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TUESDAY GRAND ROUND
CASE PRESENTATION
Ahmed Alkhazndar
Ahmed abdelnaser
13/ 6/ 2023
AL-AZHAR UNIVERSITY
Faculty of Medicine
Neurology Department
PERSONAL HISTORY
• A 71 years old male patient retired policeman Rt handed
COMPLAINT
• Weakness of both lower limbs 3 months duration
HISTORY OF PRESENT ILLNESS
• The condition has started 3 month ago by gradual onset progressive
course when the patient developed lower back pain which was localized
, throbbing (some times stabbing )moderate to sever ,increased with
cough ,sneezing and movement and became more sever at night ,
decreased slightly with rest and analgesia , radiating to both buttocks
• 1month later patient developed weakness in both lower limbs which was
left more than right , proximal more than distal , flexor equal extensor
associated with hypotonia completed within 1 month till patient became
wheelchair
1.5 month from the onset of the condition the relevant noticed wasting
in both lower limbs especially the anterior aspect of the thigh
Patient also noticed worm like sensation at the anterior part of the thigh
at the beginning of weakness then disappeared nowadays
At the beginning of the weakness the patient has complained from
urine incontinence and lately became complaining from urine and stool
incontinence
• 3 weeks ago patient has complained from mid- dorsal localized pain
(carry the same character of lower back pain ) without increasing in
the previous weakness .
during period of the disease
Patient denied any associated fever or
significant weight loss all over the course of
disease
No history suggestive upper limbs affection
No history suggestive cranial nerve affection
No history suggestive cerebellar affection
No history suggestive trauma ,headache or
fits
No history of raw milk ingestion or contact to
animal
• Born and live in Giza
• Married
• Has 3 sibling the youngest is 29 y .o
• Smoker
• No other special habit of medical important
• Social history
PAST HISTORY
Diabetes uncontrolled for 25 year on oral treatment
Hypertensive
left head femur fraction (nail and screw fixation) 2 years ago
No history of blood transfusion
No history of trauma
No history of liver or kidney disease
No history of drug addiction .
• Irrelevant
• Family history
FORMULATION
Male patient 71 year old diabetic uncontrolled and
hypertensive presented 3 months ago by gradual
onset progressive course of :
 Lower back bony pain
Asymmetrical lower motor neuron weakness in both
lower limbs
 urine and stool incontinence
Mid dorsal bony pain
GENERAL EXAMINATION
• BP: 110/70
• Pulse: 84 beats/m, regular, average volume, equal on both sides.
• RR: 14 cycle/m.
• T: 37◦ C.
• Head and Neck: no characteristic facies, normal thyroid.
• Chest: fair air entry, no adventitious sounds.
• Heart: normal S1 & S2, no murmurs, gallops or rub.
• Abdomen: Lax abdomen, not tender, no detectable ascits or supra
pubic dullness.
• Skin : no rash, plaques only atrophic changes in both feet
NEUROLOGICAL EXAMINATION
MENTAL STATE
• The patient is fully conscious, attentive, well oriented to time, place,
person, with intact memory, depressed mood .
• MMSE : 25/30
SPEECH
• No dysarthria or aphasia
CRANIAL NERVES
• Olfactory: intact
• Optic:
 VA: Rt: 6/6; Lt: 6/6.
 Color vision: intact
 Visual field: NAD
 Fundus examination: diabetic retinopathy
• Occulomotor, Trochlear, Abducens:
 Intact ocular motility
 Pupil : RRR bilateral; Light reflex: intact both direct and indirect
CRANIAL NERVES
• Trigeminal :
 Intact motor and sensory examination.
 Corneal reflex: intact
 Jaw reflex: just elicited
• Facial Nerve:
 No facial asymmetry
 Glabellar reflex: normal
• Vestibulo-Cochlear:
 Cochlear part: Intact
 Vestibular part: intact .
CRANIAL NERVES
• Glossopharyngeal, Vagus:
 Uvula: Centralized
 Palatal movement: Intact on both side
 Palatal& Pharyngeal Reflexes: present bilaterally
• Hypoglossal Nerve:
 Tongue: no wasting, abnormal movements or fasciculation.
MOTOR SYSTEM
Upper limbs :
Muscle state ,wasting and guttering in the small muscle of the hands
Power : full power
Reflexes;normal reflexes
Lower limbs
Inspection ; wasting in the medial and
anterior side of the thigh and anterior aspect
of the leg
Power ; left more than right proximal more
than distal , adduction more than abduction
, extensors more than flexors
left lower limb
Hipe flexion G2
Hipe extention G3
HIPE abducition G-4
HIPE adduction G 2
Knee flexor G2
Knee extensor G3
Ankle dorsiflexion
G3
Planter flexion G4
Right lower limbe
Hipe flexion g3
HIPE EXTENTION G-4
HIPE ABDUCTION G4
HIPE ADDUCTION G3
KNEE FLEXOR G3
KNEE EXTENSORE G4
PLUNTER EXTENSOR G-4
PLUNTER FLEXOR +4
Motor of the lower limbe
REFLEXES
• Deep tendon reflexes:
• Areflexia of both ankle
• Areflexia of both knee
• Normal biceps, brachioradialis and triceps
• Superficial reflexes
 Abdominal: INTACT (upper, middle, lower)
 Plantar: Bilateral flexor planter reflex.
2+
0
0 0
2+ 2+
2+
2+
2+
0
SENSORY SYSTEM
• Superficial: glove and HIGH stock hypothesia
• Hypothesia at saddle area
• Deep: VIBRATION SENSATION LOST ON MEDIAL MALLEOLUS and
preserved at tibial tuobersty
CEREBELLUM
 No truncal ataxia.
 no ataxia on doing :
Finger to nose, finger to finger.
BACK
• No Scoliosis or kyphosis.
• No skin pigmentation.
• localized tenderness at mid dorsal and lower back
OTHER
• positive stretch signs
• No suprabupic dullness
LABORATORY TESTS
• AST = 29 U/l
• ALT = 31 U/l
• Creatinine = 1.3 mg/dl
• Urea = 40
• ESR = 55 (1st hour).
• Hb = 11 g/dl
• TLC = 7.9 k/ul
• Crp= 116
IMAGING

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DOC-20230904-WA0007..pptx

  • 1. TUESDAY GRAND ROUND CASE PRESENTATION Ahmed Alkhazndar Ahmed abdelnaser 13/ 6/ 2023 AL-AZHAR UNIVERSITY Faculty of Medicine Neurology Department
  • 2. PERSONAL HISTORY • A 71 years old male patient retired policeman Rt handed
  • 3. COMPLAINT • Weakness of both lower limbs 3 months duration
  • 4. HISTORY OF PRESENT ILLNESS • The condition has started 3 month ago by gradual onset progressive course when the patient developed lower back pain which was localized , throbbing (some times stabbing )moderate to sever ,increased with cough ,sneezing and movement and became more sever at night , decreased slightly with rest and analgesia , radiating to both buttocks • 1month later patient developed weakness in both lower limbs which was left more than right , proximal more than distal , flexor equal extensor associated with hypotonia completed within 1 month till patient became wheelchair
  • 5. 1.5 month from the onset of the condition the relevant noticed wasting in both lower limbs especially the anterior aspect of the thigh Patient also noticed worm like sensation at the anterior part of the thigh at the beginning of weakness then disappeared nowadays At the beginning of the weakness the patient has complained from urine incontinence and lately became complaining from urine and stool incontinence
  • 6. • 3 weeks ago patient has complained from mid- dorsal localized pain (carry the same character of lower back pain ) without increasing in the previous weakness .
  • 7. during period of the disease Patient denied any associated fever or significant weight loss all over the course of disease No history suggestive upper limbs affection No history suggestive cranial nerve affection No history suggestive cerebellar affection No history suggestive trauma ,headache or fits No history of raw milk ingestion or contact to animal
  • 8. • Born and live in Giza • Married • Has 3 sibling the youngest is 29 y .o • Smoker • No other special habit of medical important • Social history
  • 9. PAST HISTORY Diabetes uncontrolled for 25 year on oral treatment Hypertensive left head femur fraction (nail and screw fixation) 2 years ago No history of blood transfusion No history of trauma No history of liver or kidney disease No history of drug addiction .
  • 11. FORMULATION Male patient 71 year old diabetic uncontrolled and hypertensive presented 3 months ago by gradual onset progressive course of :  Lower back bony pain Asymmetrical lower motor neuron weakness in both lower limbs  urine and stool incontinence Mid dorsal bony pain
  • 13. • BP: 110/70 • Pulse: 84 beats/m, regular, average volume, equal on both sides. • RR: 14 cycle/m. • T: 37◦ C.
  • 14. • Head and Neck: no characteristic facies, normal thyroid. • Chest: fair air entry, no adventitious sounds. • Heart: normal S1 & S2, no murmurs, gallops or rub. • Abdomen: Lax abdomen, not tender, no detectable ascits or supra pubic dullness. • Skin : no rash, plaques only atrophic changes in both feet
  • 16. MENTAL STATE • The patient is fully conscious, attentive, well oriented to time, place, person, with intact memory, depressed mood . • MMSE : 25/30
  • 18. CRANIAL NERVES • Olfactory: intact • Optic:  VA: Rt: 6/6; Lt: 6/6.  Color vision: intact  Visual field: NAD  Fundus examination: diabetic retinopathy • Occulomotor, Trochlear, Abducens:  Intact ocular motility  Pupil : RRR bilateral; Light reflex: intact both direct and indirect
  • 19. CRANIAL NERVES • Trigeminal :  Intact motor and sensory examination.  Corneal reflex: intact  Jaw reflex: just elicited • Facial Nerve:  No facial asymmetry  Glabellar reflex: normal • Vestibulo-Cochlear:  Cochlear part: Intact  Vestibular part: intact .
  • 20. CRANIAL NERVES • Glossopharyngeal, Vagus:  Uvula: Centralized  Palatal movement: Intact on both side  Palatal& Pharyngeal Reflexes: present bilaterally • Hypoglossal Nerve:  Tongue: no wasting, abnormal movements or fasciculation.
  • 21. MOTOR SYSTEM Upper limbs : Muscle state ,wasting and guttering in the small muscle of the hands Power : full power Reflexes;normal reflexes
  • 22. Lower limbs Inspection ; wasting in the medial and anterior side of the thigh and anterior aspect of the leg Power ; left more than right proximal more than distal , adduction more than abduction , extensors more than flexors
  • 23. left lower limb Hipe flexion G2 Hipe extention G3 HIPE abducition G-4 HIPE adduction G 2 Knee flexor G2 Knee extensor G3 Ankle dorsiflexion G3 Planter flexion G4 Right lower limbe Hipe flexion g3 HIPE EXTENTION G-4 HIPE ABDUCTION G4 HIPE ADDUCTION G3 KNEE FLEXOR G3 KNEE EXTENSORE G4 PLUNTER EXTENSOR G-4 PLUNTER FLEXOR +4 Motor of the lower limbe
  • 24. REFLEXES • Deep tendon reflexes: • Areflexia of both ankle • Areflexia of both knee • Normal biceps, brachioradialis and triceps • Superficial reflexes  Abdominal: INTACT (upper, middle, lower)  Plantar: Bilateral flexor planter reflex. 2+ 0 0 0 2+ 2+ 2+ 2+ 2+ 0
  • 25. SENSORY SYSTEM • Superficial: glove and HIGH stock hypothesia • Hypothesia at saddle area • Deep: VIBRATION SENSATION LOST ON MEDIAL MALLEOLUS and preserved at tibial tuobersty
  • 26. CEREBELLUM  No truncal ataxia.  no ataxia on doing : Finger to nose, finger to finger.
  • 27. BACK • No Scoliosis or kyphosis. • No skin pigmentation. • localized tenderness at mid dorsal and lower back
  • 28. OTHER • positive stretch signs • No suprabupic dullness
  • 29. LABORATORY TESTS • AST = 29 U/l • ALT = 31 U/l • Creatinine = 1.3 mg/dl • Urea = 40 • ESR = 55 (1st hour). • Hb = 11 g/dl • TLC = 7.9 k/ul • Crp= 116