Distraction osteogenesis, also called callus distraction, callotasis and osteodistraction, is a process used in orthopedic surgery, podiatric surgery, and oral and maxillofacial surgery to repair skeletal deformities and in reconstructive surgery
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Use of distraction osteogenesis in orthognathic surgery
1. Use of distraction osteogenesis in orthognathic surgery
DR MAMOON MAARWAT
PG RESIDENT MDS ORTHODONTICS PGY-III
SARDAR BEGUM DENTAL HOSPITAL GANDHARA UNIVERSITY PESHAWAR
2. Contents
Introduction.
Biology & stages of distraction osteogenesis.
Types of distraction osteogenesis & distractors.
DO in preparation for orthognathic surgery.
DO in lieu of conventional orthognathic surgery.
Summary
4. Introduction
Distraction osteogenesis has been used for lengthening of bones since the
earlier 20th century.
DO was adapted to the craniofacial skeleton in dogs by Snyder in 1973.
McCarthy is credited with popularizing the technique in humans with his
1992 publication of mandibular DO in patients with
o Hemifacial microsomia and Nager syndrome.
McCarthy JG, Schreiber J, Karp N, Thorne CH, Grayson BH. Lengthening the
human mandible by gradual distraction. Plast Reconstr Surg. 1992;89:1–8.
5. Introduction cont…
Advantages of distraction osteogenesis compared to conventional
technique
o Larges bony movement
o Concimitant expansion of surrounding soft tissues
o Neurovascular structures
o Greater stability
o Eliminates the need for bone graft and associated donor site morbidity
o Blood loss and hospital stay
6. Introduction cont….
Disadvantages include
o High degree of patient compliance.
o Total treatment time.
o Potential for device failure.
o Second operation is required for device removal.
o Vector of the movement is difficult to control.
8. Biology & stages of distraction osteogenesis
Slow expansion and controlled microtrauma in DO
Bone formation in DO gap occurs through intramembranous bone
formation
Mediated by series of growth factors, cytokines & ECM proteins.
Three stages
o Latency
o Distraction
o consolidation
9. Biology & stages of distraction osteogenesis
BONE
OSTEOTOMY CUT
LATENCY PERIOD
Primary bone callus
DISTRACTION PHASE
CONSOLIDATION
11. Types of distraction osteogenesis and distraction
devices
Three types of distraction osteogenesis
1. Monofocal
2. Bifocal
3. Trifocal
12. Types of distraction osteogenesis and distraction devices
Monofocal distraction osteogenesis:
o Simplest form of DO is the creation of a“dis-traction gap” by
slow separation of two cut bone sur-face
o Serves to augment a region of existing bone
New
Bone
13. Types of distraction osteogenesis and distraction devices
Bifocal distraction osteogenesis:
In this approach, a“transport segment”of bone is distracted from
one side of the defect to the other.
Used to fill a continuity defect, after tumor resection, or construct a
missing portion of bone, as in a congenital ramus deformity.
Transport
fragment
14. Types of distraction osteogenesis and distraction devices
Trifocal distraction:
o Trifocal DO is a modification of the bifocal technique
o Two transport seg-ments are created- one on each side of a larger
defect- and they are distracted toward one another until they meet.
o Use full in larger defects
TS TS
15. Types of distraction osteogenesis and distraction devices
Distraction devices:
o Necessary to facilitate controlled, gradual separation of the
osteotomized segments during the distraction phase
o To stabilize segments to promote ossification during consolidation
phase
16. Types of distraction osteogenesis and distraction devices
Choice of device based on :
o Type and location of movement planned
o Surgical access for osteotomy and device placement
o Rigidity of device needed
o Characteristic of the bone to which device is placed
o Desired vector movement
17. Types of distraction osteogenesis and distraction devices
Craniofacial distraction osteogenesis devices
Internal External
• Unirectional
• Bidirection
• multidirectional
Bone -borne
Tooth-borne
Bone-borne
Hybrid Sub-cutaneous
Intra - oral Extra-mucosal
Sub-mucosal
18. Types of distraction osteogenesis and distraction devices
Advantages of external devices include
o Easier application and removal.
o Improved access to the device mechanism to manage malfunction
compared to internal devices.
Disadvantages include ED may leave scars as the pins travel
through the skin, less stable, easily damaged by head movement
19. Types of distraction osteogenesis and distraction devices
Internal devices
o Difficult to place
o Always require a second opera-tion for removal
o More stable
o Do not leave pin scars
o More socially acceptable
21. DO in preparation for orthognathic surgery
Distraction osteogenesis techniques are useful to the orthognathic
surgeon both in coordination with and in preparation for other
orthognathic procedures
22. DO in preparation for orthognathic surgery
1. Surgically assisted maxillary expansion (SAME)
o Most common use of DO techniques prior to orthognathic surgery is
for management of maxillomandibular transverse discrepancies
o Rapid expansion is performed prior to fusion of MPS
o In adults maxillary expansion achieved only via SAME
23. DO in preparation for orthognathic surgery
When patient presented with absolute maxilla mandibular
transverse discripency orthodontist have several options
o Orthodontic resolution of discrepancy via dental tipping.
o Non-surgical orthopedic resolution of discrep-ancy via
maxillary distraction using a tooth-borne or bone-borne device
o Surgically assisted maxillary expansion prior to fixed appliance
treatment and/or orthog-nathic surgery
24. DO in preparation for orthognathic surgery
Advantages of a SAME procedure compared to a segmental
osteotomy include
o Equal widening of entire maxilla
o Increase in arch length
o Ability to create larger movements that can be achieved with lefort 1
osteotomy
o No need for bone grafting
25. DO in preparation for orthognathic surgery
Advantages of a segmental Le Fort I osteotomy are
o Single rather than staged operations
o Decreased total treatment time
o Lack of creation of a temporary diastema between the central
incisor teeth, which occurs with SAME
o Slightly decreased transverse relapse rate
26. DO in preparation for orthognathic surgery
2. Distraction in congenital and acquired craniofacial deformities
o Many patients presenting for orthognathic surgery will have had prior DO for
management of congenital or acquired craniofacial deformities in child hood.
Patient with craniofacial anomalies may have had DO prior to distraction
ostogenesis these include:
27. DO in preparation for orthognathic surgery
These include patient with
1. Pierre Robin sequence.
2. Hemifacial microsomia.
3. Midfacial distraction osteogenesis (apert, crouzan, Pfeiffer
syndromes).
4. Treacher collin syndrome.
5. Juvenile idiopathic arthritis.
28.
29. DO in preparation for orthognathic surgery
1. Pierre Robin sequence:
Micrognathia, glossoptosis and airway obstruction & may have undergone
mandibular distraction during infancy.
In these patient orthodontist/ orthognathic surgeon must pay close attention
to:
A. Underlying diagnosis of Pierre Robin sequence
B. Potential for addition mandibular growth
C. Potential for recurrent OSA & TMJ function
D. History of Pharyngeal flap surgery
30. DO in preparation for orthognathic surgery
2. Midface deficiency syndrome:
Lefort III and midface deficiency syndrome like
o Crouzan syndrome
o Apert syndrome
o Cranisynastosis syndrome
Midface advancement is delayed until skeletal maturity
Midfacial distraction is dictated by orbital glob relationship not occlusion
34. DO in preparation for orthognathic surgery
3. Combined midfacial and mandibular distraction for counter
clockwise rotation in Treacher Collins syndrome.
4. Unilateral or bilateral mandibular ramus distraction in patients with
progressive mandibular resorption, such as in juvenile idiopathic
arthritis.
5. Hemifacial microsomia patient
35. DO in lieu of conventional orthognathic
surgery
36. DO in lieu of conventional orthognathic surgery
There are some scenarios in which the orthognathic surgeon may
choose to use DO instead of conventional osteotomies for
correction of a dentofacial deformity.
Three types of situation that frequently dictates this
I. The need for large and/or complex movements.
II. Excessive scar tissue or other soft tissue limitation to planned
movement.
III. Expected need for bone grafting with acute movement.
37. DO in lieu of conventional orthognathic surgery
Bell and Guerrero proposed use of DO for movements exceeding
6mm in their 2007 textbook on the topic.
Bell WH, Guerrero CA. Distraction Osteogenesis of the Facial Skeleton.
Hamilton, ON: BC Decker; 2007.
38. DO in lieu of conventional orthognathic surgery
1. Maxillary DO in patients with repaired cleft lip and palate:
Patients with repaired cleft lip and palate may have significant
maxillary hypoplasia and dense scar tissue of the lip and palate.
There is some evidence that stability is inferior with conventional
techniques and improved with DO.
A metaanalysis, however, did not find a significant difference in
stability between the two techniques.
Austin SL, Mattick CR, Waterhouse PJ. Distraction osteogenesis versus
orthognathic surgery for the treatment of maxillary hypoplasia in cleft lip
and palate patients: a systematic review. Orthod Craniofac Res.
2015;18:96–108.
Chua HD, Hagg MB, Cheung LK. Cleft maxillary distraction versus orthognathic surgerywhich
one is more stable n 5 years? Oral Surg Oral Med Oral Pathol Oral RadiolEndod.
2010;109:803–814
39. DO in lieu of conventional orthognathic surgery
40. DO in lieu of conventional orthognathic surgery
41. DO in lieu of conventional orthognathic surgery
42. DO in lieu of conventional orthognathic surgery
2. Midface and maxillary DO in patients with hypoplasia syndromes
In patients with syndromic craniosynostosis, subcranial Le Fort III
osteotomy and midfacial distraction can be used to achieve
o Larger midfacial advancement with greater stability
o Less blood loss and without need for bone grafts and associated
donor site morbidity compared to standard techniques and bone
grafting.
43. DO in lieu of conventional orthognathic surgery
44. DO in lieu of conventional orthognathic surgery
45. DO in lieu of conventional orthognathic surgery
3. Mandibular antero-posterior DO:
DO may also be used in lieu of conventional orthognathic surgery to
achieve large and complex mandibular movements.
This technique is particularly useful in patients with
o Angle Class II malocclusions and severe mandibular hypoplasia
o Extreme facial asymmetry, and/or significant loss of posterior
vertical facial height requiring counterclockwise rotation of the
mandible for correction
46. DO in lieu of conventional orthognathic surgery
47. DO in lieu of conventional orthognathic surgery
48. DO in lieu of conventional orthognathic surgery
Distraction osteogenesis (DO) is a surgical technique that takes advantage of
natural wound healing mechanisms to augment bone and soft tissues. DO is
extremely versatile and can be applied to nearly any bone. In the craniofacial
skeleton, the cranial vault, midface, maxilla andmandible are themost common
sites for DO. This technique allows larger skeletal movements than could be
achieved with conventional techniques,
There is an important difference in the healing
process for DO compared to traumatic fracture
repair. Because of the controlled microtrauma
and slow expansion in DO, bone formation in
the distraction gap occurs by membranous rather
than endochondral ossification, and is mediated
by a series of growth factors, cytokines and extracellular
matrix proteins.
Latency is the time period from osteotomy
and device application to device activation. The
purpose of this delay is to allow formation of a
primary bone callus, thereby stimulating the
influx of biochemicals to support bone growth. Distraction is the phase during which the
device is gradually activated, and neoformation
of tissue occurs parallel to the vector of distraction.
17 The rate of activation may influence ossification
in the gap and expansion of surrounding issues; distracting too quickly may lead to nonunion
and/or increased neuropraxia,7 and activating
too slowly may lead to premature
consolidation. Consolidation begins after distraction is completed.
The distraction device remains in place and
acts as a stabilizer to prevent micromotion of the
separated segments as ossification occurs. Commonly
reported consolidation periods vary from
412 weeks17,21; 8 weeks has been found to be sufficient.
22 Inadequate consolidation, however, may
lead to nonunion.23
pert syndrome is a rare genetic condition that is apparent at birth. People with Apert syndrome can have distinctive malformations of the skull, face, hands, and feet. Apert syndrome is characterized by craniosynostosis, a condition in which the fibrous joints (sutures) between bones of the skull close prematurely..
The large maxillary advancement needed to correct the skeletal malocclusion may not be achievable with conventional techniques and bone grafting may be necessary for these large advancements.
A. Frontal, lateral, intraoral photographs and lateral cephalogram of a 15-year-old girl with left unilateral
complete cleft lip/palate and severe maxillary hypoplasia with 14mm of negative overjet.
6-year-old boy with Crouzon syndrome, severe obstructive sleep apnea, and intolerance of continuous
positive airway pressure (CPAP) treatment, who underwent Le Fort III subcranial osteotomy and midfacial
distraction.
A. Preoperative images demonstrating severe midfacial hypoplasia.
B. After Le Fort III osteotomy and during distraction phase, with rigid external distractor in place.
C. After midfacial distraction. The obstructive sleep apnea resolved, and the patient was discharged home with
no additional treatment.
A. Single vector distractor applied parallel to the mandibular inferior border, with an inverted-L osteotomy
posterior to the dentition, to allow antero-posterior advancement.
B. Curvilinear distractors with radius of curvature chosen based on planned movements.