The document outlines 6 strategies for successful long-term weight loss: 1) Make sure you are ready to make permanent lifestyle changes, 2) Find internal motivation by making a list of reasons to lose weight, 3) Set realistic weight loss goals such as 1-2 pounds per week, 4) Enjoy healthier foods high in plants and limit sugar and fat, 5) Get regular physical activity at least 30 minutes per day to burn more calories, and 6) Change your perspective by assessing challenges and planning how to deal with setbacks to maintain lifestyle changes.