This document discusses the use of brachytherapy in treating head and neck cancers. It aims to deliver high doses of radiation directly to tumors while sparing surrounding normal tissues and minimizing side effects. Various unusual sites for brachytherapy are described, including the maxillary sinus, nasal vestibule, skin, ear canal, orbit, and parotid gland. Case studies demonstrate brachytherapy techniques like mould, interstitial, and sandwich applications. Doses, fractions, and treatment planning are also discussed.
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UNUSUAL SITES OF BRACHYTHERAPY IN HEAD AND NECK CANCER
1. UNUSUAL SITES OF BRACHYTHERAPY IN HEAD AND NECK CANCER
DR KANHU CHARAN PATRO
MD,DNB(RADIATION ONCOLOGY),MBA,FICRO,FAROI(USA),PDCR,CEPC
HOD,RADIATION ONCOLOGY
Mahatma Gandhi Cancer Hospital And Research Institute, Visakhapatnam
drkcpatro@gmail.com /M- +91-9160470564
2. GOALS
High dose to tumor tissue-Tumor control
Normal tissue sparing
Minimize long and short-term toxicities
Better Quality of life
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6. Brachytherapy
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SHORT DISTANCE
/CONTACT WITH
TUMOR
EXPERTISE NEEDED INVASIVE
PROCEDURE
ADEQUETLY
SPARING NORMAL
STRUCTURE
WELL ESTABLISHED
19. Case details
1. A 61-year-old male was previously admitted to another hospital and received
surgery because of left maxillary sinus squamous cell carcinoma (SCC) 6 years
ago.
2. Tumor regrowth was noted 2 years after the initial radical surgery. The patient
accepted local excision again for the recurrence, followed by external beam
radiotherapy.
3. Despite salvage treatment with surgery and external irradiation, the lesion
expanded as 4.8 × 4.4 × 4.0 cm3. Because the patient refused palliative
resection, we recommended technique of image-guided HDR interstitial
brachytherapy.
4. The total doses of 42 Gy in 12 fractions were delivered to the whole recurrent
tumor
26. The tumor is irradiated by a
standardized fractionation: 44
Gy total dose, 3 Gy per fraction,
except first and last fraction 4
Gy, two fractions per day (b.i.d.),
6 hr interval between the
fractions, maximum overall
treatment time 10 days
NASAL VESTIBULAR INTERSTITAL BRACHY
61. Case details
• Thirteen patients with advanced carcinomas of the parotid gland
were included and treated with 125I interstitial brachytherapy in
Peking University School and Hospital of Stomatology from January
2003 to December 2015.
• All patients were treated with 125I interstitial brachytherapy as a sole
modality for the primary tumor.
• Furthermore, all of them were treated with neck dissection
with/without adjunctive external beam radiotherapy for the neck,
simultaneously.
• The prescription dose of interstitial brachytherapy was 140 to160 Gy
72. • An 87-year-old man presented with epistaxis. A biopsy of a 1-
cm lesion at the anterior left nasal septum was positive for well-
differentiated squamous cell carcinoma.
• CT of the head and neck reveals the lesion (a). He was treated
with brachytherapy. T
• Ten stainless-steel needles were placed in the left nasal ala,
nasal tip, and left nasal septum and were afterloaded with 192Ir
wires.
• A total dose of 60 Gy was delivered over 3.5 days. CT
dosimetry was obtained and isodose distributions are shown on
an axial plane through the tumor
• The patient had no evidence of disease and no symptoms 3
years after treatment.