My top respiratory-related ICM papers of 2018

1. My 2018 top five respiratory-related ICU papers
Dr. Charlotte Summers
University of Cambridge

2. BREATHE
Effect of Protocolized Weaning With Early
Extubation to Noninvasive Ventilation vs Invasive
Ventilation on Time to Liberation From Mechanical
Ventilation Among Patients With Respiratory Failure
Perkins et al. JAMA 2018; 320:1881-1888.

3. EOLIA
Extracorporeal Membrane Oxygenation for Severe
Acute Respiratory Distress Syndrome
Combes et al. N Engl J Med 2018; 378:1965-1975.

4. HIGH
Effect of High-Flow Nasal Oxygen vs Standard
Oxygen on 28-day Mortality in
Immunocompromised Patients with Acute
Respiratory Failure. The HIGH Randomized Clinical
Trial
Azoulay et al. JAMA 2018; 320:2099-2107.

5. PReVENT
Effect of a Low vs Intermediate Tidal Volume
Strategy on Ventilator-Free Days in Intensive Care
Unit Patients Without ARDS. The PReVENT Trial
Simonis et al. JAMA 2018; 320:1872-1880.

6. HFNO in bronchiolitis
A Randomised Trial of High-Flow Oxygen Therapy in
Infants with Bronchiolitis
Franklin et al. New Eng J Med 2018; 378:1121-1131.

7. www.thebottomline.org.uk
For great summaries of these papers, and more:

8. cs493@medschl.cam.ac.uk
http://anaesthetics.medschl.cam.ac.uk/ccg/
@CamICU_Research or @charlot_summers