history of intake of any medications.
Routine hemogram and radiograms were found
to be normal. Clinical examination on indirect
laryngoscopy revealed a polypoidal growth on
left vocal cord.
Based on the clinical signs and symptoms, a
provisional diagnosis of vocal nodule was
established. On direct laryngoscopy, a reddish
solitary polypoidal growth was seen on left vocal
cord with distinct border. Growth was located in
the anterior part of the left vocal cord just
reaching to anterior commissure measuring 40
mm × 50 mm in size. The lesion was excised
and tissue was sent in 10% formalin for
histopathological examination. The microscopic
examination revealed a lesion showing
proliferation of capillary sized blood vessels in a
lobular pattern with mild inflammation;
suggesting lobular capillary hemangioma
(pyogenic granuloma). This case was followed up
to date and there has been no recurrence so far.
DISCUSSION
Lobular capillary hemangioma (pyogenic
granuloma) occurs in all age groups, children to
older adult, but are more frequently encountered
in females in their second decade due to
hormonal changes. It usually occurs on the lips,
oral mucosa, tongue and in nasal cavity1.
In addition to these usual sites it can occur at
rare sites also as it occurred in vocal cord in our
case. One case report also showed occurrence of
this lesion in vocal cord5. Few other case reports
also mentioned occurrence of lobular capillary
haemangioma at rare sites. A polypoidal lesion at
unusual sites for lobular capillary haemangioma
like larynx, should also be evaluated with this
lesion included in the list of clinical differential
diagnosis.
CONCLUSION
Lobular capillary haemangioma (pyogenic
granuloma) is a commonly occurring lesion
usually involving skin and mucous membranes
of oral cavity, but can also occur at other places
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which
permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Correspondence: Dr Tarique Ahmed Maka, Registrar ENT
Department CMH Kharian Pakistan (Email: tariqmaka@yahoo.com)
Received: 15 Oct 2015; revised received: 15 Jul 2016; accepted: 19 Jul
2016
Case ReportOpen Access
Lobular Capillary Haemangioma Pak Armed Forces Med J 2017; 67 (Suppl-1): S117-18
S118
like larynx, though rarely. The lesion is now
considered as neoplastic in nature instead of
being reactive or infective process and is
redesignated as lobular capillary haemangioma
instead of pyogenic granuloma.
CONFLICT OF INTEREST
This study has no conflict of interest to
declare by any author.
REFERENCES
1. Calduch L, Ortega C, Navarro V, Martínez E, Molina I, Jordá E.
Verrucous hemangioma: report of two cases and review of the
literature. Pediatr Dermatol. 2000; 17: 213-7.
2. Harris MN, Desai R, Chuang TY, Hood AF, Mirowski GW.
Lobular capillary haemangioma: an epidemiologic case report
with emphasis on cutaneous cases. J Am Acad Dermatol. 2000;
42: 1012-6.
3. Cawson RA, Binnie WH, Seight PM. Lucas pathology of
tumors of oral tissues. 5thed Missouri: Mosby; 1998.p. 252-4
4. Calonji JE, Fletcher DM. Vascular tumours. In: Fletcher DM,
editors. Diagnostic histopathology of tumours. 4th ed
Philadelphia: Elsevier Saunders; 2013.p. 49-50.
5. Rechtman I. Pyogenic granuloma of the vocal cord. Anaesth
Intensive Care. 1983; 11: 81-2.

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LOBULAR CAPILLARY HAEMANGIOMA OF VOCAL CORD – A CASE REPORT

  • 1. Lobular Capillary Haemangioma Pak Armed Forces Med J 2017; 67 (Suppl-1): S117-18 S117 LLOOBBUULLAARR CCAAPPIILLLLAARRYY HHAAEEMMAANNGGIIOOMMAA OOFF VVOOCCAALL CCOORRDD –– AA CCAASSEE RREEPPOORRTT Farhan Akbar, Tarique Ahmed Maka, Tariq Sarfraz* Combined Military Hospital Kharian/ National University of Medical Sciences (NUMS) Pakistan, *Army Medical College/ National University of Medical Science (NUMS) Rawalpindi Pakistan INTRODUCTION Lobular capillary haemangioma (Pyogenic granuloma) is a well-known and commonly occurring benign vascular lesion of the skin and mucous membrane especially of oral cavity, but rarely occurs at other places1. For many years the lesion was considered to be a reactive or infective process due to presence of extensive inflammation and its association with trauma in about 1/3rd of the cases2. Cawson et al., in dermatologic literature has described it as “granuloma telangiectacticum” due to the presence of numerous blood vessels seen in histological sections3. Recently it is established that the lesion appears to be neoplastic in nature and the underlying process is lobular vascular proliferation with deep and intravascular counterparts and is redesignated appropriately as lobular capillary haemangioma instead of pyogenic granuloma4. CASE REPORT A 16-year-old male patient reported to the department of Ear, Nose, Throat (ENT) & Head and Neck Surgery with the chief complaint of hoarseness. The hoarseness was of insidious onset, which later became progressive over duration of one year. He was non-smoker and he did not give history of intake of any medications. Routine hemogram and radiograms were found to be normal. Clinical examination on indirect laryngoscopy revealed a polypoidal growth on left vocal cord. Based on the clinical signs and symptoms, a provisional diagnosis of vocal nodule was established. On direct laryngoscopy, a reddish solitary polypoidal growth was seen on left vocal cord with distinct border. Growth was located in the anterior part of the left vocal cord just reaching to anterior commissure measuring 40 mm × 50 mm in size. The lesion was excised and tissue was sent in 10% formalin for histopathological examination. The microscopic examination revealed a lesion showing proliferation of capillary sized blood vessels in a lobular pattern with mild inflammation; suggesting lobular capillary hemangioma (pyogenic granuloma). This case was followed up to date and there has been no recurrence so far. DISCUSSION Lobular capillary hemangioma (pyogenic granuloma) occurs in all age groups, children to older adult, but are more frequently encountered in females in their second decade due to hormonal changes. It usually occurs on the lips, oral mucosa, tongue and in nasal cavity1. In addition to these usual sites it can occur at rare sites also as it occurred in vocal cord in our case. One case report also showed occurrence of this lesion in vocal cord5. Few other case reports also mentioned occurrence of lobular capillary haemangioma at rare sites. A polypoidal lesion at unusual sites for lobular capillary haemangioma like larynx, should also be evaluated with this lesion included in the list of clinical differential diagnosis. CONCLUSION Lobular capillary haemangioma (pyogenic granuloma) is a commonly occurring lesion usually involving skin and mucous membranes of oral cavity, but can also occur at other places This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Correspondence: Dr Tarique Ahmed Maka, Registrar ENT Department CMH Kharian Pakistan (Email: tariqmaka@yahoo.com) Received: 15 Oct 2015; revised received: 15 Jul 2016; accepted: 19 Jul 2016 Case ReportOpen Access
  • 2. Lobular Capillary Haemangioma Pak Armed Forces Med J 2017; 67 (Suppl-1): S117-18 S118 like larynx, though rarely. The lesion is now considered as neoplastic in nature instead of being reactive or infective process and is redesignated as lobular capillary haemangioma instead of pyogenic granuloma. CONFLICT OF INTEREST This study has no conflict of interest to declare by any author. REFERENCES 1. Calduch L, Ortega C, Navarro V, Martínez E, Molina I, Jordá E. Verrucous hemangioma: report of two cases and review of the literature. Pediatr Dermatol. 2000; 17: 213-7. 2. Harris MN, Desai R, Chuang TY, Hood AF, Mirowski GW. Lobular capillary haemangioma: an epidemiologic case report with emphasis on cutaneous cases. J Am Acad Dermatol. 2000; 42: 1012-6. 3. Cawson RA, Binnie WH, Seight PM. Lucas pathology of tumors of oral tissues. 5thed Missouri: Mosby; 1998.p. 252-4 4. Calonji JE, Fletcher DM. Vascular tumours. In: Fletcher DM, editors. Diagnostic histopathology of tumours. 4th ed Philadelphia: Elsevier Saunders; 2013.p. 49-50. 5. Rechtman I. Pyogenic granuloma of the vocal cord. Anaesth Intensive Care. 1983; 11: 81-2.