Wednesday 5 andreas lasesson max iv laboratory
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The MAX IV Laboratory is a national synchrotron facility located at Lund University with an annual budget of €11M. It consists of the existing MAX-lab facility and the new MAX IV project, which will make it the brightest soft X-ray source in the world when completed in 2016. MAX IV will study materials using electromagnetic radiation, attracting nearly 1000 users annually from academia and industry to conduct research in fields such as materials science, chemistry, and biology. Some examples of research include studies of bone, semiconductors, proteins, and catalysts.
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Wednesday 5 andreas lasesson max iv laboratory
- 3. The MAX IV Laboratory ● A national laboratory at Lund University ● Financed by the Swedish Research Council ● Annual budget of €11M ● Consists of present MAX‐lab and the MAX IV project ● Nearly 1000 users each year ● Materials Science
- 4. What is a synchrotron facility? ● An accelerator of electrons ● Produce electromagnetic radiation from infrared to hard X‐rays ● Used for materials science
- 7. What materials can be studied? ● Biomaterials: bone, implants, prosthesis etc. ● Biomolecules: proteins etc. ● Semiconductors ● Liquids: oil, emulsions etc. ● Polymers: plastics etc. ● Chemicals: catalysts etc. ● Fossils
- 8. MAX‐lab ● Three synchrotron rings: MAX I –III ● Producing radiation from infrared to hard X‐rays ● 15 Beamlines for various experiments
- 9. 2016: The MAX IV facility ● Largest research infrastructure project in Sweden ● Will form a world leading centre for Materials Science in Lund together with ESS ● Will attract researchers and companies from the entire world
- 10. Linac (300m) ‐ 2014 1.5 GeV ring (96m) ‐ 2016 3 GeV ring (528m) ‐ 2015 The layout of MAX IV
- 11. What is so special about MAX IV? ● Constructed using novel accelerator technology developed in Lund ● Will be the brightest source of soft X‐rays in the World ● Enables: – Very fast measurements – Dilute samples – Very small samples – Imaging – Etc.
- 12. MAX IV and ESS ● Will form a Materials Science hub in Southern Sweden ● The Science Village will be built around the facilities ● Thousands of researchers visiting annually ● Cross‐road between academic research and industrial R&D
- 14. The MAX IV budget ● Total cost for buildings: €250M ● Costs for accelerators €150M provided by four organisations: – Swedish Research Council – VINNOVA ‐ Sweden’s Innovation Agency – Lund University – Region Skåne ● The first seven beamlines (€60M): – Knut & Alice Wallenberg Foundation – Swedish Universities ● 8th beamline “FinEst” funded by Estonia and Finland (€3M) ● Additional beamlines under negotiation within Sweden and internationally
- 15. What properties can be studied? ● Largest research infrastructure in Sweden ● Will attract researchers world‐wide to Lund ● Constructing the MAX IV The first 7 beamlines at MAX IV
- 16. ● FemtoMAX: ultrafast chemical reactions ● NanoMAX: 10 nanometer resolution, nanomaterials ● Balder: chemical processes, trace elements ● BioMAX: structures of biomolecules ● VERITAS: sub‐nanometer and femtosecond dynamics ● ARPES: nanosystems, new materials, semiconductors etc. ● HIPPIE: surface science, catalysis, corrosion, semiconductor research, et. The first 7 beamlines at MAX IV
- 18. New clues for treatments of heart disease ● Muscle cells are controlled through rising and falling levels of Calcium ions within the cell ● Calcium controlled by a membrane protein (SERCA) ● Reduced functionality of the SERCA pump associated with heart disease ● Researchers investigated SERCA at MAX‐lab ● Published in Nature in March 2013
- 19. Novo Nordisk Underwood et al., The Journal of Biological Chemistry, Vol. 285, pp. 723–730 Blue ribbon: Glucagon-like Peptide-1 (GLP-1) GLP-1 stimulates insulin production in the human body • Reduces and controls blood sugar • Reduces body weight Structure of GLP-1 together with receptor GLP-1R solved using the MX beamline at MAX-lab The GLP-1 analog Liraglutide is marketed as the type-2 diabetes drug Victoza by Novo Nordisk.
- 20. XAS (X‐ray Absorption Spectroscopy) X‐rays Sample: • Liquid • Solid • Biomaterial • Polymer • Wood • ... Sensitive to the chemical surroundings of transition metals: • Oxidation states • Coordination number • Bond lengths • ...
- 21. Imaging at MAX IV Method: Imaging in 2D & 3D Scientific scope: • Physiological and morphological characterization of tissue samples and entire organs • micro‐localization of toxic elements and tumor‐ targeting molecules in tissue • in‐vivo imaging of small animals Sectors: Life science, biological science incl. food, wood and plant science
- 22. Commercial users
- 24. 13/05/201324 An Industry Liaison Office for MAX IV Industrial Liaison Office Company Beamline scientists • Discussing initial problem • Negotiating legal agreement • Introductions to scientific staff • Quotes for beamtime • Science Link Technicians etc. Also working towards general public and industry, e.g. visiting industry fairs etc. • In‐depth scientific discussions • Planning beamtime • Sample preparation • Tutoring company users • Performing experiments • Data analysis