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URGENT START PD
Daniel Schwartz, MD
February 8, 2013
Objectives
   Understand the rationale for urgent start
    peritoneal dialysis
   Learn how to implement urgent start PD at
    your centre

Slides available at: http://qx.md/urgent
HD vs PD
Which is better?
Randomized Trials

RCT data difficult to come by




Get full text at:
QxMD.com/r/14633146     http://qx.md/read
Observational Data
   Conflicting: PD no difference, a relative
    benefit, or a relative adverse effect upon
    survival
   Many reasons related to study design
   PD may provide short term survival advantage
                              Get full text at:
                              QxMD.com/r/22391139
From: Similar Outcomes With Hemodialysis and Peritoneal Dialysis in Patients With End-Stage Renal Disease
                                                                               Get full text at:
Arch Intern Med. 2011;171(2):110-118. doi:10.1001/archinternmed.2010.352       QxMD.com/r/20876398




Figure Legend:

Adjusted population survival curves comparing the outcome of peritoneal dialysis (PD) and hemodialysis (HD) patients with incident
end-stage renal disease in the United States stratified by cohort period. A, 1996-1998 Cohort: adjusted median life expectancy, 37.2
months for HD patients and 31.7 months for PD patients; B, 1999-2001 cohort: adjusted median life expectancy, 37.3 months for HD
patients and 33.0 months for PD patients; C, 2002-2004 cohort: adjusted median life expectancy, 38.4 months for HD patients and
36.6 months for PD patients; and D, overall: adjusted median life expectancy, 37.6 months for HD patients and 33.7 months for PD
patients.
CVC impacts association between
 modality and survival
    1-year mortality
      HD-AVF/AVG and PD similar
      HD-CVC 80% higher than PD

    Use of CVCs in incident HD patients largely
     accounts for the early survival benefit seen
     with PD




Get full text at:
QxMD.com/r/21511830
What do patients want?

50% chose PD




Get full text at:
QxMD.com/r/14633146
Costs of PD vs HD
Single payer perspective
3-year cumulative costs
• PD-only $58,724
• HD-only $175,996




Get full text at:
QxMD.com/r/22901772
Costs of PD vs HD
Single payer perspective
3-year cumulative costs
• PD-only $58,724
• HD-only $175,996
• HD-to-PD $114,503




Get full text at:
QxMD.com/r/22901772
Getting it right the first time
Cost effective
Optimal care?
   Avoid CVC start, Divert to PD start
   Advantages
     Consistent  with patient wishes
     Cost effective

     Better outcomes
Patient in front of you
   Wanted to start HD with an AVF
     GFR   now 7 and AVF hasn’t matured


   Planned on starting PD but now not sure
     Has   no permanent AV access


   Patient presents with new onset renal disease,
    GFR 6, K/HCO3 normal, volume status OK,
    anorexia, fatigue
Urgent Start PD an Option
   Buy in from the team
   Access to rapid education/orientation
   Access to rapid PD insertion
   Access to IPD post insertion
The slides available online
http://qx.md/urgent

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Urgent Start Peritoneal Dialysis

  • 1. URGENT START PD Daniel Schwartz, MD February 8, 2013
  • 2. Objectives  Understand the rationale for urgent start peritoneal dialysis  Learn how to implement urgent start PD at your centre Slides available at: http://qx.md/urgent
  • 3. HD vs PD Which is better?
  • 4. Randomized Trials RCT data difficult to come by Get full text at: QxMD.com/r/14633146 http://qx.md/read
  • 5. Observational Data  Conflicting: PD no difference, a relative benefit, or a relative adverse effect upon survival  Many reasons related to study design  PD may provide short term survival advantage Get full text at: QxMD.com/r/22391139
  • 6. From: Similar Outcomes With Hemodialysis and Peritoneal Dialysis in Patients With End-Stage Renal Disease Get full text at: Arch Intern Med. 2011;171(2):110-118. doi:10.1001/archinternmed.2010.352 QxMD.com/r/20876398 Figure Legend: Adjusted population survival curves comparing the outcome of peritoneal dialysis (PD) and hemodialysis (HD) patients with incident end-stage renal disease in the United States stratified by cohort period. A, 1996-1998 Cohort: adjusted median life expectancy, 37.2 months for HD patients and 31.7 months for PD patients; B, 1999-2001 cohort: adjusted median life expectancy, 37.3 months for HD patients and 33.0 months for PD patients; C, 2002-2004 cohort: adjusted median life expectancy, 38.4 months for HD patients and 36.6 months for PD patients; and D, overall: adjusted median life expectancy, 37.6 months for HD patients and 33.7 months for PD patients.
  • 7. CVC impacts association between modality and survival  1-year mortality  HD-AVF/AVG and PD similar  HD-CVC 80% higher than PD  Use of CVCs in incident HD patients largely accounts for the early survival benefit seen with PD Get full text at: QxMD.com/r/21511830
  • 8. What do patients want? 50% chose PD Get full text at: QxMD.com/r/14633146
  • 9. Costs of PD vs HD Single payer perspective 3-year cumulative costs • PD-only $58,724 • HD-only $175,996 Get full text at: QxMD.com/r/22901772
  • 10. Costs of PD vs HD Single payer perspective 3-year cumulative costs • PD-only $58,724 • HD-only $175,996 • HD-to-PD $114,503 Get full text at: QxMD.com/r/22901772
  • 11. Getting it right the first time Cost effective
  • 12. Optimal care?  Avoid CVC start, Divert to PD start  Advantages  Consistent with patient wishes  Cost effective  Better outcomes
  • 13. Patient in front of you  Wanted to start HD with an AVF  GFR now 7 and AVF hasn’t matured  Planned on starting PD but now not sure  Has no permanent AV access  Patient presents with new onset renal disease, GFR 6, K/HCO3 normal, volume status OK, anorexia, fatigue
  • 14. Urgent Start PD an Option  Buy in from the team  Access to rapid education/orientation  Access to rapid PD insertion  Access to IPD post insertion
  • 15. The slides available online http://qx.md/urgent