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Chapter 1 
Nursing Management of Drug 
Therapy 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins 
Question 
• ______________ are the changes that occur to the drug 
while it is inside the body. 
– A. Pharmacotherapeutics 
– B. Pharmacokinetics 
– C. Pharmacodynamics
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins 
Answer 
• B. Pharmacokinetics 
• Rationale: Pharmacokinetics are the changes that 
occur to the drug while in the body.
Core Drug Knowledge 
• Pharmacotherapeutics: the desired, therapeutic effect 
of the drug 
· Pharmacokinetics: the changes that occur to the drug 
while it is inside the body 
· Pharmacodynamics: the effects of the drug on the 
body 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Core Drug Knowledge (cont.) 
· Contraindications and precautions: the conditions 
under which the drug should not be used or must be 
used carefully with monitoring 
· Adverse effects: the unintended and usually undesired 
effects that may occur with the use of the drug 
· Drug interactions: the effects that may occur when the 
drug is given along with another drug, food, or substance 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Core Patient Variables 
• Health status: overall health of the patient 
• Life span and gender: age and gender 
• Lifestyle, diet, and habits: occupation, finances, 
substance use, exercise 
• Environment: where will the drug be administered 
• Culture and inherited traits: cultural beliefs 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Nursing Management of Drug Therapy 
• Maximize the therapeutic effects of a drug 
• Minimize the adverse effects of a drug 
• Provide patient and family education 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Management of Drug Therapies 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Health Care Settings 
• Hospitals 
• Long-term care facilities 
• Outpatient centers and clinics 
• Health care providers’ offices 
• Patients’ homes 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Managing Drug Therapy Using the Nursing 
Process 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins 
Question 
• What percentage of the population in the United States 
takes at least one medication in a month? 
– A. 10% 
– B. 25% 
– C. 33% 
– D. 45%
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins 
Answer 
• D. 45% 
• Rationale: In any given month, almost 45% of the 
U.S. population will receive one prescription drug. 
This percentage is higher in the aging population.
Drug Usage in the United States 
• Approximately 45% of the population receives one drug 
in any given month. 
• Prescription drug use increases with each age group. 
• Approximately 85% of adults aged 65 and older are 
receiving one prescription per month. 
• Almost 50% of adults aged 65 and older are receiving 
three or more prescriptions a month. 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Assessment: Core Drug Knowledge 
• Current medications a patient is taking 
• Interaction between medications 
• Use of resources to identify drugs that are unfamiliar 
• Use of prototype drugs to increase understanding of 
different medications 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Prototype Drug 
• Typical of a medication within a drug class 
• Typically the first drug of a class 
• Drug has similar characteristics to all drugs in a class of 
drugs 
• Provides a systematic way to increase knowledge of 
medications 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Three Sources of Assessment Data 
• The patient interview and history 
• The physical examination 
• The medical record 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Patient Interview and History 
• Health status 
– Assess functioning of body systems and organs 
• Life span and gender 
– Needed to plan patient education on drug therapy 
• Lifestyle, diet, and habits 
– Can cause potential effect on drug therapy 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Patient Interview and History (cont.) 
• Environment 
– The patient’s adherence to the drug regimen 
– Potential risks from the therapy where the drug will 
be administered 
• Culture and inherited traits 
– Affect the patient’s acceptance of prescribed drug 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins 
therapy
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins 
Question 
• Objective data are the data collected from the patient’s 
story. 
– A. True 
– B. False
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins 
Answer 
• B. False 
• Rationale: Subjective data are what the patient tells 
the nurse; objective data are the data the nurse 
collects by completing a physical examination of the 
patient.
Physical Examination 
• Focus on health status, life span, and gender 
• Comprehensive 
• Physical assessment of each body system 
• Vital signs 
• Height and weight 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Medical Record 
• The medical record provides information about the 
patient’s health status, lifestyle, diet, habits, and 
environment. 
• Laboratory test and diagnostic test results 
• Drug history 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Purpose of Data Collection 
• Interpretation of data based on their relevance to drug 
therapy 
• The nurse uses the drug knowledge and patient variables 
to determine any significant drug interactions. 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Nursing Diagnosis 
• North America Nursing Diagnosis Association (NANDA) 
• Reflect a current, actual problem or the risk for 
developing a problem related to drug therapy 
• Diagnoses may reflect effects of drugs. 
• Nursing diagnoses are highly individualized. 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Nursing Outcomes 
• Outcomes determine the desired results. 
• Outcomes are based on data collected. 
• Outcomes are specific to the patient’s drug regimen. 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Maximizing Therapeutic Effects 
• Administer the drug in a manner that will promote its 
absorption 
• Administer the drug at the appropriate time 
• Monitor laboratory values 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Minimizing Adverse Effects 
• Verify the patient’s allergies 
• Assess for contraindication for the drug therapy 
• Administer the drug in a manner consistent with standard 
safety protocols 
• Monitor the patient and relevant laboratory findings 
• Discontinue or withhold a drug based on assessment or 
laboratory findings 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Minimizing Adverse Effects (cont.) 
• Report evidence of adverse effects to the prescriber 
• Modify administration techniques, when appropriate 
• Implement appropriate assessment for certain drugs to 
detect the onset of adverse effects 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Core Drug Knowledge 
• Understand the drug’s response 
• Basics of teaching patient and family about drug therapy 
– Name of the drug 
– Reason the drug was prescribed 
(pharmacotherapeutics) 
– Intended effect of the drug (pharmacodynamics) 
– Important adverse effects that may occur 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Core Patient Variables 
• Health status 
– Activities that must be performed while the patient 
receives the drug 
• Life span and gender 
– Adverse effects on a developing fetus 
– Used for patient education 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
Core Patient Variables (cont.) 
• Lifestyle, diet, and habits 
– Changes the patient may need to make during drug 
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins 
therapy 
• Environment 
– To promote effective self-managed drug therapy 
• Culture and inherited traits 
– Consider cultural issues and modify content or 
presentation accordingly
Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins 
Evaluation 
• Measures the patient’s progress 
• Consider whether the drug achieved the desired effect 
• Outcomes that are not achieved 
– Reassess to identify barriers to success 
• Must identify the reason behind any treatment failure

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Ppt chapter 01-1

  • 1. Chapter 1 Nursing Management of Drug Therapy Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 2. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Question • ______________ are the changes that occur to the drug while it is inside the body. – A. Pharmacotherapeutics – B. Pharmacokinetics – C. Pharmacodynamics
  • 3. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Answer • B. Pharmacokinetics • Rationale: Pharmacokinetics are the changes that occur to the drug while in the body.
  • 4. Core Drug Knowledge • Pharmacotherapeutics: the desired, therapeutic effect of the drug · Pharmacokinetics: the changes that occur to the drug while it is inside the body · Pharmacodynamics: the effects of the drug on the body Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 5. Core Drug Knowledge (cont.) · Contraindications and precautions: the conditions under which the drug should not be used or must be used carefully with monitoring · Adverse effects: the unintended and usually undesired effects that may occur with the use of the drug · Drug interactions: the effects that may occur when the drug is given along with another drug, food, or substance Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 6. Core Patient Variables • Health status: overall health of the patient • Life span and gender: age and gender • Lifestyle, diet, and habits: occupation, finances, substance use, exercise • Environment: where will the drug be administered • Culture and inherited traits: cultural beliefs Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 7. Nursing Management of Drug Therapy • Maximize the therapeutic effects of a drug • Minimize the adverse effects of a drug • Provide patient and family education Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 8. Management of Drug Therapies Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 9. Health Care Settings • Hospitals • Long-term care facilities • Outpatient centers and clinics • Health care providers’ offices • Patients’ homes Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 10. Managing Drug Therapy Using the Nursing Process Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 11. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Question • What percentage of the population in the United States takes at least one medication in a month? – A. 10% – B. 25% – C. 33% – D. 45%
  • 12. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Answer • D. 45% • Rationale: In any given month, almost 45% of the U.S. population will receive one prescription drug. This percentage is higher in the aging population.
  • 13. Drug Usage in the United States • Approximately 45% of the population receives one drug in any given month. • Prescription drug use increases with each age group. • Approximately 85% of adults aged 65 and older are receiving one prescription per month. • Almost 50% of adults aged 65 and older are receiving three or more prescriptions a month. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 14. Assessment: Core Drug Knowledge • Current medications a patient is taking • Interaction between medications • Use of resources to identify drugs that are unfamiliar • Use of prototype drugs to increase understanding of different medications Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 15. Prototype Drug • Typical of a medication within a drug class • Typically the first drug of a class • Drug has similar characteristics to all drugs in a class of drugs • Provides a systematic way to increase knowledge of medications Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 16. Three Sources of Assessment Data • The patient interview and history • The physical examination • The medical record Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 17. Patient Interview and History • Health status – Assess functioning of body systems and organs • Life span and gender – Needed to plan patient education on drug therapy • Lifestyle, diet, and habits – Can cause potential effect on drug therapy Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 18. Patient Interview and History (cont.) • Environment – The patient’s adherence to the drug regimen – Potential risks from the therapy where the drug will be administered • Culture and inherited traits – Affect the patient’s acceptance of prescribed drug Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins therapy
  • 19. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Question • Objective data are the data collected from the patient’s story. – A. True – B. False
  • 20. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Answer • B. False • Rationale: Subjective data are what the patient tells the nurse; objective data are the data the nurse collects by completing a physical examination of the patient.
  • 21. Physical Examination • Focus on health status, life span, and gender • Comprehensive • Physical assessment of each body system • Vital signs • Height and weight Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 22. Medical Record • The medical record provides information about the patient’s health status, lifestyle, diet, habits, and environment. • Laboratory test and diagnostic test results • Drug history Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 23. Purpose of Data Collection • Interpretation of data based on their relevance to drug therapy • The nurse uses the drug knowledge and patient variables to determine any significant drug interactions. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 24. Nursing Diagnosis • North America Nursing Diagnosis Association (NANDA) • Reflect a current, actual problem or the risk for developing a problem related to drug therapy • Diagnoses may reflect effects of drugs. • Nursing diagnoses are highly individualized. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 25. Nursing Outcomes • Outcomes determine the desired results. • Outcomes are based on data collected. • Outcomes are specific to the patient’s drug regimen. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 26. Maximizing Therapeutic Effects • Administer the drug in a manner that will promote its absorption • Administer the drug at the appropriate time • Monitor laboratory values Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 27. Minimizing Adverse Effects • Verify the patient’s allergies • Assess for contraindication for the drug therapy • Administer the drug in a manner consistent with standard safety protocols • Monitor the patient and relevant laboratory findings • Discontinue or withhold a drug based on assessment or laboratory findings Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 28. Minimizing Adverse Effects (cont.) • Report evidence of adverse effects to the prescriber • Modify administration techniques, when appropriate • Implement appropriate assessment for certain drugs to detect the onset of adverse effects Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 29. Core Drug Knowledge • Understand the drug’s response • Basics of teaching patient and family about drug therapy – Name of the drug – Reason the drug was prescribed (pharmacotherapeutics) – Intended effect of the drug (pharmacodynamics) – Important adverse effects that may occur Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 30. Core Patient Variables • Health status – Activities that must be performed while the patient receives the drug • Life span and gender – Adverse effects on a developing fetus – Used for patient education Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
  • 31. Core Patient Variables (cont.) • Lifestyle, diet, and habits – Changes the patient may need to make during drug Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins therapy • Environment – To promote effective self-managed drug therapy • Culture and inherited traits – Consider cultural issues and modify content or presentation accordingly
  • 32. Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins Evaluation • Measures the patient’s progress • Consider whether the drug achieved the desired effect • Outcomes that are not achieved – Reassess to identify barriers to success • Must identify the reason behind any treatment failure