Diseases threaten homeostasis by disrupting the normal functioning of the body. The main causes of disease include pathogens, inherited disorders, exposure to toxins, poor nutrition, organ malfunctions, and high-risk behaviors. Pathogens that cause disease include bacteria, viruses, fungi, and parasites. Cancer is an example of a genetic disease caused by uncontrolled cell division due to genetic mutations, which can be caused by exposure to chemicals and radiation.