2. • Do we know all the anatomical structures of the brain?
• How many cells are there?
• How much of our brain can we use?
• What are all the functions of the brain?
• Eloquent areas?
• What`s inside a woman`s brain?
• Does Brain Size matter?
• Brain disorders
• Is brain recovery possible?
• Neuroregeneration?
• Is the improvement of brain function possible?
• Do we have a brain cell panacea?
IMPORTANT BRAIN QUESTIONS :
Brain Health Formula ??
3. Summary
• Human Brain General Data
• Human Brain Function
• Dangers for Human Brain
• Brain Recovery
• GNC Products
• Conclusions + Q & A
5. Every day of our life we burn up 1 neuron/second (normal
conditions)
We should live up to 300 years
(Prof. Dr. L. Zagrean – Carol Davila University – Chair
of Physiology and neurosciences)
Hundreds of trillions of neural pathways
Like a „Choose your adventure book” from here to Jupiter.
BRAIN FACTS
6. Unipolar Neurons
Multipolars Neurons:
n. dendritis – receive information
one axon – transmission information
Synaptic connections
CNS to CNS
CNS to endocrine
CNS to blood
CNS to organism
BRAIN FACTS
TRANSMISSIONS
7. ALL LITERATURE DATA SHOWS THAT THE NUMBER OF SYNAPSES
IS PROPORTIONAL WITH THE ACTIVITY OF THE BRAIN
How a synapse loos like
Links: synaptic connections 6x1018 - 24x1019 Synapses
(Harvard brain facts)
Ciurea et al., 2016
14. BRAIN AND EDUCATION
First 6 mth 80%
Next 6 mth 50%
Next 6 mth 30%
2 y 30%
3 y 20%
4 y 15%
At birth = 365g/3.50 Kg
At adulthood = 1600g/80 Kg
Young brain is prone
to learning
Difference = ?
Water,
Myelin,
Glial cells,
Synapses;
15. •Some studies argue that we use 10-15% of our brain.
•Judging by how we think….It should look like
this….
True or false ?
Argument :
•Ahad Israfil is a gunshot victim from Dayton, Ohio, remarkable for his
recovery from an injury that destroyed most or all of one cerebral
hemisphere.
•He is perfectly functional without 50% of his brain !
HOW MUCH OF OUR BRAIN DOWE USE ?
16. Geniality areas
Brain areas involved in metaphorical and
abstract thinking.
Corpus callosum development
Angular gyrus (left side)
HUMAN BRAIN ANATOMY- HIDDEN AREA
17. IQ AND BRAIN
IQ is related with:
Normal neurological function
Appropriate cerebral vascular perfusion
No traumatic injuries
Many synapses
Many connections
18. Summary
• Human Brain General Data
• Human Brain Function
• Dangers for Human Brain
• Brain Recovery
• GNC Products
• Conclusions + Q & A
21. BRAIN & STRESS
Family Psychical conflicts
1. Numerous cellular signaling
pathways and wearing neurons out.
2. Triggers oxidative stress, a possible
generator of Alzheimer’s
23. Psychic conflicts
•Arguments are a major cause of neuron
apoptosis
•Great amounts of stress are being generated
that afect the whole body system.
•Tremendous amounts of neuromediators are
generated triggering numerous cellular
signaling pathways and wearing neurons out.
•Triggers oxidative stress, a possible generator
of Alzheimer’s
Brain & Stress
24.
25. Polluted air, fumes, gases, benzene, CO, CO2, etc
BRAIN & ENVIROMENT
Beijing
Paris
Tokio
Brain lacks oxygen
35. Akhlaq A. Farooqui
Department of Molecular and Cellular Biochemistry
The Ohio State University Columbus, OH 43221, USA
• Fish oil promotes neuronal
differentiation
• More branches, longer neurites
• Fish oil improves the surgical
outcome of patients.
FISH OIL
BRAIN & FOOD
36. Summary
• Human Brain General Data
• Human Brain Function
• Dangers for Human Brain
• Brain recovery
• GNC Products
• Conclusions + Q & A
38. BRAIN AND NEURORECOVERY
Targets the neurometabolic pathways
Lead to the development of new neuronal
interconnections
Lead to the development of new networked activities
Optimize the brain vascular irigation (CPP)
Development of new neurorehabilitation therapies
Blood
Oxygen & Glucose
The fuel of life
39. Actual theories:
Neuroregeneration
Where? In hippocampal area
How many? 500 / day
Stimulating factors: physical activity, sleeping / rest, fresh
air, optimistic / positive thoughts, clean water and healthy food
Inhibitors: obesity, inactivity, depression, depression,
DEPRESSION, alcohol consumption, smoking…
Ciurea et al., 2016
BRAIN AND NEURORECOVERY
40. 1. Neuroprotective therapies:
- Stimulate neuro-metabolism
2. New neuronal interconnection
- Development new network
activities
3. Brain vascular irrigation (CPP)
4. Neurorehabilitation therapies
BRAIN NEURORECOVERY
41. VEGETABLES AND FRUITS
•The most important part of a diet.
•Contain high levels of vitamins, proteins and
microelements involved in all the mechanisms of the body.
BRAIN RECOMMENDATIONS I
42. VEGETABLES AND FRUITS
• Garlic, Basil, Parsley have highly speculated anti-
carcinogenic effects
•High levels of anti-oxidants and chlorophile
BRAIN RECOMMENDATIONS II
43. BRAIN RECOMMENDATIONS III
VITAMINE E
• Almonds
• Crude seeds
• Mangold
• Pine Buds
• Spinach
• Broccoli
• Kale leafs
• Avocado
• Papaya
• Olive
• Parsley
↓↓↓ oxidative stress
44. CHOCOLATE
COFFEE AND COCOA
VIP EFFECTS
• High levels of Iron
• High levels of glucose (caution)
• High levels of phosphatidyl coline
• High levels of natural antioxidants
BRAIN RECOMMENDATIONS IV
45. BRAIN RECOMMENDATIONS V
Mandatory rest and sleep!
Inflammatory
reactions
Amyloid
plaques
accumulation
Overly
stimulated
microglia
Synaptic and
neural
damage
FASTER
EVOLUTION
OF
ALZHEIMER
DISEASE
Deep slow wave sleep reduces amyloid plaques.
David M. Holtzman et al. Slow
wave sleep disruption increases
cerebrospinal fluid amyloid-β
levels. Brain, July 2018
↑ Deep slow
wave sleep
↑ microglia mecanism of
”cleaning” the
accumulation of amyloid
46. 1. Neuroprotective therapies:
- Stimulate neuro-metabolism
2. New neuronal interconnection
- Development new network activities
3. Brain vascular irrigation (CPP)
4. Neurorehabilitation therapies
BRAIN NEURORECOVERY
47. Summary
• Human Brain General Data
• Human Brain Function
• Dangers for Human Brain
• GNC Products for brain
• Conclusions + Q & A
49. Brain Health Formula
Compozitie / 2 capsule Cantitate
Vitamina C (acid ascorbic) 50 mg
Vitamina D-3 (colecalciferol)
5 mcg
(200 UI)
Vitamina B-6 (clorhidrat de piridoxina si 5-fosfat-piridoxal)
50 mg
Folat (5-metiltetrahidrofolat)
166 mcg DFE
(100 mcg acid folic)
Vitamina B-12 (cianocobalamina) 100 mcg
Colina (bitartrat de colina) 100 mg
Amestec pentru suportul activitatii cerebrale 710.1 mg
L-tirozina 500 mg
Acetil L-carnitina (clorhidrat de acetil L-carnitina) 100 mg
Fosfatidilserina 100 mg
DMAE (2-(dimetilamino) etanol) 10 mg
Huperzina A 100 mcg
Complex pentru suportul circulatiei & fluxului sanguin 201 mg
Extract din frunze de Gingko Biloba (24% flavonglicozide din Gingko
28.8 mg, 6% lactone terpenice 7.2 mg)
120 mg
Extract din radacina de Turmeric (Curcuma longa) (Curcumina 20%
= 10 mg)
50 mg
resVida® trans-Resveratrol 30 mg
Astaxantina 1 mg
Amestesc suport antioxidant 180 mg
Extract din frunze de Bacopa Monnieri 100 mg
Extract din radacina de Ashwagandha (Withania somnifera) 50 mg
Pulbere din radacina de ghimbir (Zingiber officinalis) 23 mg
Lutemax® 2000 Luteina 7 mg
Mod de administrare:2 tablete,
in timpul mesei.
50. Coline
Psychostimulant
Intermediate product in intracellular production of
phosphatidylcholine from choline (required for correct cell
membrane functioning)
GNC- Brain Health Formula
Composition
51. Contains ingredients that are part of the
cerebral structure and easily cross the
blood-brain barrier;
act synergistically;
have increased bioavailability;
GNC- Brain Health Formula
Composition
52. Improved formula with:
Phosphatidylserine,
L-Tyrosine,
Resvida-trans-Resveratrol,
Acetyl L-carnitine
2 –dimetilamino (etanol)
Curcumin
Huperzina A
GNC- Brain Health Formula
Composition
53. GNC- Brain Health Formula
Efect I
• Maintaining the structure, permeability and fluidity of
neural cell membranes
• Helps improve the synthesis of phosphatidylcholine, a
major component of gray matter;
• Maintaining osmotic balance;
• Increasing the level of energy in nerve cell mitochondria
(ATP): helps to facilitate the metabolism of fatty acids, to
increase cerebral glucose;
56. Reducing neurotoxicity given by excess of:
o glutamate (excitatory neurohormone),
o lipofuscin (a non-demineralized cellular
degradation product in the body),
o alcohol,
o amoniac acid,
o drugs (neuroprotective effect);
GNC- Brain Health Formula
Efect II
57. o Reduces progressive loss of neurons caused by aging, traumatic
brain injury, brain ischemic processes by:
o stimulating neuronal neurogenesis and regeneration by action
similar to neuronal growth factors,
o reducing the degeneration of healthy neurons,
o Neuroplastic Effect = Brain Derived Neurotrophic Factor BDNF
GNC- Brain Health Formula
Efect III
58. o Reduces the symptoms of cranial nerve damage
(blindness, hearing loss, migraines, neuralgia);
o Cerebral antioxidant protection;
GNC- Brain Health Formula
Efect IV
59. Brain Health Formula
Efect V
Helps in:
• Learning
• Storage and playback of information,
• Improving verbal fluidity,
• Maintaining concentration, vigilance and
attention,
• Improving emotional state and sociability,
• Increasing adaptability
60. Helps in:
• Increasing motor capacity
• Improving synthesis and maintaining neurotransmitter levels:
• Acetylcholine
• dopamine,
• adrenalin,
• noradrenaline
to increase receptor sensitivity;
Brain Health Formula
Efects VI
61. Combination of ingredients that offer superior
properties to improve:
• Emotional State,
• Short and long term memory
• Concentration
• Attention
• Cognition
Helps in Alzheimer`s Disease and Dementia
prevention
Brain Health Formula
Indications
63. L-TYROSINE 1000 MG, 60 tb
• Este un aminoacid ce ofera suport pentru:
buna functionare a sistemului nervos,
fiind un precursor al neurotransmitatorilor
dopamina, norepinefrina si epinefrina;
imbunatatirea memoriei;
imbunatatirea performantei fizice;
reducerea stresului oxidativ.
• 60 capsule vegetale;
• Concentratie de 1000 mg/capsula;
• Certificat Kosher Vegetarian.
64. GNC L-THEANINE 200MG, 60 CPS
• L-Teanina este un aminoacid derivat din
frunzele de ceai negru, alb si mai ales de ceai
verde.
GNC L-Teanina 200 mg contine
Suntheanine® L-Teanina ce este forma
patentata si studiata clinic, pura 100%, cu
biodisponibilitate mare;
Studiile clinice umane au aratat ca
Suntheanine® promoveaza o stare de
relaxare fara somnolenta;
Imbunatateste viata de zi cu zi, performantele
de invatare, cresterea acuitatii mentale,
promovarea concentrarii si calitatea
somnului;
Nu contine zahar, coloranti artificiali, arome
artificiale, gluten, porumb, soia, lactate,
drojdii.
65. GNC GABA 750 MG, 90 CPS
• GABA este un aminoacid non-proteic, ce joaca un rol
cheie in sistemul nervos central al organismului;
Este un mediator inhibitor in creierul uman,
provocand relaxarea fizica si psihica;
Solutia naturala in tratamentul complementar al
starilor anxioase;
Poate imbunatati calitatea somnului;
Nu contine zahar, coloranti si arome artificiale,
sodiu, grau, gluten, porumb, soia, lactoza.
66. GNC 5-HTP 100 MG, 30 CPS
• Obtinut din seminte de Griffonia simplicifolia;
• 5-Hidroxitriptofanul este un precursor al
serotoninei, neurotransmitator al sistemului
nervos;
Solutia naturala in tratamentul complementar
al depresiei;
Demonstrat ca are un efect antidepresiv si
poate fi folosit in tratamentul migrenelor;
Formula imbunatatita cu vitamina B-6, care
contribuie la sinteza neurotransmitatorilor si la
functionarea normala a sistemului nervos.
