This document provides a list and overview of the top 10 Node.js frameworks to use in 2021. It discusses frameworks like Express.js, Hapi, Koa, Socket.io, Meteor, Sails.js, Total.js, Feather.js, NestJS, and Loopback. For each framework, it outlines its core features, pros, cons, and compares them. The frameworks vary in their functionality, with some being better suited for APIs, real-time apps, or full-stack development. Express.js and NestJS are highlighted as two of the most popular and full-featured options overall.