technology transfer offer

1. Technology Transfer Offer
Vrije Universiteit Brussel
Pathological Chemistry and Physiology
VUB - Diabetes Research Center, The Clinical Biology of Diabetes More info & contact:
MEBO - Pathological Chemistry and Physiology Research Group Technology Transfer Interface
R&D Department
“Trefoil-type” immunoassay Hugo Loosvelt
A “trefoil type” immunoassay has been developed to simultaneously [T]: +32 (0)2 629 38 65 or 22 07
determine the concentrations of proinsulin and C-peptide, leading to a [E]: hloosvel@vub.ac.be
highly precise ratio determination (see figure, grey = C-peptide, red = [W]: www.vub.ac.be/technologytransfer
insulin, red+grey = proinsulin).
Technology Transfer Interface • R&D Department
Vrije Universiteit Brussel • Pleinlaan 2 • B-1050 Brussels • Belgium
E-mail: rd.interface@vub.ac.be • W: www.vub.ac.be/technologytransfer
Phone: +32 (0)2 629 22 07 • +32 (0)2 629 21 08

2. Technology Transfer Offer
Vrije Universiteit Brussel
Technology Description / Special Features IP Status
Patent granted in Europe, pending in US
A “trefoil type” immunoassay has been developed
to simultaneously determine the concentrations of
Collaboration Details
proinsulin and C-peptide, leading to a highly precise
Looking for an industrial partner
ratio determination.
Inventors
Pieter De Pauw, Dr. Sc.
Innovation Strengths / Competitive Advantage
“Trefoil-type” immunoassay simultaneously measures
Keywords
two or more related molecules, using only one capture
Proinsulin, C-peptide, ratio, multiplex, immunoassay
antibody.
Advantages:
- The sample history is exactly the same for all analytes
(freeze/thaw, etc…)
- Reduced sample manipulation (1x taking out from
freezer instead of n x)
- Reduced sample volume needed to perform all analysis
(1/n x)
- Absence of any sample pipetting error on ratio
determination
- Reduced personnel and material cost (one performance
for n analytes)
Market Opportunities / Industrial Target Group
The PI/C is a parameter for pancreas functionality. It has
predictive potential for Type 1 diabetes and vascular
diseases, two pathologies with high incidence over the
world.
Industrial target group: biomedical analysis kits / devices