1. Factor V
Leiden Stephanie Palmer
Period 4/5 Rieger
http://www.bmj.com/content/313/7065/1127/F1.large.jpg

2. Thesis
•
Factor V Leiden is not a
very commonly used
phrase in the world like
cancer or AIDS.It is a gene
mutation that could

3. Kelly Anne &&

6. Thrombo
•Intravascular
coagulation of
the blood in any
part of the
Definition of Thrombosis." MedicineNet.
MedicineNet, Inc, 1996. Web. 27 Feb.
2011. <http://www.medterms.com/script/main/
art.asp?articlekey=25023
http://spl225.files.wordpress.com/2009/12/dictionary11.jpg

7. What is a Blood
•thrombus
•form when there is
damage to vein
•blood begins to clot if it
stops moving and
becomes stagnant
http://trendsupdates.com/key-molecular-mechanism-of-blood-clotting-discovered/

8. Lets Look at a
Blood Clot Video. HealthLine. Web. 30 Mar. 2011.
<http://www.healthline.com/

9. DVT & P.E’s
DVT & Pulmonary Embolism. Prevent
DVT. Web. 29 Mar. 2011.
<http://www.preventdvt.org/media/
dvt-videos/glassman.aspx>.

10. • “The tongue
like a sharp
knife... kills
without
http://raisingrrl.files.wordpress.com/2009/02/o005-buddha-w-
http://thinkexist.com/quotes/with/keyword/blood/
beads-jade.jpg http://www.ancientsculpturegallery.com/
http://www.buddhistchannel.tv/picture/upload/buddha-leafs.jpg
images/2982.jpg

11. What is Factor
•-Gene mutation, not a
disease
•-Makes patients more likely
to develop a clot
•-Hereditary
•-Factor V gene: protein for
blood to clot properly
•-DVT & Pulmonary Embolus Hamilton Health Science (Aug. 2007). PDF file.
http://topnews.com.sg/images/genes.jpg

12. Obtaining
the Gene
"Heterozygous Factor V Leiden." Chart. Hamilton Health Sciences. N.p., 17 Aug.
2007. Web. 17 Feb. 2011. <http://www.stoptheclot.org/documents/
FactorVLeiden-lw.pdf>.

13. Obtaining the Gene
"Homozygous Factor V Leiden." Chart. Hamilton Health Sciences. N.p., 17 Aug.
2007. Web. 17 Feb. 2011.

14. h l
s
A y
e t
c o
S
t

15. How to
Get Rid of
Clot
http://www.daviddarling.info/images/
http://www.merckmanuals.com/media/home/figures/MMHE_14_173_01_eps.gif http://img.tfd.com/dorland/thumbs/
aneurysm_endovascular_stent.jpg

16. Transluminal
•Opens narrowed
tricuspid &
pulmonary valves or
veins
•series of inflation-
deflation cycles are
required to enlarge
"Percutaneous Transluminal Balloon Valvuloplasty." National Heart Centre
http://img.tfd.com/dorland/thumbs/angioplasty_balloon.jpg Singapore. N.p., 2010. Web. 20 Feb. 2011. <http://www.nhcs.com.sg/
patientcare/ConditionsAndTreatments/Pages/

17. Stents
•wire metal mesh
tube used to open
an artery
•reduces re-
narrowing which
occurs after
balloon procedure
"Stents." National Lung and Blood Institute . N.p., n.d. Web. 24
http://www.medgadget.com/archives/ Feb. 2011.
http://www.topnews.in/files/Medicated_Stents.2007.jpg
http://www.topnews.in/files/Medicated_Stents.2007.jpg http://www.medgadget.com/archives/img/Stent---side.jpg img/Stent---side.jpg <http://www.nhlbi.nih.gov/health/dci/Diseases/stents/

18. Testing:Activated Protein
C Resistance
•patient’s plasma is
diluted in Factor V-
deficient plasma; test is
done on that plasma
•result comes out as
Activated Protein C Resistance (APCR)." Florida
Hospital Center forThrombosis
Reasearch. N.p., 2008. Web. 27 Feb. 2011.
<http://www.fhthrombosis.com/APCR>.
http://www.factorvracing.com/wp-content/uploads/2011/02/Factor-V-Blood-Clot-Testing.jpg

19. APPOINTMENT

20. Treatm
http://www.about-alcoholism-facts.com/doctor-discussing-treatment-plan-with-chronic-alcoholic.jpg

21. http://www.pharmacyescrow.com/images/products/
265_LOVENOX-CLEXANE-ENOXAPARIN.gif

22. •
Injection
Loveno •helps reduce
risk of
developing
DVTs
•alters normal
clotting
What is Lovenox (enoxaparin)?" Greenwich Hospital (Sept.
2008): 2. PDF file.
http://3.bp.blogspot.com/_GsSpcCFkJdU/THw8xphCZtI/AAAAAAAABPA/VxbleyglVMU/s1600/75101154.caBX2gDb.syringe44671s.jpg

23. How does
•acts with antithrombin III which
neutralize activated Factor X
•inhibits the 2 clotting factors
Monson, Kristi, PharmD, and Arthur Schoenstadt, MD. "Lovenox." MedTV. N.p., 10
Aug. 2010. Web. 29 Mar. 2011. <http://blood.emedtv.com/lovenox/
http://www.freefoto.com/images/1216/05/1216_05_54---Stop-Sign--Beatty--Nevada--USA_web.jpg?&k=Stop
+Sign%2C+Beatty%2C+Nevada%2C+USA lovenox.html>.

24. How to
• standard spot to inject is abdomen;
“pinch an inch”
• if you must adjust dosage, put in
sink
• pinch skin and fat
• stick need in as far as it goes
• inject medication slowly
http://www.fulloma.com/wp-content/uploads/2008/10/needles.jpg Monson, Kristi, PharmD, and Arthur Schoenstadt, MD. "Lovenox." MedTV. N.p., 10

25. Side
Effect
s
"Lovenox." MY-VARICOSE-VEINS.COM. N.p., 2007. Web. 29 Mar. 2011.
<http://www.my-varicose-veins.com/lovenox.html>.

26. Side
Effect HIT itching
s
Platelet levels drop
ion
r itat
ir bruising
om a
redn ma t
he
ess
"Lovenox." MY-VARICOSE-VEINS.COM. N.p., 2007. Web. 29 Mar. 2011.
<http://www.my-varicose-veins.com/lovenox.html>.

28. Coumadin
•anticoagulant
medicine
•lowers chance of
blood clots
Coumadin. New Jersey: Bristol-
Myers Squibb, 2007. Print.
http://www.oralchelation.com/images/coumlogo.gif

29. Once on
• Get regular blood test
• eat a normal, balanced diet: no leafy
greens
• take at the same time every day
Coumadin. New Jersey: Bristol-
Myers Squibb, 2007. Print.
http://2.bp.blogspot.com/_4m3YdPyfLv8/SKr12hNfEpI/AAAAAAAAELw/BFMHzbbvNAU/s400/coumadin_pills.jpg

30. Monitor

31. How Does
Coumadin
• Liver makes
clotting
factors
• blocks
formation
of clotting
Coumadin. New Jersey: Bristol-Myers
Squibb, 2007. Print.
http://www.pharmaceutical-technology.com/projects/brecon-pharma/images/4-
pills-and-capsules.jpg

32. Side
http://www.funnypostcard.com/images/side-effects.jpg

33. Application #1
•T-Shirts

34. t-shirts
• pictures

35. Application #2-
Raise
d

36. Bake Sale 2
• pictures

37. Dona
Thrombop
hilia
Awareness
Project
http://www.fvleiden.org/images/tap_logo2.gif

38. PL
Class Activity EA
E D CA BE SE
R V RE
R O FU
E R :) L
http://static.ragamuffinsoul.com/wp-content/uploads/2008/04/rr.jpg

39. • http://www.bmj.com/content/313/7065/1127/F1.large.jpg
Works
http://spl225.files.wordpress.com/2009/12/dictionary11.jpg
Definition of Thrombosis." MedicineNet. MedicineNet, Inc, 1996. Web. 27 Feb.
2011. <http://www.medterms.com/script/main/art.asp?articlekey=25023
http://trendsupdates.com/key-molecular-mechanism-of-blood-clotting-discovered/
http://thinkexist.com/quotes/with/keyword/blood/
http://www.buddhistchannel.tv/picture/upload/buddha-leafs.jpg
http://www.ancientsculpturegallery.com/images/2982.jpg
http://raisingrrl.files.wordpress.com/2009/02/o005-buddha-w-beads-jade.jpg
http://topnews.com.sg/images/genes.jpg
Hamilton Health Science (Aug. 2007). PDF file.
"Heterozygous Factor V Leiden." Chart. Hamilton Health Sciences. N.p., 17 Aug.
2007. Web. 17 Feb. 2011. <http://www.stoptheclot.org/documents/
FactorVLeiden-lw.pdf>.
"Homozygous Factor V Leiden." Chart. Hamilton Health Sciences. N.p., 17 Aug.
2007. Web. 17 Feb. 2011.
http://www.merckmanuals.com/media/home/figures/MMHE_14_173_01_eps.gif
http://img.tfd.com/dorland/thumbs/angioplasty_balloon.jpg
http://www.daviddarling.info/images/aneurysm_endovascular_stent.jpg
http://img.tfd.com/dorland/thumbs/angioplasty_balloon.jpg
"Percutaneous Transluminal Balloon Valvuloplasty." National Heart Centre
Singapore. N.p., 2010. Web. 20 Feb. 2011. <http://www.nhcs.com.sg/
patientcare/ConditionsAndTreatments/Pages/
PercutaneousBalloonValvuloplasty.aspx
http://www.topnews.in/files/Medicated_Stents.2007.jpg
http://www.topnews.in/files/Medicated_Stents.2007.jpg
http://www.medgadget.com/archives/img/Stent---side.jpg
http://www.medgadget.com/archives/img/Stent---side.jpg
"Stents." National Lung and Blood Institute . N.p., n.d. Web. 24 Feb. 2011.
<http://www.nhlbi.nih.gov/health/dci/Diseases/stents/stents_used.html>.
Activated Protein C Resistance (APCR)." Florida Hospital Center forThrombosis
Reasearch. N.p., 2008. Web. 27 Feb. 2011.
<http://www.fhthrombosis.com/APCR>.
http://www.factorvracing.com/wp-content/uploads/2011/02/Factor-V-Blood-Clot-Testing.jpg
http://www.about-alcoholism-facts.com/doctor-discussing-treatment-plan-with-chronic-alcoholic.jpg
http://www.pharmacyescrow.com/images/products/265_LOVENOX-CLEXANE-ENOXAPARIN.gif
What is Lovenox (enoxaparin)?" Greenwich Hospital (Sept. 2008): 2. PDF file.
http://3.bp.blogspot.com/_GsSpcCFkJdU/THw8xphCZtI/AAAAAAAABPA/VxbleyglVMU/s1600/75101154.caBX2gDb.syringe44671s.jpg
http://www.freefoto.com/images/1216/05/1216_05_54---Stop-Sign--Beatty--Nevada--USA_web.jpg?&k=Stop+Sign%2C+Beatty%2C+Nevada%2C+USA
http://www.fulloma.com/wp-content/uploads/2008/10/needles.jpg
Coumadin. New Jersey: Bristol-Myers Squibb, 2007. Print.
http://www.oralchelation.com/images/coumlogo.gif
Coumadin. New Jersey: Bristol-Myers Squibb, 2007. Print.
http://2.bp.blogspot.com/_4m3YdPyfLv8/SKr12hNfEpI/AAAAAAAAELw/BFMHzbbvNAU/s400/coumadin_pills.jpg
Coumadin. New Jersey: Bristol-Myers Squibb, 2007. Print.
http://www.pharmaceutical-technology.com/projects/brecon-pharma/images/4-pills-and-capsules.jpg
DVT & Pulmonary Embolism. Prevent DVT. Web. 29 Mar. 2011.
<http://www.preventdvt.org/media/dvt-videos/glassman.aspx>.
Monson, Kristi, PharmD, and Arthur Schoenstadt, MD. "Lovenox." MedTV. N.p., 10
Aug. 2010. Web. 29 Mar. 2011. <http://blood.emedtv.com/lovenox/
lovenox.html>.
"Lovenox." MY-VARICOSE-VEINS.COM. N.p., 2007. Web. 29 Mar. 2011.
<http://www.my-varicose-veins.com/lovenox.html>.
Monson, Kristi, PharmD, and Arthur Schoenstadt, MD. "Lovenox." MedTV. N.p., 10
Aug. 2010. Web. 29 Mar. 2011. <http://blood.emedtv.com/lovenox/how-to-give-lovenox-injections-p2.html>
http://www.funnypostcard.com/images/side-effects.jpg
Blood Clot Video. HealthLine. Web. 30 Mar. 2011. <http://www.healthline.com/
vpvideo/blood-clot>.

40. In Conclusion
•
In conclusion,