#WorldCancerDay 2014 PPT Presentation on #SlideShare via @DES_Journal
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Home = http://www.worldcancerday.org/ Cancer Myths = http://www.worldcancerday.org/cancer-myths Engage = http://www.worldcancerday.org/dosomething Events = http://www.worldcancerday.org/events-map Resources = http://www.worldcancerday.org/wcd-resources
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World Cancer Day 2013
Cancer affects millions of people worldwide each year. World Cancer Day, celebrated annually on February 4th, aims to raise awareness about cancer prevention, detection, and treatment. This poster encourages learning facts to dispel common myths about cancer on World Cancer Day 2013.
World cancer day 2015
Cancer is a major health problem in India and worldwide. The document discusses cancer causes, symptoms, stages, treatments, and approaches to control cancer including prevention, early detection, diagnosis and treatment, and palliative care. Prevention through healthy lifestyle choices and avoiding tobacco, alcohol, and other carcinogens is emphasized. Early detection greatly increases chances of successful treatment. The best treatment is decided by doctors based on cancer type and stage. Spreading awareness about cancer is important to fight this disease.
Diethylstilbestrol Transgenerational Neurodevelopmental Deficits
Collaborative on Health and the Environment Webinar, 20 March 2019.
Study : https://diethylstilbestrol.co.uk/multigenerational-neurodevelopmental-deficits/
Analysis : https://diethylstilbestrol.co.uk/transgenerational-neurodevelopmental-deficits/
DES transgenerational effects studies : https://diethylstilbestrol.co.uk/studies/transgenerational-effects/
What Does the Future Hold for Autism Families?
February 2017 presentation, by Jill Escher, MA, JD, via Germline Exposure, from the Autism in the Family Conference.
Sources : http://www.germlineexposures.org/what-does-the-future-hold.html
PDF : http://www.germlineexposures.org/uploads/6/4/0/9/6409433/whatdoesfutureholdforautismfamilies.pdf
Time Bomb : a Journey into Old Exposures, Gametic Glitches, and the Autism Ex...
This February 2017 presentation, by Jill Escher, MA, JD, via Germline Exposure, to a student-run chapter of SFN, explained the history and science behind the "Time Bomb" hypothesis of autism.
Sources : http://www.germlineexposures.org/sfn-wonder-feb-2017.html
PDF : http://www.germlineexposures.org/uploads/6/4/0/9/6409433/sfn_escher_slides.pdf
DES Update CDC 2003
SOURCES
CDC Resources and Educational Tools - Educational Tools for Clinicians
DES Lecture Presentation and DES Case Studies > http://www.cdc.gov/des/hcp/resources/tools_clinicians.html
CDC Resources and Educational Tools - Educational Tools for Nurses
DES Case Studies > http://www.cdc.gov/des/hcp/resources/tools_nurses.html
CDC Resources and Educational Tools - Clinician Information
DES References > http://www.cdc.gov/des/hcp/bibliography/index.html
MORE DES DIETHYLSTILBESTROL RESOURCES
DES cases and lawsuits:
http://diethylstilbestrol.co.uk/studies/des-lawsuits/
DES studies on cancers and screening:
https://desdaughter.com/2013/09/08/diethylstilbestrol-resources-1/
DES studies on epigenetics and transgenerational effects:
https://desdaughter.com/2015/12/16/diethylstilbestrol-resources-6/
DES studies on fertility:
http://diethylstilbestrol.co.uk/studies/des-and-fertility/
DES studies on gender identity and psychological health:
https://desdaughter.com/2015/12/04/diethylstilbestrol-resources-3/
DES studies on in-utero exposure to DES and side-effects:
https://desdaughter.com/2013/12/31/diethylstilbestrol-resources-4/
DES studies on pregnancy:
http://diethylstilbestrol.co.uk/studies/des-and-pregnancy/
DES studies on the genital tract:
https://desdaughter.com/2015/12/16/diethylstilbestrol-resources-7/
DES videos:
https://www.youtube.com/playlist?list=PL3D4F4A11812DAE00
Fracking Chemicals Disrupt Hormone Function
University of Missouri researchers have discovered that an oil and natural gas drilling technique called hydraulic fracturing uses chemicals that can disrupt the body's hormones. The researchers found that the endocrine-disrupting chemicals used in the process could interfere with a class of hormones that includes testosterone and estrogen. The findings were published in the journal Endocrinology.
News = http://medicine.missouri.edu/news/0214.php
Study = http://medicine.missouri.edu/news/docs/en.2013-1697.full.pdf
Increasing Trends in Male Reproductive Disorders, Environmental Exposures, an...
On this call, Dr. Skakkebaek presented his concerns about increasing trends in male reproductive disorders, including the significant global increase in incidence of germ cell tumors. He and colleagues from all over the world demonstrated that over half of all young men's semen quality does not meet the reference standard of the World Health Organization. Dr. Skakkebaek presented evidence linking testicular cancer, poor semen quality, childlessness, and rapidly decreasing fertility rates. He showed how there is little doubt that environmental factors, most likely associated with modern lifestyles, have - in a broad sense - had an adverse influence on male reproductive health. He and his group are examining a fundamental role that exposure to endocrine-disrupting chemicals may play in these trends, trends that in a few decades will result in decreasing populations in industrialized countries, and believes collaborative research is required to identify the causes of these adverse trends.
Sources: http://healthandenvironment.org/partnership_calls/18355
Recommended
World Cancer Day 2013
Cancer affects millions of people worldwide each year. World Cancer Day, celebrated annually on February 4th, aims to raise awareness about cancer prevention, detection, and treatment. This poster encourages learning facts to dispel common myths about cancer on World Cancer Day 2013.
World cancer day 2015
Cancer is a major health problem in India and worldwide. The document discusses cancer causes, symptoms, stages, treatments, and approaches to control cancer including prevention, early detection, diagnosis and treatment, and palliative care. Prevention through healthy lifestyle choices and avoiding tobacco, alcohol, and other carcinogens is emphasized. Early detection greatly increases chances of successful treatment. The best treatment is decided by doctors based on cancer type and stage. Spreading awareness about cancer is important to fight this disease.
Diethylstilbestrol Transgenerational Neurodevelopmental Deficits
Collaborative on Health and the Environment Webinar, 20 March 2019.
Study : https://diethylstilbestrol.co.uk/multigenerational-neurodevelopmental-deficits/
Analysis : https://diethylstilbestrol.co.uk/transgenerational-neurodevelopmental-deficits/
DES transgenerational effects studies : https://diethylstilbestrol.co.uk/studies/transgenerational-effects/
What Does the Future Hold for Autism Families?
February 2017 presentation, by Jill Escher, MA, JD, via Germline Exposure, from the Autism in the Family Conference.
Sources : http://www.germlineexposures.org/what-does-the-future-hold.html
PDF : http://www.germlineexposures.org/uploads/6/4/0/9/6409433/whatdoesfutureholdforautismfamilies.pdf
Time Bomb : a Journey into Old Exposures, Gametic Glitches, and the Autism Ex...
This February 2017 presentation, by Jill Escher, MA, JD, via Germline Exposure, to a student-run chapter of SFN, explained the history and science behind the "Time Bomb" hypothesis of autism.
Sources : http://www.germlineexposures.org/sfn-wonder-feb-2017.html
PDF : http://www.germlineexposures.org/uploads/6/4/0/9/6409433/sfn_escher_slides.pdf
DES Update CDC 2003
SOURCES
CDC Resources and Educational Tools - Educational Tools for Clinicians
DES Lecture Presentation and DES Case Studies > http://www.cdc.gov/des/hcp/resources/tools_clinicians.html
CDC Resources and Educational Tools - Educational Tools for Nurses
DES Case Studies > http://www.cdc.gov/des/hcp/resources/tools_nurses.html
CDC Resources and Educational Tools - Clinician Information
DES References > http://www.cdc.gov/des/hcp/bibliography/index.html
MORE DES DIETHYLSTILBESTROL RESOURCES
DES cases and lawsuits:
http://diethylstilbestrol.co.uk/studies/des-lawsuits/
DES studies on cancers and screening:
https://desdaughter.com/2013/09/08/diethylstilbestrol-resources-1/
DES studies on epigenetics and transgenerational effects:
https://desdaughter.com/2015/12/16/diethylstilbestrol-resources-6/
DES studies on fertility:
http://diethylstilbestrol.co.uk/studies/des-and-fertility/
DES studies on gender identity and psychological health:
https://desdaughter.com/2015/12/04/diethylstilbestrol-resources-3/
DES studies on in-utero exposure to DES and side-effects:
https://desdaughter.com/2013/12/31/diethylstilbestrol-resources-4/
DES studies on pregnancy:
http://diethylstilbestrol.co.uk/studies/des-and-pregnancy/
DES studies on the genital tract:
https://desdaughter.com/2015/12/16/diethylstilbestrol-resources-7/
DES videos:
https://www.youtube.com/playlist?list=PL3D4F4A11812DAE00
Fracking Chemicals Disrupt Hormone Function
University of Missouri researchers have discovered that an oil and natural gas drilling technique called hydraulic fracturing uses chemicals that can disrupt the body's hormones. The researchers found that the endocrine-disrupting chemicals used in the process could interfere with a class of hormones that includes testosterone and estrogen. The findings were published in the journal Endocrinology.
News = http://medicine.missouri.edu/news/0214.php
Study = http://medicine.missouri.edu/news/docs/en.2013-1697.full.pdf
Increasing Trends in Male Reproductive Disorders, Environmental Exposures, an...
On this call, Dr. Skakkebaek presented his concerns about increasing trends in male reproductive disorders, including the significant global increase in incidence of germ cell tumors. He and colleagues from all over the world demonstrated that over half of all young men's semen quality does not meet the reference standard of the World Health Organization. Dr. Skakkebaek presented evidence linking testicular cancer, poor semen quality, childlessness, and rapidly decreasing fertility rates. He showed how there is little doubt that environmental factors, most likely associated with modern lifestyles, have - in a broad sense - had an adverse influence on male reproductive health. He and his group are examining a fundamental role that exposure to endocrine-disrupting chemicals may play in these trends, trends that in a few decades will result in decreasing populations in industrialized countries, and believes collaborative research is required to identify the causes of these adverse trends.
Sources: http://healthandenvironment.org/partnership_calls/18355
Diethylstilbestrol Studies with Ethical Violations
1950’s illegal studies that violated the Hippocratic Oath, the Nuremberg Code, and the Declaration of Helsinki.
by Lacey-Clemens Friday, Nicole Skrabacz, Heather Perez
Read http://diethylstilbestrol.co.uk/des-tested-on-pregnant-women-without-consent/
World Cancer Day 2016 Key Messages
Taking place under the tagline ‘We can. I can.’, World Cancer Day 2016-2018 will explore how everyone – as a collective or as individuals – can do their part to reduce the global burden of cancer.
Just as cancer affects everyone in different ways, all people have the power to take various actions to reduce the impact that cancer has on individuals, families and communities.
World Cancer Day is a chance to reflect on what you can do, make a pledge and take action. Whatever you choose to do ‘We can. I can.’ make a difference to the fight against cancer.
WCD2016 website http://www.worldcancerday.org/ materials http://www.worldcancerday.org/materials and ways to help http://www.worldcancerday.org/get-involved
Endocrine disruptors in the healthcare sector
Created for healthcare professionals on EDCs, this slideshow by Health Care without Harm Europe (HCWH) examines the reasons why we should be concerned, who is at risk, including on pregnant women and babies, and where EDCs are hidden in the healthcare sector.
Sources: https://noharm-europe.org/documents/presentation-slides-webinar-edcs-healthcare
Leaflet: https://noharm-europe.org/documents/edc-leaflet-health-professionals
Methodology for EU EDC screening
European Commission Joint Research Center presents chemical screening methodology for the impact assessment on criteria to identify endocrine disruptors
A technical meeting on the JRC methodology for evidence screening of chemicals developed in the context of the Impact Assessment on criteria to identify Endocrine Disruptors took place on 6 November 2015 in Brussels.
The aim of this technical meeting was to present to Member States, Members of the European Parliament, countries from outside the EU and stakeholders the methodology developed by the JRC to estimate which chemicals may fall under the different options for criteria to identify endocrine disruptors as outlined in the roadmap. This methodology was developed in the framework of the impact assessment carried out by the European Commission on criteria to identify endocrine disruptors, in the context of the Plant Protection Products Regulation (EC) 1107/2009 and the Biocidal Products Regulation (EU) 528/2012.
Sources
* Methodology for EU EDC screening http://ec.europa.eu/health/endocrine_disruptors/docs/ev_20151106_co01_en.pdf
* Selection of chemical substances to be screened in the context of the impact assessment on criteria to identify endocrine disruptors http://ec.europa.eu/health/endocrine_disruptors/docs/impactassessment_chemicalsubstancesselection_en.pdf
Mammography Screening
Why was screening implemented?
What is overdiagnosis?
The evidence for overdiagnosis
Available data
Facts from recent studies
Risks of screening
The illusion of early detection
Harms due to overdiagnosis
Benefit-risk balance
So, what to do?
About mammograms: https://desdaughter.wordpress.com/tag/mammograms/
About overdiagnosis: https://desdaughter.wordpress.com/tag/overdiagnosis/
About screening: https://desdaughter.wordpress.com/tag/screening/
DES Sons
The Presence of Gender Dysphoria, Transsexualism, and Disorders of Sexual Differentiation in Males Prenatally Exposed to Diethylstilbestrol DES.
by Scott P. Kerlin, Ph.D.
MORE ABOUT DES:
DES Sons studies : https://desdaughter.wordpress.com/tag/des-sons/
DES studies on cancer, breast cancer, CCAC, vaginal cancer, screening: https://desdaughter.wordpress.com/2013/09/08/des-diethylsilbestrol-resources-by-ncbi-1/
DES studies on fertility, gender identity, pregnancy : https://desdaughter.wordpress.com/2014/04/04/des-diethylsilbestrol-resources-by-ncbi-3/
DES studies on in-utero exposure to DES and DES side-effects : https://desdaughter.wordpress.com/2013/12/31/des-diethylsilbestrol-resources-by-ncbi-2/
DES articles on lawsuits and various studies. : https://desdaughter.wordpress.com/2014/10/11/des-diethylsilbestrol-resources-by-ncbi-4/
DES Videos : https://www.youtube.com/playlist?list=PL3D4F4A11812DAE00
Dépister le Cancer du Sein ?
Une brochure permet de donner le choix aux femmes: visitez http://cancer-rose.fr/
Le dépistage organisé du cancer du sein, généralisé en France depuis 2004 et proposé aux femmes de 50 à 74 ans, fait l’objet de controverses. Celles-ci, publiées dans des revues scientifiques de premier plan, ont été longtemps minimisées auprès du grand public.
Les doutes portent sur un faible bénéfice et des risques avérés. Ces derniers sont essentiellement les fausses alertes, c’est à dire l’annonce d’une lésion mammographique qui ne s’avère pas réelle, et le surdiagnostic. Le surdiagnostic est la découverte d’un cancer qui n’aurait pas affecté la santé de la femme de son vivant, s’il n’avait pas été détecté. Le bénéfice s’avère beaucoup plus faible que présenté officiellement, en raison notamment du faible risque en valeur absolue de mourir de ce cancer, et de la faible efficacité du dépistage.
De ce constat est née une brochure indépendante, délivrant une information claire, qui se veut loyale, aussi complète que possible et facilement accessible. Elle est téléchargeable gratuitement directement sur la page d’accueil de "cancer rose".
Seize auteurs l’ont élaborée. Destinée à la lectrice concernée par le dépistage, elle est aussi pensée comme aide au praticien démuni face aux interrogations d’une patiente.
L’objectif de cette brochure, (unique en langue française alors qu’il en existe p.ex. en Allemagne pour les femmes) est de donner aux femmes le pouvoir de décider de façon rationnelle et sans être culpabilisées. Chacune se fera ainsi son opinion au travers des meilleures sources scientifiques disponibles. Même si le dépistage du cancer du sein est un programme dit de santé publique, il n’en reste pas moins que la participation est une décision individuelle qui ne peut être prise qu’en connaissance de cause, ni imposée ni subie.
Surdiagnostic des Cancers du Sein
Spécialiste de la mammographie, le Dr Bernard Duperray apporte aux radiologues francophones un enseignement indépendant des politiques de santé à la mode. Les observations cliniques et les résultats scientifiques présentés apportent la preuve des contradictions entre la représentation classique du cancer du sein et l’histoire naturelle des maladies cancéreuses du sein, hétérogène et imprévisible.
Consultez et téléchargez ci dessous le fichier de 76 diapositives passionnantes de la conférence de Bernard DUPERRAY et vous n’aurez plus de doutes sur la réalité du surdiagnostic dans le dépistage organisé du cancer du sein.
Sources:
http://www.formindep.org/Cours-de-senologie-de-Bernard.html
Les alternatives aux pesticides
Sommaire:
1/ Qu’est ce qu’un pesticide ?
2/ Répartition de la consommation de pesticides en France
3/ Grenelle 2 et plan ecophyto
4/ Comment réduire l’utilisation des pesticides en milieu agricole ?
5/ Production Intégrée, une autre forme d’agriculture
6/ Agriculture biologique
7/ Comment remplacer les pesticides en agriculture ?
8/ Zéro pesticide dans les collectivités
9/ Désherber sans chimie en zone urbaine
10/ Jardinage et usage domestiques
11/ Jardiner sans pesticides, comment faire ?
Téléchargez le nouvel appel à participation et diffusez le plus largement possible…
http://www.semaine-sans-pesticides.fr/wp-content/uploads/2014/09/Appel-%C3%A0-participation_SPAP_2015_FR.pdf
Visitez le site http://www.semaine-sans-pesticides.fr/
Nos posts tagués pesticides https://desdaughter.wordpress.com/tag/pesticides/
L'impact des pesticides sur la santé
Omniprésents dans notre environnement, les pesticides polluent l'air, les sols et les eaux souterraines ou de surface, mettant en danger de nombreuses espèces animales indispensables à notre survie.
Téléchargez le nouvel appel à participation et diffusez le plus largement possible…
http://www.semaine-sans-pesticides.fr/wp-content/uploads/2014/09/Appel-%C3%A0-participation_SPAP_2015_FR.pdf
Visitez le site http://www.semaine-sans-pesticides.fr/
Nos posts tagués pesticides https://desdaughter.wordpress.com/tag/pesticides/
La semaine pour les alternatives aux pesticides
La Semaine pour les alternatives aux pesticides est un événement national et international annuel du 20 au 30 mars pour informer sur l’impact des pesticides sur l’environnement et la santé. Durant la Semaine tout le monde est invité à organiser des évènements: particuliers, associations, agriculteurs, collectivités locales, entreprises, écoles… Pas besoin de gros moyens ou de beaucoup d’expérience. Avec un peu d’imagination, de volonté et d’organisation, il est facile de créer une action. Cet évènement est devenu le rendez-vous incontournable pour celles et ceux qui souhaitent construire un avenir sans pesticides. Cette initiative de l’association Générations Futures et de l’ACAP, collectif de 170 organisations, a été lancée en 2006 et depuis chaque édition connaît un succès croissant.
Téléchargez le nouvel appel à participation et diffusez le plus largement possible…
http://www.semaine-sans-pesticides.fr/wp-content/uploads/2014/09/Appel-%C3%A0-participation_SPAP_2015_FR.pdf
Visitez le site http://www.semaine-sans-pesticides.fr/
Nos posts tagués pesticides https://desdaughter.wordpress.com/tag/pesticides/
Cervical Cancer and HPV by CANSA
The United States Congress designated January as Cervical Health Awareness Month.
CANSA places the focus on Cervical Cancer during the month of September. Cervical Cancer is the 2nd most common cancer among South African women.
Sources: http://www.cansa.org.za/womens-health/
Prenatal Exposure to EDCs and Obesity
by the Collaborative on Health and the Environment
Prenatal Exposure to EDCs and Obesity: Combining Toxicology and Epidemiology with Dr. Juliette Legler
The incidence of childhood obesity has reached epidemic proportions globally and there is an urgent need to better understand the impact of early life exposure to chemical obesogens on the development of obesity. The European OBELIX (Obesogenic endocrine disrupting chemicals: linking prenatal exposure to the development of obesity later in life) project examined the hypothesis that prenatal exposure to endocrine disrupting compounds (EDCs) plays a role in the development of obesity later in life using a multidisciplinary approach that combined various approaches, including epidemiology and toxicology.
The project focused on assessing prenatal exposure to major classes of EDCs including dioxins and dioxin-like polychlorinated biphenyls, non-dioxin-like PCBs, brominated flame retardants, organochlorine pesticides, phthalates, and perfluorinated alkyl acids. Toxicological studies in OBELIX demonstrated that perinatal dietary exposure to representatives of these EDC classes resulted in metabolic changes that persisted into adulthood, long after termination of exposure at weaning, and that effects were compound- and sex-specific. The observed effects were not consistently towards an obese phenotype; a lean phenotype was also observed in animal studies for some compounds. Epidemiological studies in birth cohorts throughout Europe indicated associations between pre- and postnatal exposure to EDCs and early growth trajectories and body mass index in children up to 7 years.
This call reviewed the main findings of the largest project up to now to examine the obesogen hypothesis.
Sources: http://www.healthandenvironment.org/partnership_calls/14860
CLARITY BPA: a Novel Approach to study EDCs
by the Collaborative on Health and the Environment
On this call Retha Newbold, MS, Researcher Emeritus, National Toxicology Program, National Institute of Environmental Health Sciences, discussed the program called “The Consortium Linking Academic and Regulatory Insights on the Toxicity of Bisphenol A (CLARITY-BPA)” which is an interagency agreement, conducted under the auspices of the National Toxicology Program (NTP), between The National Institute of Environmental Health Sciences (NIEHS) supported grantees, the staff of the Division of the National Toxicology Program (DNTP) at NIH/NIEHS, and the Food and Drug Administration at the National Center for Toxicological Research (FDA/NCTR). The goals of the consortium are to enhance the utility of a perinatal 2-year GLP chronic toxicity study on BPA for regulatory decision-making by incorporating a wide range of doses and some additional disease-related endpoints that are not usually covered.
To this end, 12 NIEHS grantees are studying hypothesis-driven mechanisms by investigating specific endpoints that maybe altered by BPA including behavioral/neuroendocrine, immune function, cardiac, reproductive tract, cancer, thyroid, and other organ systems. This consortium is unique in that it combines the knowledge and skills of the NTP staff with experts from the academic field who are covering more mechanistic studies. Although this program focuses on BPA, it may provide an example of how to better study effects of other endocrine disrupting chemicals especially since numerous organ systems may be involved.
Sources: http://www.healthandenvironment.org/partnership_calls/14639
EAAD 2014 Resources Toolkit for Healthcare Professionals in England
Held every 18 November, European Antibiotic Awareness Day (EAAD) is a day to encourage responsible use of antibiotics.
The plan for EAAD 2014 is to increase measurable engagement by healthcare professionals and the public. Our main objective is that by 30th November we have a combined 10, 000 Antibiotic Guardian pledges from healthcare professionals and the public to at least one pledge for prudent use of antimicrobials.
Sources: https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/369778/EAAD-AG_Campaign_Resources_Toolkit_2014.pdf
Posters and Leaflets: https://www.gov.uk/government/publications/european-antibiotic-awareness-day-and-antibiotic-guardian-posters-and-leaflets
Video: http://youtu.be/7PhmyNBWGik?list=PL5iZsTMBd0hjSm71Z8WOYn3_CdPC09WCX
Website: http://antibioticguardian.com/
Dr. Philippe Grandjean on Chemical Brain Drain
How the Next Generation's Brain Functions are Endangered by EDCs and Other Environmental Chemicals
by the Collaborative on Health and the Environment
Dr. Philippe Grandjean suggests that new scientific insights reveal that the next generation's brain functions are endangered by environmental chemicals. The fetus is not protected by the placenta and therefore shares the mother's cumulated exposures to toxic chemicals. Infants and children are likewise exposed to a cocktail of foreign substances against which the body has no innate defense. Prenatal and early postnatal brain development is an extremely complex process that we now know is uniquely vulnerable. Lead, mercury and a few other substances have long been known to be toxic to brain development. Recent research suggests that many chemicals, perhaps thousands, may cause similar effects because they can gain access to the developing brain and exert their toxicity to brain cells. This new insight needs to be translated into public policy to protect the brain functions of the next generation. On this call Dr. Grandjean discussed what he terms "chemical brain drain" and how we might work to protect the brain health of future generations.
Sources: http://www.healthandenvironment.org/partnership_calls/14316?res
Effects of Prenatal Exposures to EDCs on Childhood Development
by the Collaborative on Health and the Environment
The call featured Dr. Frederica Perera who reviewed data from a longitudinal cohort study following mothers and children from pregnancy into adolescence. In this study, prenatal exposure to the combustion related air pollutants, polycyclic aromatic hydrocarbons, is associated with adverse neurodevelopmental outcomes as well as other disease endpoints. Prevention strategies were also discussed.
Sources: http://www.healthandenvironment.org/partnership_calls/14035
Endocrine Disruption of the Neuro-immune Interface
The document discusses the neuro-immune interface and how endocrine disrupting chemicals (EDCs) can impact the interactions between the nervous, immune, and endocrine systems, especially during development. It provides an example showing that hormone disruption during sensitive prenatal and early postnatal periods can influence brain sex development and adult sexual behavior through effects on immune cells in the brain called microglia. The summary concludes that more research is still needed to understand how EDC exposures may impact development by disrupting the complex interactions between the body's key regulatory systems during critical windows.
Endocrine Disruption and Immune Dysfunction
by the Collaborative on Health and the Environment
On this first in a series of calls on endocrine disrupting chemicals, Dr. Rodney Dietert discussed how the immune system is a target for endocrine disrupting chemicals, particularly during development. Numerous relatively ‘hidden’ effects can ensue from a single risk factor and emerge over a lifetime. He also discussed how current safety testing fails to appropriately assess misregulated inflammation as the greatest immune based health risk.
Sources: http://www.healthandenvironment.org/partnership_calls/13389
Maternal Bisphenol A Programs Offspring Metabolic Syndrome
by the Collaborative on Health and the Environment
On this call Drs. Ross and Desai presented evidence that prenatal exposure to EDCs, specifically the plastic component Bisphenol A, can increase the relative risk of adult obesity and metabolic syndrome. They also discussed the significance of these findings for neonatal and childhood care, and the need for strategies for the prevention and therapy of obesity to address programming effects of the early life environment.
Sources: http://www.healthandenvironment.org/partnership_calls/15308
More Related Content
More from DES Daughter
Diethylstilbestrol Studies with Ethical Violations
1950’s illegal studies that violated the Hippocratic Oath, the Nuremberg Code, and the Declaration of Helsinki.
by Lacey-Clemens Friday, Nicole Skrabacz, Heather Perez
Read http://diethylstilbestrol.co.uk/des-tested-on-pregnant-women-without-consent/
World Cancer Day 2016 Key Messages
Taking place under the tagline ‘We can. I can.’, World Cancer Day 2016-2018 will explore how everyone – as a collective or as individuals – can do their part to reduce the global burden of cancer.
Just as cancer affects everyone in different ways, all people have the power to take various actions to reduce the impact that cancer has on individuals, families and communities.
World Cancer Day is a chance to reflect on what you can do, make a pledge and take action. Whatever you choose to do ‘We can. I can.’ make a difference to the fight against cancer.
WCD2016 website http://www.worldcancerday.org/ materials http://www.worldcancerday.org/materials and ways to help http://www.worldcancerday.org/get-involved
Endocrine disruptors in the healthcare sector
Created for healthcare professionals on EDCs, this slideshow by Health Care without Harm Europe (HCWH) examines the reasons why we should be concerned, who is at risk, including on pregnant women and babies, and where EDCs are hidden in the healthcare sector.
Sources: https://noharm-europe.org/documents/presentation-slides-webinar-edcs-healthcare
Leaflet: https://noharm-europe.org/documents/edc-leaflet-health-professionals
Methodology for EU EDC screening
European Commission Joint Research Center presents chemical screening methodology for the impact assessment on criteria to identify endocrine disruptors
A technical meeting on the JRC methodology for evidence screening of chemicals developed in the context of the Impact Assessment on criteria to identify Endocrine Disruptors took place on 6 November 2015 in Brussels.
The aim of this technical meeting was to present to Member States, Members of the European Parliament, countries from outside the EU and stakeholders the methodology developed by the JRC to estimate which chemicals may fall under the different options for criteria to identify endocrine disruptors as outlined in the roadmap. This methodology was developed in the framework of the impact assessment carried out by the European Commission on criteria to identify endocrine disruptors, in the context of the Plant Protection Products Regulation (EC) 1107/2009 and the Biocidal Products Regulation (EU) 528/2012.
Sources
* Methodology for EU EDC screening http://ec.europa.eu/health/endocrine_disruptors/docs/ev_20151106_co01_en.pdf
* Selection of chemical substances to be screened in the context of the impact assessment on criteria to identify endocrine disruptors http://ec.europa.eu/health/endocrine_disruptors/docs/impactassessment_chemicalsubstancesselection_en.pdf
Mammography Screening
Why was screening implemented?
What is overdiagnosis?
The evidence for overdiagnosis
Available data
Facts from recent studies
Risks of screening
The illusion of early detection
Harms due to overdiagnosis
Benefit-risk balance
So, what to do?
About mammograms: https://desdaughter.wordpress.com/tag/mammograms/
About overdiagnosis: https://desdaughter.wordpress.com/tag/overdiagnosis/
About screening: https://desdaughter.wordpress.com/tag/screening/
DES Sons
The Presence of Gender Dysphoria, Transsexualism, and Disorders of Sexual Differentiation in Males Prenatally Exposed to Diethylstilbestrol DES.
by Scott P. Kerlin, Ph.D.
MORE ABOUT DES:
DES Sons studies : https://desdaughter.wordpress.com/tag/des-sons/
DES studies on cancer, breast cancer, CCAC, vaginal cancer, screening: https://desdaughter.wordpress.com/2013/09/08/des-diethylsilbestrol-resources-by-ncbi-1/
DES studies on fertility, gender identity, pregnancy : https://desdaughter.wordpress.com/2014/04/04/des-diethylsilbestrol-resources-by-ncbi-3/
DES studies on in-utero exposure to DES and DES side-effects : https://desdaughter.wordpress.com/2013/12/31/des-diethylsilbestrol-resources-by-ncbi-2/
DES articles on lawsuits and various studies. : https://desdaughter.wordpress.com/2014/10/11/des-diethylsilbestrol-resources-by-ncbi-4/
DES Videos : https://www.youtube.com/playlist?list=PL3D4F4A11812DAE00
Dépister le Cancer du Sein ?
Une brochure permet de donner le choix aux femmes: visitez http://cancer-rose.fr/
Le dépistage organisé du cancer du sein, généralisé en France depuis 2004 et proposé aux femmes de 50 à 74 ans, fait l’objet de controverses. Celles-ci, publiées dans des revues scientifiques de premier plan, ont été longtemps minimisées auprès du grand public.
Les doutes portent sur un faible bénéfice et des risques avérés. Ces derniers sont essentiellement les fausses alertes, c’est à dire l’annonce d’une lésion mammographique qui ne s’avère pas réelle, et le surdiagnostic. Le surdiagnostic est la découverte d’un cancer qui n’aurait pas affecté la santé de la femme de son vivant, s’il n’avait pas été détecté. Le bénéfice s’avère beaucoup plus faible que présenté officiellement, en raison notamment du faible risque en valeur absolue de mourir de ce cancer, et de la faible efficacité du dépistage.
De ce constat est née une brochure indépendante, délivrant une information claire, qui se veut loyale, aussi complète que possible et facilement accessible. Elle est téléchargeable gratuitement directement sur la page d’accueil de "cancer rose".
Seize auteurs l’ont élaborée. Destinée à la lectrice concernée par le dépistage, elle est aussi pensée comme aide au praticien démuni face aux interrogations d’une patiente.
L’objectif de cette brochure, (unique en langue française alors qu’il en existe p.ex. en Allemagne pour les femmes) est de donner aux femmes le pouvoir de décider de façon rationnelle et sans être culpabilisées. Chacune se fera ainsi son opinion au travers des meilleures sources scientifiques disponibles. Même si le dépistage du cancer du sein est un programme dit de santé publique, il n’en reste pas moins que la participation est une décision individuelle qui ne peut être prise qu’en connaissance de cause, ni imposée ni subie.
Surdiagnostic des Cancers du Sein
Spécialiste de la mammographie, le Dr Bernard Duperray apporte aux radiologues francophones un enseignement indépendant des politiques de santé à la mode. Les observations cliniques et les résultats scientifiques présentés apportent la preuve des contradictions entre la représentation classique du cancer du sein et l’histoire naturelle des maladies cancéreuses du sein, hétérogène et imprévisible.
Consultez et téléchargez ci dessous le fichier de 76 diapositives passionnantes de la conférence de Bernard DUPERRAY et vous n’aurez plus de doutes sur la réalité du surdiagnostic dans le dépistage organisé du cancer du sein.
Sources:
http://www.formindep.org/Cours-de-senologie-de-Bernard.html
Les alternatives aux pesticides
Sommaire:
1/ Qu’est ce qu’un pesticide ?
2/ Répartition de la consommation de pesticides en France
3/ Grenelle 2 et plan ecophyto
4/ Comment réduire l’utilisation des pesticides en milieu agricole ?
5/ Production Intégrée, une autre forme d’agriculture
6/ Agriculture biologique
7/ Comment remplacer les pesticides en agriculture ?
8/ Zéro pesticide dans les collectivités
9/ Désherber sans chimie en zone urbaine
10/ Jardinage et usage domestiques
11/ Jardiner sans pesticides, comment faire ?
Téléchargez le nouvel appel à participation et diffusez le plus largement possible…
http://www.semaine-sans-pesticides.fr/wp-content/uploads/2014/09/Appel-%C3%A0-participation_SPAP_2015_FR.pdf
Visitez le site http://www.semaine-sans-pesticides.fr/
Nos posts tagués pesticides https://desdaughter.wordpress.com/tag/pesticides/
L'impact des pesticides sur la santé
Omniprésents dans notre environnement, les pesticides polluent l'air, les sols et les eaux souterraines ou de surface, mettant en danger de nombreuses espèces animales indispensables à notre survie.
Téléchargez le nouvel appel à participation et diffusez le plus largement possible…
http://www.semaine-sans-pesticides.fr/wp-content/uploads/2014/09/Appel-%C3%A0-participation_SPAP_2015_FR.pdf
Visitez le site http://www.semaine-sans-pesticides.fr/
Nos posts tagués pesticides https://desdaughter.wordpress.com/tag/pesticides/
La semaine pour les alternatives aux pesticides
La Semaine pour les alternatives aux pesticides est un événement national et international annuel du 20 au 30 mars pour informer sur l’impact des pesticides sur l’environnement et la santé. Durant la Semaine tout le monde est invité à organiser des évènements: particuliers, associations, agriculteurs, collectivités locales, entreprises, écoles… Pas besoin de gros moyens ou de beaucoup d’expérience. Avec un peu d’imagination, de volonté et d’organisation, il est facile de créer une action. Cet évènement est devenu le rendez-vous incontournable pour celles et ceux qui souhaitent construire un avenir sans pesticides. Cette initiative de l’association Générations Futures et de l’ACAP, collectif de 170 organisations, a été lancée en 2006 et depuis chaque édition connaît un succès croissant.
Téléchargez le nouvel appel à participation et diffusez le plus largement possible…
http://www.semaine-sans-pesticides.fr/wp-content/uploads/2014/09/Appel-%C3%A0-participation_SPAP_2015_FR.pdf
Visitez le site http://www.semaine-sans-pesticides.fr/
Nos posts tagués pesticides https://desdaughter.wordpress.com/tag/pesticides/
Cervical Cancer and HPV by CANSA
The United States Congress designated January as Cervical Health Awareness Month.
CANSA places the focus on Cervical Cancer during the month of September. Cervical Cancer is the 2nd most common cancer among South African women.
Sources: http://www.cansa.org.za/womens-health/
Prenatal Exposure to EDCs and Obesity
by the Collaborative on Health and the Environment
Prenatal Exposure to EDCs and Obesity: Combining Toxicology and Epidemiology with Dr. Juliette Legler
The incidence of childhood obesity has reached epidemic proportions globally and there is an urgent need to better understand the impact of early life exposure to chemical obesogens on the development of obesity. The European OBELIX (Obesogenic endocrine disrupting chemicals: linking prenatal exposure to the development of obesity later in life) project examined the hypothesis that prenatal exposure to endocrine disrupting compounds (EDCs) plays a role in the development of obesity later in life using a multidisciplinary approach that combined various approaches, including epidemiology and toxicology.
The project focused on assessing prenatal exposure to major classes of EDCs including dioxins and dioxin-like polychlorinated biphenyls, non-dioxin-like PCBs, brominated flame retardants, organochlorine pesticides, phthalates, and perfluorinated alkyl acids. Toxicological studies in OBELIX demonstrated that perinatal dietary exposure to representatives of these EDC classes resulted in metabolic changes that persisted into adulthood, long after termination of exposure at weaning, and that effects were compound- and sex-specific. The observed effects were not consistently towards an obese phenotype; a lean phenotype was also observed in animal studies for some compounds. Epidemiological studies in birth cohorts throughout Europe indicated associations between pre- and postnatal exposure to EDCs and early growth trajectories and body mass index in children up to 7 years.
This call reviewed the main findings of the largest project up to now to examine the obesogen hypothesis.
Sources: http://www.healthandenvironment.org/partnership_calls/14860
CLARITY BPA: a Novel Approach to study EDCs
by the Collaborative on Health and the Environment
On this call Retha Newbold, MS, Researcher Emeritus, National Toxicology Program, National Institute of Environmental Health Sciences, discussed the program called “The Consortium Linking Academic and Regulatory Insights on the Toxicity of Bisphenol A (CLARITY-BPA)” which is an interagency agreement, conducted under the auspices of the National Toxicology Program (NTP), between The National Institute of Environmental Health Sciences (NIEHS) supported grantees, the staff of the Division of the National Toxicology Program (DNTP) at NIH/NIEHS, and the Food and Drug Administration at the National Center for Toxicological Research (FDA/NCTR). The goals of the consortium are to enhance the utility of a perinatal 2-year GLP chronic toxicity study on BPA for regulatory decision-making by incorporating a wide range of doses and some additional disease-related endpoints that are not usually covered.
To this end, 12 NIEHS grantees are studying hypothesis-driven mechanisms by investigating specific endpoints that maybe altered by BPA including behavioral/neuroendocrine, immune function, cardiac, reproductive tract, cancer, thyroid, and other organ systems. This consortium is unique in that it combines the knowledge and skills of the NTP staff with experts from the academic field who are covering more mechanistic studies. Although this program focuses on BPA, it may provide an example of how to better study effects of other endocrine disrupting chemicals especially since numerous organ systems may be involved.
Sources: http://www.healthandenvironment.org/partnership_calls/14639
EAAD 2014 Resources Toolkit for Healthcare Professionals in England
Held every 18 November, European Antibiotic Awareness Day (EAAD) is a day to encourage responsible use of antibiotics.
The plan for EAAD 2014 is to increase measurable engagement by healthcare professionals and the public. Our main objective is that by 30th November we have a combined 10, 000 Antibiotic Guardian pledges from healthcare professionals and the public to at least one pledge for prudent use of antimicrobials.
Sources: https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/369778/EAAD-AG_Campaign_Resources_Toolkit_2014.pdf
Posters and Leaflets: https://www.gov.uk/government/publications/european-antibiotic-awareness-day-and-antibiotic-guardian-posters-and-leaflets
Video: http://youtu.be/7PhmyNBWGik?list=PL5iZsTMBd0hjSm71Z8WOYn3_CdPC09WCX
Website: http://antibioticguardian.com/
Dr. Philippe Grandjean on Chemical Brain Drain
How the Next Generation's Brain Functions are Endangered by EDCs and Other Environmental Chemicals
by the Collaborative on Health and the Environment
Dr. Philippe Grandjean suggests that new scientific insights reveal that the next generation's brain functions are endangered by environmental chemicals. The fetus is not protected by the placenta and therefore shares the mother's cumulated exposures to toxic chemicals. Infants and children are likewise exposed to a cocktail of foreign substances against which the body has no innate defense. Prenatal and early postnatal brain development is an extremely complex process that we now know is uniquely vulnerable. Lead, mercury and a few other substances have long been known to be toxic to brain development. Recent research suggests that many chemicals, perhaps thousands, may cause similar effects because they can gain access to the developing brain and exert their toxicity to brain cells. This new insight needs to be translated into public policy to protect the brain functions of the next generation. On this call Dr. Grandjean discussed what he terms "chemical brain drain" and how we might work to protect the brain health of future generations.
Sources: http://www.healthandenvironment.org/partnership_calls/14316?res
Effects of Prenatal Exposures to EDCs on Childhood Development
by the Collaborative on Health and the Environment
The call featured Dr. Frederica Perera who reviewed data from a longitudinal cohort study following mothers and children from pregnancy into adolescence. In this study, prenatal exposure to the combustion related air pollutants, polycyclic aromatic hydrocarbons, is associated with adverse neurodevelopmental outcomes as well as other disease endpoints. Prevention strategies were also discussed.
Sources: http://www.healthandenvironment.org/partnership_calls/14035
Endocrine Disruption of the Neuro-immune Interface
The document discusses the neuro-immune interface and how endocrine disrupting chemicals (EDCs) can impact the interactions between the nervous, immune, and endocrine systems, especially during development. It provides an example showing that hormone disruption during sensitive prenatal and early postnatal periods can influence brain sex development and adult sexual behavior through effects on immune cells in the brain called microglia. The summary concludes that more research is still needed to understand how EDC exposures may impact development by disrupting the complex interactions between the body's key regulatory systems during critical windows.
Endocrine Disruption and Immune Dysfunction
by the Collaborative on Health and the Environment
On this first in a series of calls on endocrine disrupting chemicals, Dr. Rodney Dietert discussed how the immune system is a target for endocrine disrupting chemicals, particularly during development. Numerous relatively ‘hidden’ effects can ensue from a single risk factor and emerge over a lifetime. He also discussed how current safety testing fails to appropriately assess misregulated inflammation as the greatest immune based health risk.
Sources: http://www.healthandenvironment.org/partnership_calls/13389
Maternal Bisphenol A Programs Offspring Metabolic Syndrome
by the Collaborative on Health and the Environment
On this call Drs. Ross and Desai presented evidence that prenatal exposure to EDCs, specifically the plastic component Bisphenol A, can increase the relative risk of adult obesity and metabolic syndrome. They also discussed the significance of these findings for neonatal and childhood care, and the need for strategies for the prevention and therapy of obesity to address programming effects of the early life environment.
Sources: http://www.healthandenvironment.org/partnership_calls/15308
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Diethylstilbestrol Studies with Ethical Violations
Diethylstilbestrol Studies with Ethical Violations
EAAD 2014 Resources Toolkit for Healthcare Professionals in England
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Effects of Prenatal Exposures to EDCs on Childhood Development
Effects of Prenatal Exposures to EDCs on Childhood Development
Endocrine Disruption of the Neuro-immune Interface
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There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
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The Electrocardiogram - Physiologic Principles
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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