To develop a virtual reality game, you need hardware like a VR headset and motion controllers, as well as a capable PC or console. Essential software includes VR development environments such as Unity3D and Unreal Engine, along with SDKs for the targeted platform, and tools for 3D modeling, texturing, and audio editing. Strong skills in programming, 3D design, user experience design, and problem-solving are vital, often requiring collaboration among a diverse team.