1. Kenneth Lipstock, MD
Lipstock LASIK and Cataract Center
Richmond, Virginia
www.lipstocklaser.com

2. Introduction: MAST 1 Study
 Prospective evaluation of 53 consecutive patients with nanoFLEX
(STAAR aspheric single piece collamer iol) between 7/09 and
5/10 (Lipstock)
 Measured 6-8 weeks Post-Op
 (“nanoFLEX MAST”)

 Prospective evaluation of 47 consecutive patients presenting in
office for routine follow up 7/09 to 5/10
 All with STAAR non-aspheric collamer plate IOL(CC4204BF) from 7/01 to 1 1/08
(Lipstock)
 (“BF MAST”)

3. MAST 1 Study
Distance-Corrected Bilateral Average Near (40cm) &
Intermediate (80cm) Visual Acuity
0
10
20
30
40
50
60
nanoFLEX nanoFLEX
20/20 Subset
BF Spherical
SnellenAcuity20/-
Near
Intermediate
20/53 20/53 20/52
20/24 20/24
20/26

4. MAST 2 STUDY
 To evaluate the near and intermediate
visual outcomes of patients undergoing
routine cataract surgery with
phacoemulsification and monofocal IOL
placement in the capsular bag in at least
one eye
Purpose:

5. Methods
 Prospective, multicenter evaluation of over 100
consecutive patients undergoing cataract surgery
with different monofocal IOLs
 Study evaluation consisted of a single visit 1-2
months postoperatively
 Outcome measures included monocular DC near
and intermediate VA and binocular acuities if eyes
were bilaterally implanted with the same lens

6. Inclusion Criteria
 Patients who underwent routine cataract surgery
with phacoemulsification and monofocal IOL
placement in the capsular bag in at least one eye
within the last 36 months
 At least 1 month postop before follow-up evaluation
 All Patients must have a DCVA of 20/25 or better

7. nanoFLEX Distance-Corrected Bilateral
Average Near & Intermediate VA
0
10
20
30
40
50
nanoFLEX
SnellenAcuity20/-
Near
Intermediate
20/50
20/24

8. NanoFLEX Binocular VA at Near (40cm) and
Intermediate (80 cm)
0%
5%
10%
15%
20%
25%
30%
35%
40%
45%
50%
20/16 20/20 20/25 20/32 20/40 20/50 20/63 20/80
10%
22%
48%
21%
2%
10%
21%
40%
24%
5%
%ofPatients
Intermediate (Average = 20/24) Near ( Average = 20/50)
n = 63

9. NanoFLEX Binocular VA at Near (40cm) and
Intermediate (80 cm) – Cumulative Eyes
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
20/16 20/20 20/25 20/32 20/40 20/50 20/63 20/80
10%
32%
79%
100%
2%
11%
32%
71%
95%
100%
%ofPatients
Intermediate ( Average = 20/24) Near (Average = 20/50)
n = 63

10. All Lenses
Distance-Corrected Bilateral Average Near & Intermediate VA
0
10
20
30
40
50
60
Near Intermediate
SnellenAcuity20/-
NanoFLEX (n=63)
AMO Tecnis
sililcone aspheric 3
piece iol (n=61)
20/50
20/24
20/28
20/52
p = 0.832
p = 0.072

11. Binocular VA at Near (40 cm): All Lenses
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
20/40 or
Better
20/50 or
Better
20/63 or
Better
20/80 or
Better
32%
71%
95%
100%
46%
72%
79%
93%
%ofPatients
NanoFLEX (n=63)
AMO Tecnis sililcone aspheric 3
piece iol (n=61)
p = 0.006
p = 0.112

12. Binocular VA at Intermediate (80 cm): All Lenses
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
20/20 or Better 20/25 or Better 20/32 or Better 20/40 or Better
35%
79%
100% 100%
34%
74%
82%
93%
%ofPatients
NanoFLEX (n=63)
AMO Tecnis sililcone aspheric 3
piece iol (n=61)
p = <0.001

13. Comparison to Multifocal and
Accommodative IOLs
Lens Investigator
Binocular
Distance Corrected
Near VA at 40cm
Binocular
Distance Corrected
Intermediate VA at 80cm
NanoFlex Lipstock 20/50 20/24
Restor D1
Santhiago 20/21 -
Maxwell - 20/30 at 70cm
Alfonso 20/18 20/28 at 70cm
Kohnen 20/22 20/29 at 70cm
Tecnis MF Hutz 20//27 20/26
Crystalens
Pepose 20/32 20/17
Alio 20/25 -
Synchrony Bohorquez 20/27 -

14. Conclusions
 The nanoFLEX lens offers patients a highly
effective cost-effective alternative to the “premium
channel” IOLs, by providing some near vision
and excellent intermediate vision.
 An additional prospective study designed to
evaluate how best to utilize the intrinsic properties
of the nanoFLEX to optimize visual outcomes with
a “blended vision” approach was subsequently
conducted.